p-benzoquinone, a reactive metabolite of benzene, prevents the processing of pre-interleukins-1α and -1β to active cytokines by inhibition of the processing enzymes, calpain, and interleukin-1β converting enzyme

Environmental Health Perspectives

Volumn 104, Issue SUPPL. 6, 1996, Pages 1251-1256

  Kalf, George F ^a   Renz, John F ^a   Niculescu, Rodica ^a  

^a THOMAS JEFFERSON UNIVERSITY   (United States)

Author keywords

Benzene; Calpain; Interleukin 1 processing enzyme; p benzoquinone; Pre interleukin 1 processing

Indexed keywords

1,4 BENZOQUINONE; CALPAIN; HYDROQUINONE; INTERLEUKIN 1ALPHA; INTERLEUKIN 1BETA; INTERLEUKIN 1BETA CONVERTING ENZYME;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; BONE MARROW CELL; CONFERENCE PAPER; HEMATOPOIETIC STEM CELL; LONG TERM EXPOSURE; MACROPHAGE; MOUSE; NONHUMAN; PRIORITY JOURNAL;

ANIMALS; BENZENE; BENZOQUINONES; BONE MARROW; BONE MARROW CELLS; CALPAIN; CASPASE 1; CELL LINE; CYSTEINE ENDOPEPTIDASES; ENZYME INHIBITORS; HUMANS; INDOMETHACIN; INTERLEUKIN-1; MICE; PROTEIN PRECURSORS; PROTEIN PROCESSING, POST-TRANSLATIONAL; RECOMBINANT PROTEINS;

EID: 0030457976     PISSN: 00916765     EISSN: None     Source Type: Journal    
DOI: 10.1289/ehp.961041251     Document Type: Article

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