메뉴 건너뛰기




Volumn 36, Issue , 1996, Pages 165-180

rTS gene expression is associated with altered cell sensitivity to thymidylate synthase inhibitors

Author keywords

[No Author keywords available]

Indexed keywords

2 [5 [[(1,2 DIHYDRO 3 METHYL 1 OXOBENZO[F]QUINAZOLIN 9 YL)METHYL]AMINO] 1 OXO 2 ISOINDOLINYL]GLUTARIC ACID; 5-FLUOROURIDINE; ANTINEOPLASTIC AGENT; COMPLEMENTARY RNA; DRUG DERIVATIVE; ENZYME INHIBITOR; FLOXURIDINE; FLUOROURACIL; MESSENGER RNA; METESIND GLUCURONATE; THYMIDYLATE SYNTHASE; THYMIDYLATE SYNTHASE INHIBITOR; TOMUDEX; TRIFLURIDINE; URIDINE;

EID: 0030458182     PISSN: 00652571     EISSN: None     Source Type: Book Series    
DOI: 10.1016/0065-2571(95)00009-7     Document Type: Conference Paper
Times cited : (19)

References (37)
  • 1
    • 0028212113 scopus 로고
    • Posttranscriptional regulation of thymidylate synthase gene expression
    • L. F. JOHNSON, Posttranscriptional regulation of thymidylate synthase gene expression, J. Cell. Biochem. 54, 387-392 (1994).
    • (1994) J. Cell. Biochem. , vol.54 , pp. 387-392
    • Johnson, L.F.1
  • 2
    • 0022550099 scopus 로고
    • Levels of thymidylate synthetase during normal culture growth of L1210 cells
    • E. CADMAN and R. HEIMER, Levels of thymidylate synthetase during normal culture growth of L1210 cells, Cancer Res. 46, 1195-1198 (1986).
    • (1986) Cancer Res. , vol.46 , pp. 1195-1198
    • Cadman, E.1    Heimer, R.2
  • 3
    • 0022473119 scopus 로고
    • Cell-cycle-directed regulation of thymidylate synthase messenger RNA in human diploid fibroblasts stimulated to proliferate
    • D. AYUSAWA, K. SHIMIZU, H. KOYAMA, S. KANEDA, K. TAKEISHI and T. SENO, Cell-cycle-directed regulation of thymidylate synthase messenger RNA in human diploid fibroblasts stimulated to proliferate, J. Mol. Biol. 190, 559-567 (1986).
    • (1986) J. Mol. Biol. , vol.190 , pp. 559-567
    • Ayusawa, D.1    Shimizu, K.2    Koyama, H.3    Kaneda, S.4    Takeishi, K.5    Seno, T.6
  • 4
    • 0023664458 scopus 로고
    • Analysis of thymidylate synthase gene amplification and of mRNA levels in the cell cycle
    • A. M. ALI IMAM, P. H. CROSSLEY, A. L. JACKMAN and P. F. R. LITTLE, Analysis of thymidylate synthase gene amplification and of mRNA levels in the cell cycle, J. Biol. Chem. 262, 7368-7373 (1987).
    • (1987) J. Biol. Chem. , vol.262 , pp. 7368-7373
    • Ali Imam, A.M.1    Crossley, P.H.2    Jackman, A.L.3    Little, P.F.R.4
  • 5
    • 0025964105 scopus 로고
    • The 5′-flanking region of the mouse thymidylate synthase gene is necessary but not sufficient for normal regulation in growth-stimulated cells
    • Y. LI, D. LI, K. OSBORN and L. F. JOHNSON, The 5′-flanking region of the mouse thymidylate synthase gene is necessary but not sufficient for normal regulation in growth-stimulated cells, Mol. Cell. Biol. 11, 1023-1029 (1991).
    • (1991) Mol. Cell. Biol. , vol.11 , pp. 1023-1029
    • Li, Y.1    Li, D.2    Osborn, K.3    Johnson, L.F.4
  • 6
    • 0019321438 scopus 로고
    • Cell cycle regulation of thymidylate synthase gene expression in cultured mouse fibroblasts
    • L. G. NAVALGUND, C. ROSSANA, A. J. MUENCH and L. F. JOHNSON, Cell cycle regulation of thymidylate synthase gene expression in cultured mouse fibroblasts, J. Biol. Chem. 255, 7386-7390 (1980).
    • (1980) J. Biol. Chem. , vol.255 , pp. 7386-7390
    • Navalgund, L.G.1    Rossana, C.2    Muench, A.J.3    Johnson, L.F.4
  • 7
    • 0018837498 scopus 로고
    • Regulation of thymidylate synthetase in mouse leukemia cells (L1210)
    • W. RODE, K. J. SCANLON, B. A. MOROSON and J. R. BERTINO, Regulation of thymidylate synthetase in mouse leukemia cells (L1210), J. Biol. Chem. 255, 1305-1311 (1980).
    • (1980) J. Biol. Chem. , vol.255 , pp. 1305-1311
    • Rode, W.1    Scanlon, K.J.2    Moroson, B.A.3    Bertino, J.R.4
  • 8
    • 0015217221 scopus 로고
    • Thymidylate synthetase activity in cultured mammalian cells
    • A. H. CONRAD, Thymidylate synthetase activity in cultured mammalian cells, J. Biol. Chem. 246, 1318-1323 (1971).
    • (1971) J. Biol. Chem. , vol.246 , pp. 1318-1323
    • Conrad, A.H.1
  • 12
    • 0026981078 scopus 로고
    • Quantitation of dihydrofolate reductase and thymidylate synthase mRNAs in vivo and in vitro by polymerase chain reaction
    • B. J. DOLNICK, Z.-G. ZHANG, J. D. HINES and Y. M. RUSTUM, Quantitation of dihydrofolate reductase and thymidylate synthase mRNAs in vivo and in vitro by polymerase chain reaction, Oncol. Res. 4, 65-72 (1992).
    • (1992) Oncol. Res. , vol.4 , pp. 65-72
    • Dolnick, B.J.1    Zhang, Z.-G.2    Hines, J.D.3    Rustum, Y.M.4
  • 13
    • 0024413739 scopus 로고
    • Fluorouracil and high-dose leucovorin in previously treated patients with metastatic breast cancer
    • S. M. SWAIN, M. E. LIPPMAN, E. F. EGAN, J. C. DRAKE, S. M. STEINBERG and C. J. ALLEGRA, Fluorouracil and high-dose leucovorin in previously treated patients with metastatic breast cancer, J. Clin. Oncol. 7, 890-899 (1989).
    • (1989) J. Clin. Oncol. , vol.7 , pp. 890-899
    • Swain, S.M.1    Lippman, M.E.2    Egan, E.F.3    Drake, J.C.4    Steinberg, S.M.5    Allegra, C.J.6
  • 15
    • 0027174556 scopus 로고
    • Cloning and characterization of a naturally occurring antisense RNA to human thymidylate synthase mRNA
    • B. J. DOLNICK, Cloning and characterization of a naturally occurring antisense RNA to human thymidylate synthase mRNA, Nucl. Acids Res. 21, 1747-1752 (1993).
    • (1993) Nucl. Acids Res. , vol.21 , pp. 1747-1752
    • Dolnick, B.J.1
  • 17
    • 0003448569 scopus 로고
    • Cold Spring Harbor Laboratory, Cold Spring Harbor, New York
    • E. HARLOW and D. LANE, pp. 430 in Antibodies: A Laboratory Manual. Cold Spring Harbor Laboratory, Cold Spring Harbor, New York (1988).
    • (1988) Antibodies: A Laboratory Manual , pp. 430
    • Harlow, E.1    Lane, D.2
  • 18
    • 0014949207 scopus 로고
    • Cleavage of structural proteins during the assembly of the head of bacteriophage T4
    • U. K. LAEMMLI, Cleavage of structural proteins during the assembly of the head of bacteriophage T4, Nature 227, 680-685 (1970).
    • (1970) Nature , vol.227 , pp. 680-685
    • Laemmli, U.K.1
  • 19
    • 0018700703 scopus 로고
    • Fluorographic detection of radioactivity in polyacrylamide gels with the water-soluble fluor sodium salicylate
    • J. P. CHAMBERLAIN, Fluorographic detection of radioactivity in polyacrylamide gels with the water-soluble fluor sodium salicylate, Anal. Biochem. 98, 132-135 (1979).
    • (1979) Anal. Biochem. , vol.98 , pp. 132-135
    • Chamberlain, J.P.1
  • 20
    • 0021986402 scopus 로고
    • Effects of 5-fluorouracil on dihydrofolate reductase and dihydofolate reductase mRNA from methotrexate-resistant KB cells
    • B. J. DOLNICK and J. J. PINK, Effects of 5-fluorouracil on dihydrofolate reductase and dihydofolate reductase mRNA from methotrexate-resistant KB cells, J. Biol. Chem. 260, 3006-3014 (1985).
    • (1985) J. Biol. Chem. , vol.260 , pp. 3006-3014
    • Dolnick, B.J.1    Pink, J.J.2
  • 21
    • 0027257259 scopus 로고
    • Quantitative evaluation of intracellular sense: Antisense RNA hybrid duplexes
    • S. J. WANG and B. J. DOLNICK, Quantitative evaluation of intracellular sense: antisense RNA hybrid duplexes, Nucl. Acids Res. 21, 4383-4391 (1993).
    • (1993) Nucl. Acids Res. , vol.21 , pp. 4383-4391
    • Wang, S.J.1    Dolnick, B.J.2
  • 22
    • 0026510868 scopus 로고
    • Enhanced sensitivity to G418 of human KB cells adapted to certain media and sera
    • L. A. HANCHETT, S. J. WANG, R. L. MEEGAN, R. M. BAKER and B. J. DOLNICK, Enhanced sensitivity to G418 of human KB cells adapted to certain media and sera, BioTech. 12, 482-483 (1992).
    • (1992) BioTech. , vol.12 , pp. 482-483
    • Hanchett, L.A.1    Wang, S.J.2    Meegan, R.L.3    Baker, R.M.4    Dolnick, B.J.5
  • 23
    • 0018639079 scopus 로고
    • Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease
    • J. M. CHIRGWIN, A. E. PRZYBYLA, R. J. MacDONALD and W. J. RUTTER, Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease, Biochemistry 18, 5294-5299, 1979.
    • (1979) Biochemistry , vol.18 , pp. 5294-5299
    • Chirgwin, J.M.1    Przybyla, A.E.2    MacDonald, R.J.3    Rutter, W.J.4
  • 26
    • 0024827539 scopus 로고
    • 5-Fluorouracil inhibits dihydrofolate reductase precursor mRNA processing and/or nuclear mRNA stability in methotrexate-resistant KB cells
    • C. L. WILL and B. J. DOLNICK, 5-Fluorouracil inhibits dihydrofolate reductase precursor mRNA processing and/or nuclear mRNA stability in methotrexate-resistant KB cells, J. Biol. Chem. 264, 21413-21421 (1989).
    • (1989) J. Biol. Chem. , vol.264 , pp. 21413-21421
    • Will, C.L.1    Dolnick, B.J.2
  • 27
    • 0029120895 scopus 로고
    • Mechanisms of resistance to N-[5[N-(3,4-dihydro-2-methyl-4-oxoquinazolin-6-ylmethyl)-N-methylamino]-2- thenoyl]-L- glutamic acid (ZD 1694), a folate based thymidylate synthase inhibitor, in the HCT-8 human ileocecal adenocarcinoma cell line
    • K. LU, M.-B. YIN, J. J. McGUIRE, E. BONMASSAR and Y. M. RUSTUM, Mechanisms of resistance to N-[5[N-(3,4-dihydro-2-methyl-4-oxoquinazolin-6-ylmethyl)-N-methylamino]-2- thenoyl]-L- glutamic acid (ZD 1694), a folate based thymidylate synthase inhibitor, in the HCT-8 human ileocecal adenocarcinoma cell line, Biochem. Pharmacol. 50, 391-398 (1995).
    • (1995) Biochem. Pharmacol. , vol.50 , pp. 391-398
    • Lu, K.1    Yin, M.-B.2    McGuire, J.J.3    Bonmassar, E.4    Rustum, Y.M.5
  • 28
    • 0027369455 scopus 로고
    • Studies on the cross resistance of folylpolyglutamate synthetase-deficient, methotrexate-resistant CCRF-CEM human leukemia sublines
    • J. J. McGUIRE, K. J. HEITZMAN, W. H. HAILE, C. A. RUSSELL, D. E. McCLOSKEY and J. R. PIPER, Studies on the cross resistance of folylpolyglutamate synthetase-deficient, methotrexate-resistant CCRF-CEM human leukemia sublines, Advan. Exptl. Med. Biol. 338, 667-670 (1993).
    • (1993) Advan. Exptl. Med. Biol. , vol.338 , pp. 667-670
    • McGuire, J.J.1    Heitzman, K.J.2    Haile, W.H.3    Russell, C.A.4    McCloskey, D.E.5    Piper, J.R.6
  • 30
    • 0026335113 scopus 로고
    • Production and characterization of monoclonal antibodies that localize human thymidylate synthase in the cytoplasm of human cells and tissues
    • P. G. JOHNSTON, C.-M. LIANG, S. HENRY, B. A. CHABNER and C. J. ALLEGRA, Production and characterization of monoclonal antibodies that localize human thymidylate synthase in the cytoplasm of human cells and tissues, Cancer Res. 51, 6668-6676 (1991).
    • (1991) Cancer Res. , vol.51 , pp. 6668-6676
    • Johnston, P.G.1    Liang, C.-M.2    Henry, S.3    Chabner, B.A.4    Allegra, C.J.5
  • 31
    • 0023940788 scopus 로고
    • Gene amplification in cultured cells
    • R. T. SCHIMKE, Gene amplification in cultured cells, J. Biol. Chem. 263, 5989-5992 (1988).
    • (1988) J. Biol. Chem. , vol.263 , pp. 5989-5992
    • Schimke, R.T.1
  • 32
    • 0027480851 scopus 로고
    • Chromosomal reassignment: YACs containing both YES1 and thymidylate synthase map to the short arm of chromosome 18
    • G. A. SILVERMAN, W.-L. KUO, P. TAILLON-MILLER and J. W. GRAY, Chromosomal reassignment: YACs containing both YES1 and thymidylate synthase map to the short arm of chromosome 18, Genomics 15, 442-445 (1993).
    • (1993) Genomics , vol.15 , pp. 442-445
    • Silverman, G.A.1    Kuo, W.-L.2    Taillon-Miller, P.3    Gray, J.W.4
  • 33
    • 0025223330 scopus 로고
    • Expression of cellular-yes protein in mammalian tissues
    • Y.-H. ZHAO, J. G. KRUEGER and M. SUDOL, Expression of cellular-yes protein in mammalian tissues, Oncogene 5, 1629-1635 (1990).
    • (1990) Oncogene , vol.5 , pp. 1629-1635
    • Zhao, Y.-H.1    Krueger, J.G.2    Sudol, M.3
  • 34
    • 0027170840 scopus 로고
    • c-Yes tyrosine kinase activity in human colon carcinoma
    • J. PARK, A. I. MEISLER and C. A. CARTWRIGHT, c-Yes tyrosine kinase activity in human colon carcinoma, Oncogene 8, 2627-2635 (1993).
    • (1993) Oncogene , vol.8 , pp. 2627-2635
    • Park, J.1    Meisler, A.I.2    Cartwright, C.A.3
  • 35
    • 0028981123 scopus 로고
    • Elevated c-yes tyrosine kinase activity in premalignant lesions of the colon
    • S. V. PEÑA, M. F. MELHEM, A. I. MEISLER and C. A. CARTWRIGHT, Elevated c-yes tyrosine kinase activity in premalignant lesions of the colon, Gastroent. 108, 117-124 (1995).
    • (1995) Gastroent. , vol.108 , pp. 117-124
    • Peña, S.V.1    Melhem, M.F.2    Meisler, A.I.3    Cartwright, C.A.4
  • 36
    • 0028816058 scopus 로고
    • Src family of tyrosine kinases: A role of c-yes in colon carcinogenesis?
    • L. A. BOARDMAN and W. E. KARNES JR, Src family of tyrosine kinases: a role of c-yes in colon carcinogenesis? Gastroent. 108, 291-294 (1995).
    • (1995) Gastroent. , vol.108 , pp. 291-294
    • Boardman, L.A.1    Karnes W.E., Jr.2
  • 37
    • 0027300619 scopus 로고
    • The when and how of Src regulation
    • J. A. COOPER and B. HOWELL, The when and how of Src regulation, Cell 73, 1051-1054 (1993).
    • (1993) Cell , vol.73 , pp. 1051-1054
    • Cooper, J.A.1    Howell, B.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.