Reduced capacity of cardiac efferent sympathetic neurons to release noradrenaline and modify cardiac function in tachycardia-induced canine heart failure

Canadian Journal of Physiology and Pharmacology

Volumn 74, Issue 9, 1996, Pages 1070-1078

  Cardinal, R ^a   Nadeau, R ^b   Laurent, C ^b   Boudreau, G ^b   Armour, J A ^b  

^a HÔPITAL DU SACRÉ COEUR DE MONTRÉAL   (Canada)

^b NONE

Author keywords

Autonomic nervous system; Desensitization; Heart failure

Indexed keywords

ADRENALIN; CATECHOLAMINE; NORADRENALIN;

ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DOG; ELECTROSTIMULATION; FEMALE; HEART FAILURE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MALE; NEUROMUSCULAR SYNAPSE; NONHUMAN; NORADRENALIN RELEASE; PRIORITY JOURNAL; STELLATE GANGLION;

EID: 0030457639     PISSN: 00084212     EISSN: None     Source Type: Journal    
DOI: 10.1139/y96-112     Document Type: Article

References (23)

1. Armour, J.A., and Randall, W.C. 1971. Canine left ventricular intramyocardial pressure. Am. J. Physiol. 220: 1833-1839.
2. Armstrong, P.W., Stopps, T.P., Ford, S.E., and de Bold, A.J. 1986. Rapid ventricular pacing in the dog: pathophysiologic studies of heart failure. Circulation, 74: 1075-1084.
3. Braunwald, E. 1992. Pathophysiology of heart failure. In Heart disease. A textbook of cardiovascular medicine. Edited by E. Braunwald. Saunders, Boston, Mass. pp. 393-418.
4. Burwash, I.G., Morgan, D.E., Koilpilla, C.J., Blackmore, G.L., Johnstone, D.E., and Armour, J.A. 1993. Sympathetic stimulation alters left ventricular function and chamber size. Am. J. Physiol. 264: R1-R7.
5. Butler, C., Watson-Wright, W.M., Wilkinson, M., Johnstone, D.E., and Armour, J.A. 1988. Cardiac effects produced by long-term stimulation of thoracic autonomie ganglia or nerves: implications for interneuronal interactions within the thoracic autonomie nervous system. Can. J. Physiol. Pharmacol. 66: 175-184.
6. Calderone, A., Bouvier, M., Li, K., Juneau, C., de Champlain, J., and Rouleau, J.L. 1991. Dysfunction of the beta- and alpha-adrenergic systems in a model of congestive heart failure. Circ. Res. 69: 332-343.
7. Chidsey, C.A., Kaiser, G.A., Sonnenblick, E.H., Spann, J.F., and Braunwald, E. 1964. Cardiac norepinephrine stores in experimental heart failure in the dog. J. Clin. Invest. 43: 2386-2393.
8. Covell, J.W., Chidsey, C.A., and Braunwald, E. 1966. Reduction of the cardiac response to postganglionic sympathetic nerve stimulation in experimental heart failure. Circ. Res. 19: 51-56.
9. Daly, P.A., and Sole, M.J. 1990. Myocardial catecholamines and the pathophysiology of heart failure. Circulation, 82(Suppl. I): I-35-I-43.
10. Delehanty, J.M., Himura, Y., Elam, H., Hood, W.B., and Liang, C.S. 1994. β-Adrenoceptor downregulation in pacing-induced heart failure is associated with increased interstitial NE content. Am. J. Physiol. 266: H930-H935.
11. Ferguson, D., and Mark, A.L. 1994. Clinical neurocardiology: role of the autonomie nervous system in clinical heart failure. In Neurocardiology. Edited by J.A. Armour and J.L. Ardell. Oxford University Press, New York. pp. 343-363.
12. Gauthier, P., Nadeau, R., and de Champlain, J. 1972. Acute and chronic cardiovascular effects of 6-hydroxydopamine in dogs. Circ. Res. 31:207-219.
13. Himura, Y., Felten, S.Y., Kashiki, M., Lewandowski, T.J., Delehanty, J.M., and Liang, C.S. 1993. Cardiac noradrenergic terminal abnormalities in dogs with experimental congestive heart failure. Circulation, 88: 1299-1309.
14. Juneau, C., Calderone, A., and Rouleau, J.L. 1992. Myocardial β-adrenergic and mechanical properties in pacing-induced heart failure in dogs. Am. J. Physiol. 262: H1458-H1467.
15. Marzo, K.P., Frey, M.T., Wilson, J.R., Liang, B.J., Manning, D.R., Lanoce, V., and Molinoff, P.B. 1991. β-Adrenergic receptor - G protein - adenylate cyclase complex in experimental canine congestive heart failure produced by rapid ventricular pacing. Circ. Res. 69: 1546-1556.
16. Nadeau, R., Lamontagne, D., Cardinal, R., and Armour, J.A. 1988. Coronary sinus norepinephrine concentrations during ventricular tachycardia induced by left stellate ganglion stimulation in dogs. Can. J. Physiol. Pharmacol. 66: 419-421.
17. Péronnet, F., Nadeau, R., Boudreau, G., Cardinal, R., Lamontagne, D., Yamaguchi, N., and de Champlain, J. 1988. Epinephrine release from the heart during left stellate ganglion stimulation in dogs. Am. J. Physiol. 254: R659-R662.
18. Randall, W.C. 1977. Sympathetic control of the heart. In Neural regulation of the heart. Edited by W.C. Randall. Oxford University Press, New York. pp. 45-94.
19. Rose, C.P., Burgess, J.H., and Cousineau, D. 1983. Reduced aortocoronary sinus extraction of epinephrine in patients with left ventricular failure secondary to long-term pressure or volume overload. Circulation, 68: 241-244.
20. Sokal, R.R., and Rohlf, F.J. 1981. Biometry. 2nd ed. W.H. Freeman and Company, New York. pp. 98-127.
21. Watson-Wright, W.M., Wilkinson, M., Johnstone, D.E., Cardinal, R., and Armour, J.A. 1992. Prolonged supramaximal stimulation of canine efferent sympathetic neurons induced desensitization of inotropic responses without a change in myocardial beta-adrenergic receptors. Can. J. Cardiol. 8: 177-186.
22. Watson-Wright, W.M., Wilkinson, M., Cardinal, R., Boudreau, G., and Armour, J.A. 1994. Minimal modification of canine ventricular myocyte cell surface β-adrenoceptors despite desensitisation of ventricular function during exogenous β-adrenoceptor challenge. Cardiovasc. Res. 28: 680-683.
23. Yamaguchi, N., de Champlain, J., and Nadeau, R.A. 1975. Correlation between the response of the heart to sympathetic stimulation and the release of endogenous catecholamines into the coronary sinus of the dog. Circ. Res. 36: 662-668.