The role of G-protein coupled receptor kinases in the regulation of muscarinic cholinergic receptors

Progress in Brain Research

Volumn 109, Issue , 1996, Pages 169-179

  Hosey, M M ^a   DebBurman, S K ^a   Pals Rylaarsdam, R ^a   Richardson, R M ^a   Benovic, J L ^a  

^a NORTHWESTERN UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLCHOLINE; CARBACHOL; GUANINE NUCLEOTIDE BINDING PROTEIN; MUSCARINIC AGENT; MUSCARINIC RECEPTOR; RECEPTOR SUBTYPE;

ANIMAL CELL; CONFERENCE PAPER; DESENSITIZATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RECEPTOR DOWN REGULATION;

EID: 0030465210     PISSN: 00796123     EISSN: None     Source Type: Book Series    
DOI: 10.1016/s0079-6123(08)62099-3     Document Type: Conference Paper

References (64)

1. H. Attramadal J.L. Arriza C. Aoki T.M. Dawson J. Codina M.M. Kwatra S.H. Snyder M.G. Caron R.J. Lefkowitz β-arrestin2, a novel member of the Arrestinβ-arrestin gene family. J. Biol. Chem. 1 1992 17882 17890
2. J.L. Benovic R.H. Strasser M.G. Caron R.J. Lefkowitz β-adrenergic receptor kinase: Identification of a novel protein kinase that phosphorylates the agonist-occupied form of the receptor. Proc. Natl. Acad. Sci. USA 1 1986 2797 2801
3. J.L. Benovic F. Mayor Jr. C. Staniszewski R.J. Lefkowitz M.G. Caron Purification and characterization of β-adrenergic receptor kinase. J. Biol. Chem. 1 1987 9026 9032
4. I. Boekhoff J. Inglese S. Scleicher W.J. Koch R.J. Lefkowitz H. Breer Olfactory desensitization requires membrane-targetting of receptor kinase mediated by βγ-subunits of heterotrimeric G proteins. J. Biol. Chem. 1 1994 37 40
5. C.-Y. Chen S.B. Dion C.M. Kim J.L. Benovic β-adrenergic receptor kinase: agonist-dependent receptor binding promotes kinase activation. J. Biol. Chem. 1 1993 7825 7831
6. T.M. Dawson J.L. Arriza D.E. Jaworsky F.F. Borisy H. Attramadal R.J. Lefkowitz G.V. Ronnett β-adrenergic receptor kinase-2 and β-arrestin 2 as mediators of odorant induced desensitization. Science 1 1993 825 829
7. S.K. Deb Burman P. Kunapuli J.L. Benovic M.M. Hosey Agonist-dependent phosphorylation of human muscarinic receptors in Spodoptera frugiperda insect cell membranes by G protein-coupled receptor kinases. Mol. Pharmacol. 1 1995 224 233
8. S.K. Deb Burman J. Ptasienski E. Boetticher J.L. Lomasney J.L. Benovic M.M. Hosey Lipid-mediated regulation of G protein-coupled receptor kinases 2 and 3. J. Biol. Chem. 1 1995 5742 5747
9. E.E. El-Fakahany B.E. Alger W.S. Lai T.A. Pitler P.F. Worley J.M. Baraban Neuronal muscarinic responses: role of protein kinase C. FASEB J. 1 1988 2575 2583
10. T.J. Gibson M. Hyvonen A. Musacchio M. Saraste PH domain: the first anniversary. Trends Biochem. Sci. 1 1994 349 352
11. E.N. Gorodovikova A.A. Gimelbrant I.I. Senin P.P. Philippov Recoverin mediates the calcium effect upon rhodopsin phosphorylation and cGMP hydrolysis in bovine retina rod cells. FEBS Lett. 1 1994 187 190
12. V.V. Gurevich J.L. Benovic Cell-free expression of visual arrestin: truncation mutagenesis identifies multiple domains involved with rhodopsin interaction. J. Biol. Chem. 1 1992 21919 21923
13. V.V. Gurevich J.L. Benovic Visual arrestin interaction with rhodopsin: Sequential multisite binding ensures strict selectivity toward light-activated phosphorylated rhodopsin. J. Biol. Chem. 268 1993 11628 11638
14. V.V. Gurevich R.M. Richardson C.M. Kim M.M. Hosey Binding of wild type and chimeric arrestins to the m2 muscarinic cholinergic receptor. J. Biol. Chem. 1 1993 16879 16882
15. 2-adrenergic and m2 muscarinic cholinergic receptors. J. Biol. Chem. 1 1995 720 731
16. K. Haga T. Haga Dual regulation by G proteins of agonist-dependent phosphorylation of muscarinic acetylcholine receptors. FEBS Lett. 1 1990 43 47
17. K. Haga T. Haga Activation of G protein βγ subunits of agonist- and light-induced phosphorylation of muscarinic acetylcholine receptors and rhodopsin. J. Biol. Chem. 1 1992 2222 2227
18. K. Haga K. Kameyama T. Haga Synergistic activation of a G protein-coupled receptor kinase by G protein βγ subunits and Mastoparan or related peptides. J. Biol. Chem. 1 1994 12594 12599
19. P. Hargrave H.E. Hamm Regulation of visual transduction. D.R. Sibley M.D. Houslay Regulation of Signal Transduction Pathways by Desensitization and Amplification. 1994 Wiley New York 25 67
20. J.E. Harlan P.J. Hajduk H.S. Yoon S.W. Fesik Pleckstrin homology domains bind to phosphatidylinositol-4,5-bisphosphate. Nature 1 1994 168 170
21. M.M. Hosey Desensitization of Muscarinic cholinergic receptors and the role of protein phosphorylation. D.R. Sibley M.D. Houslay Regulation of Signal Transduction Pathways by Desensitization and Amplification. 1994 Wiley New York 113 128
22. J. Inglese J.F. Glickman W. Lorenz M.G. Caron R.J. Lefkowitz Isoprenylation of a protein kinase: requirement of farnesylation/α-carboxyl methylation for full enzymatic activity of rhodopsin kinase. J. Biol. Chem. 1 1992 1422 1425
23. J. Inglese W.J. Koch M.G. Caron R.J. Lefkowitz Isoprenylation in regulation of signal transduction by G protein-coupled receptor kinases. Nature 1 1992 147 150
24. J. Inglese N.J. Freedman W.J. Koch R.J. Lefkowitz Structure and mechanism of the G protein-coupled receptor kinases. J. Biol. Chem. 1 1993 23735 23738
25. K. Kameyama K. Haga T. Haga O. Moro W. Sadee Activation of GTP binding protein and a GTP-binding-protein-coupled receptor kinase (β-adrenergic receptor kinase 1) by a muscarinic receptor m2 mutant lacking phosphorylation sites. Eur. J. Biochem. 1 1994 267 276
26. S. Kawamura Rhodopsin phosphorylation as a mechanism of cyclic GMP phosphodiesterase regulation by S-modulin. Nature 1 1993 855 857
27. D.J. Kelleher G.J. Johnson Characterization of rhodopsin kinase purified from bovine rod outer segments. J. Biol. Chem. 1 1990 2632 2639
28. V.A. Klenchin P.D. Calvert M.D. Bownds Inhibition of rhodopsin kinase by recoverin: Further evidence for a negative feedback system in phototransduction. J. Biol. Chem. 1 1995 16147 16152
29. W.J. Koch J. Inglese W.C. Stone R.J. Lefkowitz The binding site for the βγ subunits of heterotrimeric G proteins on the β-adrenergic receptor kinase. J. Biol. Chem. 1 1993 680 685
30. 2-adrenergic receptor. J. Biol. Chem. 1 1994 13084 13087
31. P. Kunapuli J.J. Onorato M.M. Hosey J.L. Benovic Expression, purification and characterization of G protein-coupled receptor kinase GRK5. J. Biol. Chem. 1 1994 1099 1105
32. P. Kunapuli V.V. Gurevich J.L. Benovic Phospholipid-stimulated autophosphorylation activates G protein-coupled receptor kinase GRK5. J. Biol. Chem. 1 1994 10109 10212
33. M.M. Kwatra M.M. Hosey Phosphorylation of the cardiac muscarinic receptor in the intact chick heart and its regulation by a muscarinic agonist. J. Biol. Chem. 1 1986 12429 12432
34. M.M. Kwatra E. Leung A.C. Maan K.K. McMahon J. Ptasienski R. Green M.M. Hosey Correlation of agonist-induced phosphorylation of chick heart muscarinic receptors with receptor desensitization. J. Biol. Chem. 1 1987 16314 16321
35. M.M. Kwatra J. Ptasienski M.M. Hosey The porcine heart m2 muscarinic receptor: agonist-induced phosphorylation and comparison of properties with chick heart receptor. Mol. Pharmacol. 1 1989 553 558
36. M.M. Kwatra J.L. Benovic M.G. Caron R.J. Lefkowitz M.M. Hosey Phosphorylation of the chick heart muscarinic receptor with the β-adrenergic receptor kinase. Biochemistry 1 1989 4543 4547
37. S.B. Liggett R.J. Lefkowitz Adrenergic receptor-coupled adenylyl cyclase systems: regulation of receptor function by phosphorylation, sequestration and down regulation. D.R. Sibley M.D. Houslay Regulation of Signal Transduction Pathways by Desensitization and Amplification. 1994 Wiley New York 71 98
38. W.C. Liles D.D. Hunter K.E. Meier N.M. Nathanson Activation of protein kinase C induces rapid internalization and subsequent degradation of muscarinic acetylcholine receptors in neuroblastoma cells. J. Biol. Chem. 1 1986 5307 5313
39. 2-adrenergic receptor desensitization: delineation with specific inhibitors. J. Biol. Chem. 1 1990 3202 3209
40. 2-adrenergic receptor and rhodopsin systems. J. Biol. Chem. 1 1992 8558 8564
41. W.J. Lorenz J. Inglese K. Palczewski J.J. Onorato M.G. Caron R.J. Lefkowitz The receptor kinase family: Primary structure of the rhodopsin kinase family reveals similarities to the β-adrenergic receptor kinase. Proc. Natl. Acad. Sci. USA 1 1991 8715 8719
42. R.P. Loudon J.L. Benovic Expression, purification and characterization of G protein-coupled receptor kinase GRK6. J. Biol. Chem. 1 1994 22691 22697
43. F. Mayor Jr. J.L. Benovic M.G. Caron R.J. Lefkowitz Somatostatin induces translocation of the β-adrenergic receptor kinase and desensitizes somatostatin receptors in S49 lymphoma cells. J. Biol. Chem. 1 1987 6468 6471
44. A. Musacchio T. Gibson P Rice J. Thompson M. Saraste The PH domain: a common piece in the structural patchwork of signalling proteins. Trends Biochem. Sci. 1 1993 343 348
45. S.A. Orellana P.A. Solski J.H. Brown Phorbol ester inhibits phosphoinositide hydrolysis and calcium mobilization in cultured astrocytoma cells. J. Biol. Chem. 1 1985 5236 5239
46. K. Palczewski J.L. Benovic G protein-coupled receptor kinases. Trends Biochem. Sci. 1 1991 387 391
47. K. Palczewski J. Buczylko M.W. Kaplan A.S. Polans J.W. Crabb Mechanism of rhodopsin kinase activation. J. Biol. Chem. 1 1991 12949 12955
48. R. Pals-Rylaarsdam Y. Xu P. Witt-Enderby J.L. Benovic M.M. Hosey Desensitization and internalization of the m2 muscarinic acetylcholine receptor are directed by independent mechanisms. J. Biol. Chem. 1 1995 29004 29011
49. T. Pawson Protein modules and signalling networks. Nature 1 1995 573 579
50. 2-adrenergic receptors permit receptor resensitization. Mol. Pharmacol. 1 1995 666 676
51. J.A. Pitcher J. Inglese J.B. Higgins J.L. Arriza P.J. Casey C. Kim J.L. Benovic M.M. Kwatra M.G. Caron R.J. Lefkowitz Role of βγ subunits of G proteins in targetting β-adrenergic receptor kinase to membrane-bound receptors. Science 1 1992 1264 1267
52. R.T. Premont J. Inglese R.J. Lefkowitz Protein kinases that phosphorylate activated G protein-coupled receptors. FASEB J. 1 1995 175 182
53. R.M. Richardson M.M. Hosey Agonist-independent phosphorylation of purified cardiac muscarinic cholinergic receptors by protein kinase C. Biochemistry 1 1990 8555 8561
54. R.M. Richardson M.M. Hosey Agonist-induced phosphorylation and desensitization of human m2 muscarinic acetylcholine receptors in Sf9 insect cells. J. Biol. Chem. 1 1992 22245 22249
55. R.M. Richardson J. Ptasienski M.M. Hosey Protein kinase C-mediated phosphorylation of chick heart muscarinic cholinergic receptors. J. Biol. Chem. 1 1992 10127 10132
56. R.M. Richardson C. Kim J.L. Benovic M.M. Hosey Phosphorylation and desensitization of human m2 muscarinic acetylcholine receptors by two isoforms of β-adrenergic receptor kinase. J. Biol. Chem. 1 1993 13650 13656
57. S. Schleicher I. Boekhoff J.L. Arriza R.J. Lefkowitz H. Breer A β-adrenergic receptor kinase-like enzyme is involved in olfactory signal termination. Proc. Natl. Acad. Sci. USA 1 1993 1420 1424
58. t. J. Biol. Chem. 1 1995 2112 2119
59. H. Shichi R.L. Somers Light-dependent phosphorylation of rhodopsin: purification and properties of rhodopsin kinase. J. Biol. Chem. 1 1978 7040 7046
60. R.H. Stoffel R.R. Randall R.T. Premont R.J. Lefkowitz J. Inglese Palmitoylation of G protein-coupled receptor kinase, GRK6: lipid modification diversity in the GRK family. J. Biol. Chem. 1 1994 27791 27794
61. 1-induced translocation of the β-adrenergic receptor kinase: evidence that the kinase may act on multiple adenylate cyclase-coupled receptors. Proc. Natl. Acad. Sci. USA 1 1986 6362 6366
62. A.B. Tobin D.G. Lambert S.R. Nahorski Rapid agonist-induced phosphorylation of m3-muscarinic receptors revealed by immunoprecipitation. J. Biol. Chem. 1 1993 9817 9823
63. H.S. Yoon P.J. Hadjuk A.M. Petros E.T. Olejniczak R.P. Meadows S.W. Fesik Solution structure of a pleckstrin-homology domain. Nature 1 1994 672 679
64. S.S. Yu R.J. Lefkowitz W.P. Hausdorff β-adrenergic receptor sequestration: A potential mechanism of receptor resensitization. J. Biol. Chem. 1 1993 337 341