Isolation of nicotianamine as a gelatinase inhibitor

Journal of Antibiotics

Volumn 49, Issue 12, 1996, Pages 1284-1285

  Suzuki, Keiko ^a   Shimada, Kohei ^b   Nozoe, Shigeo ^c   Tanzawa, Kazuhiko ^b   Ogita, Takeshi ^a  

^a Biomedical Research Laboratories   (Japan)

^b DAIICHI SANKYO CO   (Japan)

^c TOHOKU UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

GELATINASE B; GELATINASE INHIBITOR; MUGINEIC ACID; NICOTIANAMINE; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; DRUG ISOLATION; DRUG POTENCY; DRUG STRUCTURE; ENZYME INHIBITION; FERMENTATION; PRIORITY JOURNAL;

EID: 0030464320     PISSN: 00218820     EISSN: None     Source Type: Journal    
DOI: 10.7164/antibiotics.49.1284     Document Type: Article

References (5)

1. MATRISIAN, L. M.: Metalloproteinases and their inhibitors in matrix remodeling. Trends in Gentics 6: 121-125, 1990
2. OGITA, T.; A. SATO, R. ENOKITA, K. SUZUKI, M. ISHII, T. NEGISHI, T. OKAZAKI, K. TAMAKI & K. TANZAWA: Matlystatins, new inhibitors of type IV collagenases from Actinomadura atramentaria. I. Taxonomy, fermentation, isolation, and physico-chemical properties of matlystatin-group compounds. J. Antibiotics 45: 1723-1732, 1992
3. TANZAWA, K.; M. ISHII, T. OGITA & K. SHIMADA: Matlystatins, new inhibitors of type IV collagenases from Actinomadura atramentaria. II. Biological activities. J. Antibiotics 45: 1733-1737, 1992
4. RIPPERGER, H. & K. SCHREBER: Nicotianamine and analogous amino acid, endogenous iron carriers in higher plants. Heterocycles 17: 447-461, 1982
5. TAKEMOTO, T.; K. NOMOTO, S. FUSHIYA, R. OUCHI, G. KUSANO, H. HIKINO, S. TAKAGI, Y. MATSUURA & M. KAKUDO: Structure of mugineic acid, a new amino acid possessing an iron-chelating activity from roots washings of water-cultured Horderum vulgare L. Proc. Jpn. Acad. 54: B 469, 1978