Karyotypic characteristics of borderline malignant tumors of the ovary: Trisomy 12, trisomy 7, and r(1) as nonrandom features

Cancer Genetics and Cytogenetics

Volumn 92, Issue 2, 1996, Pages 95-98

  Pejovic, Tanja ^a   Iosif, Constantin S ^a   Mitelman, Felix ^a   Heim, Sverre ^a,b  

^a LUND UNIVERSITY HOSPITAL   (Sweden)

^b OSLO UNIVERSITY HOSPITAL   (Norway)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; CANCER STAGING; CHROMOSOME 1; CHROMOSOME 12; CHROMOSOME 7; CHROMOSOME BANDING PATTERN; CLINICAL ARTICLE; CYTOGENETICS; FEMALE; HISTOLOGY; HUMAN; HUMAN CELL; HUMAN TISSUE; KARYOTYPE; OVARY TUMOR; PHENOTYPE; PRIORITY JOURNAL; TRISOMY;

ADENOCARCINOMA, MUCINOUS; CARCINOMA, PAPILLARY; CHROMOSOME MAPPING; CHROMOSOMES, HUMAN, PAIR 1; CHROMOSOMES, HUMAN, PAIR 12; CHROMOSOMES, HUMAN, PAIR 7; CYSTADENOMA, SEROUS; FEMALE; HUMANS; KARYOTYPING; NEOPLASM STAGING; OVARIAN NEOPLASMS; TRISOMY;

EID: 0030455751     PISSN: 01654608     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0165-4608(96)00169-0     Document Type: Article

References (27)

1. 1. Czernobilsky B (1987): Common epithelial tumors of the ovary. In: Kurman RJ (ed). Blaustein's Pathology of the Female Genital Tract. Springer-Verlag, New York, Berlin Heidelberg, pp. 560-606.
2. 2. Taylor HC Jr (1959): Studies in the clinical and biological evolution of adenocarcinoma of the ovary. J Obstetr Gynecol Br Commonwealth 66:827-842.
3. 3. Pejovic T, Heim S, Mandahl N, Elmfors B, Floderus U-M, Furgyik S, Helm G, Willen H, Mitelman F (1989): Consistent occurrence of a 19p+ marker chromosome and loss of 11p material in ovarian seropapillary cystadenocarcinomas. Genes Chromosom Cancer 1:167-171.
4. 4. ISCN (1995): An International System for Human Cytogenetic Nomenclature. Mitelman F (ed); S. Karger, Basel, pp. 1-114.
5. 5. Knoerr Gaertner H, Schulmann R, Kraus H, Uebele-Kallhardt B (1977): Comparative cytogenetic and histologic studies on early malignant transformation in mesothelial tumors of the ovary. Human Genet 35:281-297.
6. 6. Crickard K, Marinello MJ, Crickard U, Satchidanad SK, Yoonesi M, Caglar H (1986): Borderline malignant serous tumors of the ovary maintained on extracellular matrix: Evidence for clonal evolution and invasive potential. Cancer Genet Cytogenet 23:135-143.
7. 7. Samuelson J, Leung WY, Schwartz PE, Ny H, Yang-Feng T (1990): Trisomy 12 in various ovarian tumors of benign to low malignancy. Am J Hum Genet 47:suppl A16.
8. 8. Tharapel SA, Qumsiyek MB, Photopulos G (1991): Numerical chromosome abnormalities associated with early clinical stages of gynecologic tumors. Cancer Genet Cytogenet 55:89-96.
9. 9. Yang-Feng T, Li S, Leung WY, Carcangiu ML, Schwartz PE (1991): Trisomy 12 and K-ras-2 amplification in human ovarian tumors. Int J Cancer 48:678-681.
10. 10. Jenkins RB, Barfelt D Jr, Stalboerger P, Persons D, Dahl RJ, Podratz K, Kelhey G, Hartmann L (1993): Cytogenetic studies of epithelial ovarian carcinoma. Cancer Genet Cytogenet 71:76-86.
11. 11. Thompson FH, Liu Y, Emerson J, Weinstein R, Makar R, Trent JM (1994): Simple numerical abnormalities as primary karyotypic changes in ovarian carcinoma. Genes Chromosom Cancer 10:262-266.
12. 12. Pejovic T, Heim S, Mandahl N, Elmfors B, Floderus U-M, Furgyik S, Helm G, Willen H, Mitelman F (1990): Trisomy 12 is a consistent chromosomal aberration in benign ovarian tumors. Genes Chromosom Cancer 2:48-52.
13. 13. Pejovic T, Heim S, Mandahl N. Baldertop B, Elmfors B, Floderus U-M, Furgyik S, Helm G, Himmelmann A, Willen H, Mitelman F (1992): Chromosome aberrations in 35 primary ovarian carcinomas. Genes Chromosom Cancer 4:58-68.
14. 14. Heim S, Mitelman F (1995): Cancer Cytogenetics. Wiley-Liss, New York.
15. 15. Mitelman F (1994): Catalog of Chromosome Aberrations in Cancer. Wiley-Liss, New York.
16. 16. Leung WY, Schwartz PE, Ng HT, Yang-Feng T (1990): Trisomy 12 in benign fibroma and granulosa cell tumor of the ovary. Gynecol Oncol 38:28-31.
17. 17. Mrózek K, Nedoszytko B, Babinski M, Mrózek E, Hrabowska M, Emerich J, Limon J (1990): Trisomy of chromosome 12 in a case of thecoma of the ovary. Gynecol Oncol 36:413-416.
18. 18. Fletcher JA, Gibas Z, Donovan K, Perez-Artayde A, Genest D, Morton CC, Lage LM (1991): Ovarian granulosa-stromal tumors are characterized by trisomy 12. Am J Pathol 138: 515-520.
19. 19. Gibas Z, Prout GR, Pontes JE, Connolly JG, Sandberg AA (1986): A possible specific chromosome change in transitional cell carcinoma of the bladder. Cancer Genet Cytogenet 19:229-238.
20. 20. Pandis N, Heim S, Bardi G, Floderus U-M, Willen H, Mandahl N, Mitelman F (1990): Parallel karyotypic evolution and tumor progression in uterine leiomyoma. Genes Chromosom Cancer 2:311-317.
21. 21. Bardi G, Johansson B, Pandis N, Heim S, Mandahl N, Andren-Sandberg A, Hagerstrand I, Mitelman F (1991): Trisomy 7 in short-term cultures of colorectal adenocarcinomas. Genes Chromosom Cancer 3:149-152.
22. 22. Lee JS, Pathak S, Hopwood V, Tomasevic B, Mullins TD, Bauer FL, Spitzer G, Neidhart J (1987): Involvement of chromosome 7 in primary lung tumor and non-malignant normal tissue. Cancer Res 47:6349-6352.
23. 23. Pejovic T, Heim S, Orndal C, Jin Y, Mandahl N, Willen H, Mitelman F (1990): Simple numerical chromosome aberrations in well differentiated malignant epithelial tumors. Cancer Genet Cytogenet 49:95-101.
24. 24. Johansson B, Heim S, Mandahl N, Mertens F, Mitelman F (1993): Trisomy 7 in non-neoplastic cells. Genes Chromosom Cancer 6:199-205.
25. 25. Elfing P, Aman P, Mandahl N, Lundgren R, Mitelman F (1995): Trisomy 7 in non-neoplastic epithelial kidney cells. Cytogenet Cell Genet 69:90-96.
26. 26. Pandis N, Heim S, Bardi G, Idvall I, Mandahl N, Mitelman F (1993): Chromosome analysis of 20 breast carcinomas: Cytogenetic multiclonality and pathologic correlations. Genes Chromosom Cancer 6:51-57.
27. 27. Orndal C, Mandahl N, Rydholm A, Willen H, Brosjo O, Heim S, Mitelman F (1992): Supernumerary ring chromosomes in five bone and soft tissue tumors of low to borderline malignancy. Cancer Genet Cytogenet 60:170-175.