메뉴 건너뛰기




Volumn 62, Issue 11, 1996, Pages 1543-1549

Tolerance in a rat cardiac allograft model after short-term treatment with LF 08-0299. Absence of clonal deletion and evidence of CD4+ suppressor cells

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIGEN; IMMUNOSUPPRESSIVE AGENT; LF 080299; UNCLASSIFIED DRUG;

EID: 0030463216     PISSN: 00411337     EISSN: None     Source Type: Journal    
DOI: 10.1097/00007890-199612150-00003     Document Type: Article
Times cited : (21)

References (47)
  • 1
    • 0027474142 scopus 로고
    • The immunobiology clinical use of current immunosuppressive therapy for renal transplantation
    • Hayes JM. The immunobiology clinical use of current immunosuppressive therapy for renal transplantation. J Urol 1993; 149: 437.
    • (1993) J Urol , vol.149 , pp. 437
    • Hayes, J.M.1
  • 2
    • 0026579147 scopus 로고
    • Specific acceptance of cardiac allograft after treatment with antibodies to ICAM-1 and LFA-1
    • Isobe M, Yagita H, Okumura K, Ihara A. Specific acceptance of cardiac allograft after treatment with antibodies to ICAM-1 and LFA-1. Science 1992; 255: 1125.
    • (1992) Science , vol.255 , pp. 1125
    • Isobe, M.1    Yagita, H.2    Okumura, K.3    Ihara, A.4
  • 4
    • 0028026941 scopus 로고
    • Rapamycin inhibits production of cytotoxic but not noncytotoxic antibodies and preferentially activates T helper 2 cells that mediate long-term survival of heart allografts in rats
    • Ferraresso M, Tian L, Ghobrial R, Stepkowski SM, Kahan BD. Rapamycin inhibits production of cytotoxic but not noncytotoxic antibodies and preferentially activates T helper 2 cells that mediate long-term survival of heart allografts in rats. J Immunol 1994; 153: 3307.
    • (1994) J Immunol , vol.153 , pp. 3307
    • Ferraresso, M.1    Tian, L.2    Ghobrial, R.3    Stepkowski, S.M.4    Kahan, B.D.5
  • 5
    • 0024230983 scopus 로고
    • 31P nuclear magnetic resonance spectrography, and its effect on rat heart transplantation
    • 31P nuclear magnetic resonance spectrography, and its effect on rat heart transplantation. Transplantation 1988; 46: 669.
    • (1988) Transplantation , vol.46 , pp. 669
    • Suzuki, S.1    Kanashiro, M.2    Watanabe, H.3    Amemiya, H.4
  • 6
    • 0027419726 scopus 로고
    • Brequinar sodium suppresses liver allograft rejection and induces permanent tolerance in the rat
    • Knoop M, Cramer DV, Chapman FC, Makowka L. Brequinar sodium suppresses liver allograft rejection and induces permanent tolerance in the rat. Transplant Proc 1993; 25: 706.
    • (1993) Transplant Proc , vol.25 , pp. 706
    • Knoop, M.1    Cramer, D.V.2    Chapman, F.C.3    Makowka, L.4
  • 7
    • 0023568088 scopus 로고
    • Studies of the induction and maintenance of long-term graft acceptance by treatment with FK506 in heterotopic cardiac allotransplantation in rats
    • Ochiai T, Nakajima K, Nagata M, Hori S, Asano T, Isono K. Studies of the induction and maintenance of long-term graft acceptance by treatment with FK506 in heterotopic cardiac allotransplantation in rats. Transplantation 1987; 44: 734.
    • (1987) Transplantation , vol.44 , pp. 734
    • Ochiai, T.1    Nakajima, K.2    Nagata, M.3    Hori, S.4    Asano, T.5    Isono, K.6
  • 8
    • 0028569059 scopus 로고
    • Immunosuppressive drugs and the induction of transplantation tolerance
    • Thomson AW. Immunosuppressive drugs and the induction of transplantation tolerance. Transplant Immunol 1994; 2: 263.
    • (1994) Transplant Immunol , vol.2 , pp. 263
    • Thomson, A.W.1
  • 9
    • 0023138045 scopus 로고
    • Specific cytotoxic T cells are found in the nonrejected kidneys of blood-transfused rats
    • Dallman MJ, Wood KJ, Morris PJ. Specific cytotoxic T cells are found in the nonrejected kidneys of blood-transfused rats. J Exp Med 1987; 165: 566.
    • (1987) J Exp Med , vol.165 , pp. 566
    • Dallman, M.J.1    Wood, K.J.2    Morris, P.J.3
  • 10
    • 0026633744 scopus 로고
    • Induction of stable chimerism and transplantation tolerance to rat islet and heart allografts by ultraviolet-B modulation of bone marrow cells
    • Jin MX, Engelstad K, Oluwole SF. Induction of stable chimerism and transplantation tolerance to rat islet and heart allografts by ultraviolet-B modulation of bone marrow cells. Transplantation 1992; 54: 113.
    • (1992) Transplantation , vol.54 , pp. 113
    • Jin, M.X.1    Engelstad, K.2    Oluwole, S.F.3
  • 12
    • 23444459237 scopus 로고
    • Tolerance to an HLA-B,DR disparate kidney allograft after bone-marrow transplantation from same donor
    • Jacobsen N, Taaning E, Ladefoged J, Kristensen JK, Pedersen FK. Tolerance to an HLA-B,DR disparate kidney allograft after bone-marrow transplantation from same donor. Lancet 1994; 343: 800.
    • (1994) Lancet , vol.343 , pp. 800
    • Jacobsen, N.1    Taaning, E.2    Ladefoged, J.3    Kristensen, J.K.4    Pedersen, F.K.5
  • 13
    • 0026785294 scopus 로고
    • Induction of specific tolerance to class I-disparate renal allografts in miniature swine with cyclosporine
    • Rosengard Br, Ojikutu CA, Guzzetta PC, et al. Induction of specific tolerance to class I-disparate renal allografts in miniature swine with cyclosporine. Transplantation 1992; 54: 490.
    • (1992) Transplantation , vol.54 , pp. 490
    • Rosengard, Br.1    Ojikutu, C.A.2    Guzzetta, P.C.3
  • 14
    • 0028205855 scopus 로고
    • Development of tolerance to class II-mismatched renal transplants after a short course of cyclosporine therapy in miniature swine
    • Fishbein JM, Rosengard Br, Gianello P, et al. Development of tolerance to class II-mismatched renal transplants after a short course of cyclosporine therapy in miniature swine. Transplantation 1994; 57: 1303.
    • (1994) Transplantation , vol.57 , pp. 1303
    • Fishbein, J.M.1    Rosengard, Br.2    Gianello, P.3
  • 15
    • 0028123516 scopus 로고
    • Further studies of veto activity in rhesus monkey bone marrow in relation to allograft tolerance and chimerism
    • Thomas JM, Carver FM, Kasten-Jolly J, et al. Further studies of veto activity in rhesus monkey bone marrow in relation to allograft tolerance and chimerism. Transplantation 1994; 57: 101.
    • (1994) Transplantation , vol.57 , pp. 101
    • Thomas, J.M.1    Carver, F.M.2    Kasten-Jolly, J.3
  • 16
    • 0029552642 scopus 로고
    • LF 08-0299 protects murine recipients of minor antigen disparate donor marrow from lethal graft-versus-host disease
    • Bruley-Rosset M, Churaqui E, Annat J, Dutartre P. LF 08-0299 protects murine recipients of minor antigen disparate donor marrow from lethal graft-versus-host disease. Ann N Y Acad Sci 1995; 770: 373.
    • (1995) Ann N Y Acad Sci , vol.770 , pp. 373
    • Bruley-Rosset, M.1    Churaqui, E.2    Annat, J.3    Dutartre, P.4
  • 17
    • 0029780353 scopus 로고    scopus 로고
    • Prevention of lethal graft-versus-host disease following allogeneic bone marrow transplantation in mice by short course administration of LF 08-0299
    • Annat J, Churaqui E, Dutartre P, Bruley-Rosset M. Prevention of lethal graft-versus-host disease following allogeneic bone marrow transplantation in mice by short course administration of LF 08-0299. Transplantation 1996; 62(6): 721.
    • (1996) Transplantation , vol.62 , Issue.6 , pp. 721
    • Annat, J.1    Churaqui, E.2    Dutartre, P.3    Bruley-Rosset, M.4
  • 18
    • 0028831347 scopus 로고
    • LF 08-0299 induces tolerance after short-term treatment in a fully major histocompatibility mismatched rat cardiac allograft model
    • Dutartre P, Annat J, Derrepas P. LF 08-0299 induces tolerance after short-term treatment in a fully major histocompatibility mismatched rat cardiac allograft model. Transplant Proc 1995; 27: 440.
    • (1995) Transplant Proc , vol.27 , pp. 440
    • Dutartre, P.1    Annat, J.2    Derrepas, P.3
  • 19
    • 0024385635 scopus 로고
    • Genetic control of rat heart allograft rejection: Effect of different MHC and non-MHC incompatibilities
    • Klempnauer J, Steiniger B, Lÿck R, Gÿnther E. Genetic control of rat heart allograft rejection: effect of different MHC and non-MHC incompatibilities. Immunogenetics 1989; 30: 81.
    • (1989) Immunogenetics , vol.30 , pp. 81
    • Klempnauer, J.1    Steiniger, B.2    Lÿck, R.3    Gÿnther, E.4
  • 20
    • 0025946532 scopus 로고
    • Factors determining prolongation of rat heart allograft survival by perioperative injection of donor spleen cells
    • Westra AL, Petersen AH, Wildevuur CRH, Prop P. Factors determining prolongation of rat heart allograft survival by perioperative injection of donor spleen cells. Transplantation 1991; 52: 606.
    • (1991) Transplantation , vol.52 , pp. 606
    • Westra, A.L.1    Petersen, A.H.2    Wildevuur, C.R.H.3    Prop, P.4
  • 21
    • 0014468579 scopus 로고
    • Improved technique of heart transplantation in rats
    • Ono K, Lindsey ES. Improved technique of heart transplantation in rats. J Thorac Cardiovasc Surg 1969; 57: 225.
    • (1969) J Thorac Cardiovasc Surg , vol.57 , pp. 225
    • Ono, K.1    Lindsey, E.S.2
  • 23
    • 0019468220 scopus 로고
    • Limiting dilution assays for the determination of immunocompetent cell frequencies
    • Taswell C. Limiting dilution assays for the determination of immunocompetent cell frequencies. J Immunol 1981; 126: 1614.
    • (1981) J Immunol , vol.126 , pp. 1614
    • Taswell, C.1
  • 26
    • 0018871999 scopus 로고
    • Graft adaptation: Studies on possible mechanisms in long-surviving rat renal allografts
    • Hart DNJ, Winearls CG, Fabre JW. Graft adaptation: studies on possible mechanisms in long-surviving rat renal allografts. Transplantation 1980; 30: 73.
    • (1980) Transplantation , vol.30 , pp. 73
    • Hart, D.N.J.1    Winearls, C.G.2    Fabre, J.W.3
  • 27
    • 0020541402 scopus 로고
    • Mechanisms of reduced immunogenicity of retransplanted rat kidney allografts
    • Lechler RI, Batchelor JR. Mechanisms of reduced immunogenicity of retransplanted rat kidney allografts. Transplant Proc 1983; 15: 316.
    • (1983) Transplant Proc , vol.15 , pp. 316
    • Lechler, R.I.1    Batchelor, J.R.2
  • 28
    • 0025309472 scopus 로고
    • Clonal deletion versus clonal anergy: The role of the thymus in inducing self tolerance
    • Ramsdell F, Fowlkes BJ. Clonal deletion versus clonal anergy: the role of the thymus in inducing self tolerance. Science 1990; 248: 1342.
    • (1990) Science , vol.248 , pp. 1342
    • Ramsdell, F.1    Fowlkes, B.J.2
  • 29
    • 0025339511 scopus 로고
    • A cell culture model for T lymphocyte clonal anergy
    • Schwartz RH. A cell culture model for T lymphocyte clonal anergy. Science 1990; 248: 1349.
    • (1990) Science , vol.248 , pp. 1349
    • Schwartz, R.H.1
  • 30
    • 0027415419 scopus 로고
    • The mechanism of unresponsiveness to allografts induced by rapamycin and rapamycin/cyclosporine treatment in rats
    • Ferraresso M, Ghobrial R, Stepkowski SM, Kahan BD. The mechanism of unresponsiveness to allografts induced by rapamycin and rapamycin/cyclosporine treatment in rats. Transplantation 1993; 55: 888.
    • (1993) Transplantation , vol.55 , pp. 888
    • Ferraresso, M.1    Ghobrial, R.2    Stepkowski, S.M.3    Kahan, B.D.4
  • 31
    • 0024322929 scopus 로고
    • Alloreactive T suppressor cells in the rat. I. Evidence of three distinct subsets of splenic suppressor T cells resistant to cyclosporine
    • Rodrigues MAF, Hutchinson IV, Morris PJ. Alloreactive T suppressor cells in the rat. I. Evidence of three distinct subsets of splenic suppressor T cells resistant to cyclosporine. Transplantation 1989; 47: 847.
    • (1989) Transplantation , vol.47 , pp. 847
    • Rodrigues, M.A.F.1    Hutchinson, I.V.2    Morris, P.J.3
  • 32
    • 0026603775 scopus 로고
    • Revisiting and revising suppressor T cells
    • Bloom Br, Salgame P, Diamond B. Revisiting and revising suppressor T cells. Immunol Today 1992; 13: 131.
    • (1992) Immunol Today , vol.13 , pp. 131
    • Bloom, Br.1    Salgame, P.2    Diamond, B.3
  • 34
    • 0029049128 scopus 로고
    • In vivo studies of the maintenance of peripheral transplant tolerance after cyclosporine: Radiosensitive antigen-specific suppressor cells mediate lasting graft protection against primed effector cells
    • Nisco ST, Hissink RJ, Vriens PW, Hoyt EG, Reitz BA, Clayberger C. In vivo studies of the maintenance of peripheral transplant tolerance after cyclosporine: radiosensitive antigen-specific suppressor cells mediate lasting graft protection against primed effector cells. Transplantation 1995; 59: 1444.
    • (1995) Transplantation , vol.59 , pp. 1444
    • Nisco, S.T.1    Hissink, R.J.2    Vriens, P.W.3    Hoyt, E.G.4    Reitz, B.A.5    Clayberger, C.6
  • 35
    • 0027426785 scopus 로고
    • Examination of the mechanisms responsible for tolerance induction after intrathymic inoculation of allogeneic bone marrow
    • Odorico JS, O'Connor T, Campos L, Barker CF, Posselt Am, Naji A. Examination of the mechanisms responsible for tolerance induction after intrathymic inoculation of allogeneic bone marrow. Ann Surg 1993; 218: 525.
    • (1993) Ann Surg , vol.218 , pp. 525
    • Odorico, J.S.1    O'Connor, T.2    Campos, L.3    Barker, C.F.4    Posselt, Am.5    Naji, A.6
  • 36
    • 0027203672 scopus 로고
    • Similar levels of granzyme A and perform mRNA expression in rejected and tolerated heart allografts in donor-specific tolerance in rats
    • Bugeon L, Cuturi MC, Paineau J, Anegon I, Soulillou JP. Similar levels of granzyme A and perform mRNA expression in rejected and tolerated heart allografts in donor-specific tolerance in rats. Transplantation 1993; 56: 405.
    • (1993) Transplantation , vol.56 , pp. 405
    • Bugeon, L.1    Cuturi, M.C.2    Paineau, J.3    Anegon, I.4    Soulillou, J.P.5
  • 37
    • 0022448187 scopus 로고
    • Suppressor T cells in allogeneic models
    • Hutchinson IV. Suppressor T cells in allogeneic models. Transplantation 1986; 41: 547.
    • (1986) Transplantation , vol.41 , pp. 547
    • Hutchinson, I.V.1
  • 38
    • 0024605144 scopus 로고
    • Mediation of antigen-induced suppression of renal allograft rejection by a CD4 (W3/25+) T cell
    • Quigley RL, Wood KJ, Morris PJ. Mediation of antigen-induced suppression of renal allograft rejection by a CD4 (W3/25+) T cell. Transplantation 1989; 47: 684.
    • (1989) Transplantation , vol.47 , pp. 684
    • Quigley, R.L.1    Wood, K.J.2    Morris, P.J.3
  • 40
    • 0023269997 scopus 로고
    • Two phenotypically distinct populations of T cells have suppressor capabilities simultaneously in the maintenance phase of immunologic enhancement
    • Padberg WM, Lord RHH, Kupiec-Weglinski JW, et al. Two phenotypically distinct populations of T cells have suppressor capabilities simultaneously in the maintenance phase of immunologic enhancement. J Immunol 1987; 139: 1751.
    • (1987) J Immunol , vol.139 , pp. 1751
    • Padberg, W.M.1    Lord, R.H.H.2    Kupiec-Weglinski, J.W.3
  • 41
    • 0024356774 scopus 로고
    • Characteristics and func-tion of suppressor T lymphocytes in immunologically unresponsive rats following pretreatment with UV-B-irradiated donor leukocytes and peritransplant cyclosporine
    • Oluwole SF, Reemstma K, Hardy MA. Characteristics and func-tion of suppressor T lymphocytes in immunologically unresponsive rats following pretreatment with UV-B-irradiated donor leukocytes and peritransplant cyclosporine. Transplantation 1989; 47: 1001.
    • (1989) Transplantation , vol.47 , pp. 1001
    • Oluwole, S.F.1    Reemstma, K.2    Hardy, M.A.3
  • 42
    • 0026729563 scopus 로고
    • Heart allografts in murine systems: The differential activation of TH2-like effector cells in peripheral tolerance
    • Takeuchi T, Lowry RP, Konieczny B. Heart allografts in murine systems: the differential activation of TH2-like effector cells in peripheral tolerance. Transplantation 1992; 53: 1281.
    • (1992) Transplantation , vol.53 , pp. 1281
    • Takeuchi, T.1    Lowry, R.P.2    Konieczny, B.3
  • 43
    • 0027332312 scopus 로고
    • CD4 mAb therapy modulates alloantibody production and intracardiac graft deposition in association with selective inhibition of Th1 lymphokines
    • Kupiec-Weglinski JW, Wasowska B, Papp I, et al. CD4 mAb therapy modulates alloantibody production and intracardiac graft deposition in association with selective inhibition of Th1 lymphokines. J Immunol 1993; 151: 5053.
    • (1993) J Immunol , vol.151 , pp. 5053
    • Kupiec-Weglinski, J.W.1    Wasowska, B.2    Papp, I.3
  • 44
    • 0026666426 scopus 로고
    • Peripheral tolerance of an allograft in adult rats: Characterization by low interleukin-2 and Interferon-γ mRNA levels and by strong accumulation of major histocompatibility complex transcripts in the graft
    • Bugeon L, Cuturi MC, Hallet MM, Paineau J, Chabannes D, Soulillou JP. Peripheral tolerance of an allograft in adult rats: characterization by low interleukin-2 and Interferon-γ mRNA levels and by strong accumulation of major histocompatibility complex transcripts in the graft. Transplantation 1992; 54: 219.
    • (1992) Transplantation , vol.54 , pp. 219
    • Bugeon, L.1    Cuturi, M.C.2    Hallet, M.M.3    Paineau, J.4    Chabannes, D.5    Soulillou, J.P.6
  • 45
    • 0027340347 scopus 로고
    • Cytokines and peripheral tolerance to alloantigen
    • Dallman MJ, Wood KJ, Hamado K, et al. Cytokines and peripheral tolerance to alloantigen. Immunol Rev 1993; 133: 5.
    • (1993) Immunol Rev , vol.133 , pp. 5
    • Dallman, M.J.1    Wood, K.J.2    Hamado, K.3
  • 46
    • 0026027479 scopus 로고
    • Peripheral tolerance to alloantigen results from altered regulation of the interleukin 2 pathway
    • Dallman MJ, Shiho O, Page TH, Wood KJ, Morris PJ. Peripheral tolerance to alloantigen results from altered regulation of the interleukin 2 pathway. J Exp Med 1991; 173: 79.
    • (1991) J Exp Med , vol.173 , pp. 79
    • Dallman, M.J.1    Shiho, O.2    Page, T.H.3    Wood, K.J.4    Morris, P.J.5
  • 47
    • 0000930499 scopus 로고
    • The relationship of IL-4, IL-10 and other cytokines to transplantation tolerance
    • Lowry R. The relationship of IL-4, IL-10 and other cytokines to transplantation tolerance. Transplant Sci 1993; 3: 104.
    • (1993) Transplant Sci , vol.3 , pp. 104
    • Lowry, R.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.