메뉴 건너뛰기




Volumn 35, Issue 9-10, 1996, Pages 1199-1208

Identification of domains in human recombinant GABA(A) receptors that are photoaffinity labelled by [3H]Flunitrazepam and [3H]Ro15-4513

Author keywords

Benzodiazepines; Flunitrazepam; GABA(A) receptor; Hydroxylamine; Ro15 4513

Indexed keywords

4 AMINOBUTYRIC ACID A RECEPTOR; 8 AZIDO 5,6 DIHYDRO 5 METHYL 6 OXO 4H IMIDAZO[1,5 A][1,4]BENZODIAZEPINE 3 CARBOXYLIC ACID ETHYL ESTER; BENZODIAZEPINE RECEPTOR INVERSE STIMULATING AGENT; BENZODIAZEPINE RECEPTOR STIMULATING AGENT; DIAZEPAM; DODECYL SULFATE SODIUM; FLUNITRAZEPAM; HYDROXYLAMINE; RADIOLIGAND; RECEPTOR SUBTYPE; RECEPTOR SUBUNIT; RECOMBINANT RECEPTOR;

EID: 0030457799     PISSN: 00283908     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0028-3908(96)00085-8     Document Type: Article
Times cited : (19)

References (43)
  • 1
    • 0026655484 scopus 로고
    • Receptor classes and the transmittergated ion channels
    • Barnard E.A. Receptor classes and the transmittergated ion channels. Trends Biochem. Sci. 17:1992;368-374.
    • (1992) Trends Biochem. Sci. , vol.17 , pp. 368-374
    • Barnard, E.A.1
  • 3
    • 0017637022 scopus 로고
    • Cleavage at Asn-Gly bonds with hydroxylamine
    • Bornstein P., Balian G. Cleavage at Asn-Gly bonds with hydroxylamine. Meth. Enzym. 47:1977;132-145.
    • (1977) Meth. Enzym. , vol.47 , pp. 132-145
    • Bornstein, P.1    Balian, G.2
  • 4
    • 0022512697 scopus 로고
    • Transmembrane topology and subcellular distribution of the benzodiazepine receptor
    • Czajkowski C., Farb D.H. Transmembrane topology and subcellular distribution of the benzodiazepine receptor. J. Neurosci. 6:1986;2857-2863.
    • (1986) J. Neurosci. , vol.6 , pp. 2857-2863
    • Czajkowski, C.1    Farb, D.H.2
  • 8
    • 0028178754 scopus 로고
    • A receptors: Ligand binding and chloride transporting properties
    • A receptors: ligand binding and chloride transporting properties. Biochemistry. 33:1994;755-763.
    • (1994) Biochemistry , vol.33 , pp. 755-763
    • Dunn, S.M.J.1    Thuynsma, R.P.2
  • 9
    • 0028171397 scopus 로고
    • Molecular pharmacology of γ-aminobutyric acid type A receptor agonists and partial agonist in oocytes injected with different α, β, and γ receptor subunit combinations
    • Eber B., Wafford K.A., Whiting P.J., Krogsgaard-Larsen P., Kemp P.J. Molecular pharmacology of γ-aminobutyric acid type A receptor agonists and partial agonist in oocytes injected with different α, β, and γ receptor subunit combinations. Molec. Pharmac. 46:1994;957-963.
    • (1994) Molec. Pharmac. , vol.46 , pp. 957-963
    • Eber, B.1    Wafford, K.A.2    Whiting, P.J.3    Krogsgaard-Larsen, P.4    Kemp, P.J.5
  • 16
    • 0014949207 scopus 로고
    • Cleavage of structural proteins during the assembly of the head of bacteriophage T4
    • Laemmli U.K. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature. 227:1970;680-685.
    • (1970) Nature , vol.227 , pp. 680-685
    • Laemmli, U.K.1
  • 19
    • 0024421415 scopus 로고
    • GABA receptors: Are cellular differences reflected in function?
    • Matsumoto R.R. GABA receptors: are cellular differences reflected in function? Brain Res. Rev. 14:1989;203-225.
    • (1989) Brain Res. Rev. , vol.14 , pp. 203-225
    • Matsumoto, R.R.1
  • 20
    • 0028575806 scopus 로고
    • A single amino acid of the human γ-aminobutyric acid type A receptor γ2 subunit determines benzodiazepine efficacy
    • Mihic S.J., Whiting P.J., Klein R.L., Wafford K.A., Harris R.A. A single amino acid of the human γ-aminobutyric acid type A receptor γ2 subunit determines benzodiazepine efficacy. J. Biol. Chem. 269:1994;32768-32773.
    • (1994) J. Biol. Chem. , vol.269 , pp. 32768-32773
    • Mihic, S.J.1    Whiting, P.J.2    Klein, R.L.3    Wafford, K.A.4    Harris, R.A.5
  • 21
    • 0021281557 scopus 로고
    • Photoaffinity labeling of benzodiazepine receptors with a partial inverse agonist
    • Mohler H., Sieghart W., Richards J.G., Hunkeler W. Photoaffinity labeling of benzodiazepine receptors with a partial inverse agonist. Eur. J. Pharmac. 102:1984;191-192.
    • (1984) Eur. J. Pharmac. , vol.102 , pp. 191-192
    • Mohler, H.1    Sieghart, W.2    Richards, J.G.3    Hunkeler, W.4
  • 24
    • 0028982279 scopus 로고
    • A receptors of adult rat cerebellum demonstrates two α subunits per receptor oligomer
    • A receptors of adult rat cerebellum demonstrates two α subunits per receptor oligomer. J. Biol. Chem. 270:1995;21285-21290.
    • (1995) J. Biol. Chem. , vol.270 , pp. 21285-21290
    • Pollard, S.1    Thompson, C.L.2    Stephenson, F.A.3
  • 25
    • 0024423323 scopus 로고
    • A benzodiazepine receptors produced in transfected cells
    • A benzodiazepine receptors produced in transfected cells. Science. 245:1989;1389-1392.
    • (1989) Science , vol.245 , pp. 1389-1392
    • Pritchett, D.B.1    Luddens, H.2    Seeburg, P.H.3
  • 26
    • 0026100433 scopus 로고
    • γ-Aminobutyric acid type A receptor point mutation increases the affinity of compounds for the benzodiazepine site
    • Pritchett D.B., Seeburg P.H. γ-Aminobutyric acid type A receptor point mutation increases the affinity of compounds for the benzodiazepine site. Proc. Natn. Acad. Sci. U.S.A. 88:1991;1421-1425.
    • (1991) Proc. Natn. Acad. Sci. U.S.A. , vol.88 , pp. 1421-1425
    • Pritchett, D.B.1    Seeburg, P.H.2
  • 28
    • 0028174520 scopus 로고
    • γ-Aminobutyric acid type A receptors in the rat brain can contain both γ2 and γ3 subunits, but γ1 does not exist in combination with another γ subunit
    • Quirk K., Gillard N.P., Ragan C.I., Whiting P.J., McKernan R.M. γ-Aminobutyric acid type A receptors in the rat brain can contain both γ2 and γ3 subunits, but γ1 does not exist in combination with another γ subunit. Molec. Pharmac. 45:1991;1061-1070.
    • (1991) Molec. Pharmac. , vol.45 , pp. 1061-1070
    • Quirk, K.1    Gillard, N.P.2    Ragan, C.I.3    Whiting, P.J.4    McKernan, R.M.5
  • 29
    • 0028243253 scopus 로고
    • Model of subunit composition of γ-aminobutyric acid A receptor subtypes expressed in rat cerebellum with respect to their α and γ/δ subunits
    • Quirk K., Gillard N.P., Ragan C.I., Whiting P.J., McKernan R.M. Model of subunit composition of γ-aminobutyric acid A receptor subtypes expressed in rat cerebellum with respect to their α and γ/δ subunits. J. Biol. Chem. 269:1991;16020-16028.
    • (1991) J. Biol. Chem. , vol.269 , pp. 16020-16028
    • Quirk, K.1    Gillard, N.P.2    Ragan, C.I.3    Whiting, P.J.4    McKernan, R.M.5
  • 30
    • 0024578737 scopus 로고
    • Photolabeled tryptic degradation products of benzodiazepine-binding proteins are glycopeptides
    • Schmitz E., Reichelt R., Mohler H., Hebebrand J. Photolabeled tryptic degradation products of benzodiazepine-binding proteins are glycopeptides. Fedn Eur. Biochem. Socs Lett. 244:1989;433-438.
    • (1989) Fedn Eur. Biochem. Socs Lett. , vol.244 , pp. 433-438
    • Schmitz, E.1    Reichelt, R.2    Mohler, H.3    Hebebrand, J.4
  • 31
    • 0023932507 scopus 로고
    • Comparison of two different benzodiazepine binding proteins by peptide mapping after limited proteolysis
    • Sieghart W. Comparison of two different benzodiazepine binding proteins by peptide mapping after limited proteolysis. Brain Res. 450:1988;387-391.
    • (1988) Brain Res. , vol.450 , pp. 387-391
    • Sieghart, W.1
  • 32
    • 0020645684 scopus 로고
    • 3H]flunitrazepam to different proteins in various brain regions
    • 3H]flunitrazepam to different proteins in various brain regions. J. Neurochem. 41:1983;47-55.
    • (1983) J. Neurochem. , vol.41 , pp. 47-55
    • Sieghart, W.1    Drexler, G.2
  • 35
    • 0019313418 scopus 로고
    • Molecular heterogeneity of benzodiazepine receptors
    • Sieghart W., Karobath M. Molecular heterogeneity of benzodiazepine receptors. Nature. 286:1980;285-287.
    • (1980) Nature , vol.286 , pp. 285-287
    • Sieghart, W.1    Karobath, M.2
  • 37
    • 0024438843 scopus 로고
    • Mapping the benzodiazepine photoaffinity labelling site with sequence-specific γ-aminobutyric acid A receptor antibodies
    • Stephenson F.A., Duggan M.J. Mapping the benzodiazepine photoaffinity labelling site with sequence-specific γ-aminobutyric acid A receptor antibodies. Biochem. J. 264:1989;199-206.
    • (1989) Biochem. J. , vol.264 , pp. 199-206
    • Stephenson, F.A.1    Duggan, M.J.2
  • 42
    • 0028972886 scopus 로고
    • A receptor α4 subunit: Identification of a unique diazepam-insensitive binding site
    • A receptor α4 subunit: identification of a unique diazepam-insensitive binding site. Eur. J. Pharmac. 291:1995;319-325.
    • (1995) Eur. J. Pharmac. , vol.291 , pp. 319-325
    • Yang, W.1    Drewe, J.A.2    Lan, N.C.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.