Mammalian homologues of yeast vacuolar protein sorting (vps) genes implicated in Golgi-to-lysosome trafficking

Gene

Volumn 183, Issue 1-2, 1996, Pages 7-14

  Pevsner, Jonathan ^a,b   Hsu, Shu Chan ^a   Hyde, Peter S ^a   Scheller, Richard H ^a  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

n sec1; Secretion; Syntaxin; Vacuole; Vesicles

Indexed keywords

ARTICLE; BRAIN; GOLGI COMPLEX; HUMAN; INTRACELLULAR TRANSPORT; KIDNEY; LIVER; LUNG; LYSOSOME; MAMMAL; MULTIGENE FAMILY; NONHUMAN; NORTHERN BLOTTING; PHYLOGENY; PRIORITY JOURNAL; PROTEIN TARGETING; PROTEIN TRANSPORT; SEQUENCE HOMOLOGY; SKELETAL MUSCLE; SPLEEN; SYNAPSE VESICLE; TESTIS;

ADULT; AMINO ACID SEQUENCE; ANIMALS; CARRIER PROTEINS; CLONING, MOLECULAR; DNA, COMPLEMENTARY; FUNGAL PROTEINS; GENE EXPRESSION REGULATION; GOLGI APPARATUS; HUMANS; LYSOSOMES; MALE; MEMBRANE PROTEINS; MOLECULAR SEQUENCE DATA; MUNC18 PROTEINS; NERVE TISSUE PROTEINS; ORGAN SPECIFICITY; PHYLOGENY; PROTEIN BINDING; QA-SNARE PROTEINS; RATS; RNA, MESSENGER; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; SEQUENCE ANALYSIS, DNA; SEQUENCE HOMOLOGY, AMINO ACID; SYNTAXIN 1; VACUOLES; VESICULAR TRANSPORT PROTEINS;

MAMMALIA;

EID: 0030459086     PISSN: 03781119     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-1119(96)00367-8     Document Type: Article

References (30)

1. Aalto, M.K., Ruohonen, L., Hosono, K. and Keränen, S. (1991) Cloning and sequencing of the yeast Saccharomyces cerevisiae SEC1 gene localized on chromosome IV. Yeast 7, 643-650.
2. Aalto, M., Keränen, S. and Ronne, H. (1992) A family of proteins involved in intracellular transport. Cell 68, 181-182.
3. Aalto, M.K., Ronne, H. and Keränen, S. (1993) Yeast syntaxins Sso1p and Sso2p belong to a family of related membrane proteins that function in vesicular transport. EMBO J. 12, 4095-4104.
4. Bankaitis, V.A., Johnson, L.M. and Emr, S.D. (1986) Isolation of yeast mutants defective in protein targeting to the vacuole. Proc. Natl. Acad. Sci. USA 83, 9075-9079.
5. Banta, L.M., Vida, T.A., Herman, P.K. and Emr, S.D. (1990) Characterization of yeast Vps33p, a protein required for vacuolar protein sorting and vacuole biogenesis. Mol. Cell. Biol. 10, 4638-4649.
6. Cataldo, A.M, Hamilton, D.J. and Nixon, R.A. (1994) Lysosomal abnormalities in degenerating neurons link neuronal compromise to senile plaque development in Alzheimer disease. Brain Res. 640, 68-80.
7. Cowles, C.R., Emr, S.D. and Horazdovsky, B.F. (1994) Mutations in the VPS45 gene, a SEC1 homologue, result in vacuolar protein sorting defects and accumulation of membrane vesicles. J. Cell Sci. 107, 3449-3459.
8. Czelusniak, J., Goodman, M., Moncrief, N.D. and Kehoe, S.M. (1990) Maximum parsimony approach to construction of evolutionary trees from aligned homologous sequences. Methods Enzymol. 183, 601-615.
9. Dascher, C., Ossig, R., Gallwitz, D. and Schmitt, H.D. (1991) Identification and structure of four yeast genes (SLY) that are able to supress the functional loss of YPT1, a member of the RAS superfamily. Mol. Cell. Biol. 11, 872-885.
10. Garcia, E.P., Gatti, E., Butler, M., Burton, J, and de Camilli, P. (1994) A rat brain Sec1 homologue related to Rop and UNC18 interacts with syntaxin. Proc. Natl. Acad. Sci. USA 91, 2003-2007.
11. Garcia, E.P., McPherson, P.S., Chilcote, T.J., Takei, K. and De Camilli, P. (1995) rbSec1A and B colocalize with syntaxin 1 and SNAP-25 throughout the axon, but are not in a stable complex with syntaxin. J. Cell Biol. 129, 105-120.
12. Hata, Y. and Südhof, T.C. (1995) A novel ubiquitous form of Munc-18 interacts with multiple syntaxins. J. Biol. Chem. 270, 13022-13028.
13. Hata, Y., Slaughter, C.A. and Südhof, T.C. (1993) Synaptic vesicle fusion complex contains unc-18 homologue bound to syntaxin. Nature 366, 347-351.
14. Hillis, D.M. and Bull, J.J. (1993) An empirical test of bootstrapping as a method for assessing confidence in phylogenetic analysis. Syst. Biol. 42, 182-192.
15. Hodel, A., Schäfer, T., Gerosa, D. and Burger, M.M. (1994) In chromaffin cells, the mammalian Sec1p homologue is a syntaxin 1A-binding protein associated with chromaffin granules. J. Biol. Chem. 269, 8623-8626.
16. Katagiri, H., Terasaki, J., Murata, T., Ishihara, H., Ogihara, T., Inukai, K., Fukushima, Y., Anai, M., Kikuchi, M., Miyazaki, J.-I., Yazaki, Y. and Oka, Y. (1995) A novel isoform of syntaxin-binding protein homologous to yeast Sec1 expressed ubiquitously in mammalian cells. J. Biol. Chem. 270, 4963-4966.
17. Kozak, M. (1989) The scanning model for translation: an update. J. Cell Biol. 108, 229-241.
18. Mayer, R.J., Landen, M., Laszlo, L., Lennox, G. and Lowe, J. (1992) Protein processing in lysosomes: the new therapeutic target in neurodegenerative disease. Lancet 340, 156-159.
19. Nothwehr, S.F. and Stevens, T.H. (1994) Sorting of membrane proteins in the yeast secretory pathway. J. Biol. Chem. 269, 10185-10188.
20. Novick, P., Field, C. and Schekman, R. (1980) Identification of 23 complementation groups required for post-translational events in the yeast secretory pathway. Cell 21, 205-215.
21. Ossig, R., Dascher, C., Trepte, H.-H., Schmitt, H.D. and Gallwitz, D. (1991) The yeast SLY gene products, suppressors of defects in the essential GTP-binding Ypt1 protein, may act in endoplasmic reticulum-to-Golgi transport Pevsner, J., Hsu, S.-C., Braun, J.E.A., Calakos, N., Ting, A.E., Bennett, M.K. and Scheller, R.H. (1994a) Specificity and regulation of a synaptic vesicle docking complex. Neuron 13, 353-361.
22. Pevsner, J., Hsu, S.-C. and Scheller, R.H. (1994b) n-Sec1: A neural-specific syntaxin-binding protein. Proc. Natl. Acad. Sci. USA 91, 1445-1449.
23. Piper, R.C., Whitters, E.A. and Stevens, T.H. (1994) Yeast Vps45p is a Sec1p-like protein required for the consumption of vacuole-targeted, post-Golgi transport vesicles. Eur. J. Cell Biol. 65, 305-318.
24. Proudfoot, N. (1991) Poly(A) signals. Cell 64, 671-674.
25. Raymond, C.K., Howald-Stevenson, I., Vater, C.A. and Stevens, T.H. (1992) Morphological classification of the yeast vacuolar protein sorting mutants: Evidence for a prevacuolar compartment in Class E vps mutants. Mol. Biol. Cell 3, 1389-1402.
26. Robinson, J.S., Klionsky, D.J., Banta, L.M. and Emr, S.D. (1988) Protein sorting in Saccharomyces cerevisiae: Isolation of mutants defective in the delivery and processing of multiple vacuolar hydrolases. Mol. Cell. Biol. 8, 4936-4948.
27. Rothman, J.H. and Stevens, T.H. (1986) Protein sorting in yeast: mutants defective in vacuole biogenesis mislocalize vacuolar proteins into the late secretory pathway. Cell 47, 1041-1051.
28. Tellam, J.T., McIntosh, S. and James, D.E. (1995) Molecular identification of two novel Munc-18 isoforms expressed in non-neuronal tissues. J. Biol. Chem. 270, 5857-5863.
29. Wada, Y., Kitamoto, K., Kanbe, T., Tanaka, K. and Anraku, Y. (1990) The SLP1 gene of Saccaromyces cervisiae is essential for vauolar morphogenesis and function. Mol. Cell. Biol. 10, 2214-2223.
30. Zhao, H., Boissy, Y.L., Abdel-Malek, Z., King, R.A., Nordlund, J.J. and Boissy, R.E. (1994) On the analysis of the pathophysiology of Chediak-Higashi syndrome. Lab. Invest. 71, 25-34.