Synthesis and bioevaluation of Δ7-5-desaturase inhibitors, an enzyme late in the biosynthesis of the fungal sterol ergosterol

Journal of Medicinal Chemistry

Volumn 39, Issue 26, 1996, Pages 5092-5099

  Goldstein, Alex S ^a,b  

^a RENSSELAER POLYTECHNIC INSTITUTE   (United States)

^b UNIVERSITY OF WASHINGTON   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ERGOSTEROL;

ACQUIRED IMMUNE DEFICIENCY SYNDROME; ANTIFUNGAL ACTIVITY; ARTICLE; AUXOTROPHIC MUTANT; CELL FUNCTION; DRUG SYNTHESIS; ENZYME INHIBITION; ENZYME SUBSTRATE; FATTY ACID DESATURATION; FUNGUS GROWTH; MYCOSIS; NONHUMAN; STEROL SYNTHESIS;

ENZYME INHIBITORS; ERGOSTEROL; FUNGI; MAGNETIC RESONANCE SPECTROSCOPY; MASS SPECTROMETRY; OXIDOREDUCTASES; OXIDOREDUCTASES ACTING ON CH-CH GROUP DONORS; SPECTROPHOTOMETRY, INFRARED;

EID: 0030462244     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm9605851     Document Type: Article

References (37)

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