메뉴 건너뛰기




Volumn 213, Issue 3, 1996, Pages 238-247

Interleukin-6-type cytokines in vivo: Regulated bioavailability

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE; INTERLEUKIN 6; INTERLEUKIN 6 RECEPTOR; NEUTRALIZING ANTIBODY;

EID: 0030463760     PISSN: 00379727     EISSN: None     Source Type: Journal    
DOI: 10.3181/00379727-213-44055     Document Type: Review
Times cited : (27)

References (73)
  • 1
    • 0024530685 scopus 로고
    • Regulation of the acute phase and immune responses: Interleukin-6
    • Sehgal PB, Tosato G, Grieninger G, Eds.
    • Sehgal PB, Tosato G, Grieninger G, Eds. Regulation of the acute phase and immune responses: interleukin-6. Ann NY Acad Sci 557:1-583, 1989.
    • (1989) Ann NY Acad Sci , vol.557 , pp. 1-583
  • 2
    • 0025260903 scopus 로고
    • Interleukin-6: An overview
    • Van Snick J. Interleukin-6: An overview. Annu Rev Immunol 8:253-278, 1990.
    • (1990) Annu Rev Immunol , vol.8 , pp. 253-278
    • Van Snick, J.1
  • 3
    • 0029084805 scopus 로고
    • Interleukin-6 family of cytokines and gp130
    • Kishimoto T, Akira S, Narazaki M, Taga T. Interleukin-6 family of cytokines and gp130. Blood 86:1243-1254, 1995.
    • (1995) Blood , vol.86 , pp. 1243-1254
    • Kishimoto, T.1    Akira, S.2    Narazaki, M.3    Taga, T.4
  • 4
    • 0029091538 scopus 로고
    • Interleukin-6-type cytokines
    • Mackiewicz A, Koj A, Sehgal PB, Eds.
    • Mackiewicz A, Koj A, Sehgal PB, Eds. Interleukin-6-type cytokines. Ann NY Acad Sci 762:1-513, 1995.
    • (1995) Ann NY Acad Sci , vol.762 , pp. 1-513
  • 5
    • 0027240729 scopus 로고
    • Antibodies chaperone circulating IL-6: Paradoxical effects of anti-IL-6 "neutralizing" antibodies in vivo
    • May LT, Neta R, Moldawer LL, Kenney JS, Patel K, Sehgal PB. Antibodies chaperone circulating IL-6: Paradoxical effects of anti-IL-6 "neutralizing" antibodies in vivo. J Immunol 151: 3225-3236, 1993.
    • (1993) J Immunol , vol.151 , pp. 3225-3236
    • May, L.T.1    Neta, R.2    Moldawer, L.L.3    Kenney, J.S.4    Patel, K.5    Sehgal, P.B.6
  • 6
    • 0027239843 scopus 로고
    • Anti-cytokine antibodies as carrier proteins: Prolongation of in vivo effects of exogenous cytokines by injection of cytokine-anti-cytokine antibody complexes
    • Finkelman FD, Madden KB, Morris SC, Holmes JM, Boiani N, Katona IM, Maliszeski CR. Anti-cytokine antibodies as carrier proteins: prolongation of in vivo effects of exogenous cytokines by injection of cytokine-anti-cytokine antibody complexes. J Immunol 151:1235-1244, 1993.
    • (1993) J Immunol , vol.151 , pp. 1235-1244
    • Finkelman, F.D.1    Madden, K.B.2    Morris, S.C.3    Holmes, J.M.4    Boiani, N.5    Katona, I.M.6    Maliszeski, C.R.7
  • 7
    • 0026475047 scopus 로고
    • High amounts of circulating interleukin (IL)-6 in the form of monomeric immune complexes during anti-IL-6 therapy. Towards a new methodology for measuring overall cytokine production in human in vivo
    • Lu ZV, Brochier J, Wijdenes J, Brailly H, Bataille R, Klein B. High amounts of circulating interleukin (IL)-6 in the form of monomeric immune complexes during anti-IL-6 therapy. Towards a new methodology for measuring overall cytokine production in human in vivo. Eur J Immunol 22:2819-2824, 1992.
    • (1992) Eur J Immunol , vol.22 , pp. 2819-2824
    • Lu, Z.V.1    Brochier, J.2    Wijdenes, J.3    Brailly, H.4    Bataille, R.5    Klein, B.6
  • 15
    • 0027293104 scopus 로고
    • Soluble forms of the interleukin-6 signal-transducing receptor component gp130 in human serum possessing a potential to inhibit signals through membrane-anchored gp130
    • Narazaki M, Yasukawa K, Saito T, Ohsugi Y, Fukui H, Koishihara Y, Yancopoulos GD, Taga T, Kishimoto T. Soluble forms of the interleukin-6 signal-transducing receptor component gp130 in human serum possessing a potential to inhibit signals through membrane-anchored gp130. Blood 82:1120-1126, 1993.
    • (1993) Blood , vol.82 , pp. 1120-1126
    • Narazaki, M.1    Yasukawa, K.2    Saito, T.3    Ohsugi, Y.4    Fukui, H.5    Koishihara, Y.6    Yancopoulos, G.D.7    Taga, T.8    Kishimoto, T.9
  • 17
    • 0019201817 scopus 로고
    • Heterogeneity of poly(I)poly(C)-induced human fibroblast interferon mRNA species
    • Sehgal PB, Sagar AD. Heterogeneity of poly(I)poly(C)-induced human fibroblast interferon mRNA species. Nature 287:95-97, 1980.
    • (1980) Nature , vol.287 , pp. 95-97
    • Sehgal, P.B.1    Sagar, A.D.2
  • 18
    • 0023432812 scopus 로고
    • 2/B-cell stimulatory factor type 2 shares identity with monocyte-derived hepatocyte stimulating factor and regulates the major acute phase protein response in liver cells
    • 2/B-cell stimulatory factor type 2 shares identity with monocyte-derived hepatocyte stimulating factor and regulates the major acute phase protein response in liver cells. Proc Natl Acad Sci USA 84:7251-7255, 1987.
    • (1987) Proc Natl Acad Sci USA , vol.84 , pp. 7251-7255
    • Gauldie, J.1    Richards, C.2    Harnish, D.3    Lansdorp, P.4    Baumann, H.5
  • 19
    • 0020645330 scopus 로고
    • Hepatocyte stimulating factor: A monocyte-derived acute phase regulatory protein
    • Ritchie DG, Fuller GM. Hepatocyte stimulating factor: a monocyte-derived acute phase regulatory protein. Ann NY Acad Sci 408:490-502, 1983.
    • (1983) Ann NY Acad Sci , vol.408 , pp. 490-502
    • Ritchie, D.G.1    Fuller, G.M.2
  • 20
    • 0001017694 scopus 로고
    • Regulation of fibrinogen synthesis by plasmin-derived fragments of fribinogen and fibrin: An indirect feedback pathway
    • Ritchie DG, Levy BA, Adams MA, Fuller GM. Regulation of fibrinogen synthesis by plasmin-derived fragments of fribinogen and fibrin: An indirect feedback pathway. Proc Natl Acad Sci USA 79:175-179, 1982.
    • (1982) Proc Natl Acad Sci USA , vol.79 , pp. 175-179
    • Ritchie, D.G.1    Levy, B.A.2    Adams, M.A.3    Fuller, G.M.4
  • 23
    • 0001570486 scopus 로고
    • A growth factor for B-cell hybridomas produced by human monocytes
    • Aarden LA, Lansdorp PM, de Groot ER. A growth factor for B-cell hybridomas produced by human monocytes. Lymphokines 10:175-185, 1985.
    • (1985) Lymphokines , vol.10 , pp. 175-185
    • Aarden, L.A.1    Lansdorp, P.M.2    De Groot, E.R.3
  • 24
    • 0022521830 scopus 로고
    • A macrophage-derived factor required by plasmacytomas for survival and proliferation in vitro
    • Nordan R, Potter M. A macrophage-derived factor required by plasmacytomas for survival and proliferation in vitro. Science 233:566-569, 1986.
    • (1986) Science , vol.233 , pp. 566-569
    • Nordan, R.1    Potter, M.2
  • 25
    • 0023928315 scopus 로고
    • Identification of a 24-kDa cytokine that is required for development of cytolytic T-lymphocytes
    • Cernetti C, Steinman RM, Piperno-Granelli A. Identification of a 24-kDa cytokine that is required for development of cytolytic T-lymphocytes. Proc Natl Acad Sci USA 85:1605-1609, 1988.
    • (1988) Proc Natl Acad Sci USA , vol.85 , pp. 1605-1609
    • Cernetti, C.1    Steinman, R.M.2    Piperno-Granelli, A.3
  • 26
    • 0023847979 scopus 로고
    • B cell stimulatory factor 2 is involved in the differentiation of cytotoxtic T lymphocytes
    • Takai Y, Wong GG, Clark SC, Burakoff SJ, Hermann SH. B cell stimulatory factor 2 is involved in the differentiation of cytotoxtic T lymphocytes. J Immunol 140:508-512, 1988.
    • (1988) J Immunol , vol.140 , pp. 508-512
    • Takai, Y.1    Wong, G.G.2    Clark, S.C.3    Burakoff, S.J.4    Hermann, S.H.5
  • 27
    • 0001301728 scopus 로고
    • 2 interferon) functions as a second signal for interleukin-2 production by mature murine T cells
    • 2 interferon) functions as a second signal for interleukin-2 production by mature murine T cells. Proc Natl Acad Sci USA 84:7629-7633, 1987.
    • (1987) Proc Natl Acad Sci USA , vol.84 , pp. 7629-7633
    • Garman, R.D.1    Jacobs, K.A.2    Clark, S.C.3    Raulet, D.H.4
  • 32
    • 0024358854 scopus 로고
    • Interleukin-6 decreases cell-cell association and increases motility of ductal breast carcinoma cells
    • Tamm I, Cardinale I, Krueger J, Murphy JS, May LT, Sehgal PB. Interleukin-6 decreases cell-cell association and increases motility of ductal breast carcinoma cells. J Exp Med 170:1649-1669, 1989.
    • (1989) J Exp Med , vol.170 , pp. 1649-1669
    • Tamm, I.1    Cardinale, I.2    Krueger, J.3    Murphy, J.S.4    May, L.T.5    Sehgal, P.B.6
  • 33
    • 0024334846 scopus 로고
    • 1-antitrypsin in human mononuclear phagocytes and in human hepatoma lines
    • 1-antitrypsin in human mononuclear phagocytes and in human hepatoma lines. J Clin Invest 84:138-144, 1989.
    • (1989) J Clin Invest , vol.84 , pp. 138-144
    • Perlmutter, D.H.1    May, L.T.2    Sehgal, P.B.3
  • 34
    • 0024346018 scopus 로고
    • 2 (Interleukin-6) stimulates synthesis of complement proteins factor B and C3 in human skin fibroblasts
    • 2 (Interleukin-6) stimulates synthesis of complement proteins factor B and C3 in human skin fibroblasts. Eur J Immunol 19:983-988, 1989.
    • (1989) Eur J Immunol , vol.19 , pp. 983-988
    • Katz, Y.1    Revel, M.2    Strunk, R.C.3
  • 35
    • 0343163257 scopus 로고
    • Interleukin-6 enhancement of interleukin-3-dependent proliferation of multipotential hemopoietic progenitors
    • Ikebuchi K, Wong GG, Clark SC, Ihle JN, Hirai Y, Ogawa M. Interleukin-6 enhancement of interleukin-3-dependent proliferation of multipotential hemopoietic progenitors. Proc Natl Acad Sci USA 84:9035-9039, 1987.
    • (1987) Proc Natl Acad Sci USA , vol.84 , pp. 9035-9039
    • Ikebuchi, K.1    Wong, G.G.2    Clark, S.C.3    Ihle, J.N.4    Hirai, Y.5    Ogawa, M.6
  • 36
    • 0023691651 scopus 로고
    • Induction of neuronal differentiation in PC12 cells by B-cell stimulatory factor 2/Interleukin-6
    • Satoh T, Nakamura S, Taga T, Matsuda T, Hirano T, Kishimoto T, Kaziro Y. Induction of neuronal differentiation in PC12 cells by B-cell stimulatory factor 2/Interleukin-6. Mol Cell Biol 8:3546-3549, 1988.
    • (1988) Mol Cell Biol , vol.8 , pp. 3546-3549
    • Satoh, T.1    Nakamura, S.2    Taga, T.3    Matsuda, T.4    Hirano, T.5    Kishimoto, T.6    Kaziro, Y.7
  • 40
    • 0022447204 scopus 로고
    • Structure analysis of the sequence coding for an inducible 26 kDa protein in human fibroblasts
    • Haegeman C, Content J, Volckaert G, Derynck R, Tavernier J, Fiers W. Structure analysis of the sequence coding for an inducible 26 kDa protein in human fibroblasts. Eur J Biochem 159:625-632, 1986.
    • (1986) Eur J Biochem , vol.159 , pp. 625-632
    • Haegeman, C.1    Content, J.2    Volckaert, G.3    Derynck, R.4    Tavernier, J.5    Fiers, W.6
  • 44
    • 0026166625 scopus 로고
    • Marked cell-type-specific differences in glycosylation of human interleukin-6
    • May LT, Shaw JE, Khanna AK, Zabriskie JB, Sehgal PB. Marked cell-type-specific differences in glycosylation of human interleukin-6. Cytokine 3:204-211, 1991.
    • (1991) Cytokine , vol.3 , pp. 204-211
    • May, L.T.1    Shaw, J.E.2    Khanna, A.K.3    Zabriskie, J.B.4    Sehgal, P.B.5
  • 46
    • 0347333807 scopus 로고
    • 2 interferon/hepatocyte stimulating factor/IL-6 promoter by cytokines, viruses and second messenger agonists
    • 2 interferon/hepatocyte stimulating factor/IL-6 promoter by cytokines, viruses and second messenger agonists. Proc Natl Acad Sci USA 85:6701-6705, 1988.
    • (1988) Proc Natl Acad Sci USA , vol.85 , pp. 6701-6705
    • Ray, A.1    Tatter, S.B.2    May, L.T.3    Sehgal, P.B.4
  • 47
    • 0024355425 scopus 로고
    • A mulliple cytokine- And second-messenger-responsive element in the enhancer of the human interleukin-6 gene: Similarities with c-fos gene regulation
    • Ray A, Sassone-Corsi P, Sehgal PB. A mulliple cytokine- and second-messenger-responsive element in the enhancer of the human interleukin-6 gene: Similarities with c-fos gene regulation. Mol Cell Biol 9:5537-5547, 1989.
    • (1989) Mol Cell Biol , vol.9 , pp. 5537-5547
    • Ray, A.1    Sassone-Corsi, P.2    Sehgal, P.B.3
  • 49
    • 0025047444 scopus 로고
    • On the mechanism for efficient repression of the interleukin-6 promoter by glucocorticoids: Enhancer, TATA box, and RNA start site (Inr motif) occlusion
    • Ray A, LaForge KS, Sehgal PB. On the mechanism for efficient repression of the interleukin-6 promoter by glucocorticoids: Enhancer, TATA box, and RNA start site (Inr motif) occlusion. Mol Cell Biol 10:5736-5746, 1990.
    • (1990) Mol Cell Biol , vol.10 , pp. 5736-5746
    • Ray, A.1    LaForge, K.S.2    Sehgal, P.B.3
  • 50
    • 0025775929 scopus 로고
    • Repression of the interleukin-6 promoter by p53 and the retinoblastoma susceptibility gene product
    • Santhanam U, Ray A, Sehgal PB. Repression of the interleukin-6 promoter by p53 and the retinoblastoma susceptibility gene product. Proc Natl Acad Sci USA 88:7605-7609, 1991.
    • (1991) Proc Natl Acad Sci USA , vol.88 , pp. 7605-7609
    • Santhanam, U.1    Ray, A.2    Sehgal, P.B.3
  • 51
    • 0027244682 scopus 로고
    • Modulation of the human interleukin-6 (IL-6) promoter and transcription factor C/EBPβ (NF-IL6) activity by p53 species
    • Margulies L, Sehgal PB. Modulation of the human interleukin-6 (IL-6) promoter and transcription factor C/EBPβ (NF-IL6) activity by p53 species. J Biol Chem 268:15096-15100, 1993.
    • (1993) J Biol Chem , vol.268 , pp. 15096-15100
    • Margulies, L.1    Sehgal, P.B.2
  • 52
    • 0027385039 scopus 로고
    • Cell-type and promoter-dependent ts phenotype of p53 Val-135
    • Sehgal PB, Margulies L. Cell-type and promoter-dependent ts phenotype of p53 Val-135. Oncogene 8:3417-3419, 1993.
    • (1993) Oncogene , vol.8 , pp. 3417-3419
    • Sehgal, P.B.1    Margulies, L.2
  • 53
    • 0028107237 scopus 로고
    • Physical association and functional antagonism between the p65 subunit of transcription factor NF-κB and the glucocorticoid receptor
    • Ray A, Prefontaine KE. Physical association and functional antagonism between the p65 subunit of transcription factor NF-κB and the glucocorticoid receptor. Proc Natl Acad Sci USA 91:752-756, 1994.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 752-756
    • Ray, A.1    Prefontaine, K.E.2
  • 54
    • 0029115441 scopus 로고
    • Regulation of interleukin-6 gene expression by steroids
    • Ray A, Zhang DH, Siegel MD, Ray P. Regulation of interleukin-6 gene expression by steroids. Ann NY Acad Sci 762:79-88, 1995.
    • (1995) Ann NY Acad Sci , vol.762 , pp. 79-88
    • Ray, A.1    Zhang, D.H.2    Siegel, M.D.3    Ray, P.4
  • 55
    • 0028222533 scopus 로고
    • Down-modulation of interleukin-6 gene expression by 17β-estradiol in the absence of high affinity DNA binding by the estrogen receptor
    • Ray A, Prefontaine KE, Ray P. Down-modulation of interleukin-6 gene expression by 17β-estradiol in the absence of high affinity DNA binding by the estrogen receptor. J Biol Chem 259:12940-12946, 1994.
    • (1994) J Biol Chem , vol.259 , pp. 12940-12946
    • Ray, A.1    Prefontaine, K.E.2    Ray, P.3
  • 56
    • 0029147741 scopus 로고
    • Repression of the interleukin-6 promoter by estrogen receptor is mediated by NF-κB and C/EBPβ
    • Stein B, Yang MX. Repression of the interleukin-6 promoter by estrogen receptor is mediated by NF-κB and C/EBPβ. Mol Cell Biol 15:4971-1979, 1995.
    • (1995) Mol Cell Biol , vol.15 , pp. 4971-11979
    • Stein, B.1    Yang, M.X.2
  • 58
  • 59
    • 0024458160 scopus 로고
    • Soluble cytokine receptors are present in normal human urine
    • Novick D, Engelman H, Wallach D, Rubinstein M. Soluble cytokine receptors are present in normal human urine. J Exp Med 170:1409-1414, 1989.
    • (1989) J Exp Med , vol.170 , pp. 1409-1414
    • Novick, D.1    Engelman, H.2    Wallach, D.3    Rubinstein, M.4
  • 61
    • 0026782577 scopus 로고
    • The complex of soluble human interleukin-6 receptor/interleukin-6 upregulates expression of acute phase proteins
    • Mackiewicz A, Schooltink H, Heinrich PC, Rose-John S. The complex of soluble human interleukin-6 receptor/interleukin-6 upregulates expression of acute phase proteins. J Immunol 149:2021-2027, 1992.
    • (1992) J Immunol , vol.149 , pp. 2021-2027
    • Mackiewicz, A.1    Schooltink, H.2    Heinrich, P.C.3    Rose-John, S.4
  • 63
    • 0029115697 scopus 로고
    • Signal transduction through IL-6 receptor: Involvement of multiple protein kinases, stat Factors, and a novel H7-sensitive pathway
    • Nakajima K, Matsuda T, Fujitani Y, Kojima H, Yamanaka Y, Nakae K, Takeda T, Hirano T. Signal transduction through IL-6 receptor: Involvement of multiple protein kinases, stat Factors, and a novel H7-sensitive pathway. Ann NY Acad Sci 762:55-70, 1995.
    • (1995) Ann NY Acad Sci , vol.762 , pp. 55-70
    • Nakajima, K.1    Matsuda, T.2    Fujitani, Y.3    Kojima, H.4    Yamanaka, Y.5    Nakae, K.6    Takeda, T.7    Hirano, T.8
  • 65
    • 0026673488 scopus 로고
    • Protective effect of anti-IL-6 antibody against endotoxin, associated with paradoxically increased IL-6 levels
    • Heremans H, Dillen C, Put W, Van Damme J, Billiau A. Protective effect of anti-IL-6 antibody against endotoxin, associated with paradoxically increased IL-6 levels. Eur J Immunol 22:2395-2400, 1992.
    • (1992) Eur J Immunol , vol.22 , pp. 2395-2400
    • Heremans, H.1    Dillen, C.2    Put, W.3    Van Damme, J.4    Billiau, A.5
  • 66
    • 0025990893 scopus 로고
    • Murine anti-interleukin-6 monoclonal antibody therapy for a patient with plasma cell leukemia
    • Klein B, Wijdenes J, Zhang X-G. Murine anti-interleukin-6 monoclonal antibody therapy for a patient with plasma cell leukemia. Blood 78:1198-1204, 1991.
    • (1991) Blood , vol.78 , pp. 1198-1204
    • Klein, B.1    Wijdenes, J.2    Zhang, X.-G.3
  • 71
    • 0027463210 scopus 로고
    • High affinity IgG autoantibodies to IL-6 in sera of normal individuals are competitive inhibitors of IL-6 in vitro
    • Hansen MB, Svenson M, Diamant M, Bendtzen K. High affinity IgG autoantibodies to IL-6 in sera of normal individuals are competitive inhibitors of IL-6 in vitro. Cytokine 5:72-80, 1993.
    • (1993) Cytokine , vol.5 , pp. 72-80
    • Hansen, M.B.1    Svenson, M.2    Diamant, M.3    Bendtzen, K.4
  • 72
    • 0028345082 scopus 로고
    • Serum soluble interleukin 6 (IL-6) receptor and IL-6/ soluble IL-6 receptor complex in systemic juvenile rheumatoid arthritis
    • DeBenedetti F, Massa M, Pignatti P, Albani S, Novick D, Martini A. Serum soluble interleukin 6 (IL-6) receptor and IL-6/ soluble IL-6 receptor complex in systemic juvenile rheumatoid arthritis. J Clin Invest 93:2114-2119, 1994.
    • (1994) J Clin Invest , vol.93 , pp. 2114-2119
    • DeBenedetti, F.1    Massa, M.2    Pignatti, P.3    Albani, S.4    Novick, D.5    Martini, A.6
  • 73
    • 2842593409 scopus 로고    scopus 로고
    • Sustained high levels of circulating interleukin-6 in patients subjected to active anti-cancer immunization protocols: Anti-IL-6 and anti-sIL-6R IgG
    • Ndubuisi M, Patel K, May LT, Mittelman A, Sehgal PB. Sustained high levels of circulating interleukin-6 in patients subjected to active anti-cancer immunization protocols: Anti-IL-6 and anti-sIL-6R IgG. (abstract) Ann Meeting, Am Assoc Imm, 1996.
    • (1996) Ann Meeting, Am Assoc Imm
    • Ndubuisi, M.1    Patel, K.2    May, L.T.3    Mittelman, A.4    Sehgal, P.B.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.