메뉴 건너뛰기




Volumn 23, Issue 5-6, 1996, Pages 417-422

TP53 Mutations in myelodysplastic syndrome

Author keywords

Karyotype; Molecular epidemiology; Myelodysplastic syndrome; NRAS gene; p53 gene

Indexed keywords

CHROMOSOME 17; CHROMOSOME 5; CHROMOSOME 7; CHROMOSOME LOSS; GENE MUTATION; KARYOTYPE; MYELODYSPLASTIC SYNDROME; PRIORITY JOURNAL; REVIEW; TUMOR SUPPRESSOR GENE;

EID: 0030463176     PISSN: 10428194     EISSN: None     Source Type: Journal    
DOI: 10.3109/10428199609054848     Document Type: Review
Times cited : (29)

References (51)
  • 1
    • 0027234492 scopus 로고
    • A comparison of the biological activities of wild-type and mutant p53
    • Zambetti, G. P. and Levine, A. J. (1993) A comparison of the biological activities of wild-type and mutant p53. FASEB J., 7, 855-865.
    • (1993) FASEB J. , vol.7 , pp. 855-865
    • Zambetti, G.P.1    Levine, A.J.2
  • 3
    • 0026579237 scopus 로고
    • TP53 tumor suppressor gene: A model for investigating human mutagenesis
    • de Fromentel, C. C. and Soussi, T. (1992) TP53 tumor suppressor gene: a model for investigating human mutagenesis. Genes Chromo & Cancer, 4, 1-15.
    • (1992) Genes Chromo & Cancer , vol.4 , pp. 1-15
    • De Fromentel, C.C.1    Soussi, T.2
  • 4
    • 0028071555 scopus 로고
    • Mutations in the p53 tumor suppressor gene: Clues to cancer etiology and molecular pathosenesis
    • Greenblatt, M. S., Bennett, W. P., Hollstein, M. and Harris, C. C. (1994) Mutations in the p53 tumor suppressor gene: clues to cancer etiology and molecular pathosenesis. Cancer Res , 54, 4855-4878.
    • (1994) Cancer Res , vol.54 , pp. 4855-4878
    • Greenblatt, M.S.1    Bennett, W.P.2    Hollstein, M.3    Harris, C.C.4
  • 6
    • 0345560273 scopus 로고
    • Alterations in the p53 gene and the clonal evolution of the blast crisis of chronic myelocytic leukemia
    • Ahuja, H., Bar-Eli, M., Advani, S. H., Benchimol, S. and Cline, M. J. (1989) Alterations in the p53 gene and the clonal evolution of the blast crisis of chronic myelocytic leukemia. Proc. Natl. Acad. Sci. USA, 86, 6783-6787.
    • (1989) Proc. Natl. Acad. Sci. USA , vol.86 , pp. 6783-6787
    • Ahuja, H.1    Bar-Eli, M.2    Advani, S.H.3    Benchimol, S.4    Cline, M.J.5
  • 7
    • 0024435565 scopus 로고
    • Rearrangements in the p53 gene in Philadelphia chromosome positive chrome myelogenous leukemia
    • Kelman, Z., Prokocimer, M., Peller, S., Kahn, Y., Rechavi, G., Manor, Y., Cohen, A. and Rotter, V. (1989) Rearrangements in the p53 gene in Philadelphia chromosome positive chrome myelogenous leukemia. Blood, 74, 2318-2324.
    • (1989) Blood , vol.74 , pp. 2318-2324
    • Kelman, Z.1    Prokocimer, M.2    Peller, S.3    Kahn, Y.4    Rechavi, G.5    Manor, Y.6    Cohen, A.7    Rotter, V.8
  • 12
    • 0026693045 scopus 로고
    • Mutation of p53 gene does not play a critical role in myelodysplastic syndrome and its transformation to acute leukemia
    • Tsushita, K , Hotta, T., Ichikawa, A. and Saito, H. (1992) Mutation of p53 gene does not play a critical role in myelodysplastic syndrome and its transformation to acute leukemia. Br. J. Haematol., 82, 456-457.
    • (1992) Br. J. Haematol. , vol.82 , pp. 456-457
    • Tsushita, K.1    Hotta, T.2    Ichikawa, A.3    Saito, H.4
  • 13
    • 0027247412 scopus 로고
    • Mutations of the p53 gene in myelodysplastic syndrome (MDS) and MDS-derived leukemia
    • Sugimoto, K., Hirano, N., Toyoshima, H., Chiba, S., Mano, H., Takaku, F., Yazaki, Y. and Hirai, H. (1993) Mutations of the p53 gene in myelodysplastic syndrome (MDS) and MDS-derived leukemia. Blood, 81, 3022-3026.
    • (1993) Blood , vol.81 , pp. 3022-3026
    • Sugimoto, K.1    Hirano, N.2    Toyoshima, H.3    Chiba, S.4    Mano, H.5    Takaku, F.6    Yazaki, Y.7    Hirai, H.8
  • 14
    • 0028172868 scopus 로고
    • P53 mutations are associated with resistance to chemotherapy and short survival m hematologic malignancies
    • Wattel, E., Preudhomme, C., Hecquet, B , Vanrumbeke, M., Quesnel, B., Dervite, I., Morel, P. and Fenaux, P (1994) P53 mutations are associated with resistance to chemotherapy and short survival m hematologic malignancies. Blood, 84, 3148-3157.
    • (1994) Blood , vol.84 , pp. 3148-3157
    • Wattel, E.1    Preudhomme, C.2    Hecquet, B.3    Vanrumbeke, M.4    Quesnel, B.5    Dervite, I.6    Morel, P.7    Fenaux, P.8
  • 15
    • 0028955808 scopus 로고
    • TP53 mutations emerge at early phase of myelodysplastic syndrome and are associated with complex chromosomal abnormalities
    • Kaneko, H., Misawa, S., Horiike, S., Nakai, H and Kashima, K., (1995) TP53 mutations emerge at early phase of myelodysplastic syndrome and are associated with complex chromosomal abnormalities. Blood, 85, 2189-2193.
    • (1995) Blood , vol.85 , pp. 2189-2193
    • Kaneko, H.1    Misawa, S.2    Horiike, S.3    Nakai, H.4    Kashima, K.5
  • 21
    • 0026486659 scopus 로고
    • Frequent p53 gene mutations in blast crisis of chronic myelogenous leukemia, especially in myeloid crisis harboring loss of a chromosome 17p
    • Nakai, H., Misawa, S., Toguchida, J , Yandell, D. W. and Ishizaki, K. (1992) Frequent p53 gene mutations in blast crisis of chronic myelogenous leukemia, especially in myeloid crisis harboring loss of a chromosome 17p. Cancer Res., 52, 6588-6593.
    • (1992) Cancer Res. , vol.52 , pp. 6588-6593
    • Nakai, H.1    Misawa, S.2    Toguchida, J.3    Yandell, D.W.4    Ishizaki, K.5
  • 22
    • 0029118064 scopus 로고
    • Chromosome 17 abnormalities and inactivation of the p53 gene in chronic myeloid leukemia and their prognostic significance
    • Nakai, H. and Misawa, S (1995) Chromosome 17 abnormalities and inactivation of the p53 gene in chronic myeloid leukemia and their prognostic significance. Leukemia and Lymphoma, 19, 213-221.
    • (1995) Leukemia and Lymphoma , vol.19 , pp. 213-221
    • Nakai, H.1    Misawa, S.2
  • 24
    • 0027505575 scopus 로고
    • P53 gene mutations in multiple myeloma are associated with advanced forms of malignancy
    • Neri, A., Baldini, L., Trecca, D., Cro, L., Polli, E. and Maiolo, A. T. (1993) P53 gene mutations in multiple myeloma are associated with advanced forms of malignancy. Blood, 81, 128-135.
    • (1993) Blood , vol.81 , pp. 128-135
    • Neri, A.1    Baldini, L.2    Trecca, D.3    Cro, L.4    Polli, E.5    Maiolo, A.T.6
  • 26
    • 0023684505 scopus 로고
    • Chromosome abnormalities and karyotypic evolution in 83 patients with myelodysplaslic syndrome and predictive value for prognosis
    • Horiike, S., Tamwaki, M., Misawa, S and Abe, T. (1988) Chromosome abnormalities and karyotypic evolution in 83 patients with myelodysplaslic syndrome and predictive value for prognosis. Cancer. 62, 1129-1138.
    • (1988) Cancer , vol.62 , pp. 1129-1138
    • Horiike, S.1    Tamwaki, M.2    Misawa, S.3    Abe, T.4
  • 27
    • 0028928283 scopus 로고
    • Myelodysplastic syndromes and acute myeloid leukemia with 17p deletion, an entity characterized by specific dysgranulopoiesis and a high incidence of p53 mutations
    • Lai, J. L., Preudhomme. C., Zandecki, M., Flactif, M., Vanrumbeke, M., Lepelley, P., Wattel, E. and Fenaux, P. (1995) Myelodysplastic syndromes and acute myeloid leukemia with 17p deletion, an entity characterized by specific dysgranulopoiesis and a high incidence of p53 mutations. Leukemia, 9, 370-381.
    • (1995) Leukemia , vol.9 , pp. 370-381
    • Lai, J.L.1    Preudhomme, C.2    Zandecki, M.3    Flactif, M.4    Vanrumbeke, M.5    Lepelley, P.6    Wattel, E.7    Fenaux, P.8
  • 28
    • 0028227957 scopus 로고
    • Is inactivation of the p53 gene a common event in leukemias and myelodysplastic syndrome with rnonosomy 17p?
    • Nakai, H., Kaneko, H., Nakao, M., Horiike, S. and Misawa, S. (1994) Is inactivation of the p53 gene a common event in leukemias and myelodysplastic syndrome with rnonosomy 17p? Leukemia, 8, 1247-1248.
    • (1994) Leukemia , vol.8 , pp. 1247-1248
    • Nakai, H.1    Kaneko, H.2    Nakao, M.3    Horiike, S.4    Misawa, S.5
  • 29
    • 0027109075 scopus 로고
    • p53, guardian of the genome
    • Lane, D. P. (1992) p53, guardian of the genome. Nature, 358, 15-16.
    • (1992) Nature , vol.358 , pp. 15-16
    • Lane, D.P.1
  • 30
    • 0028132906 scopus 로고
    • N-ras mutation and karyotypic evolution are closely associated with leukemic transformation in myelodysplastic syndrome
    • Horiike, S., Misawa, S., Nakai, H., Kaneko, H., Yokota, S., Tamwaki, M., Yamane, Y , Inazawa, J., Abe, T. and Kashima, K. (1994) N-ras mutation and karyotypic evolution are closely associated with leukemic transformation in myelodysplastic syndrome. Leukemia, 8, 1331-1336.
    • (1994) Leukemia , vol.8 , pp. 1331-1336
    • Horiike, S.1    Misawa, S.2    Nakai, H.3    Kaneko, H.4    Yokota, S.5    Tamwaki, M.6    Yamane, Y.7    Inazawa, J.8    Abe, T.9    Kashima, K.10
  • 31
    • 0021673319 scopus 로고
    • Cooperation between gene encoding p53 tumor antigen and ras in cellular transformation
    • Parada, L. F , Land, H., Weinberg, R A., Wolf, D. and Rotter, V. (1984) Cooperation between gene encoding p53 tumor antigen and ras in cellular transformation. Nature, 312, 649-651.
    • (1984) Nature , vol.312 , pp. 649-651
    • Parada, L.F.1    Land, H.2    Weinberg, R.A.3    Wolf, D.4    Rotter, V.5
  • 32
    • 0028268635 scopus 로고
    • K-ras and p53 gene mutations in pancreatic cancer: Ductal and nonductal tumors progress through different genetic lesions
    • Pailegata, N. S., Sessa, F., Renaut, B., Bonato, M., Leone, B. E., Salcia, E and Ranzani, G. N. (1994) K-ras and p53 gene mutations in pancreatic cancer: ductal and nonductal tumors progress through different genetic lesions. Cancer Res., 54, 1556-1560.
    • (1994) Cancer Res. , vol.54 , pp. 1556-1560
    • Pailegata, N.S.1    Sessa, F.2    Renaut, B.3    Bonato, M.4    Leone, B.E.5    Salcia, E.6    Ranzani, G.N.7
  • 33
    • 1842497979 scopus 로고
    • Mutation of p53 and K-ras in intraductal papillary tumor are related to grade of epithelial dysplasia
    • Sessa. F., Pellegata, N S., Bonato, M., Capella, C., Solcia, E., Kloppel, G. and Ranzani, G. N. (1993) Mutation of p53 and K-ras in intraductal papillary tumor are related to grade of epithelial dysplasia. Digestion, 54, 308-309.
    • (1993) Digestion , vol.54 , pp. 308-309
    • Sessa, F.1    Pellegata, N.S.2    Bonato, M.3    Capella, C.4    Solcia, E.5    Kloppel, G.6    Ranzani, G.N.7
  • 36
    • 0001606206 scopus 로고
    • Major deletions in the gene coding the p53 tumor antigen cause lack of p53 expression in HL60 cells
    • Wolf, D. and Rotter, V. (1985) Major deletions in the gene coding the p53 tumor antigen cause lack of p53 expression in HL60 cells. Proc Natl Acad. Sci. USA, 82, 790-794.
    • (1985) Proc Natl Acad. Sci. USA , vol.82 , pp. 790-794
    • Wolf, D.1    Rotter, V.2
  • 37
    • 0021760789 scopus 로고
    • Three different mutations in codon 61 of the human N-ras gene detected by synthetic oligonucleotide hybridization
    • Bos, J., Verlaan-de Vries, M., Jansen, A., Veeneman, G., van Boon, J and Vander Eb A. (1984) Three different mutations in codon 61 of the human N-ras gene detected by synthetic oligonucleotide hybridization. Nucleic Acids Res., 12, 9155-9162.
    • (1984) Nucleic Acids Res. , vol.12 , pp. 9155-9162
    • Bos, J.1    Verlaan-de Vries, M.2    Jansen, A.3    Veeneman, G.4    Van Boon, J.5    Vander Eb, A.6
  • 38
    • 0027275593 scopus 로고
    • Mutations in the p53 and ras family genes are associated with tumor progression of BCR/ABL negative chronic myeloproliferative disorders
    • Gaidano, G., Guerrasio, A., Serra, A., Carozzi, F., Cambrin, G R., Petroni, D., Saglio, G (1993) Mutations in the p53 and ras family genes are associated with tumor progression of BCR/ABL negative chronic myeloproliferative disorders. Leukemia, 7, 946-953.
    • (1993) Leukemia , vol.7 , pp. 946-953
    • Gaidano, G.1    Guerrasio, A.2    Serra, A.3    Carozzi, F.4    Cambrin, G.R.5    Petroni, D.6    Saglio, G.7
  • 39
    • 0027162048 scopus 로고
    • Occurrence of point mutations in p53 gene is not increased in patients with acute myeloid leukaemia carring an activating N-ras mutation
    • Buhler-Leclerc, M., Gratwohl, A. and Senn, H. P. (1993) Occurrence of point mutations in p53 gene is not increased in patients with acute myeloid leukaemia carring an activating N-ras mutation. Brit. J. Haematol., 84, 443-450.
    • (1993) Brit. J. Haematol. , vol.84 , pp. 443-450
    • Buhler-Leclerc, M.1    Gratwohl, A.2    Senn, H.P.3
  • 40
    • 0026388053 scopus 로고
    • Genetic analysis of human esophageal tumors from two high incidence geographic areas: Frequent p53 base substitutions and absence of ras mutations
    • Hollstein, M. C., Pert, L., Mandard, A. M., Welsh, J. A., Montesano, R., Metcalf, R. A., Bak, M. and Harris, C. C. (1991) Genetic analysis of human esophageal tumors from two high incidence geographic areas: frequent p53 base substitutions and absence of ras mutations. Cancer Res., 51, 4102-4103.
    • (1991) Cancer Res. , vol.51 , pp. 4102-4103
    • Hollstein, M.C.1    Pert, L.2    Mandard, A.M.3    Welsh, J.A.4    Montesano, R.5    Metcalf, R.A.6    Bak, M.7    Harris, C.C.8
  • 41
    • 0026500545 scopus 로고
    • Mutational activation of the N-ras oncogene assessed in primary clonogenic culture of acute myeloid leukemia (AML): Implications for the role of N-ras mutation in AML pathogenesis
    • Bashey, A., Gill, R., Levi, S., Farr, C. J., Clutterbuck, R., Miller, J. L., Pragnell, I. B. and Marshall, C. J. (1992) Mutational activation of the N-ras oncogene assessed in primary clonogenic culture of acute myeloid leukemia (AML): implications for the role of N-ras mutation in AML pathogenesis. Blood, 79, 981-989.
    • (1992) Blood , vol.79 , pp. 981-989
    • Bashey, A.1    Gill, R.2    Levi, S.3    Farr, C.J.4    Clutterbuck, R.5    Miller, J.L.6    Pragnell, I.B.7    Marshall, C.J.8
  • 42
    • 0026537641 scopus 로고
    • Longitudinal analysis of point mutations of the N-ras proto-oncogene in patients with myelodysplasia using archived blood smears
    • Van Kamp, H., de Pijper, C., de Vries, M. V., Bos, J. L., Leeksma, C H. W., Krekhofs, H., Willemze, R., Fibbe, W. E. and Landegent, J. E. (1992) Longitudinal analysis of point mutations of the N-ras proto-oncogene in patients with myelodysplasia using archived blood smears. Blood, 79, 1266-1270.
    • (1992) Blood , vol.79 , pp. 1266-1270
    • Van Kamp, H.1    De Pijper, C.2    De Vries, M.V.3    Bos, J.L.4    Leeksma, C.H.W.5    Krekhofs, H.6    Willemze, R.7    Fibbe, W.E.8    Landegent, J.E.9
  • 43
    • 0025732215 scopus 로고
    • p53 gene mutational hotspot in human hepatocellular carcinomas from Qidong, China
    • Hsu, I. C., Metcalf, R. A., Sun, T., Welsh, J., Wan, N. J. and Harris. C. C. (1991) p53 gene mutational hotspot in human hepatocellular carcinomas from Qidong, China. Nature, 350, 427-428.
    • (1991) Nature , vol.350 , pp. 427-428
    • Hsu, I.C.1    Metcalf, R.A.2    Sun, T.3    Welsh, J.4    Wan, N.J.5    Harris, C.C.6
  • 44
    • 0025804270 scopus 로고
    • Mutation of the p53 gene in human acute myelogenous leukemia
    • Slingerland, J. M., Minden, M. D. and Benchimol, S. (1991) Mutation of the p53 gene in human acute myelogenous leukemia. Blood, 77, 1500-1507.
    • (1991) Blood , vol.77 , pp. 1500-1507
    • Slingerland, J.M.1    Minden, M.D.2    Benchimol, S.3
  • 45
    • 0027051310 scopus 로고
    • Structural and functional analysis of oncogenes and tumor suppressor genes in adult T-cell leukemia/lymphoma shows frequent p53 mutations
    • Cesarman, E., Chadburn, A., Inghirami, G., Gaidano, G. and Knowles, D. M. (1992) Structural and functional analysis of oncogenes and tumor suppressor genes in adult T-cell leukemia/lymphoma shows frequent p53 mutations. Blood, 80, 3205-3216.
    • (1992) Blood , vol.80 , pp. 3205-3216
    • Cesarman, E.1    Chadburn, A.2    Inghirami, G.3    Gaidano, G.4    Knowles, D.M.5
  • 47
    • 0026768030 scopus 로고
    • The pattern of p53 mutations in Burkitt's lymphoma differs from that of solid tumors
    • Bhatia, K. G., Gutierrez, M. L. Huppi, K., Siwarski, D. and Magrath, I. T. (1992) The pattern of p53 mutations in Burkitt's lymphoma differs from that of solid tumors. Cancer Res., 52, 4273-4276.
    • (1992) Cancer Res. , vol.52 , pp. 4273-4276
    • Bhatia, K.G.1    Gutierrez, M.L.2    Huppi, K.3    Siwarski, D.4    Magrath, I.T.5
  • 48
    • 0027207728 scopus 로고
    • Genetic alterations in the p53 gene in the blast crisis of chronic myelogenous leukemia: Analysis by polymerase chain reaction based techniques
    • Neubauer, A., He, M., Schmidt, C. A., Huhn, D. and Liu, E T. (1993) Genetic alterations in the p53 gene in the blast crisis of chronic myelogenous leukemia: analysis by polymerase chain reaction based techniques. Leukemia, 7, 593-600.
    • (1993) Leukemia , vol.7 , pp. 593-600
    • Neubauer, A.1    He, M.2    Schmidt, C.A.3    Huhn, D.4    Liu, E.T.5
  • 49
    • 0027954386 scopus 로고
    • Genetic analysis of p53 and RB1 tumor-suppressor genes in biast crisis of chronic myeloid leukemia
    • Gaidano, G., Serra, A., Guerrasio, A., Rege-Cambrin, G., Mazza, U. and Saglio, G. (1994) Genetic analysis of p53 and RB1 tumor-suppressor genes in biast crisis of chronic myeloid leukemia. Ann. Hematol., 68, 3-7.
    • (1994) Ann. Hematol. , vol.68 , pp. 3-7
    • Gaidano, G.1    Serra, A.2    Guerrasio, A.3    Rege-Cambrin, G.4    Mazza, U.5    Saglio, G.6
  • 50
    • 0022617302 scopus 로고
    • Clinical and cytogenetic correlations in 63 patients with therapy-related myelodysplastic syndromes and acute nonlymphocytic leukemia: Further evidence for characteristic abnormalities of chromosomes No. 5 and 7
    • Le Beau, M. M., Albain, K S., Larson, R. A., Vardiman, J. W., Davis, E. M., Blough, R. B , Golomb, H. M. and Rowley, J. D. (1986) Clinical and cytogenetic correlations in 63 patients with therapy-related myelodysplastic syndromes and acute nonlymphocytic leukemia: further evidence for characteristic abnormalities of chromosomes No. 5 and 7. J. Clin. Oncol., 4, 325-345.
    • (1986) J. Clin. Oncol. , vol.4 , pp. 325-345
    • Le Beau, M.M.1    Albain, K.S.2    Larson, R.A.3    Vardiman, J.W.4    Davis, E.M.5    Blough, R.B.6    Golomb, H.M.7    Rowley, J.D.8
  • 51
    • 0027722155 scopus 로고
    • Therapy-related myelodysplasia and acute myeloid leukemia, cytogenetic characteristics of 115 concecutive cases and risk in seven cohorts of patients treated intensively for malignant diseases in the Copenhagen Series
    • Pedersen-Bjergaard, J , Philip, P., Larsen, S. O., Andersson, M., Daugaard, G , Ersboell, J., Hansen, S. W., Hou-Jensen, K., Nielsen, D., Sigsgaard, T C., Specht, L. and Oesterlind, K. (1993) Therapy-related myelodysplasia and acute myeloid leukemia, cytogenetic characteristics of 115 concecutive cases and risk in seven cohorts of patients treated intensively for malignant diseases in the Copenhagen Series. Leukemia, 7, 1975-1986.
    • (1993) Leukemia , vol.7 , pp. 1975-1986
    • Pedersen-Bjergaard, J.1    Philip, P.2    Larsen, S.O.3    Andersson, M.4    Daugaard, G.5    Ersboell, J.6    Hansen, S.W.7    Hou-Jensen, K.8    Nielsen, D.9    Sigsgaard, T.C.10    Specht, L.11    Oesterlind, K.12


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.