-
1
-
-
0023034527
-
Rat-liver microsomal cytochrome P-450: Purification, characterization, multiplicity and induction
-
Åström, A., and Depierre, J. W. (1986). Rat-liver microsomal cytochrome P-450: Purification, characterization, multiplicity and induction. Biochem. Biophys. Acta 853, 1-26.
-
(1986)
Biochem. Biophys. Acta
, vol.853
, pp. 1-26
-
-
Åström, A.1
Depierre, J.W.2
-
2
-
-
0017184389
-
A rapid and sensitive method for the quantitation of microgram quantities of utilizing the principle of protein-dye binding
-
Bradford, M. M. (1976). A rapid and sensitive method for the quantitation of microgram quantities of utilizing the principle of protein-dye binding. Anal. Biochem. 72, 248-254.
-
(1976)
Anal. Biochem.
, vol.72
, pp. 248-254
-
-
Bradford, M.M.1
-
3
-
-
0024448789
-
Induction of cytochrome P450IIE1 and P450IIB1 by secondary ketones and the role of P450IIE1 in chloroform metabolism
-
Brady, J. F., Dechun, L., Ishizaki, H., Lee, M., Ning, S. M., Xiao, F., and Yang, C. S. (1989). Induction of cytochrome P450IIE1 and P450IIB1 by secondary ketones and the role of P450IIE1 in chloroform metabolism. Toxicol. Appl. Pharmacol. 100, 342-349.
-
(1989)
Toxicol. Appl. Pharmacol.
, vol.100
, pp. 342-349
-
-
Brady, J.F.1
Dechun, L.2
Ishizaki, H.3
Lee, M.4
Ning, S.M.5
Xiao, F.6
Yang, C.S.7
-
4
-
-
0023837914
-
Diethyl ether as a substrate for acetone/ethanol-inducible cytochrome P-450 and as an inducer for cytochrome(s) P-450
-
Brady, J. F., Lee, M. J., Li, M., Ishizaki, H., and Yang, C. S. (1988). Diethyl ether as a substrate for acetone/ethanol-inducible cytochrome P-450 and as an inducer for cytochrome(s) P-450. Mol. Pharmacol. 33, 148-154.
-
(1988)
Mol. Pharmacol.
, vol.33
, pp. 148-154
-
-
Brady, J.F.1
Lee, M.J.2
Li, M.3
Ishizaki, H.4
Yang, C.S.5
-
5
-
-
0021044207
-
Comparison of the effects of methyl n-butyl ketone and phenobarbital on rat liver cytochrome P-450 and metabolism of chloroform to phosgene
-
Branchflower, R. V., Schulick, R. D., George, J. W., and Pohl, L. R. (1983). Comparison of the effects of methyl n-butyl ketone and phenobarbital on rat liver cytochrome P-450 and metabolism of chloroform to phosgene. Toxicol. Appl. Pharmacol. 71, 414-421.
-
(1983)
Toxicol. Appl. Pharmacol.
, vol.71
, pp. 414-421
-
-
Branchflower, R.V.1
Schulick, R.D.2
George, J.W.3
Pohl, L.R.4
-
6
-
-
0022357068
-
Ethoxy-, pentoxy- and benzyloxyphenoxazones and homologues: A series of substrates to distinguish between different induced cytochrome P-450
-
Burke, M. D., Thompson, S., Elcombe, C. R., Halpert, J., Haaparanta, T., and Mayer, R. T. (1985). Ethoxy-, pentoxy- and benzyloxyphenoxazones and homologues: A series of substrates to distinguish between different induced cytochrome P-450. Biochem. Pharmacol. 34, 3337-3345.
-
(1985)
Biochem. Pharmacol.
, vol.34
, pp. 3337-3345
-
-
Burke, M.D.1
Thompson, S.2
Elcombe, C.R.3
Halpert, J.4
Haaparanta, T.5
Mayer, R.T.6
-
7
-
-
0026655580
-
Dichloroacetic acid and trichloroacetic acid increase chloroform toxicity
-
Davis, M. E. (1992). Dichloroacetic acid and trichloroacetic acid increase chloroform toxicity. J. Toxicol. Environ. Health 37, 139-148.
-
(1992)
J. Toxicol. Environ. Health
, vol.37
, pp. 139-148
-
-
Davis, M.E.1
-
8
-
-
0023914486
-
Mechanism of induction of cytochrome P-450ac (P-450j) in chemically induced and spontaneously diabetic rats
-
Dong, Z. G., Hong, J. Y., Ma, Q. A., Li, D. C., Bullock, J., Gonzalez, F. J., Park, S. S., Gelboin, H. V., and Yang, C. S. (1988). Mechanism of induction of cytochrome P-450ac (P-450j) in chemically induced and spontaneously diabetic rats. Arch. Biochem. Biophys. 263, 29-35.
-
(1988)
Arch. Biochem. Biophys.
, vol.263
, pp. 29-35
-
-
Dong, Z.G.1
Hong, J.Y.2
Ma, Q.A.3
Li, D.C.4
Bullock, J.5
Gonzalez, F.J.6
Park, S.S.7
Gelboin, H.V.8
Yang, C.S.9
-
9
-
-
0016758752
-
The role of microsomal hydroxylases in the modification of chloroform hepatotoxicity in rats
-
Gopinath, C., and Ford, E. J. H. (1975). The role of microsomal hydroxylases in the modification of chloroform hepatotoxicity in rats. Brit. J. Exp. Pathol. 56, 412-422.
-
(1975)
Brit. J. Exp. Pathol.
, vol.56
, pp. 412-422
-
-
Gopinath, C.1
Ford, E.J.H.2
-
10
-
-
0026035519
-
Role of human cytochrome P-450 IIE1 in the oxidation of many low molecular weight cancer suspects
-
Guengerich, F. P., Kim, D-H., and Iwasaki, M. (1990). Role of human cytochrome P-450 IIE1 in the oxidation of many low molecular weight cancer suspects. Chem. Res. Toxicol. 4, 168-179.
-
(1990)
Chem. Res. Toxicol.
, vol.4
, pp. 168-179
-
-
Guengerich, F.P.1
Kim, D.-H.2
Iwasaki, M.3
-
11
-
-
0019307193
-
Acute alteration of chloroform-induced hepato- and nephrotoxicity by n-hexane, methyl n-butyl ketone, and 2,5-hexanedione
-
Hewitt, W. R., Miyajima, H. M., Côté, G., and Plaa, G. L. (1980). Acute alteration of chloroform-induced hepato- and nephrotoxicity by n-hexane, methyl n-butyl ketone, and 2,5-hexanedione. Toxicol. Appl. Pharmacol. 53, 230-248.
-
(1980)
Toxicol. Appl. Pharmacol.
, vol.53
, pp. 230-248
-
-
Hewitt, W.R.1
Miyajima, H.M.2
Côté, G.3
Plaa, G.L.4
-
12
-
-
0023882996
-
The role of biotransformation-detoxication in acetone-, 2-butanone-, and 2-hexanone-potentiated chloroform-induced hepatotoxicity
-
Hewitt, L. A., Valiquette, C., and Plaa, G. L. (1987). The role of biotransformation-detoxication in acetone-, 2-butanone-, and 2-hexanone-potentiated chloroform-induced hepatotoxicity. Can. J. Physiol. Pharmacol. 65, 2313-2318.
-
(1987)
Can. J. Physiol. Pharmacol.
, vol.65
, pp. 2313-2318
-
-
Hewitt, L.A.1
Valiquette, C.2
Plaa, G.L.3
-
13
-
-
0023143955
-
The induction of a specific form of cytochrome P-450(P450j) by fasting
-
Hong, J., Pan, J., Gonzalez, F. J., Gelboin, H. V., and Yang, C. S. (1987). The induction of a specific form of cytochrome P-450(P450j) by fasting. Biochem. Biophys. Res. Commun. 142, 1077-1083.
-
(1987)
Biochem. Biophys. Res. Commun.
, vol.142
, pp. 1077-1083
-
-
Hong, J.1
Pan, J.2
Gonzalez, F.J.3
Gelboin, H.V.4
Yang, C.S.5
-
14
-
-
0015815394
-
Chloroform toxicity in mice: Correlation of renal and hepatic necrosis and covalent binding of metabolites to tissue macromolecules
-
Ilett, K. F., Reid, W. D., Sipes, I. G., and Krishna, G. (1973). Chloroform toxicity in mice: Correlation of renal and hepatic necrosis and covalent binding of metabolites to tissue macromolecules. Exp. Mol. Pathol. 19, 215-229.
-
(1973)
Exp. Mol. Pathol.
, vol.19
, pp. 215-229
-
-
Ilett, K.F.1
Reid, W.D.2
Sipes, I.G.3
Krishna, G.4
-
15
-
-
0013958297
-
Evidence for biochemically different types of vesicles in the hepatic microsomal fraction
-
Imai, Y., Ito, A., and Sato, R. (1966). Evidence for biochemically different types of vesicles in the hepatic microsomal fraction. J. Biochem (Tokyo). 60, 417-441.
-
(1966)
J. Biochem (Tokyo)
, vol.60
, pp. 417-441
-
-
Imai, Y.1
Ito, A.2
Sato, R.3
-
16
-
-
0021815153
-
Carbon tetrachloride-induced lipid peroxidation dependent on an ethanol-inducible form of rabbit liver microsomal cytochrome P-450
-
Johansson, I., and Ingelman Sundberg, M. (1985). Carbon tetrachloride-induced lipid peroxidation dependent on an ethanol-inducible form of rabbit liver microsomal cytochrome P-450. FEBS Lett. 183, 265-269.
-
(1985)
FEBS Lett.
, vol.183
, pp. 265-269
-
-
Johansson, I.1
Ingelman Sundberg, M.2
-
17
-
-
0023685311
-
Benzene metabolism by ethanol-, acetone-, and benzene-inducible cytochrome P-450 (IIE1) in rat and rabbit liver microsomes
-
Johansson, I., and Ingelman Sundberg, M. (1988). Benzene metabolism by ethanol-, acetone-, and benzene-inducible cytochrome P-450 (IIE1) in rat and rabbit liver microsomes. Cancer Res. 48, 5387-5390.
-
(1988)
Cancer Res.
, vol.48
, pp. 5387-5390
-
-
Johansson, I.1
Ingelman Sundberg, M.2
-
18
-
-
0003107009
-
D-(-)-3-Hydroxybutyrate and acetoacetate
-
H. U. Bergmeyer, Ed. VCH, Weinheim
-
Kientsch-Engel, R. I., and Siess, E. A. (1985). D-(-)-3-Hydroxybutyrate and acetoacetate. In Methods of Enzymatic Analysis, Vol. VIII, Metabolites 3: Lipids, Amino Acids and Related Compounds (H. U. Bergmeyer, Ed.), pp. 60-69. VCH, Weinheim.
-
(1985)
Methods of Enzymatic Analysis, Vol. VIII, Metabolites 3: Lipids, Amino Acids and Related Compounds
, vol.8
, pp. 60-69
-
-
Kientsch-Engel, R.I.1
Siess, E.A.2
-
19
-
-
0024459896
-
Effects of acetone and methyl n-butyl ketone on hepatic mixed-function oxidase
-
Kobusch, A. B., Plaa, G. L., and du Souich, P. (1989). Effects of acetone and methyl n-butyl ketone on hepatic mixed-function oxidase. Biochem. Pharmacol. 38, 3461-3467.
-
(1989)
Biochem. Pharmacol.
, vol.38
, pp. 3461-3467
-
-
Kobusch, A.B.1
Plaa, G.L.2
Du Souich, P.3
-
20
-
-
0022494453
-
Hydroxylation of p-nitrophenol by rabbit ethanol-inducible cytochrome P-450 isozyme 3a
-
Koop, D. R. (1986). Hydroxylation of p-nitrophenol by rabbit ethanol-inducible cytochrome P-450 isozyme 3a. Mol. Pharmacol. 29, 399-404.
-
(1986)
Mol. Pharmacol.
, vol.29
, pp. 399-404
-
-
Koop, D.R.1
-
21
-
-
0022827585
-
Ethanol oxidation and toxicity: Role of alcohol P-450 oxygenase
-
Koop, D. R., and Coon, M. J. (1986). Ethanol oxidation and toxicity: Role of alcohol P-450 oxygenase. Alcoholism Clin. Exp. Res. 10, 44s-49s.
-
(1986)
Alcoholism Clin. Exp. Res.
, vol.10
-
-
Koop, D.R.1
Coon, M.J.2
-
22
-
-
0014949207
-
Cleavage of structural proteins during the assembly of the head of bacteriophage T4
-
Laemmli, U. K. (1970). Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227, 680-685.
-
(1970)
Nature
, vol.227
, pp. 680-685
-
-
Laemmli, U.K.1
-
23
-
-
0016229747
-
The role of metabolism in chloroform hepatotoxicity
-
Lavigne, J-G., and Marchand, C. (1974). The role of metabolism in chloroform hepatotoxicity. Toxicol. Appl. Pharmacol. 29, 312-326.
-
(1974)
Toxicol. Appl. Pharmacol.
, vol.29
, pp. 312-326
-
-
Lavigne, J.-G.1
Marchand, C.2
-
24
-
-
0022350885
-
Dealkylation of pentoxyresorufin: A rapid and sensitive assay for measuring induction of cytochrome(s) P-450 by phenobarbital and other xenobiotics in the rats
-
Lubet, R. A., Mayer, R. T., Cameron, J. W., Nims, R. W., Burke, M. D., Wolff, T., and Guengerich, F. P. (1985). Dealkylation of pentoxyresorufin: a rapid and sensitive assay for measuring induction of cytochrome(s) P-450 by phenobarbital and other xenobiotics in the rats. Arch. Biochem. Biophys. 238, 43-48.
-
(1985)
Arch. Biochem. Biophys.
, vol.238
, pp. 43-48
-
-
Lubet, R.A.1
Mayer, R.T.2
Cameron, J.W.3
Nims, R.W.4
Burke, M.D.5
Wolff, T.6
Guengerich, F.P.7
-
25
-
-
0020465448
-
Catalytic activity of cytochrome P-450 isozyme 3a isolated from liver microsomes of ethanol-treated rabbits
-
Morgan, E. T., Koop, D. R., and Coon, M. J. (1982). Catalytic activity of cytochrome P-450 isozyme 3a isolated from liver microsomes of ethanol-treated rabbits. J. Biol. Chem. 257, 13951-13957.
-
(1982)
J. Biol. Chem.
, vol.257
, pp. 13951-13957
-
-
Morgan, E.T.1
Koop, D.R.2
Coon, M.J.3
-
26
-
-
0029117051
-
Different contributions of cytochrome P450 2E1 and P450 2B1/2 to chloroform hepatotoxicity in rat
-
Nakajima, T., Elovaara, E., Okino, T., Gelboin, H. V., Klockards, M., Riihimaki, V., Aoyama, T., and Vainio, H. (1995). Different contributions of cytochrome P450 2E1 and P450 2B1/2 to chloroform hepatotoxicity in rat. Toxicol. Appl. Pharmacol. 133, 215-222.
-
(1995)
Toxicol. Appl. Pharmacol.
, vol.133
, pp. 215-222
-
-
Nakajima, T.1
Elovaara, E.2
Okino, T.3
Gelboin, H.V.4
Klockards, M.5
Riihimaki, V.6
Aoyama, T.7
Vainio, H.8
-
27
-
-
0025769280
-
Immunochemical detection of cytochrome P450 isozymes induced in rat liver by n-hexane, 2-hexanone and acetonyl acetone
-
Nakajima, T., Elovaara, E., Park, S. S., Gelboin, H. V., and Vainio, H. (1991). Immunochemical detection of cytochrome P450 isozymes induced in rat liver by n-hexane, 2-hexanone and acetonyl acetone. Arch. Toxicol. 65, 542-547.
-
(1991)
Arch. Toxicol.
, vol.65
, pp. 542-547
-
-
Nakajima, T.1
Elovaara, E.2
Park, S.S.3
Gelboin, H.V.4
Vainio, H.5
-
28
-
-
0025262126
-
Three forms of trichloroethylene-metabolizing enzymes in rat liver induced by ethanol, phenobarbital, and 3-methylchloanthrene
-
Nakajima, T., Wang, R. S., Murayama, N., and Sato, A. (1990). Three forms of trichloroethylene-metabolizing enzymes in rat liver induced by ethanol, phenobarbital, and 3-methylchloanthrene. Toxicol. Appl. Pharmacol. 102, 546-552.
-
(1990)
Toxicol. Appl. Pharmacol.
, vol.102
, pp. 546-552
-
-
Nakajima, T.1
Wang, R.S.2
Murayama, N.3
Sato, A.4
-
29
-
-
0023178314
-
Kinetic studies on benzene metabolism in rat liver-possible presence of three forms of benzene metabolizing enzymes in the liver
-
Nakajima, T., Okino, T., and Sato, A. (1987). Kinetic studies on benzene metabolism in rat liver-possible presence of three forms of benzene metabolizing enzymes in the liver. Biochem. Pharmacol. 36, 2799-2804.
-
(1987)
Biochem. Pharmacol.
, vol.36
, pp. 2799-2804
-
-
Nakajima, T.1
Okino, T.2
Sato, A.3
-
30
-
-
78651165715
-
The carbon monoxide-binding pigment of liver microsomes. I. Evidence for its hemoprotein nature
-
Omura, T. S., and Sato, R. (1964). The carbon monoxide-binding pigment of liver microsomes. I. Evidence for its hemoprotein nature. J. Biol. Chem. 239, 2370-2378.
-
(1964)
J. Biol. Chem.
, vol.239
, pp. 2370-2378
-
-
Omura, T.S.1
Sato, R.2
-
31
-
-
73849173955
-
Hepatic triphosphopyridine nucleotide-cytochrome c reductase: Isolation, characterization, and kinetic studies
-
Phillips, A. H., and Langdon, R. G. (1962). Hepatic triphosphopyridine nucleotide-cytochrome c reductase: Isolation, characterization, and kinetic studies. J. Biol. Chem. 237, 2652-2660.
-
(1962)
J. Biol. Chem.
, vol.237
, pp. 2652-2660
-
-
Phillips, A.H.1
Langdon, R.G.2
-
32
-
-
0017717889
-
Phosgene: A metabolite of chloroform
-
Pohl, L. R., Bhooshan, B., Whittaker, N. F., and Krishna, G. (1977). Phosgene: A metabolite of chloroform. Biochem. Biophys. Res. Commun. 79, 684-691.
-
(1977)
Biochem. Biophys. Res. Commun.
, vol.79
, pp. 684-691
-
-
Pohl, L.R.1
Bhooshan, B.2
Whittaker, N.F.3
Krishna, G.4
-
33
-
-
0025805616
-
Induction of cytochrome P450IIE1 in the obese overfed rat
-
Raucy, J. L., Lasker, J. M., Kraner, J. C., Salazar, D. E., Lieber, C. S., and Corcoran, G. B. (1991). Induction of cytochrome P450IIE1 in the obese overfed rat. Mol. Pharmacol. 39, 275-280.
-
(1991)
Mol. Pharmacol.
, vol.39
, pp. 275-280
-
-
Raucy, J.L.1
Lasker, J.M.2
Kraner, J.C.3
Salazar, D.E.4
Lieber, C.S.5
Corcoran, G.B.6
-
35
-
-
0020368740
-
Purification, characterization and regulation of five rat hepatic microsomal cytochrome P-450 isozymes
-
Ryan, D. E., Thomas, P. E., Reik, L. M., and Levin, W. (1982). Purification, characterization and regulation of five rat hepatic microsomal cytochrome P-450 isozymes. Xenobiotica 12, 727-744.
-
(1982)
Xenobiotica
, vol.12
, pp. 727-744
-
-
Ryan, D.E.1
Thomas, P.E.2
Reik, L.M.3
Levin, W.4
-
36
-
-
77957175211
-
Chronic toxicity of dichloroacetate: Possible relation to thiamine deficiency in rats
-
Stacpoole, P. W., Harwood, H. J. J., Cameron, D. F., Curry, S. H., Samuelson, D. A., Cornwell, P. E., and Sauberlich, H. E. (1990). Chronic toxicity of dichloroacetate: Possible relation to thiamine deficiency in rats. Fundam. Appl. Toxicol. 14, 327-337.
-
(1990)
Fundam. Appl. Toxicol.
, vol.14
, pp. 327-337
-
-
Stacpoole, P.W.1
Harwood, H.J.J.2
Cameron, D.F.3
Curry, S.H.4
Samuelson, D.A.5
Cornwell, P.E.6
Sauberlich, H.E.7
-
37
-
-
0023180336
-
Regulation of cytochrome P-450j, a high-affinity N-nitrosodimethylamine demethylase, in rat hepatic microsomes
-
Thomas, P. E., Bandiera, S., Maines, S. L., Ryan, D. E., and Levin, W. (1987). Regulation of cytochrome P-450j, a high-affinity N-nitrosodimethylamine demethylase, in rat hepatic microsomes. Biochemistry 26, 2280-2289.
-
(1987)
Biochemistry
, vol.26
, pp. 2280-2289
-
-
Thomas, P.E.1
Bandiera, S.2
Maines, S.L.3
Ryan, D.E.4
Levin, W.5
-
38
-
-
0022414627
-
Activation of chloroform and related trihalomethanes to free radical intermediates in isolated hepatocytes and in the rat in vivo as detected by the ESR-spin trapping technique
-
Tomasi, A., Albano, E., Biasi, F., Slater, T. F., Vannini, V., and Dianzani, M. U. (1985). Activation of chloroform and related trihalomethanes to free radical intermediates in isolated hepatocytes and in the rat in vivo as detected by the ESR-spin trapping technique. Chem. Biol. Interact. 55, 303-316.
-
(1985)
Chem. Biol. Interact.
, vol.55
, pp. 303-316
-
-
Tomasi, A.1
Albano, E.2
Biasi, F.3
Slater, T.F.4
Vannini, V.5
Dianzani, M.U.6
-
39
-
-
0025167020
-
Cytochrome P450IIE1: Roles in nitrosamine metabolism and mechanisms of regulation
-
Yang, C. S., Yoo, J. S. H., Ishizaki, H., and Hong, J. (1990). Cytochrome P450IIE1: Roles in nitrosamine metabolism and mechanisms of regulation. Drug Metab. Rev. 22, 147-159.
-
(1990)
Drug Metab. Rev.
, vol.22
, pp. 147-159
-
-
Yang, C.S.1
Yoo, J.S.H.2
Ishizaki, H.3
Hong, J.4
-
40
-
-
0021958785
-
Metabolism of nitrosamines by purified rabbit liver cytochrome P-450 isozymes
-
Yang, C. S., Tu, Y. Y., Koop, D. R., and Coon, M. J. (1985). Metabolism of nitrosamines by purified rabbit liver cytochrome P-450 isozymes. Cancer Res. 45, 1140-1145.
-
(1985)
Cancer Res.
, vol.45
, pp. 1140-1145
-
-
Yang, C.S.1
Tu, Y.Y.2
Koop, D.R.3
Coon, M.J.4
-
43
-
-
0025129181
-
Effects of thiamine deficiency on hepatic cytochromes P450 and drug-metabolizing enzyme activities
-
Yoo, J. S., Park, H., Ning, S. M., Lee, M., and Yang, C. S. (1990). Effects of thiamine deficiency on hepatic cytochromes P450 and drug-metabolizing enzyme activities. Biochem. Pharmacol. 39, 519-525.
-
(1990)
Biochem. Pharmacol.
, vol.39
, pp. 519-525
-
-
Yoo, J.S.1
Park, H.2
Ning, S.M.3
Lee, M.4
Yang, C.S.5
-
44
-
-
0019994207
-
Comparison of the metabolic and toxic effects of 2-chloropropionate and dichloroacetate
-
Yount, E. A., Felten, S. Y., O'Connor, B. L., Peterson, R. G., Powell, R. S., Yum, M. N., and Harris, R. A. (1982). Comparison of the metabolic and toxic effects of 2-chloropropionate and dichloroacetate. J. Pharmacol. Exp. Ther. 222, 501-508.
-
(1982)
J. Pharmacol. Exp. Ther.
, vol.222
, pp. 501-508
-
-
Yount, E.A.1
Felten, S.Y.2
O'Connor, B.L.3
Peterson, R.G.4
Powell, R.S.5
Yum, M.N.6
Harris, R.A.7
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