Contributions of donor CD4 and CD8 cells to liver injury during murine graft-versus-host disease

Transplantation

Volumn 62, Issue 11, 1996, Pages 1621-1628

  Li, Jian ^a   Helm, Karen ^b   Howell, Charles D ^a,b,c  

^a UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF COLORADO SCHOOL OF MEDICINE   (United States)

^c NONE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN E; OKT 4; OKT 8;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; FEMALE; GRAFT VERSUS HOST REACTION; HISTOPATHOLOGY; LIVER INJURY; LIVER TRANSPLANTATION; LYMPHOCYTE DEPLETION; MICROPHOTOGRAPHY; MOUSE; NONHUMAN; ORGAN DONOR; PRIORITY JOURNAL; SCORING SYSTEM;

ANIMALS; ANTIBODIES, MONOCLONAL; ANTIGENS, CD4; ANTIGENS, CD8; CD4-POSITIVE T-LYMPHOCYTES; CD8-POSITIVE T-LYMPHOCYTES; FEMALE; GRAFT VS HOST DISEASE; IMMUNOSUPPRESSIVE AGENTS; LIVER; LIVER DISEASES; MICE; MICE, INBRED BALB C; MICE, INBRED STRAINS;

EID: 0030460772     PISSN: 00411337     EISSN: None     Source Type: Journal    
DOI: 10.1097/00007890-199612150-00016     Document Type: Article

References (35)

1. Ringden O, Horowitz MM, Sondel P, et al. Methotrexate, cyclosporine, or both to prevent graft-versus-host disease after HLA-identical sibling bone marrow transplants for early leukemia? Blood 1993; 81(4): 1094.
2. Mrsic M, Labar B, Bogdanic V, et al. Combination of cyclosporin and methotrexate for prophylaxis of acute graft-versus-host disease after allogeneic bone marrow transplantation for leukemia. Bone Marrow Transplant 1990; 6(2): 137.
3. Shulman HM, Sharma P, Amos D, Fenster LF, McDonald GB. A coded histologic study of hepatic graft-versus-host disease after human bone marrow transplantation. Hepatology 1988; 8(3): 463.
4. Kemnitz J, Ringe B, Cohnert TR, Gubernatis G, Choritz H, Georgii A. Bile duct injury as a part of diagnostic criteria for liver allograft rejection. Hum Pathol 1989; 20(2): 132.
5. Ludwig J, Dickson ER, McDonald GS. Staging of chronic non-suppurative destructive cholangitis (syndrome of primary biliary cirrhosis). Virchows Arch A Pathol Anat Histol 1978; 379(2): 103.
6. Vierling JM, Fennell RH Jr. Histopathology of early and late human hepatic allograft rejection: evidence of progressive destruction of interlobular bile ducts. Hepatology 1985; 5(6): 1076.
7. Bernuau D, Feldmann G, Degott C, Gisselbrecht C. Ultrastructural lesions of bile ducts in primary biliary cirrhosis. A comparison with the lesions observed in graft versus host disease. Hum Pathol 1981; 12(9): 782.
8. Howell CD, Yoder T, Claman HN, Vierling JM. Hepatic homing of mononuclear inflammatory cells isolated during murine chronic graft-vs-host disease. J Immunol 1989; 143(2): 476.
9. Howell CD, Yoder TD, Vierling JM. Suppressor function of hepatic mononuclear inflammatory cells during murine chronic graft-vs-host disease. I. Macrophage-enriched cells mediate suppression in the liver. Cell Immunol 1991; 132(1): 256.
10. Howell CD, Yoder TY, Vierling JM. Suppressor function of liver mononuclear cells isolated during murine chronic graft-vs-host disease. II. Role of prostaglandins and interferon-gamma. Cell Immunol 1992; 140(1): 54.
11. Howell CD, Li J, Roper E, Kotzin BL. Biased liver T cell receptor V beta repertoire in a murine graft-versus-host disease model. J Immunol 1995; 155(5): 2350.
12. Howell CD, De Victor D, Li J, Stephens J, Giorno RC. Liver T cell subsets and adhesion molecules in murine graft-versus-host disease. Bone Marrow Transplant 1995; 16(1): 139.
13. Korngold R, Sprent J. Variable capacity of L3T4+ T cells to cause lethal graft-versus-host disease across minor histocompatibility barriers in mice. J Exp Med 1987; 165(6): 1552.
14. Claman HN, Jaffee BD, Huff JC, Clark RA. Chronic graft-versus-host disease as a model for scleroderma. II. Mast cell depletion with deposition of immunoglobulins in the skin and fibrosis. Cell Immunol 1985; 94(1): 73.
15. Claman HN, Spiegelberg HL. Immunoglobulin dysregulation in murine graft-vs-host disease: a hyper-IgE syndrome. Clin Immunol Immunopathol 1990; 56(1): 46.
16. Claman HN. Graft-versus-host disease and animal models for scleroderma. Curr Opin Rheumatol 1990; 2(6): 929.
17. Hamilton BL. L3T4-positive T cells participate in the induction of graft-vs-host disease in response to minor histocompatibility antigens. J Immunol 1987; 139(8): 2511.
18. Dialynas DP, Quan ZS, Wall KA, et al. Characterization of the murine T cell surface molecule, designated L3T4, identified by monoclonal antibody GK1.5: similarity of L3T4 to the human Leu-3/T4 molecule. J Immunol 1983; 131(5): 2445.
19. Sarmiento M, Glasebrook AL, Fitch FW. IgG or IgM monoclonal antibodies reactive with different determinants on the molecular complex bearing Lyt 2 antigen block T cell-mediated cytolysis in the absence of complement. J Immunol 1980; 125(6): 2665.
20. Vierling JM, Ruderman WB, Jaffee BD, Fennell RH Jr, Claman HN. Hepatic lesions in murine chronic graft-versus-host disease to minor histocompatibility antigens. A reproducible model of nonsuppurative destructive cholangitis. Transplantation 1989; 48(4): 717.
21. Ozdemirli M, el-Khatib M, Bastiani L, Akdeniz H, Kuchroo V, Ju ST. The cytotoxic process of CD4 Th1 clones. J Immunol 1992; 149(6): 1889.
22. Ju ST. Distinct pathways of CD4 and CD8 cells induce rapid target DNA fragmentation. J Immunol 1991; 146(3): 812.
23. Stalder T, Hahn S, Erb P. Fas antigen is the major target molecule for CD4+ T cell-mediated cytotoxicity. J Immunol 1994; 152(3): 1127.
24. Blazar Br, Taylor PA, Vallera DA. In vivo or in vitro anti-CD3 epsilon chain monoclonal antibody therapy for the prevention of lethal murine graft-versus-host disease across the major histocompatibility barrier in mice. J Immunol 1994; 152(7): 3665.
25. Truitt RL, Atasoylu AA. Contribution of CD4+ and CD8+ T cells to graft-versus-host disease and graft-versus-leukemia reactivity after transplantation of MHC-compatible bone marrow. Bone Marrow Transplant 1991; 8(1): 51.
26. Berger M, Wettstein PJ, Korngold R. T cell subsets involved in lethal graft-versus-host disease directed to immunodominant minor histocompatibility antigens. Transplantation 1994; 57(7): 1095.
27. Cobbold S, Waldmann H. Skin allograft rejection by L3/T4+ and Lyt-2+ T cell subsets [published erratum appears in Transplantation 1986; 42(3): 332]. Transplantation 1986; 41(5): 634.
28. Roopenian DC, Anderson PS. Adoptive immunity in immunedeficient scid/scid mice. I. Differential requirements of naive and primed lymphocytes for CD4+ T cells during rejection of minor histocompatibility antigen-disparate skin grafts. Transplantation 1988; 46(6): 899.
29. Roopenian DC, Davis AP. Responses against antigens encoded by the H-3 histocompatibility locus: antigens stimulating class I MHC- and class II MHC-restricted T cells are encoded by separate genes. Immunogenetics 1989; 30(5): 335.
30. Wettstein PJ, Colombo MP. Immunodominance in the T cell response to multiple non-H-2 histocompatibility antigens. IV. Partial tissue distribution and mapping of immunodominant antigens. J Immunol 1987; 139(7): 2166.
31. Wettstein PJ. Immunodominance in the T-cell response to multiple non-H-2 histocompatibility antigens. II. Observation of a hierarchy among dominant antigens. Immunogenetics 1986; 24(1): 24.
32. Wettstein PJ, van Bleek GM, Nathenson SG. Differential binding of a minor histocompatibility antigen peptide to H-2 class I molecules correlates with immune responsiveness. J Immunol 1993; 150(7): 2753.
33. Heath WR, Kjer-Nielsen L, Hoffmann MW. Avidity for antigen can influence the helper dependence of CD8+ T lymphocytes. J Immunol 1993; 151(11): 5993.
34. Heeg K, Steeg C, Hardt C, Wagner H. Identification of interleukin 2-producing T helper cells within murine Lyt-2+ T lymphocytes: frequency, specificity and clonal segregation from Lyt-2+ precursors of cytotoxic T lymphocytes. Eur J Immunol 1987; 17(2): 229.
35. Wettstein PJ, Korngold R. T cell subsets required for in vivo and in vitro responses to single and multiple minor histocompatibility antigens. Transplantation 1992; 54(2): 296.