Apoptosis in antibody-dependent monocyte-mediated cytotoxicity with monoclonal antibody 17-1A against human colorectal carcinoma cells: Enhancement with interferon γ

Cancer Immunology Immunotherapy

Volumn 43, Issue 4, 1996, Pages 220-225

  Takamuku, Kiyoshi ^a   Baba, Kinya ^a   Arinaga, Shinya ^a   Li, Jian ^a   Mori, Masaki ^a   Akiyoshi, Tsuyoshi ^a  

^a KYUSHU UNIVERSITY   (Japan)

Author keywords

17 1A; antibody dependent cell mediated cytotoxicity; apoptosis; interferon ; monocyte

Indexed keywords

DNA FRAGMENT; GAMMA INTERFERON; MONOCLONAL ANTIBODY; SUPEROXIDE; TUMOR NECROSIS FACTOR ALPHA;

ADULT; ANTIBODY DEPENDENT CELLULAR CYTOTOXICITY; APOPTOSIS; ARTICLE; CANCER CELL CULTURE; GASTROINTESTINAL CARCINOMA; HUMAN; HUMAN CELL; MONOCYTE; PRIORITY JOURNAL;

ANTIBODIES, MONOCLONAL; ANTIBODY-DEPENDENT CELL CYTOTOXICITY; ANTINEOPLASTIC AGENTS; APOPTOSIS; CHROMIUM RADIOISOTOPES; COLORECTAL NEOPLASMS; DNA, NEOPLASM; DRUG SYNERGISM; HUMANS; IMMUNOTHERAPY; INTERFERON-GAMMA, RECOMBINANT; MONOCYTES; REACTIVE OXYGEN SPECIES; SUPEROXIDE DISMUTASE; TUMOR CELLS, CULTURED; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0030463986     PISSN: 03407004     EISSN: None     Source Type: Journal    
DOI: 10.1007/s002620050325     Document Type: Article

References (31)

1. 2+ concentration and DNA fragmentation. Cancer Res 52: 1342
2. Blottiere HM, Douillard J-Y, Koprowski H, Steprowski Z (1990) Humoral and cellular reponses of colorectal cancer patients treated with monoclonal antibodies and interferon-γ. Cancer Immunol Immunother 32: 29
3. Cui S, Reichner JS, Mateo RB, Albina JE (1994) Activated murine macrophages induce apoptosis in tumor cells through nitric oxide-dependent or -independent mechanisms. Cancer Res 54: 2462
4. Curnow SJ, Gelennie MJ, Stevenson GT (1993) The role of apoptosis in antibody-dependent cellular cytotoxicity. Cancer Immunol Immunother 36: 149
5. Duke RC, Cohen JJ, Chervenak R (1986) Differences in target cell DNA fragmentation induced by mouse cytotoxic T lymphocytes and natural killer cells. J Immunol 137: 1442
6. Frundlich B, Avdalovic N (1983) Use of gelatin/plasma coated flasks for isolating human peripheral blood monocytes. J Immunol Methods 62: 31
7. Gavrieli Y, Sherman Y, Ben-Sasson SA (1992) Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation. J Cell Biol 119: 493
8. Johnson WJ, Steplewski Z, Matthews TJ, Hamilton TA, Koprowski H, Adams DO (1986) Cytotoxic interactions between murine macrophages, tumor cells, and monoclonal antibodies: characterization of lytic conditions and requirements for effector activation. J Immunol 136: 4704
9. Kishimoto H, Surh C, Sprent J (1995) Upregulation of surface markers on dying thymocytes. J Exp Med 181: 649
10. Knight CRL, Rees RC, Platts A, Johnson T, Griffin M (1993) Interleukin-2-activated human effector lymphocytes mediate cytotoxicity by inducing apoptosis in human leukemia and solid tumor target cells. Immunology 79: 535
11. Laster SM, Wood JG, Gooding LR (1988) Tumor necrosis factor can induce both apoptic and necrotic forms of cell lysis. J Immunol 141: 2629
12. Masucci G, Lindemalm C, Frodin J-E, Hagstrom B, Mellstedt H (1988) Effect of human blood mononuclear cell populations in antibody dependent cellular cytotoxicity (ADCC) using two murine (CO17-1A and Br55-2) and one chimeric (17-1A) monoclonal antibodies against a human colorectal carcinoma cell line (SW948). Hybridoma 7: 429
13. Masucci G, Wersall P, Ragnhammar P, Mellstedt H (1989) Granulocyte-monocyte-colony-stimulating factor augments the cytotoxic capacity of lymphocytes and monocytes in antibody-dependent cellular cytotoxicity. Cancer Immunol Immunother 29: 288
14. Mellstedt H, Frodin J-E, Masucci G, Ragnhammar P, Fagerberg J, Hjelm A-L, Shetye J, Wersall P, Osterborg A (1991) The therapeutic use of monoclonal antibodies in colorectal carcinoma. Semin Oncol 18: 462
15. Nathan C, Cohn Z (1980) Role of oxygen-dependent mechanisms in antibody-induced lysis of tumor cells by activated macrophages. J Exp Med 152: 198
16. Nathan CF, Predergast TJ, Wiebe ME, Stanley ER, Platzer E, Remold HG, Weite K, Rubin BY, Murray HW (1988) Activation of human macrophages: comparison of other cytokines with interferon-γ. J Exp Med 167: 712
17. Ortaldo J, Woodhouse C, Morgan AC, Herberman R, Cheresh D, Reisfeld R (1987) Analysis of effector cells in human antibody-dependent cellular cytotoxicity with murine monoclonal antibodies. J Immunol 138: 3566
18. Pullyblank A-M, Guillou PJ, Monson JRT (1995) Interleukin 1 and tumor necrosis factor alpha may be responsible for the lytic mechanism during anti-tumor antibody-dependent cell-mediated cytotoxicity. Br J Cancer 72: 601
19. Ragnhammar P, Fagerberg J, Frodin J-E, Hjelm A-L, Lindemalm C, Magnusson I, Masucci G, Mellstedt H (1993) Effect of monoclonal antibody 17-1A and GM-CSF in patients with advanced carcinoma - long lasting, complete remissions can be induced. Int J Cancer 53: 751
20. Ragnhammar P, Frodin J-E, Trotta PP, Mellstedt H (1994) Cytotoxicity of white blood cells activated by granulocyte-colony-stimulating factor, granulocyte/macrophage-colony-stimulating factor and macrophage-colony-stimulating factor against tumor cells in the presence of various monoclonal antibodies. Cancer Immunol Immunother 39: 254
21. Riethmuller G, Schneider-Gadicke E, Schlimok G, Schmiegel W, Raab R, Hoffken K, Gruber R, Pichlmaier H, Hirche H, Pichlmayr R, Buggisch P, Witte J, The German Cancer Aid 17-1A Study Group (1994) Randomised trial of monoclonal antibody for adjuvant therapy of resected Dukes' C colorectal carcinoma. Lancet 343: 1177
22. Saleh MN, LoBuglio AF, Wheeler RH, Rogers KJ, Haynes A, Lee JY, Khazaeli MB (1990) A phase II trial of murine monoclonal antibody 17-1A and interferon-γ: clinical and immunological data. Cancer Immunol Immunother 32: 185
23. Shi L, Kraut RP, Aebersold R, Greenberg AH (1992) A natural killer cell granule protein that induces DNA fragmentation and apoptosis. J Exp Med 175: 553
24. Stacey NH, Bishop CJ, Halliday JW, Halliday WJ, Cooksley WGE, Powell LW, Kerr JFR (1985) Apoptosis as the mode of cell death in antibody-dependent lymphocytotoxicity. J Cell Sci 74: 169
25. Steplewski Z, Lubeck MD, Koprowski H (1983) Human macrophages armed with murine immunoglobulin G2a antibodies to tumors destroy human cancer cells. Science 221: 865
26. Szefler SJ, Norton CE, Ball B, Gross JM, Aida Y, Pabst MJ (1989) IFN-γ and LPS overcome glucocorticoid inhibition of priming for superoxide release in human monocytes. Evidence that secretion of IL-1 and tumor necrosis factor-α is not essential for monocyte priming. J Immunol 142: 3985
27. Takamuku K, Akiyoshi T, Tsuji H (1987) Antibody-dependent cell-mediated cytotoxicity using a murine monoclonal antibody against human colorectal cancer in cancer patients. Cancer Immunol Immunother 25: 137
28. Loosdrecht AA van de, Ossenkoppele GJ, Beelen RHJ, Broekhoven MG, Drager AM, Langenhuijsen MMAC (1993) Apoptosis in tumor necrosis factor-α-dependent, monocyte-mediated, leukemic cell death: a functional, morphologic, and flow-cytometric analysis. Exp Hematol 21: 1628
29. Weiner LM, Moldofsky PJ, Gatenby RA, O'Dwyer J, O'Brien J, Litwin S, Comis RL (1988) Antibody delivery and effector cell activation in a phase II trial of recombinant γ-interferon and the murine monoclonal antibody CO17-1A in advanced colorectal carcinoma. Cancer Res 48: 2568
30. Weiner LM, Steplewski Z, Koprowski H, Litwin S, Comis RT (1988) Divergent dose-related effects of γ-interferon therapy on in vitro antibody-dependent cellular and nonspecific cytotoxicity by human peripheral blood monocytes. Cancer Res 48: 1042
31. Zychlinsky A, Zheng LM, Liu C-C, Young JD-E (1991) Cytolytic lymphocytes induce both apoptosis and necrosis in target cells. J Immunol 146: 393