Spontaneous and aphidicolin-sensitive fragile site 3cen co-localizes with the (TTAGGG)n telomeric sequence in Chinese hamster cells

Cytogenetics and Cell Genetics

Volumn 75, Issue 2-3, 1996, Pages 159-163

  Musio, A ^a   Rainaldi, G ^b   Sbrana, I ^a  

^a UNIVERSITY OF PISA   (Italy)

^b CNR   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

APHIDICOLIN; DNA;

ANIMAL CELL; ARTICLE; CARCINOGENICITY; CENTROMERE; CHINESE HAMSTER; CHROMOSOME 3; CHROMOSOME ABERRATION; CHROMOSOME FRAGILE SITE; DNA SEQUENCE; FIBROBLAST; FLUORESCENCE IN SITU HYBRIDIZATION; GENE LOCATION; NONHUMAN; PRIORITY JOURNAL; TELOMERE;

ANIMALS; APHIDICOLIN; BASE SEQUENCE; CELL LINE; CELL LINE, TRANSFORMED; CHROMOSOME ABERRATIONS; CHROMOSOME BREAKAGE; CHROMOSOME FRAGILE SITES; CHROMOSOME FRAGILITY; CRICETINAE; CRICETULUS; IN SITU HYBRIDIZATION, FLUORESCENCE; TELOMERE; TUMOR CELLS, CULTURED;

ANIMALIA; CRICETINAE; CRICETULUS GRISEUS;

EID: 0030462550     PISSN: 03010171     EISSN: 1424859X     Source Type: Journal    
DOI: 10.1159/000134469     Document Type: Article

References (26)

1. Ahuja YR: Fragile sites analysis: its significance in environmental mutagenesis, in Mutation and Environment. Part B, pp. 371-384 (Wiley-Liss. New York 1990).
2. Alvarez L, Evans JW, Wilks R, Lucas JN, Brown JM, Giaccia AJ: Chromosomal radiosensitivity at in-trachromosomal telomeric sites. Genes Chrom Cancer 8:8-14 (1993).
3. Borgaonkar DS: Chromosomal Variation in Man: A Catalog of Chromosomal Variants and Anomalies. 6th Ed (Alan R. Liss, New York 1991).
4. Farr C, Fantes J, Goodfellow P, Cooke H: Functional réintroduction of human telomeres into mammalian cells. Proc natl Acad Sci. USA 88:7006-7010 (1991).
5. Glover TW, Stein CK: Induction of sister chromatid exchanges at common fragile sites. Am J hum Genet 41:882-890 (1987).
6. Glover TW, Stein CK: Chromosome breakage and recombination at fragile sites. Am J hum Genet 43:265-273(1988).
7. Hastie NO, Allshire RC: Human telomeres: fusion and interstitial sites. Trends Genet 5:326-331 (1989).
8. Ijdo JW, Baldini A, Wells RA, Ward DC, Reeders ST: FRA2B is distinct from inverted telomere repeat arrays at 2q 13. Genomics 12:833-835 (1992).
9. Kuo TM, Vyas CR, Jiang LX, Hittelman WN: Chromosome breakage at a major fragile site associated with p-glycoprotein gene amplification in multidrug-resistant CHO cells. Mol Cell Biol 14:5202-5211 (1994).
10. Lin MS, Takabayashi T, Wilson MG, Marchese CA: An in vitro and in vivo study of BrdU-sensitive fragile site in the Chinese hamster. Cytogenet Cell Genet 38:211-215(1984).
11. Mariani T: Fragile sites and statistics. Hum Genet 81:319-322(1989).
12. Musio A, Sbrana I: Common and rare fragile sites on human chromosomes: the cytogenetic expression of active and inactive genes? Cancer Genet Cyto-genct 88:184-185(1996).
13. Ozisik YY, Meloni AM, Stone JF, Sandberg AA, Surti U: Spontaneous expression of the chromosomal fragile site at 10q23 in leiomyoma. Cancer Genet Cytogenet 74:73-75 (1994).
14. Pandita TK, DeRubcis D: Spontaneous amplification of interstitial telomeric bands in Chinese hamster ovary cells. Cytogenet Cell Genet 68:95-101 (1995).
15. Pieretti M, Zhang F, Fu YH, Warren ST, Oostra BA, Caskey CT, Nelson DL: Absence of expression of the FMRI gene in fragile X syndrome. Cell 66:817-822(1991).
16. Ray AF, Bartholdi MF, Kraemer PM, Cram LS: Spontaneous in vitro neoplastic evolution: recurrent chromosome changes of newly immortalized Chinese hamster cell. Cancer Genet Cytogenet 21:35-51 (1986).
17. Ray M, Mohandas T: Proposed banding nomenclature for the Chinese hamster chromosomes(Cricetulus griseus).Cytogenet Cell Genet 16:83-91 (1976).
18. Sbrana I, Musio A: Enhanced expression of common fragile sites and occupational exposure to pesticides. Cancer Genet Cytogenet 82:123-127 (1995).
19. Simi S, Colella CM, Mariani T, Piras A, Rainaldi G: Qualilative analysis of chromosomal evolution in a Colcemid-treated Chinese hamster population. Teratogen Carcinogen Mutagen 1:45-54 (1988).
20. Simi S, Musio A, Vattcroni L, Piras A, Rainaldi G: Specific chromosomal aberrations correlated to transformation in Chinese hamster cells, Cancer Genet Cytogenet 62:81-87 (1992).
21. Simi S, Vattcroni L, Piras A, Mariani T, Rainaldi G: Folate-sensitive fragile sites in Chinese hamster cell lines. Cancer Genet Cytogenet 46:209-216 (1990).
22. Thacker J: The chromosomes of a V79 Chinese hamster line and a mutant subline lacking I IPRT activity. Cytogenet Cell Genet 29:16-25 (1981).
23. Vatteroni L, Piras A, Mariani T, Caligo MA, Rainaldi G: Accumulation of anchorage independent cells showing amplified (CAD) during the in vitro propagation of CHEF18 Chinese hamster cells. Cell Prolif 26:161-170 (1993).
24. Wells RA, Germino GG, Krishna S, Buckle VJ, Reeders ST: Telomere-related sequences at interstitial sites in the human genome. Genomics 8:699-704 (1990).
25. Worton RG, Ho CC, Duff C: Chromosome stability in CHO cells. Somat Cell Genet 3:27-45 (1977).
26. Yunis JJ, Soreng AL: Constitutive fragile sites and cancer. Science 226:1199-1204 (1984).