Alterations of the mucosal immune system in inflammatory bowel disease

Journal of Gastroenterology

Volumn 31, Issue 6, 1996, Pages 907-916

  MacDermott, Richard P ^a  

^a LAHEY HOSPITAL AND MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIUM LIPOPOLYSACCHARIDE; CHEMOKINE; CYTOKINE; HLA ANTIGEN CLASS 2; INTERLEUKIN 1; INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; INTERLEUKIN 10; INTERLEUKIN 4; INTERLEUKIN 6; INTERLEUKIN 8; MONOCYTE CHEMOTACTIC PROTEIN 1; PEPTIDOGLYCAN; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR ALPHA;

ANTIGEN PRESENTING CELL; B LYMPHOCYTE; BACTERIAL CELL WALL; CELL MIGRATION; ENDOTHELIUM CELL; ENTERITIS; EPITHELIUM CELL; FIBROBLAST; GRANULOCYTE; HUMAN; IMMUNE SYSTEM; INFLAMMATION; INTESTINE; LYMPHOCYTE ACTIVATION; MACROPHAGE; MUCOSA; PRIORITY JOURNAL; REVIEW; T LYMPHOCYTE;

ANIMALS; CYTOKINES; GRANULOCYTES; HUMANS; IMMUNOGLOBULINS; INFLAMMATORY BOWEL DISEASES; INTESTINAL MUCOSA; T-LYMPHOCYTES;

EID: 0030453548     PISSN: 09441174     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF02358624     Document Type: Review

References (84)

1. Mestecky J. The common mucosal immune system and current strategies for inducation of immune responses in external secretions. J Clin Immunol 1987;7:265-276.
2. Mestecky J, McGhee JR. Immunoglobulin A (IgA): Molecular and cellular interactions involved in IgA biosynthesis and immune response. Adv Immunol 1987,40:153-245.
3. MacDermott RP, Stenson WF. Alterations in the mucosal immune system in ulcerative colitis and Crohn's disease. Adv Immunol 1988;42:285-323.
4. MacDermott RP. Alterations in the mucosal immune system in ulcerative colitis and Crohn's disease. Med Clin North Am 1994;78:1207-1231.
5. Dinarello CA. Biology of interleukin-1. FASEB J 1988;2:108-115.
6. Kawanishi H, Saltzman LE, Strober W. Mechanisms regulating IgA class-specific immunoglobulin production in murine gut-associated lymphoid tissues. I. T cells derived from Peyer's patches that switch sIgM B cells in vitro. J Exp Med 1983; 157:433-450.
7. Kawanishi H, Saltzman L, Strober W. Mechanisms regulating IgA class-specific immunoglobulin production in murine gut-associated lymphoid tissues. II. Terminal differentiation of postswitch sIgA-bearing Peyer's patch B cells. J Exp Med 1983; 158:649-669.
8. Coffmann RL, Shrader B, Carty J, et al. A mouse T cell product that preferentially enhances IgA production. I. Biologic characterization. J Immunol 1987;139:3685-3690.
9. Brandtzaeg P, Sollid LM, Thrane PS, et al. Lymphoepithelial interactions in the human mucosal immune system. Gut 1988;29:1116-1130.
10. MacDermott RP, Nahm MH. Expression of human immunoglobulin G subclassed in inflammatory bowel disease. Gastroenterology 1987;93:1127-1129.
11. Scott MG, Nahm MH, Macke K, et al. Spontaneous secretion of IgG subclasses by intestinal mononuclear cells: Differences between ulcerative colitis. Cronhn's disease and controls. Clin Exp Immunol 1986;66.209-215.
12. MacDermott RP. Altered secretion patterns of IgA and IgG subclasses by IBD intestinal mononuclear cells. In: Geobell H, Peskar BM, Malchow H (eds) Inflammatory bowel diseases - basic research and clinical implications. Lancaster, England. MTP Press, 1988;105-111.
13. MacDermott RP, Nash GS, Auer IO, et al. Alterations in serum IgG subclasses in patients with ulcerative colitis and Crohn's disease (abstract). Gastroenterology 1989;94:A275.
14. Peters MG, Secrist H, Anders KR, et al. Normal human intestinal B lymphocytes: Increased activation compared to peripheral blood. J Clin Invest 1989;83:1827-1833.
15. Schreiber S, MacDermott RP, Raedler A, et al. Increased activation of isolated intestinal lamina propria mononuclear cells in inflammatory bowel disease Gastroenterology 1991;101:1020-1030.
16. Schreiber S, Nash GS, Raedler A, Pinnau R, Bertovich MJ, MacDermott RP. Human lamina propria mononuclear cells are activated in inflammatory bowel disease. In: Tsuchiya M (ed) Frontiers of mucosal immunology. Amsterdam: Elsevier, 1991; 749-753.
17. Schreiber S, Raedler A, Conn AR, et al. Increased in vitro release of soluble interleukin-2 receptor by colonic lamina propria mononuclear cells in inflammatory bowel disease. Gut 1992;33:236-241.
18. Van Spreeuwel JP, Lindeman J, Meijer ACJLM. A quantitative study of immunoglobulin-containing cells in the differential diagnosis of acute colitis. J Clin Pathol 1985;38:774-777.
19. Heiner DC. Significance of immunoglobulin G (IgG) subclasses. Am J Med 1984;76:1.
20. Oxelius VA. Immunoglobulin G (IgG) subclasses and human disease. Am J Med 1984,76:7-18.
21. Targan SR, Landers CJ, Cobb L, et al. Perinuclear anti-neutrophil cytoplasmic antibodies are spontaneously produced by mucosal B cells of ulcerative colitis patients. J Immunol 1995;155:3262-3267.
22. Halstensen TS, Mollnes TE, Brandtzaeg P. Persistent complement activation in submucosal blood vessels of active inflammatory bowel disease: Immunohistochemical evidence. Gastroenterology 1989;97:10-19.
23. Halstensen TS, Mollnes TE, Fausa O, Brandtzaeg P. Deposits of terminal complement complex (TCC) in muscular mucosa and submucosal vessels in ulcerative colitis and Crohn's disease of the colon. Gut 1989;30:361-366.
24. Ahrenstedt O, Knutson L, Nilsson B, et al. Enhanced local production of complement components in the small intestines of patient with Crohn's disease. N Engl J Med 1990;322:1345-1349.
25. Saverymuttu SH, Chadwick VS, Hodgson HJ. Granulocyte migration in ulcerative colitis. Eur J Clin Invest 1985;15:60-68.
26. Saverymuttu SH, Peters AM, Lavender JP, Chadwick VS, Hodgson JH. In vivo assessment of granulocyte migration to diseased bowel in Crohn's disease. Gut 1985;26:378-383.
27. 99mtechnetium hexamethyl propylene amine oxine as leukocyte label. Gastroenterology 1988;95:1287-1293.
28. 99mtechnetium phagocyte scanning. Gastroenterology 1988;95:989-996.
29. Isaacs KL, Sartor RB, Haeskil JS. Cytokine messenger RNA profiles in inflammatory bowel disease mucosa detected by polymerase chain reaction amplification. Gastroenterology 1992;103: 1587-1595.
30. Stevens C, Walz G, Zanker B. Interleukin-6, interleukin-1-beta and tumor necrosis factor: Expression in inflammatory bowel disease (abstract). Gastroenterology 1990;98:A475.
31. Mahida YR, Wu K, Jewell DP. Enhanced production of interleukin-1-beta by mononuclear cells isolated from mucosa with active ulcerative colitis or Crohn's disease. Gut 1989;30:835-838
32. Cominelli F, Dinarello CA. Interleukin-1 in the pathogenesis of and protection from inflammatory bowel disease. Biotherapy 1989;1:369-375.
33. Cominelli F, Nast CC, Clark BD, et al. Interleukin-1 (IL-1) gene expression, synthesis and effect of specific IL-1 receptor blockade in rabbit immune complex colitis. J Clin Invest 1990;86:972-980.
34. Reinecker H-C, Steffen M, Witthoeft T, et al. Enhanced secretion of TNF-alpha, IL-6, and IL-1-beta by isolated lamina propria mononuclear cells from patients with ulcerative colitis and Crohn's disease. Clin Exp Immunol 1993;94:174-181.
35. MacDonald TT, Choy MY, Hutchings P, Cooke A. Activated T cells and macrophages in the intestinal mucosa of children with inflammatory bowel disease. In: MacDonald TT, Chalacombe SJ, Bland PW, Stokes CR, Heatley RV, Mowat AM (eds) Advances in mucosal immunology. Boston: Kluwer, 1990;683-690.
36. MacDonald TT, Hutchings P, Choy MY, et al. Tumor necrosis factor-alpha and interferon-gamma production measured at the single-cell level in normal and inflamed human intestine. Clin Exp Immunol 1990;81:301-305.
37. Borgeat P, Samuelsson B. Transformation of arachidonic acid by rabbit polymorphonuclear leukocytes. J Biol Chem 1979;254: 2643-2646
38. Stenson WF, Parker CW. Leukotrienes. Adv Intern Med 1984; 30:175-199.
39. Sharon P, Stenson WF. Enhanced synthesis of leukotriene B4 by colonic mucosa in inflammatory bowel disease. Gastroenterology 1984;86:453-460.
40. Lauritsen K, Laursen LS, Bukhave K, Rask-Madsen J. Effects of systemic prednisolone on arachidonic acid metabolites determined by equilibrium in vivo dialysis of rectum in severe relapsing ulcerative colitis (abstract). Gastroenterology 1985; 88:A1466.
41. Ford-Hutchinson WW, Bray MA, Doig MV. Leukotriene B, a potent chemotactic and aggregating substance released from polymorphonuclear leukocytes. Nature 1984;266:264-265.
42. Yoshimura T, Matsushima K, Oppenheim JJ, Leonard EJ. Neutrophil chemotactic factor produced by lipopolysaccharide (LPS)-stimulated human blood mononuclear leukocytes: Partial characterization and separation from interleukin-1 (IL-1). J Immunol 1987;139:788-793.
43. Oppenheim JJ, Zachariae CO, Mukaida N, Matsushima K. Properties of the novel proinflammatory supergene intercrine cytokine family. Annu Rev Immunol 1991;9:617-648.
44. Baggiolini M, Walz A, Kunkel SL. Neutrophil-activating peptide-1/interleukin-8: A novel cytokine that activates neutrophils. J Clin Invest 1989;84:1045-1049.
45. Baggiolini M, Dewald B, Moser B. Interleukin-8 and related chemotactic cytokines - CXC and CC chemokines Adv Immunol 1994;55:97-179.
46. Matsushima K, Morishita K, Yoshimura T, et al. Molecular cloning of human monocyte-derived neutrophil chemotactic factor (MDNCF) and induction of MDNCF mRNA by interleukin-1 and tumor necrosis factor. J Exp Med 1988;167:1883-1893.
47. Standiford TJ, Kunkel SL, Basha MA, et al. Interleukin-8 gene expression by a pulmonary epithelial cell line. A model for cytokine network in the lung. J Clin Invest 1990;86:1945-1953.
48. Miller MD, Krangel MS. Biology and chemistry of the chemokines: A family of chemotactic and inflammatory cytokines. Crit Rev Immunol 1992;12:17-46.
49. Yoshimura T, Leonard EJ. Human monocyte chemoattractant protein-1 (MCP-1). Adv Exp Med Biol 1991;305:47-56.
50. Loetscher P, Seitz M, Clark-Lewis I, et al. Monocyte chemotactic proteins MCP-1, MCP-2, and MCP-3 are major attractants for human CD4+ AND CD8+ T lymphocytes. FASEB J 1994;8:1055-1060.
51. Barker JN, Sarma V, Mitra RS, et al. Marked synergism between tumor necrosis factor-alpha and interferon-gamma in regulation of keratinocyte-derived adhesion molecules and chemotactic factors. J Clin Invest 1990;85:605-608.
52. Tobler A, Meier R, Seitz M, et al. Glucocorticoids downregulate gene expression of GM-CSF, NAP-1/IL-8, and IL-6, but not of M-CSF in human fibroblasts. Blood 1992;79:45-51.
53. Standiford TJ, Strieter RM, Kasahara K, Kunkel SL. Disparate regulation of interleukin 8 gene expression from blood monocytes, endothelial cells, and fibroblasts by interleukin 4. Biochem Biophys Res Commun 1990;171:531-536.
54. Yoshimura T, Leonard EJ. Secretion by human fibroblasts of monocyte chemoattractant protein-1. the product of gene JE. J Immunol 1990;144:2377-2383.
55. Albelda SM, Smith CW, Ward PA. Adhesion molecules and inflammatory injury. FASEB J 1994;8:504-512.
56. Springer TA. Traffic signals for lymphocyte recirculation and leukocyte emigration: The multistep paradigm. Cell 1994;76:301-314.
57. Albelda SM, Buck CA. Integrins and other cell adhesion molecules. FASEB J 1990;4:2868-2880.
58. Butcher EC. Leukocyte-endothelial cell recognition: Three (or more) steps to specificity and diversity. Cell 1991;67:1033-1036.
59. Bevilacqua M, Nelson RM. Selectins J Clin Invest 1993;91:379-387.
60. Lasky LA. Selectins: Interpreters of cell-specific carbohydrate information during inflammation. Science 1992;258:964-969.
61. Rollins BJ, Walz A, Baggiolini M. Recombinant human MCP-1/ JE induces chemotaxis, calcium flux, and the respiratory burst in human monocytes. Blood 1991;78:1112-1116.
62. Kelvin DJ, Michiel DF, Johnston JA, et al. Chemokines and serpentines: The molecular biology of chemokine receptors. J Leukoc Biol 1993;54:604-612.
63. Grob PM, David E, Warren TC, et al. Characterization of a receptor for human monocyte-derived neutrophil chemotactic factor/interleukin-8. J Biol Chem 1990;265:8311-8316.
64. Samanta AK, Oppenheim JJ, Matsushima K. Interleukin-8 (monocyte-derived neutrophil chemotactic factor) dynamically regulates its own receptor expression on human neutrophils J Biol Chem 1990;265-183-189.
65. Holmes WE, Lee J, Kuang WJ, et al. Structure and functional expression of a human interleukin-8 receptor. Science 1991; 253:1273-1280.
66. Murphy PM, Tiffany HL. Cloning of complementary DNA encoding a functional human interleukin-8 receptor. Science 1991;253:1280-1283.
67. Yoshimura T, Leonard EJ. Identification of high affinity receptors for human monocyte chemoattractant protein-1 on human monocytes. J Immunol 1990;145:292-297.
68. Lee J, Horuk R, Rice GC, et al. Characterization of two high affinity human interleukin-8 receptors. J Biol Chem 1992;267: 16283-16287.
69. Gayle RB 3d, Sleath PR, Srinivason S, et al. Importance of the amino terminus of the interleukin-8 receptor in ligand interactions. J Biol Chem 1993;268:7283-7289.
70. Ahuja SK, Gao JL, Murphy PM. Chemokine receptors and molecular mimicry. Immunol Today 1994;15:281-287.
71. Wang JM, Sherry B, Fivash MJ, et al. Human recombinant macrophage inflammatory protein-1 alpha and -beta and monocyte chemotactic and activating factor utilize common and unique receptors on human monocytes J Immunol 1993;150. 3022-3029.
72. Oh KO, Zhou Z, Kim KK, et al. Identification of cell surface receptors for murine macrophage inflammatory protein-1 alpha. J Immunol 1991;147:2978-2983.
73. Wang JM, McVicar DW, Oppenheim JJ, Kelvin DJ. Identification of RANTES receptors on human monocytic cells: Competition for binding and desensitization by homologous chemotactic cytokines. J Exp Med 1993;177:699-705.
74. Schroöder JM. Generation of NAP-1 and related peptides in psoriasis and other inflammatory skin diseases Cytokines 1992; 4:54-76.
75. Seitz M, Dewald B, Gerber N, Baggiolini M. Enhanced production of neutrophil-activating peptide-1/interleukin-8 rheumatoid arthritis. J Clin Invest 1991;87:463-469.
76. Rampart M, Herman AG, Grillet B, et al. Development and application of a radioimmunoassay for interleukin-8: Detection of interleukin-8 in synovial fluids from patients with inflammatory joint disease. Lab Invest 1992;66:512-518.
77. Koch AE, Kunkel SL, Harlow LA, et al Enhanced production of monocyte chemoattractant protein-1 in rheumatoid arthritis. J Clin Invest 1992;90:772-779.
78. Carre PC, Mortenson RL, King TE Jr, et al. Increased expression of the interleukin-8 gene by alveolar macrophages in idiopathic pulmonary fibrosis. A potential mechanism for the recruitment and activation of neutrophils in lung fibrosis. J Clin Invest 1991,88:1802-1810.
79. Mahida YR, Ceska M, Effenberger F, et al. Enhanced synthesis of neutrophil-activating peptide-1/interleukin-8 in active ulcerative colitis. Clin Science 1992;82:273-275.
80. Izzo RS, Witkon K, Chen AI, et al. Interleukin-8 and neutrophil markers in colonic mucosa from patients with UC. Am J Gastroenterol 1992;87:1447-1452.
81. Hommes DW, Jansen J, Smit F, et al. Enhanced production of interleukin-8 in ulcerative colitis. Gastroenterology 1992;102: A927.
82. Izutani R, Ohyanagi H, MacDermott RP. Quantitative PCR for detection of femtogram quantities of interleukin-8 mRNA expression. Microbiol Immunol 1994,38:233-237.
83. Izutani R, Loh EY, Reinecker H-C, et al. Increased expression of interleukin-8 mRNA in ulcerative colitis and Crohn's disease mucosa and epithelial cells. Inflamm Bowel Dis 1995; 1:37-47.
84. Reinecker HC, Loh EY, Ringler DJ, et al. Monocyte-chemoattractant protein 1 gene expression in intestinal epithelial cells and inflammatory bowel disease mucosa. Gastroenterology 1995;108:40-50.