Selective resistance of LDL core lipids to iron-mediated oxidation: Implications for the biological properties of iron-oxidized LDL

Arteriosclerosis, Thrombosis, and Vascular Biology

Volumn 16, Issue 12, 1996, Pages 1580-1587

  Tribble, Diane L ^a   Chu, Berbie M ^a   Levine, Gerri A ^a   Krauss, Ronald M ^a   Gong, Elaine L ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

copper; hemin; iron; lipid peroxidation; parinaric acid

Indexed keywords

COPPER; FERRIC ION; HEMIN; LOW DENSITY LIPOPROTEIN; PARINARIC ACID;

ANIMAL CELL; ARTICLE; LIPID PEROXIDATION; LIPOPROTEIN METABOLISM; MOLECULAR DYNAMICS; MOLECULAR INTERACTION; MOUSE; NONHUMAN; OXIDATION REDUCTION REACTION; PRIORITY JOURNAL; PROTEIN MODIFICATION;

EID: 0030454224     PISSN: 10795642     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.ATV.16.12.1580     Document Type: Article

References (35)

1. Steinberg D, Parthasarathy S, Carew TE, Khoo JC, Witztum JL. Beyond cholesterol. Modifications of low-density lipoprotein cholesterol that increase its atherogenicity. New Engl J Med. 1988;320:915-924.
2. Steinbrecher UP, Witztum JL, Parthasarathy S, Steinberg D. Decrease in active amino groups during oxidation or endothelial cell modification of LDL: correlation with changes in receptor-mediated catabolism. Arteriosclerosis. 1987;7:135-143.
3. Steinbrecher UP. Oxidation of human low density lipoprotein results in derivitization of lysine residues of apolipoprotein B by lipid peroxide decomposition products. J Biol Chem. 1987;262:3603-3608.
4. Quinn MT, Parthasarathy S, Fong LG, Steinberg D. Oxidatively modified lipoproteins: a potential role in the recruitment and retention of monocyte/macrophages during atherogenesis. Proc Natl Aca Sci USA. 1987;84:2995-2998.
5. Quinn MT, Parthasarathy S, Steinberg D. Lysophosphatidylcholine: a chemotactic factor for human monocytes and its potential role in atherogenesis. Proc Natl Aca Sci USA. 1988;85:2805-2809.
6. Hessler JR, Robertson AL Jr, Chisolm GM. LDL cytotoxicity and its inhibition by HDL in human vascular smooth muscle cells in culture. Atherosclerosis. 1979;32,213-229.
7. Henriksen T, Evensen SA, Carlander B. Injury to human endothelial cells in culture induced by low density lipoproteins. Scand J Clin Lab Invest. 1979;39,361-367.
8. Fox PL, Chisolm GM, Di Corleto PE. Lipoprotein-mediated inhibition of endothelial cell production of platelet-derived growth factor-like protein depends on free radical lipid peroxidation. J Biol Chem. 1987;262,6046-6054.
9. Berliner JA, Territo MC, Sevanian A, Ramin S, Kim JA, Bamshad B, Esterson M, Fogelman AM. Minimally modified low density lipoprotein stimulates monocyte endothelial interactions. J Clin Invest. 1990;85,1260-1266.
10. Rajavashisth TB, Andalibi A, Territo MC, Berliner JA, Navab M, Fogelman AM, Lusis AJ. Induction of endothelial cell expression of granulocyte and macrophage colony-stimulating factors by modified low-density lipoproteins. Nature. 1990;344,254-257.
11. Cushing SD, Berliner JA, Valente AJ, Territo MC, Navab M, Parhami F, Gerrity R, Schwartz CJ, Fogelman AM. Minimally modified low density lipoprotein induces monocyte chemotactic protein 1 in human endothelial cells and smooth muscle cells. Proc Natl Aca Sci USA. 1990;87:5134-5138.
12. Drake TA, Hannani K, Fei HH, Lavi S, Berliner JA. Minimally oxidized low-density lipoprotein induces tissue factor expression in cultured human endothelial cells. Am J Pathol. 1991;138:601-607.
13. Chisolm GM, Ma G, Irwin KC, Martin LL, Gunderson KG, Linberg LF, Morel DW, DiCorleto PE. 7β-Hydroperoxycholest-5-en-3β-ol, a component of human atherosclerotic lesions, is the primary cytotoxin of oxidized human low density lipoprotein. Proc Natl Aca Sci USA. 1994;91:11452-11456.
14. Watson AD, Navab M, Hama SY, Sevanian A, Prescott SM, Stafforini DM, McIntyre TM, La Du BN, Fogelman AM, Berliner JA. Effect of platelet-activating factor acetylhydrolase on the formation and action of minimally oxidized low density lipoprotein. J Clin Invest. 1995;95:774-782.
15. Tribble DL, Krauss RM, Lansberg MG, Kuypers FA, van den Berg JJM. Greater oxidative susceptibility of the surface monolayer in small dense LDL may contribute to differences in susceptibility to copper-induced oxidation among LDL density subfractions. J Lipid Res. 1995;36:662-671.
16. Tribble DL, van den Berg JJM, Motchnik P, Ames BN, Lewis D, Chait A, Krauss RM. Oxidative susceptibility of low density lipoprotein subfractions is related to their ubiquinol-10 and α-tocopherol content. Proc Natl Aca Sci USA. 1994;94:1183-1187.
17. Schuster B, Prassl R, Nigon F, Chapman MJ, Laggner P. Core lipid structure is a major determinant of the oxidative resistance of low density lipoprotein. Proc Natl Acad Sci USA. 1995;92:2509-2513.
18. Tribble DL, Chu BM, Gong EL, vanVenrooij F, Nichols A. HDL antioxidant effects as assessed using a nonexchangable probe to monitor particle-specific oxidation kinetics in LDL-HDL mixtures. J Lipid Res. 1995;36:2580-2589.
19. Lindgren FT, Jensen LC, Wills RD, Freeman NK. Flotation rates, molecular weights, and hydrated densities of the low density lipoproteins. Lipids. 1969; 4:337-345.
20. Markwell MAK, Haas SM, Bieber LL, Tolbert NE. A modification of the Lowry procedure to simplify protein determination in membrane and lipoprotein systems. Anal Biochem. 1978; 87:206-210.
21. Kuzuya M, Yamada K, Hayashi T, FUnaki C, Naito M, Asai K, Kuzuya F. Oxidation of low density lipoprotein by copper and iron in phosphate buffer. Biochim Biophys Acta. 1991;1084:198-201.
22. Balla G, Jacob HS, Eaton JW, Belcher JD, Vercellotti GM. Hemin: A possible physiological mediator of low density lipoprotein oxidation and endothelial injury. Arterioscler Thromb. 1991;11:1700-1711.
23. Bisgaier CL, Minto LL, Essenburg AD, White A, Horman R. Use of fluorescent cholesteryl ester microemulsions in cholesteryl ester transfer assays. J Lipid Res. 1993;34:1625-1634.
24. Lynch SM, Frei B. Reduction of copper, but not iron, by human low density lipoprotein (LDL). The implications for metal ion-dependent oxidative modification of LDL. J Biol Chem. 1995;270:5158-5163.
25. Kim RS, LaBella FS. Comparison of analytical methods for monitoring autooxidation profiles of authentic lipids. J Lipid Res. 1987; 28:1110-1117.
26. Krauss RM, Lindgren FT, Wong A, Anderson B, Pan SS, Lewis SB. Measurement of HDL and other lipoproteins by quantitative electrophoresis. In: Lippel K, ed. Report of the HDL Methodology Workshop, NIH Publication No. 79-1661, San Francisco, March, 1979:114-129.
27. Bilheimer DW, Eisenberg S, Levy RI. The metabolism of very low density lipoprotein proteins. I. Preliminary in vitro and in vivo observations. Biochim Biophys Acta. 260:212-221,1972.
28. Lynch SM, Frei B. Mechanisms of copper- and iron-dependent oxidative modification of human low density lipoprotein. J Lipid Res. 1993;34:1745-1753.
29. Geiseg SP, Esterbauer H. Low density lipoprotein is saturable by prooxidant copper. FEBS Lett. 1994;343:188-194.
30. Esterbauer H, Gebicki J, Puhl H, Jurgens G. The role of lipid peroxidation and antioxidants in oxidative modification of LDL. Free Rad Biol Med. 1992;13:341-390.
31. Zawadzki Z, Milne RW, Marcel YL. An immunochemical marker of low density lipoprotein oxidation. J Lipid Res. 1989;30:885-891.
32. Gandjini H, Gambert P, Athias A, Lallemant C. Resistance to LDL oxidative modifications of an N-terminal apolipoprotein B epitope. Atherosclerosis. 1991;89:83-93.
33. Singh RJ, Feix JB, Mchaourab HS, Hogg N, Kalyanaraman B. Spin-labeling study of the oxidative damage to low-density lipoprotein. Arch Biochem Biophys. 1995;320:155-161.
34. Haberland ME, Olch CL, Fogelman AM. Role of lysines in mediating interaction of modified low density lipoproteins with the scavenger receptor of human monocyte macorphages. J Biol Chem. 1984;259: 11305-11311.
35. Haberland ME, Fogelman AM, Edwards PA. Specificity of receptor-mediated recognition of malondialdehyde-modified low density lipoproteins. Proc Natl Aca Sci USA. 1982;79:1712-1716.