Effects of stimulation of phrenic afferents on cervical respiratory interneurones and phrenic motoneurones in cats

Journal of Physiology

Volumn 497, Issue 3, 1996, Pages 803-812

  Iscoe, Steve ^a,b   Duffin, James ^a  

^a UNIVERSITY OF TORONTO   (Canada)

^b QUEEN S UNIVERSITY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL EXPERIMENT; ARTICLE; CAT; CERVICAL SPINE; EXCITATORY POSTSYNAPTIC POTENTIAL; FEMALE; INHIBITORY POSTSYNAPTIC POTENTIAL; INTERNEURON; LATENT PERIOD; MOTONEURON; NERVE CONDUCTION; NERVE POTENTIAL; NONHUMAN; PHRENIC NERVE; PRIORITY JOURNAL; RESPIRATORY NERVE CELL; SENSORY NERVE;

EID: 0030453942     PISSN: 00223751     EISSN: None     Source Type: Journal    
DOI: 10.1113/jphysiol.1996.sp021811     Document Type: Article

References (40)

1. BALKOWIEC, A., KUKULA, K. & SZULCZYK, P. (1995). Functional classification of afferent phrenic nerve fibres and diaphragmatic receptors in cats. Journal of Physiology 483, 759-768.
2. BELLINGHAM, M. C. (1989). Integration of inhibitory inputs to phrenic motoneurones. PhD Thesis, The Australian National University, Canberra, Australia.
3. 5 segment of the spinal cord of the cat. Brain Research 533, 141-146.
4. BIGLAND-RITCHIE, B., JOHANSSON, R., LIPPOLD, O. C. J., SMITH, S. & WOODS, J. J. (1983). Changes in motoneuron firing rates during sustained maximal voluntary contractions. Journal of Physiology 340, 335-346.
5. CLELAND, C. L. & UETTING, P. A. (1993). Respiratory-modulated and phrenic afferent-driven neurons in the cervical spinal cord (04-06) of the fluorocarbon-perfused guinea pig. Experimental Brain Research 93, 307-311.
6. DOUSE, M. A., DUFFIN, J., BROOKS, D. & FEDORKO, L. (1992). Role of upper cervical inspiratory neurons studied by cross-correlation in the cat. Experimental Brain Research 90, 153-162.
7. DUFFIN, J. & ISCOE, S. (1996). The possible role of 05 segment inspiratory interneurons investigated by cross-correlation with phrenic motoneurons in decerebrate cats. Experimental Brain Research (in the Press).
8. DURON, B. & CONDAMIN, M. (1970). Etude an microscope électronique de la composition amyélinique du nerf phrenique du chat. Comptes Rendues des Séances de la Société de la Biologie 164, 577-583.
9. FEDORKO, L. & MERRILL, E. G. (1984). Axonal projections from the rostral expiratory neurones of the Bötzinger complex to medulla and spinal cord in the cat. Journal of Physiology 350, 487-496.
10. GANDEVIA, S. C., MACEFIELD, G., BURKE, D. & MCKENZIE, D. K. (1990). Voluntary activation of human motor axons in the absence of muscle afferent feedback. The control of the deafferented hand. Brain 113, 1563-1581.
11. GARLAND, S. J. (1991). Role of small diameter afferents in reflex inhibition during human muscle fatigue. Journal of Physiology 435, 547-558.
12. GARLAND, S. J., ENOKA, R. M., SERRANO, L. P. & ROBINSON, G. A. (1994). Behavior of motor units in human biceps brachii during a submaximal fatiguing contraction. Journal of Applied Physiology 76, 2411-2419.
13. GILL, P. K. & KUNO, M. (1963). Excitatory and inhibitory actions on phrenic motoneurones. Journal of Physiology 168, 274-289.
14. GILL, P. K. & KUNO, M. (1963). Properties of phrenic motoneurones. Journal of Physiology 168, 258-273.
15. GOSHGARIAN, H. G. & RAFOLS, J. A. (1984). The ultrastructure and synaptic architecture of phrenic motor neurons in the spinal cord of the adult rat. Journal of Neurocytology 13, 85-109.
16. GOSHGARIAN, H. G. & ROUBAL, P. J. (1986). Origin and distribution of phrenic primary afferent nerve fibers in the spinal cord of the adult rat. Experimental Neurology 92, 624-638.
17. GRAHAM, R., JAMMES, Y., DELPIERRE, S., GRIMAUD, C. & Roussos, C. (1986). The effects of ischemia, lactic acid and hypertonic sodium chloride on phrenic afferent discharge during spontaneous diaphragmatic contraction. Neuroscience Letters 67, 257-262.
18. GRIMBY, L., HANNERZ, J. & HEDMAN, B. (1981). The fatigue and voluntary discharge properties of single motor units in man. Journal of Physiology 316, 545-554.
19. HAYWARD, L., WESSELMANN, U. & RYMER, W. Z. (1991). Effects of muscle fatigue on mechanically sensitive afferents of slow conduction velocity in the cat triceps surae. Journal of Neurophysiology 65, 360-370.
20. HILAIRE, G., KHATIB, M. & MONTEAU, R. (1983). Spontaneous respiratory activity of phrenic and intercostal Renshaw cells. Neuroscience Letters 43, 97-101.
21. HUSSAIN, S. N. A., MAGDER, S., CHATILLON, A. & Roussos, C. (1990). Chemical activation of thin-fiber phrenic afferents: Respiratory responses. Journal of Applied Physiology 69, 1002-1011.
22. JAMMES, Y. & BALZAMO, E. (1992). Changes in afferent and efferent phrenic activities with electrically induced diaphragmatic fatigue. Journal of Applied Physiology 73, 894-902.
23. JAMMES, Y., BUCHLER, B., DELPIERRE, S., RASIDAKIS, A., GRIMAUD, C. & ROUSSOS, C. (1986). Phrenic afferents and their role in inspiratory control. Journal of Applied Physiology 60, 854-860.
24. JODKOWSKI, J. S., VIANA, F., DICK, T. E. & BERGER, A. J. (1987). Electrical properties of phrenic motoneurons in the cat: correlation with respiratory drive. Journal of Neurophysiology 58, 105-124.
25. KAUFMAN, M. P. (1995). Afferents from limb skeletal muscle. In Regulation of Breathing, ed. DEMPSEY, J. A. & PACK, A. I., pp. 583-616, Marcel Dekker, New York.
26. LIPSKI, J., FYFFE, R. E. W. & JODKOWSKI, J. (1985). Recurrent inhibition of cat phrenic motoneurons. Journal of Neuroscience 5, 1545-1555.
27. MACRON, J. M. & MARLOT, D. (1986). Effects of stimulation of phrenic afferent fibers on medullary respiratory neurons in cat. Neuroscience Letters 63, 231-236.
28. MACRON, J. M., MARLOT, D. & DURON, B. (1985). Phrenic afferent input to the lateral medullary reticular formation of the cat. Respiration Physiology 59, 155-167.
29. MARLOT, D., MACRON, J.-M. & DURON, B. (1988). Effects of ipsilateral and contralateral cervical phrenic afferents stimulation on phrenic motor unit activity in the cat. Brain Research 450, 373-377.
30. MARSDEN, C. D., MEADOWS, J. C. & MERTON, P. A. (1983). 'Muscular wisdom' that minimizes fatigue during prolonged effort in man: peak rates of motoneuron discharge and slowing of discharge during fatigue. In Motor Control Mechanisms in Health and Disease, ed. DESMEDT, J. E., pp. 169-211. Raven Press Ltd, New York.
31. MERRILL, E. G. & FEDORKO, L. (1984). Monosynaptic inhibition of phrenic motoneurons: a long descending projection from Bötzinger neurons. Journal of Neuroscience 4, 2350-2353.
32. NAKAZONO, Y. & AOKI, M. (1994). Excitatory connections between upper cervical inspiratory neurons and phrenic motoneurons in cats. Journal of Applied Physiology 77, 679-683.
33. REVELETTE, W. R., JEWELL, L. A. & FRAZIER, D. T. (1988). Effect of diaphragm small-fiber afferent stimulation on ventilation in dogs. Journal of Applied Physiology 65, 2097-2106.
34. RUDOMIN, P., QUEVEDO, J. & EGUIBAR, J. R. (1993). Presynaptic modulation of spinal reflexes. Current Opinion in Neurobiology 3, 997-1004.
35. SPECK, D. F. (1989). Bötzinger complex region role in phrenic-tophrenic inhibitory reflex of cat. Journal of Applied Physiology 67, 1364-1370.
36. SPECK, D. F. & REVELEITE, W. R. (1987a). Attenuation of phrenic motor discharge by phrenic nerve afferents. Journal of Applied Physiology 62, 941-945.
37. SPECK, D. F. & REVELETTE, W. R. (1987b). Excitation of dorsal and ventral respiratory group neurons by phrenic nerve afferents. Journal of Applied Physiology 62, 946-951.
38. SUPINSKI, G. S., DIMARCO, A. F., HUSSEIN, F. & ALTOSE, M. D. (1989). Alterations in respiratory muscle activation in the ischemic fatigued canine diaphragm. Journal of Applied Physiology 67, 720-729.
39. TEITELBAUM, J., VANELLI, G. & HUSSAIN, S. N. A. (1993). Thin-fiber phrenic afferents mediate the ventilatory response to diaphragmatic ischemia. Respiration Physiology 91, 195-206.
40. WOODS, J. J., FURBUSH, F. & BIGLAND-RITCHIE, B. (1987). Evidence for a fatigue-induced reflex inhibition of motoneuron firing rates. Journal of Neurophysiology 58, 125-137.