Nonsyndromic X-linked mental retardation: Review and mapping of MRX29 to Xp21

Clinical Genetics

Volumn 50, Issue 4, 1996, Pages 176-183

  Hane B ^a   Schroer, R J ^a   Arena, J F ^b   Lubs, H A ^b   Schwartz, C E ^a   Stevenson, R E ^a  

^a GREENWOOD GENETIC CENTER   (United States)

^b UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

Author keywords

Linkage analysis; Mental retardation; MRX29; X chromosome

Indexed keywords

ADULT; ARTICLE; CHROMOSOME XP; CLINICAL ARTICLE; GENE LOCATION; GENE LOCUS; GENETIC LINKAGE; HUMAN; MALE; MENTAL DEFICIENCY; PRIORITY JOURNAL;

EID: 0030458716     PISSN: 00099163     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1399-0004.1996.tb02622.x     Document Type: Article

References (49)

1. Arveiler B, Alembik Y, Hanauer A, Jacobs P, Tranebjaerg L, Mikkelsen M, Puissant H, Piet LL, Mandel JL. Linkage analysis suggests at least two loci for X-linked non-specific mental retardation. Am J Med Genet 1988: 30: 473-483.
2. Birch HG, Richardson SA, Baird D, Horobin G, Illsley R. Mental subnormality in the community; a clinical and epidemiologic study. Baltimore: Williams & Wilkins, 1970.
3. Donnelly AJ, Choo KHA, Kozman HM, Gedeon AK, Danks DM, Mulley JC. Regional localisation of a non-specific X-linked mental retardation gene (MRX 19) to Xp22. Am J Med Genet 1994: 51: 581-585.
4. Feinberg AP, Vogelstein B. A Technique for radiolabeling DNA restriction endonuclease fragments to high specific activity. Anal Biochem 1983: 132: 6-13.
5. Gedeon AK, Glass IA, Connor JM, Mulley JC. Genetic localisation of MRX27 to Xq24-26 defines the sixth discrete gene for non-specific X-linked mental retardation. Am J Med Genet 1996 (in press).
6. Gedeon A, Kerr B, Mulley J, Turner G. Localisation of the MRX3 gene for nonspecific X-linked mental retardation. J Med Genet 1991: 28: 372-377.
7. Gedeon A, Kerr B, Mulley J, Turner G. Pericentromeric genes for non-specific X-linked mental retardation (MRX). Am J Med Genet 1994: 51: 553-164.
8. Gendrot C, Ronce N, Toutain A, Moizard M-P, Müh J-P, Raynaud M, Dourlens J, Briault S, Moraine C. X-linked mental retardation exhibiting linkage to DXS255 and PGKP1: a new MRX family (MRX14) with localization in the pericentromeric region. Clin Genet 1994: 45: 145-153.
9. Glass IA, White EM, Pope MJ, Pirrit LA, Cockburn F, Connor JM. Linkage analysis in a large family with nonspecific X-linked retardation. Am J Med Genet 1991: 38: 240-243.
10. Herbst DS, Miller JR. Non-specific X-linked mental retardation 11: the frequency in British Columbia. Am J Med Genet 1980: 7: 461-469.
11. Hu L-J, Blumenfeld-Heyberger S, Hanauer A, Weissenbach J, Mandel J-L. Nonspecific X-linked mental retardation: linkage analysis in MRX2 and MRX4 families revisited. Am J Med Genet 1994: 51: 569-574.
12. Jedele KB, Michels W, Schaid DJ, Schowalter, Thibodeau SN. Linkage of nonspecific X-linked mental retardation to Xq21.31. Am J Med Genet 1992: 43: 436-442.
13. Kerr B, Turner G, Mulley J, Gedeon A, Partington M. Non-specific X-linked mental retardation. J Med Genet 1991: 28: 378-382.
14. Kerr B, Gedeon A, Mulley J, Turner G. Localization of non-specific X-linked mental retardation genes. Am J Med Genet 1992: 43: 392-401.
15. Knight SJL, Voelckel MA, Hirst MC, Flannery AV, Moncla A, Davies KE. Triplet repeat expansion at the FRAXE locus and X-linked mild mental handicap. Am J Hum Genet 1994: 55: 81-86.
16. Kondo I, Tsukamoto K, Nilkawa N, Okano K, Kanazawa I, Hupkes PK, A new form of X-linked mental retardation (XLMR) linked to DXS369(RN1). Cytogenet Cell Genet 1991: 58: 2071.
17. Kozak L, Chiurazzi P, Genuardi M, Pomponi MG, Zollino M, Neri G. Mapping of a gene for non-specific X-linked mental retardation: evidence for linkage to chromosomal region Xp21.1-Xp22.3. J Med Genet 1993: 30: 866-869.
18. Lathrop GM, Lalouel JM. Easy calculations of lod scores and genetic risks on small computers. Am J Hum Genet 1984: 36: 460-465.
19. Lathrop GM, Lalouel JM, Julier C, Ott J. Multilocus linkage analysis in humans: detection of linkage and estimation of recombination. Am J Hum Genet 1985: 37: 482-498.
20. Lazzarine A, Stenroos ES, Lehner T, McKoy V, Gold B, Mc-Cormack MK, Reis CS, Ott J, Johnson WG. Short tandem repeat polymorphism linkage studies in a new family with X-linked mental retardation (MRX20). Am J Med Genet 1995: 57: 552-557.
21. Lehrke RG. X-linked mental retardation and verbal disability. BD: OAS 1974: X(1): 1-100.
22. Lewis EO. Report on an investigation into the incidence of mental deficiency in six areas, 1925-1927. London: His Majesty's Stationery Office, 1929.
23. Litt M, Hauge X, Sharma V. Shadow bands seen when typing polymorphic dinucleotides repeats: some causes and cures. Biotechniques 1993: 15: 280-284.
24. Martinez F, Gal A, Palau F, Prieto F. Localization of a gene for X-linked nonspecific mental retardation (MRX24) in Xp22.2-p22.3. Am J Med Genet 1995: 55: 387-390.
25. Moraine C, Dessay B, Toutain A, Briault S Gendrot C, Ronce N. X-linked mental retardation: linkage results in five unrelated families. Am J Hum Genet 1994: 55: 3, A1141.
26. Mulley JC, Kerr B, Stevenson R, Lubs H. Nomenclature guidelines for X-linked mental retardation. Am J Med Genet 1992: 43: 383-391.
27. Mulley JC, Yu S, Loesch DZ, Donnelly A, Gedeon AK, Carbonell P, Lopez I, Glover G, Gabarron I, Yu PWL, Baker E, Haan EA, Hockey A, Knight SJL, Davies KE, Richards RI, Sutherland GR. FRAXE and mental retardation. J Med Genet 1995: 32: 162-169.
28. Neri G, Chiurazzi P, Arena JF, Lubs HA. XLMR genes: update 1994. Am J Med Genet 1994: 51: 542-549.
29. Nordstrom A-M, Penttinen M, von Koskull H. Linkage to Xq28 in a family with nonspecific X-linked mental retardation. Hum Genet 1992: 90: 263-266.
30. Passos-Bueno MR, Byth BC, Rosenberg S, Takata RI, Bakker E, Beggs AH, Pavanello RC, Vainzof M, Davies KE, Zatz M. Severe nonspecific X-linked mental retardation caused by a proximally Xp located gene: intragenic heterogeneity or a new form of X-linked mental retardation? Am J Med Genet 1993: 46: 172-175.
31. Penrose LS. A clinical and genetic study of 1,280 cases of mental defect. Special Rep Ser 229. London: Medical Research Council, 1939.
32. Proops R, Mayer M, Jacobs PA. A study of mental retardation in children in the island of Hawaii. Clin Genet 1983: 23: 81-96.
33. Samanns C, Albrecht R, Neugebauer M, Neri G, Gal A. Gene for non-specific X-linked mental retardation maps in the pericentromeric region. Am J Med Genet 1991: 38: 224-227.
34. Schwartz CE. Invited editorial: X-linked mental retardation: in pursuit of a gene map. Am J Hum Genet 1993: 52: 1025-1031.
35. Schwartz CE, May M, Huang T, Ledbetter D, Anderson G, Barker DF, Lubs HA, Arena F, Stevenson RE. MRX8: an X-linked mental retardation condition with linkage to Xq21. Am J Med Genet 1992: 43: 467-474.
36. Schwartz CE, McNally E, Leinward L, Skolnick MH. Linkage of a myosin heavy chain locus to an anonymous single copy locus (D17S1) at 17p13. Cytogenet Cell Genet 1986: 43: 117-120.
37. Schwartz CE, Ulmer J, Brown A, Pancoast I, Goodman HO, Stevenson RE. Allan Herndon syndrome. II. Linkage to DNA markers in Xq21. Am J Hum Genet 1990: 47: 454-458.
38. Snyder RD, Robinson A. Recessive sex-linked mental retardation in the absence of other recognizable abnormalities: report of a family. Clin Pediatr 1969: 8: 669-674.
39. Stevenson RE, Goodman HO, Schwartz CE, Simensen RJ, McLean WE Jr, Herndon CN. Allan-Herndon syndrome. I. Clinical studies. Am J Hum Genet 1990: 47: 446-453.
40. Suthers GK, Turner G, Mulley JC. A non-syndromal form of X-linked mental retardation (XLMR) is linked to DXS14. Am J Med Genet 1988: 30: 485-491.
41. Turner G, Turner B. X-linked mental retardation. J Med Genet, 1974: 11: 109-113.
42. Turner G, Turner B, Collins E. X-linked mental retardation without physical abnormality: Renpenning's syndrome. Devel Med Child Neurol 1971: 13: 71-78.
43. Watty A, Prieto F, Beneyto M, Neugebauer M, Gal A. Gene localization in a family with X-linked syndromal mental retardation (Prieto Syndrome). Am J Med Genet 1991: 38: 234-239.
44. Willard HF, Cremers F, Mandel JL, Monaco AP, Nelson DL, Schlessinger D. Report of the fifth international workshop on human X-chromosome mapping 1994. Cytogenet Cell Genet 1994: 67: 295-358.
45. Willems P, Vits L, Buntinx I, Reymaekers P, Van Broeckhoven C, Ceulemans B. Localization of a gene responsible for non-specific mental retardation (MRX9) to the pericentromeric region of the X-chromosome. Genomics 1993: 18: 290-294.
46. Wilson GN, Richards CS, Katz K, Brookshire GS. Non-specific X-linked mental retardation with aphasia exhibiting genetic linkage to chromosomal region Xp11. J Med Genet 1992: 29: 629-634.
47. Wing L. Severely retarded children in a London area: prevalence and provision of services. Psychol Med 1971: 1: 405-415.
48. Yarbrough KM, Howard-Peebles PN. X-linked nonspecific mental retardation: report of a large kindred. Clin Genet 1976: 9: 125-130.
49. Zanaria E, Muscatelli F, Bardoni B, Strom TM, Guloli S, Guo W, Lalli E, Moser C, Walker AP, McCabe ERB, Meitinger T, Monaco AP, Sassone-Corsi P, Camerino G. An unusual member of the nuclear hormone receptor superfamily responsible for X-linked adrenal hypoplasia congenita. Nature 1994: 372: 635-641.