Synergy between tumor necrosis factor α and interleukin 1β in inducing transcriptional down-regulation of muscarinic M2 receptor gene expression: Involvement of protein kinase A and ceramide pathways

Journal of Biological Chemistry

Volumn 271, Issue 51, 1996, Pages 32586-32592

  Haddad, El Bdaoui ^a   Rousell, Jonathan ^a   Lindsay, Mark A ^a   Barnes, Peter J ^a  

^a NATIONAL HEART AND LUNG INSTITUTE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

2 [1 (3 DIMETHYLAMINOPROPYL) 3 INDOLYL] 3 (3 INDOLYL)MALEIMIDE; CERAMIDE; CYCLIC AMP DEPENDENT PROTEIN KINASE; INTERLEUKIN 1BETA; MITOGEN ACTIVATED PROTEIN KINASE; MUSCARINIC M2 RECEPTOR; N (2 METHYLAMINOETHYL) 5 ISOQUINOLINESULFONAMIDE; TUMOR NECROSIS FACTOR ALPHA;

AMINO TERMINAL SEQUENCE; ARTICLE; GENE EXPRESSION REGULATION; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; INFLAMMATION; INTERNALIZATION; NORTHERN BLOTTING; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN SYNTHESIS; RECEPTOR BINDING; RECEPTOR DOWN REGULATION; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION;

CA(2+)-CALMODULIN DEPENDENT PROTEIN KINASE; CELLS, CULTURED; CERAMIDES; CYCLIC AMP-DEPENDENT PROTEIN KINASES; CYCLOHEXIMIDE; DOWN-REGULATION; GENE EXPRESSION REGULATION; HUMANS; INTERLEUKIN-1; PROTEIN KINASE C; RECEPTORS, MUSCARINIC; RNA, MESSENGER; SIGNAL TRANSDUCTION; TRANSCRIPTION, GENETIC; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0030459813     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.271.51.32586     Document Type: Article

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