ATP activates a cation conductance and Ca2+-dependent Cl- conductance in Hensen cells of guinea pig cochlea

American Journal of Physiology

Volumn 271, Issue 6 PART 1, 1996, Pages

  Sugasawa, Masashi ^a   Erostegui, Carlos ^a   Blanchet, Christophe ^b   Dulon, Didier ^a  

^a INSERM   (France)

^b UNIVERSITÉ DE BORDEAUX   (France)

Author keywords

Calcium activated chloride conductance; P2 purinoceptors; Supporting cells

Indexed keywords

ADENOSINE TRIPHOSPHATE; CALCIUM ION; CHLORIDE ION; ETHYLENE GLYCOL 1,2 BIS(2 AMINOPHENYL) ETHER N,N,N',N' TETRAACETIC ACID; GLUCONATE POTASSIUM; INDO 1; IONOMYCIN; PURINE P2 RECEPTOR; SURAMIN;

ANIMAL CELL; APICAL MEMBRANE; ARTICLE; CALCIUM CELL LEVEL; CALCIUM TRANSPORT; CELL ISOLATION; CELL MEMBRANE STEADY POTENTIAL; CELL STIMULATION; CHLORIDE CONDUCTANCE; COCHLEA; CONTROLLED STUDY; CORTI ORGAN; FLUORESCENCE; GUINEA PIG; NONHUMAN; PATCH CLAMP; PRIORITY JOURNAL;

ADENOSINE TRIPHOSPHATE; ANIMALS; CALCIUM; CHLORIDE CHANNELS; CHLORIDES; COCHLEA; GUINEA PIGS; ION TRANSPORT; PATCH-CLAMP TECHNIQUES;

EID: 0030460581     PISSN: 00029513     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpcell.1996.271.6.c1817     Document Type: Article

References (35)

1. Artalejo, A. O., and J. Garcia-Sancho. Mobilization of intracellular calcium by extracellular ATP and by calcium ionophores in the Ehrlich ascites-tumor cells. Biochim. Biophys. Acta 941: 48-54, 1988.
2. Ashmore, J. F., and E. J. Balme. Chloride channels in the apical membrane of isolated Hensen cells of the guinea-pig cochlea (Abstract). J. Physiol. Lond. 401: 97P, 1988.
3. Ashmore, J. F., and H. Ohmori. Control of intracellular calcium by ATP in isolated outer hair cells of the guinea-pig cochlea. J. Physiol. Lond. 428: 109-131, 1990.
4. Barnard, E. A., G. Burnstock, and T. E. Webb. G protein-coupled receptors for ATP and other nucleotides: a new receptor family. Trends Pharmacol. Sci. 15: 67-70, 1994.
5. Bosher, S. K., and R. L. Warren. Very low calcium content of cochlear endolymph, an extracellular fluid. Nature Lond. 273: 377-378, 1978.
6. Brake, A. J., M. J. Wagenbach, and D. Jullius. New structural motif for ligand-gated ion channels defined by an ionotropic ATP receptor. Nature Lond. 371: 519-523, 1994
7. Burnstock, G. Abasis for distinguishing two types of purinergic receptors. In: Cell Membrane Receptors for Drugs and Hormones: A Multidisciplinary Approach, edited by R. W. Straub and L. Bolis. New York: Raven, 1978, p. 107-118.
8. 2-purinergic receptors for extracellular ATP and other nucleotides. Am. J. Physiol. 265 (Cell Physiol. 34): C577-C606, 1993.
9. 2+ signals generated by extracellular nucleotides in supporting cells of the organ of Corti. Cell Calcium 14: 245-254, 1993.
10. 2+ in cochlear inner hair cells. Neuroreport 2: 69-72, 1991.
11. 2+ chelators. Pfluegers Arch. 430: 365-373, 1995.
12. Dulon, D., G. Zajic, and J. Schacht. Increasing intracellular free calcium induces circumferential contractions in isolated outer hair cells. J. Neurosci. 10: 1388-1397, 1990.
13. Fredholm, B. B., M. P. Abbracchio, G. Burnstock, J. W. Daly, T. K. Harden, K. A. Jacobson, P. Leff, and M. Williams. Nomenclature and classification of purinoceptors: a report from the IUPHAR Subcommittee. Pharmacol. Rev. 46: 143-156, 1994.
14. Housley, G. D., D. Greenwood, and J. F. Ashmore. Localization of cholinergic and purinergic receptors on outer hair cells from guinea-pig cochlea. Proc. R. Soc. Lond. B Biol. Sci. 249: 265-273, 1992.
15. Housley, G. D., B. J. Connor, and N. P. Raybould. Purinergic modulation of outer hair cell motility. In: Active Hearing, edited by A. Flock, D. Ottoson, and M. Ulfendahl. Amsterdam: Elsevier, 1995, p. 221-238.
16. Ikeda, K., and T. Morizono. Electrochemical aspects of cations in the cochlear hair cell of the chinchilla: a cellular model of the ion movement. Eur. Arch. Oto-Rhino-Laryngol. 247: 43-47, 1990.
17. Kimura, R. S. The ultrastructure of the organ of Corti. Int. Rev. Cytol. 42: 173-222, 1975.
18. Kolston, P. J., and J. F. Ashmore. Action of ATP on isolated Hensen cells of guinea-pig cochlea investigated by calcium imaging and whole-cell recording (Abstract). J. Physiol. Lond. 446: 389P, 1992.
19. Kujawa, S. G., C. Erostegui, M. Fallon, J. Crist, and R. P. Bobbin. Effects of adenosine 5′-triphosphate and related agonists on cochlear function. Hear. Res. 76: 87-100, 1994.
20. Liu, J., K. Kozakura, and D. C. Marcus. Evidence for purinergic receptors in vestibular dark cell and stria marginal cell epithelia of the gerbil. Auditory Neurosci. 1: 331-340, 1995.
21. Mockett, B. G., G. D. Housley, and P. R. Thorne. Fluorescence imaging of extracellular purinergic receptor sites and putative ecto-ATPases sites on isolated cochlear hair cells. J. Neurosci. 14: 6992-7007, 1994.
22. Munoz, D. J. B., P. R. Thorne, G. D. Housley, T. E. Billet, and J. M. Battersby. Extracellular adenosine 5′-triphosphate (ATP) in the endolymphatic compartment influences cochlear function. Hear. Res. 90: 119-125, 1995.
23. Nakagawa, T., N. Akaike, T. Kimituki, S. Komune, and T. Arima. ATP-induced current in isolated outer hair cells of guinea pig cochlea. J. Neurophysiol. 63: 1068-1074, 1990.
24. 2+] increases in isolated cochlear outer hair cells. Involved receptor and channel mechanisms. Hear. Res. 73: 27-34, 1994.
25. Oesterle, E. C., and P. Dallos. Intracellular recordings from supporting cells in the guinea-pig cochlea: AC potentials. J. Acoust. Soc. Am. 86: 1013-1032, 1989.
26. Salt, A. N, and T. Konishi. The cochlear fluids: perilymph and endolymph. In: Neurobiology of Hearing: The Cochlea, edited by R. A. Altshuler, D. W. Huffman, and R. P. Bobbin. New York: Raven, 1986, p. 109-122.
27. Santos-Sacchi, J. Electrical coupling differs in the in vitro and in vivo organ of Corti. Hear. Res. 25: 227-232, 1987.
28. Santos-Sacchi, J. Isolated supporting cells from the organ of Corti: some whole cell electrical characteristics and estimates of gap junctional conductance. Hear. Res. 52: 89-98, 1991.
29. 2+. Hear. Res. 80: 21-24, 1994.
30. Sugasawa, M., C. Erostegui, C. Blanchet, and D. Dulon. ATP activates non-selective cation channels and calcium release in inner hair cells of the guinea-pig cochlea. J. Physiol. Lond. 491: 707-718, 1996.
31. Sunose, H., K. Ikeda, Y. Saito, A. Nishiyama, and T. Takasaka. Nonselective cation and Cl channels in luminal membrane of the marginal cell. Am. J. Physiol. 265 (Cell Physiol. 34): C72-C78, 1993.
32. - channels in apical membrane of marginal cells of stria vascularis. Hear. Res. 61: 86-96, 1992.
33. Thalmann, R., A. N. Salt, and J. DeMott. Endolymph volume regulation: possible mechanisms. In: Second International Symposium on Ménière Disease, edited by J. B. Nadol, Jr. Berkeley, CA: Kugler & Ghedini, 1989, p. 55-60.
34. 2x receptor for extracellular ATP. Nature Lond. 371: 516-519, 1994.
35. Webb, T. E., J. Simon, B. J. Krishek, A. N. Bateson, T. G. Smart, B. F. Kiag, G. Burnstock, and E. A Barnard. Cloning and functional expression of a brain G-protein-coupled ATP receptor. FEBS Lett. 324, 219-225, 1993.