Cerebral hypoxia-ischemia increases microsomal iron in newborn piglets

Metabolic Brain Disease

Volumn 11, Issue 4, 1996, Pages 359-367

  Adcock, Lisa M ^a   Yamashita, Yushiro ^a   Goddard Finegold, Jan ^a   Smith, Charles V ^a  

^a BAYLOR COLLEGE OF MEDICINE   (United States)

Author keywords

Cerebral hypoxia ischemia; iron; newborn; oxidant injury

Indexed keywords

CARBONYL DERIVATIVE; IRON;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN HYPOXIA; BRAIN ISCHEMIA; BRAIN MICROSOME; CELL FRACTIONATION; CONTROLLED STUDY; IRON METABOLISM; NEWBORN; NONHUMAN; REPERFUSION; SWINE;

ANIMALS; ANIMALS, NEWBORN; ANOXIA; BRAIN ISCHEMIA; IRON; MICROSOMES; SWINE;

ANIMALIA; SUS SCROFA;

EID: 0030456943     PISSN: 08857490     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF02029496     Document Type: Article

References (28)

1. Armstrong, D.L., Sauls, C.D., and Goddard-Finegold, J. (1987). Neuropathologic findings in short-term survivors of intraventricular hemorrhage. Am. J. Dis. Child. 141:617-621.
2. Artiss, J.D., Vingradov, S., and Zak, B. (1981). Spectrophotometric study of several sensitive reagents for serum iron. Clin. Biochem. 14:311-315.
3. Aruoma, O.I., Halliwell, B., Gajewski, E., and Dizdaroglu, M. (1989). Damage to the bases in DNA induced by hydrogen peroxide and ferric ion chelates. J. Biol. Chem. 264:20509-20512.
4. Ayene, I.S., Dodia, C., and Fisher, A.B. (1992). Role of oxygen in oxidation of lipid and protein during ischemia/reperfusion in isolated perfused rat lung. Arch. Biochem. Biophys. 296:183-189.
5. Babbs, C.F. (1985). Role of iron ions in the genesis of reperfusion injury following successful cardiopulmonary resuscitation: preliminary data and a biochemical hypothesis. Ann. Emerg. Med. 14:777-783.
6. Bradford, M.M. (1976). A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye bonding. Analyt. Bioch. 72:248-254.
7. Corbet, R.J.T., Laptook, A.R., and Olivares, E. (1991). Simultaneous measurement of cerebral blood flow and energy metabolites in piglets using deuterium and phosphorus nuclear magnetic resonance. J. Cereb. Blood Flow Metab. 11:55-65.
8. Floyd, R.A., and Carney, J.M. (1992). Free radical damage to protein and DNA: mechanisms involved and relevant observations on brain undergoing oxidative stress. Ann. Neurol. 32:S22-S27.
9. Gluckman, P.D., and Williams, C.E. (1992). When and why do brain cells die? Dev. Med. Child. Neurol. 34:1010-1021.
10. Goddard-Finegold, J., and Michael, L.H. (1984). Cerebral blood flow and experimental intraventricular hemorrhage. Pediatr. Res. 18:7-11.
11. Halliwell, B. (1987). Oxidants and human disease: some new concepts. FASEB 1:358-364.
12. Harada, J., Takaku, A., Endo, S., Kuwayama, N., and Fukuda, O. (1991). Differences in critical cerebral blood flow with age in swine. J. Neurosurg. 75:103-107.
13. Krause, G.S., Joyce, K.M., Nayini, N.R., Zonia, C.L., Garritano, A.M., Hoehner, T.J., Evans, A.T., Indreri, R.J., Huang, R.R., Aust, S.D., and White, B.C. (1985). Cardiac arrest and resuscitation: brain iron delocalization during reperfusion. Ann. Em. Med. 14:1037-1043.
14. Krause, G.S., Nayini, N.R., White, B.C., Hoehner, T.J., Garritano, A.M., O'Neil, B.J., and Aust, S.D. (1987). Natural course of iron delocalization and lipid peroxidation during the first eight hours following a 15-minute cardiac arrest in dogs. Ann. Em. Med. 16:1200-1205.
15. Laemmli, U.K. (1970). Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227:680-685.
16. Levine, R.L., Williams, J.A., Stadtman, E.R., and Shacter, E. (1994). Carbonyl assays for determination of oxidatively modified proteins. In (Packer L. ed.) Oxygen Radicals in Biological Systems. Academic Press, New York, pp. 346-357.
17. 2+ concentration in isolated rat liver nuclei. Proc. Natl. Acad. Sci. USA 86:453-457.
18. Palmer, C., and Vannucci, R.C. (1993). Potential new therapies for perinatal cerebral hypoxia-ischemia. In (Shankaran S. ed.) Clinics in Perinatology. W.B. Saunders Co., Philadelphia, pp. 411-432.
19. Peliowski, A., and Finer, N.N. (1992). Birth asphyxia in the term infant. In (Sinclair, J.C., and Bracken, M.B., eds.) Effective Care of the Newborn Infant. Oxford University Press, New York, pp. 249-279.
20. Towbin, H., Staehelin, T., and Gordon, J. (1979). Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications. Proc. Natl. Acad. Sci. (USA) 76:4350-4354.
21. Traystman, R.J., Kirsch, J.R., and Koehler, R.C. (1991). Oxygen radical mechanisms of brain injury following ischemia and reperfusion. J. Appl. Physiol. 71:1185-1195.
22. Vannucci, R.C. (1990). Experimental biology of cerebral hypoxia-ischemia: relation to perinatal brain damage. Pediatr. Res. 27:317-326.
23. Volpe, J.J. (1995a). Hypoxic-ischemic encephalopathy: neuropathology and pathogenesis. In Neurology of the Newborn 3rd edition, W.B. Saunders Co., Philadelphia, pp. 279-313.
24. Volpe, J.J. (1995b). Intracranial hemorrhage: germinal matrix-intraventricular hemorrhage of the premature infant. In Neurology of the Newborn 3rd edition, W.B. Saunders Co., Philadelphia, pp. 401-463.
25. Volpe, J.J. (1995c). Hypoxic-ischemic encephalopathy: biochemical and physiological aspects. In Neurology of the Newborn 3rd edition. W.B. Saunders Co., Philadelphia, pp. 211-259.
26. Weis, M., Morgenstern, R., Cotgreave, I.A., Nelson, S.D., and Moldeus, P. (1992). N-acetyl-p-benzoquinone imine-induced protein thiol modification in isolated rat hepatocytes. Biochem. Pharmocol. 43:1493-1505.
27. Williams, C.E., Mallard, C., Tan, W., and Gluckman, P.D. (1993). Pathophysiology of perinatal asphyxia. In (Shankaran S. ed.) Clinics in Perinatology. W.B. Saunders Co., Philadelphia, pp. 305-325.
28. Yamashita., Y., Goddard-Finegold, J., Contant, C.F., Martin, C.G., and Michael, L.H. (1993). Phenobarbital and cerebral blood flow during hypotension in newborn pigs. Pediatr. Res. 33:598-602.