Cryptococcus neoformans meningitis in the rat

Laboratory Investigation

Volumn 75, Issue 6, 1996, Pages 759-770

  Goldman, David L ^a   Casadevall, Arturo ^a   Cho, Youngsoo ^a   Lee, Sunhee C ^a  

^a ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD11B ANTIGEN; CD4 ANTIGEN; CD8 ANTIGEN; GLIAL FIBRILLARY ACIDIC PROTEIN; GLYCOPROTEIN P 15095; NITRIC OXIDE SYNTHASE;

ANIMAL MODEL; ANIMAL TISSUE; ANTIGEN EXPRESSION; APOPTOSIS; ARTICLE; CEREBROSPINAL FLUID; COLONY FORMING UNIT; CONTROLLED STUDY; CRYPTOCOCCUS NEOFORMANS; ETIOLOGY; FUNGAL MENINGITIS; GLIA CELL; GRANULOMATOUS INFLAMMATION; HOST RESISTANCE; INOCULATION; MACROPHAGE; NONHUMAN; PRIORITY JOURNAL; RAT; T LYMPHOCYTE ACTIVATION;

ANIMALS; ANTIBODIES, MONOCLONAL; ANTIGENS, DIFFERENTIATION, T-LYMPHOCYTE; APOPTOSIS; BRAIN; CRYPTOCOCCUS NEOFORMANS; GRANULOMA; HUMANS; IMMUNOHISTOCHEMISTRY; INFLAMMATION; LUNG; LYMPHOCYTE ACTIVATION; MACROPHAGES; MALE; MENINGITIS, CRYPTOCOCCAL; NITRIC OXIDE SYNTHASE; RATS; RATS, INBRED F344; SPLEEN; T-LYMPHOCYTES;

EID: 0030465546     PISSN: 00236837     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (28)

1. Albina JE, Abate JA, and Henry WL (1991). Nitric oxide production is required for murine resident peritoneal macrophages to suppress mitogen-stimulated T cell proliferation: Role of IFN-γ in the induction of nitric oxide-synthesizing pathway. J Immunol 147:144-149.
2. Albina JE, Cui S, Mateo RB, and Reichner JS (1993). Nitric oxide-mediated apoptosis in murine peritoneal macrophages. J Immunol 150:5080-5085.
3. Alspaugh JA and Granger DL (1991). Inhibition of Cryptococcus neoformans replication by nitric oxide supports the role of these molecules as effector of macrophage-mediated cytostasis. Infect Immun 59:2291-2296.
4. Blasi E, Barluzzi R, Mazzolla R, Mosci P, and Bistoni F (1992). Experimental model of intracerebral infection with Cryptococcus neoformans: Roles of phagocytes and opsonization. Infect Immun 60:3682-3688.
5. Boje KMK (1995). Inhibition of nitric oxide synthase partially attenuates alterations in the blood-cerebrospinal fluid barrier during experimental meningitis in the rat. Eur J Pharmacol 272:297-300.
6. Buster BL, Weintrob AC, Townsend GC, and Scheld WM (1995). Potential role of nitric oxide in the pathophysiology of experimental bacterial meningitis in rats. Infect Immun 63: 3835-3839.
7. Cameron ML, Granger DL, Weinberg JB, Kozumbo WJ, and Koren HS (1990). Human alveolar and peritoneal macrophages mediate fungistasis independently of L-arginine oxidation to nitrite or nitrate. Am Rev Respir Dis 142:1313-1319.
8. Campbell IL, Samimi A, and Chiang C-S (1994). Expression of the inducible nitric oxide synthase: Correlation with neuropathology and clinical features in mice with lymphocytic choriomeningitis. J Immunol 153:3622-3629.
9. Feinstein DL, Galea E, and Reis DJ (1993). Norepinephrine suppresses inducible nitric oxide synthase activity in rat astroglial cultures. J Neurochem 60:1945-1948.
10. Goldman D, Cho Y, Zhao M-L, Casadevall A, and Lee SC (1996). Expression of inducible nitric oxide synthase in rat pulmonary Cryptococcus neoformans granulomas. Am J Pathol 148:1275-1282.
11. Goldman D, Lee SC, and Casadevall A (1994). Pathogenesis of pulmonary cryptococcosis in the rat. Infect Immun 62: 4755-4761.
12. + T cell-dependent acquired state of immunity that protects the brain against Cryptococcus neoformans. J Immunol 152:2344-2350.
13. + T cells. J Exp Med 173:793-800.
14. Lee SC, Casadevall A, and Dickson DW (1996a). Immunohistochemical localization of capsular polysaccharide antigen in the central nervous system cells in cryptococcal meningoencephalitis. Am J Pathol 148:1267-1274.
15. Lee SC, Dickson DW, Brosnan CF, and Casadevall A (1994). Human astrocytes inhibit the growth of Cryptococcus neoformans by a nitric oxide-mediated mechanism. J Exp Med 180:365-369.
16. Lee SC, Dickson DW, and Casadevall A (in press, 1996b). Pathology of cryptococcal meningoencephalitis: Analysis of 27 patients with pathogenetic implications. Hum Pathol.
17. Lee SC, Kress Y, Zhao M-L, Dickson DW, and Casadevall A (1995). Cryptococcus neoformans survive and replicate in human microglia. Lab Invest 73:871-879.
18. Lovchik JA, Lyons CR, and Lipscomb MF (1995). A role for gamma interferon-induced nitric oxide in pulmonary clearance of Cryptococcus neoformans. Am J Respir Cell Mol Biol 13:116-124.
19. + T cells in vivo decreases pulmonary clearance of a moderately virulent strain of Cryptococcus neoformans. J Lab Clin Med 121:765-773.
20. Molloy A, Laochumroonvorapong P, and Kaplan G (1994). Apoptosis, but not necrosis, of infected monocytes is coupled with killing of intracellular Bacillus Calmette-Guerin. J Exp Med 180:1499-1509.
21. Mozaffarian N, Berman JW, and Casadevall A (1995). Immune complexes increase nitric oxide production by interferon-gamma stimulated murine macrophage-like J774.16 cells. J Leukoc Biol 57:657-662.
22. Mukherjee S, Lee SC, Mukherjee J, Scharff MD, and Casadevall A (1994). Antibody to Cryptococcus neoformans modifies the course of intravenous infection in mice. Infect Immun 62:1079-1088.
23. Nathan C and Xie Q-W (1994). Regulation of biosynthesis of nitric oxide. J Biol Chem 269:13725-13728.
24. Perfect JR, Hobbs MM, Granger DL, and Durack DT (1988). Cerebrospinal fluid macrophage response to experimental cryptococcal meningitis: Relationship between in vivo and in vitro measurement of cytotoxicity. Infect Immun 56:849-853.
25. Perfect JR, Lang SDR, and Durack DT (1980). Chronic cryptococcal meningitis: A new experimental model in rabbits. Am J Pathol 101:177-194.
26. Pfister HW, Bernatowicz A, Kodel U, and Wick M (1995). Nitric oxide production in bacterial meningitis. J Neurol Neurosurg Psychiatry 58:384-385.
27. Vouldoukis I, Riveros-Moreno V, Dugas B, Quaaz F, Becherel P, Debre P, Moncada S, and Mossalayi MD (1995). The killing of Leishmania major by human macrophages is mediated by nitric oxide induced after ligation of the Fc∈ RII/CD23 surface antigen. Proc Natl Acad Sci USA 92:7804-7808.
28. Zychlinsky A, Fitting C, Cavaillon J-M, and Sansonetti PJ (1994). Interleukin 1 is release by murine macrophages during apoptosis induced by Shiegella flexneri. J Clin Invest 94: 1328-1332.