Octanoate increases cytosolic Ca2+ concentration and membrane conductance in ovine pancreatic acinar cells

Journal of Comparative Physiology B: Biochemical, Systemic, and Environmental Physiology

Volumn 166, Issue 6, 1996, Pages 369-374

  Katoh, K ^a   Ohbo, M ^a   Wakui, M ^b  

^a TOHOKU UNIVERSITY   (Japan)

^b HIROSAKI UNIVERSITY   (Japan)

Author keywords

Acinar cells; Cytosolic calcium; Exocrine pancreas; Short chain fatty acids

Indexed keywords

ACETYLCHOLINE; AMYLASE; ANTIHYPERTENSIVE AGENT; CALCIUM; OCTANOIC ACID; OCTANOIC ACID DERIVATIVE;

ANIMAL; ARTICLE; CELL MEMBRANE; CELL MEMBRANE POTENTIAL; CYTOLOGY; CYTOSOL; DOSE RESPONSE; DRUG EFFECT; ENZYMOLOGY; METABOLISM; PANCREAS ISLET; PATCH CLAMP; SHEEP;

ACETYLCHOLINE; AMYLASES; ANIMALS; ANTIHYPERTENSIVE AGENTS; CALCIUM; CELL MEMBRANE; CYTOSOL; DOSE-RESPONSE RELATIONSHIP, DRUG; ISLETS OF LANGERHANS; MEMBRANE POTENTIALS; OCTANOIC ACIDS; PATCH-CLAMP TECHNIQUES; SHEEP;

EID: 0030454678     PISSN: 01741578     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF02336919     Document Type: Article

References (32)

1. Amsterdam A, Jamieson JD (1972) Structural and functional characterization of isolated pancreatic cells. Proc Natl Acad Sci USA 69: 3082-3032
2. Berrige MJ (1991) Cytoplasmic calcium oscillations: a two pool model. Cell Calcium 12: 63-72
3. Ekokoski E, Forss L, Tornquist K (1994) Inhibitory action of fatty acids on calcium fluxes in thyroid FRTL-5 cells. Mol Cell Endocrinol 103: 125-132
4. + channel by trypsin in guinea-pig ventricular myocytes. J Physiol (Lond) 466: 707-726
5. 2+ indicators with greatly improved fluorescence properties. J Biol Chem 260. 3440-3450
6. Harada E (1985) Comparison of pancreatic digestive enzyme secretion induced by volatile fatty acids in mice, Japanese field voles and goats. Comp Biochem Physiol 81A: 539-543
7. Harada E, Kato S (1983) Effect of short-chain fatty acids on the secretory response of the ovine exocrine pancreas. Am J Physiol 24: G284-G290
8. 2+ gradients triggering unidirectional fluid secretion from exocrine pancreas. Nature 348: 735-738
9. Kato S, Katoh K, Barej W (1991) Regulation of exocrine pancreatic secretion in ruminants. In: Tsuda T et al. (eds) Physiological aspects of digestion and metabolism in ruminants. Academic Press, San Diego, pp 89-109
10. Katoh K (1995) Effects of short-chain fatty acids on exocrine and endocrine pancreatic secretion. In: Cummings JH et al. (eds) Physiological and clinical aspects of short-chain fatty acids. Cambridge University Press, Cambridge, pp 223-231
11. Katoh K, Tsuda T (1984) Effects of short-chain fatty acids on acinar cells of the exocrine pancreas in sheep. J Physiol (Lond) 356: 479-489
12. Katoh K, Tsuda T (1985) Effects of secretagogues on membrane potential and input resistance of pancreatic acinar cells of sheep. Res Vet Sci 38: 250-251
13. Katoh K, Tsuda T (1987) Effects of intravenous injection of butyrate on the exocrine pancreatic secretion in guinea pigs. Comp Biochem Physiol 87A: 569-572
14. Katoh K, Wakui M (1993) Short-chain fatty acids (SCFAs) increase cytosolic calcium concentrations, inward current and amylase release in pancreatic acinar cells. Short Chain Fatty Acids (Falk Symposium No. 73) Abstract No. B14
15. Katoh K, Yajima T (1989) Effects of butyric acid and analogues on amylase release from pancreatic segments of sheep and goats. Pflügers Archiv 413: 256-260
16. Merrit JE, Armstrong WP, Benham CD, Hallam TJ, Jacob R, Jaxa-Chamiec A, Leigh BK, McCarthy SA, Moores KE, Rink TJ (1990) SK&F 96365, a novel inhibitor of receptor-mediated calcium entry. Biochem J 271: 515-522
17. Ohbo M (1991) Stimulatory effects of fatty acids on amylase release from ovine and rodent pancreatic tissues and cells. Masters dissertation, Tohoku University, Sendai, Japan
18. Ohbo M, Katoh K, Sasaki Y (1989) Effects of short-, medium- and long-chain fatty acids on amylase release from pancreatic segments of rats. Asian-Australasian J Anim Sci 2: 193-194
19. Ohbo M, Katoh K, Sasaki Y (1996) Effects of saturated fatty acids on amylase release from exocrine pancreatic segments of sheep, rats, hamsters, field voles and mice. J Comp Physiol (in press)
20. Ordway RW, Singer JJ, Walsh JV (1991) Direct regulation of ion channels by fatty acids. Trend Neurosci 14: 96-100
21. - current recording in single pancreatic acinar cells. EMBO J 9: 697-704
22. Petersen OH (1992) Stimulus-secretion coupling: cytoplasmic calcium signals and the control of ion channels in exocrine acinar cells. J Physiol (Lond) 448: 1-51
23. 2+ signals evoked by activation of receptors linked to inositol lipid hydrolysis: mechanism of generation. J Membr Biol 118: 93-105
24. + channels from pancreatic β-cells isolated from the mouse. J Physiol (Lond) 459: 240P
25. Stevens CE (1988) Comparative physiology of the vertebrate digestive system. Cambridge University Press, Cambridge, pp 159-190
26. Stremmel W, Diede HE (1989) Fatty acid uptake by human cell lines represents a carrier-mediated uptake process. Biochim Biophys Acta 1013: 218-222
27. 2+ pools in rat pancreatic acinar cells. J Membr Biol 109: 173-179
28. Wakui M, Potter BVL, Petersen OH (1989) Pulsatile intracellular calcium release does not depend on fluctuations in inositol trisphosphate concentration. Nature 339: 317-320
29. Warnotte C, Gilon P, Nenquin M, Henquin J-C (1994) Mechanisms of the stimulation of insulin release by saturated fatty acids Diabetes 43. 703-711
30. Watson AJM, Brennan EA, Farthing MJG, Fairclough PD (1991) Acetate uptake by intestinal brush border membrane vesicles. Gut 32: 383-385
31. Wrong OM (1995) Definition and history. In: Cummings JH et al. (eds) Physiological and clinical aspects of short-chain fatty acids. Cambridge University Press, Cambridge, pp 1-14
32. Zar JH (1984) Biostatistical analysis, 2nd edn. Prentice-Hall, Englewood Cliffs