Incidence of childhood leukaemia and non-Hodgkin's lymphoma in the vicinity of nuclear sites in Scotland, 1968-93

Occupational and Environmental Medicine

Volumn 53, Issue 12, 1996, Pages 823-831

  Sharp, L ^a   Black, R J ^b,c   Harkness, E F ^c   McKinney, P A ^c,d  

^a UNIVERSITY OF ABERDEEN   (United Kingdom)

^b INTERNATIONAL AGENCY FOR RESEARCH ON CANCER   (France)

^c HEALTHCARE IMPROVEMENT SCOTLAND   (United Kingdom)

^d Molecular Epidemiology Unit   (United Kingdom)

Author keywords

childhood; leukaemia; nuclear sites

Indexed keywords

ARTICLE; CHILD; CHILDHOOD LEUKEMIA; HUMAN; MAJOR CLINICAL STUDY; NONHODGKIN LYMPHOMA; NUCLEAR INDUSTRY; NUCLEAR REACTOR; PRIORITY JOURNAL; RISK ASSESSMENT; UNITED KINGDOM;

EID: 0030456066     PISSN: 13510711     EISSN: None     Source Type: Journal    
DOI: 10.1136/oem.53.12.823     Document Type: Article

References (35)

1. Heasman MA, Urquhart JD, Kemp IW, Black RJ. Childhood leukaemia in Northern Scotland [letter]. Lancet 1986;i:266 and 355.
2. Committee on Medical Aspects of Radiation in the Environment (COMARE). Second report. Investigation of the possible increased incidence of leukaemia in young people near the Dounreay Nuclear Establishment. Caithness, Scotland. Chairman Professor M Bobrow. London: HMSO, 1988.
3. Black D. Investigation of the possible increased incidence of cancer in West Cumbria. Report of the Independent Advisory Group. London:HMSO,1984.
4. Urquhart JD, Black RJ, Muirhead MJ, Sharp L, Maxwell M, Adams Jones D. Case control study of leukaemia and non-Hodgkin's lymphoma in children in Caithness near the Dounreay nuclear installation. BMJ 1991;302: 687-92.
5. Black RJ, Urquhart JD, Kendrick SW, Bunch KJ, Warner J, Adams Jones D. Incidence of leukaemia and other cancers in birth and school cohorts in the Dounreay area. BMJ 1992;304:1401-5.
6. Black RJ, Sharp L, Harkness EF, McKinney PA. Leukaemia and non-Hodgkin's lymphoma: incidence in children and young adults resident in the Dounreay area of Caithness, Scotland in 1968 91. J Epidemiol Community Health 1994;48:232-6.
7. Heasman MA, Urquhart JD, Black RJ, Kemp IW. Leukaemia in young persons in Scotland: a study of its geographical distribution and relationship to nuclear installations. Health Bull (Edinb) 1987;43:147-51.
8. Roman E, Beral V, Carpenter L, Watson A, Barton C, Ryder H, Aston DL. Childhood leukaemia in the West Berkshire and Basingstoke and Northern Hampshire District Health Authority in relation to nuclear establishments in the vicinity. BMJ 1987;294:597-602.
9. Cook-Mozaffari PJ, Ashwood FL, Vincent T, Forman D, Alderson M. Cancer incidence and mortality in the vicinity of nuclear installations, England and Wales 1959-80. London: HMSO, 1987. (Studies on medical and population subjects. No 51.)
10. Ewings PD, Bowie C. Leukaemia incidence in Somerset with particular reference to Hinkley Point. Somerset Health Authority, 1988.
11. Committee on Medical Aspects of Radiation in the Environment (COMARE) Third Report. Report on the incidence of childhood cancer in the West Berkshire and North Hampshire area, in which are situated the Atomic Weapons Research Establishment, Aldermaston and the Royal Ordnance Factory, Burghfield. Chairman Professor M Bobrow. London: HMSO, 1989.
12. Bithell JF, Dutton SJ, Draper GJ, Neary NM. Distribution of childhood leukaemias and non-Hodgkin's lymphomas near nuclear installations in England and Wales. BMJ 1994;309:501-5.
13. Gardner MJ. Review of reported increases of childhood cancer rates in the vicinity of nuclear installations in the UK. Journal of the Royal Statistical Society Series A 1989;152:307-25.
14. Hills M, Alexander FE Statistical methods used in assessing the risk of disease near a source of possible environmental pollution: a review. Journal of the Royal Statistical Society Series A 1989;152:353-63.
15. Wakeford R, Binks K, Wilkie D. Childhood leukaemia and nuclear installations. Journal of the Royal Statistical Society Series A 1989,152:61-86.
16. Stone RA. Investigation of excess environmental risks around a putative source: statistical problems and a proposed test. Stat Med 1988;7:649-60.
17. Bithell JF, Stone RA. On statistical methods for analysing the geographical distribution of cancer cases near nuclear installations. J Epidemiol Community Health 1989;43: 79-85.
18. Bithell JF. Statistical methods for analysing point-source exposures. In: Elliott P, et al, ed. Geographical and environmental epidemiology: methods for small area studies. Oxford: Oxford University Press, 1992.
19. Glass S, Gray M, Eden OB, Hann IM, Gibson B. Scottish validation study of cancer registration data: childhood leukaemia 1968 81. Leuk Res 1987;2:881-5.
20. McKinney PA, Smith K, Findlay E. The Scottish case control study of childhood leukaemia and cancer: methodology and environmental measures of exposure. Health Bull 1995;53:222-9.
21. Registrar General, Scotland. Annual report. Edinburgh: HMSO, 1992.
22. Carstairs V, Al orris R. Deprivation and health in Scotland. Aberdeen: Aberdeen University Press, 1991.
23. Urquhart J, The investigation of leukaemia incidence around sites of special interest. Nuclear Energy 1991;30: 21-6.
24. Bithell J. The choice of test for detecting raised disease risk near a point source. Stat Med 1995;14:2309-22.
25. McKinney PA, Ironside JW, Harkness EF, Arango JC, Doyle D, Black RJ. Registration quality and descriptive epidemiology of childhood brain tumours in Scotland, 1975-90. Br J Cancer 1994;70:973-9.
26. Breslow NE, Day NE. Statistical methods in cancer research. Vol II. The design and analysis of cohort studies. Lyon: International Agency for Research on Cancer, 1987.
27. Draper GJ, Stiller CA, Cartwright RA, Craft AW, Vincent TJ. Cancer in Cumbria and in the vicinity of the Sellafield nuclear installation, 1963-90. BMJ 1993;306: 89-94.
28. Draper GJ, Vincent TJ, O'Connor CM, Stiller CA. Socioeconomic factors and variations in incidence rates between country districts. In: Draper GJ, ed. The geographical epidemiology of childhood leukaemia and non-Hodgkin lymphomas in Great Britain, 1966-83. London: HMSO, 1991. (Studies on Medical and Population Subjects. No 53.)
29. Alexander FE, McKinney PA, Ricketts TJ, Cartwright RA. Community lifestyle characteristics and risk of acute lym-phoblastic leukaemia in children. Lancet 1990;336: 1461-6.
30. Greaves MF, Alexander FE. An infectious aetiology for common acute lymphoblastic leukaemia in childhood. Leukaemia 1993;7:349-60.
31. Kinlen LJ, O'Brien F, Clark K, Balkwill A, Matthews F. Rural population mixing and childhood leukaemia: effects of the North Sea oil industry in Scotland, including the area near Dounreay nuclear site. BMJ 1993;306:743-8.
32. Jablon S, Hrubec Z, Boice JD junior. Cancer in populations living near nuclear facilities: a survey of mortality nationwide and incidence in two states. JAMA 1991; 265:1403-8.
33. Michaelis J, Keller B, Haaf G, Kaatsch P. Incidence of childhood malignancies in the vicinity of West German nuclear power plants. Cancer Causes Control 1992;3: 255-63.
34. Hill C, Laplanche A. Overall mortality and cancer mortality around French nuclear sites. Nature 1990;347:755-7.
35. McLaughlin JR, Clarke AE, Nishri ED, Anderson TW. Childhood leukaemia in the vicinity of Canadian nuclear facilities. Cancer Causes Control 1993;4:51-8.