In vitro formation of cysts derived from a rat model of autosomal dominant polycystic kidney disease

Nephrology Dialysis Transplantation

Volumn 11, Issue SUPPL. 6, 1996, Pages 58-61

  Pey, R ^a,b   Hafner, M ^b   Schieren, G ^c   Bach, J ^b,c   Gretz, N ^c  

^a UNIVERSITY OF CHILE   (Chile)

^b Tech University of Applied Sciences   (Germany)

^c UNIVERSITY OF HEIDELBERG   (Germany)

Author keywords

Cell culture; Confocal microscopy; Epidermal growth factor; Polycystic kidney disease; Taxol

Indexed keywords

EPIDERMAL GROWTH FACTOR; PACLITAXEL;

ANIMAL MODEL; AUTOSOMAL DOMINANT DISORDER; CONFERENCE PAPER; KIDNEY POLYCYSTIC DISEASE; NONHUMAN; PATHOPHYSIOLOGY; PRIORITY JOURNAL; RAT;

EID: 0030453501     PISSN: 09310509     EISSN: None     Source Type: Journal    
DOI: 10.1093/ndt/11.supp6.58     Document Type: Conference Paper

References (31)

1. Welling LW, Grantham J. Cystic developmental diseases of the kidney. In: Brenner BM, Rector C, eds. The kidney. WB Saunders, Philadelphia, PA, 1991; 1657
2. Carone FA, Bacallao R, Kanwar YS. Biology of disease: biology of polycystic kidney disease. Lab Invest 1994; 70: 437-448
3. Nadasky T, Laszik Z, Lajoie G, Blick KF, Wheeler DE, Silva F. Proliferative activity of cyst epithelium in human renal cystic diseases. J Am Soc Nephrol 1995; 5: 1462-1468
4. +-ATPase: mislocation to apical plasma membrane in polycystic kidney disease epithelia. Am J Physiol 260 (Renal fluid electrolyte physiology) 1991; 29: F420-F430
5. Grantham JJ. Fluid secretion, cellular proliferation, and the pathogenesis of renal epithelial cysts. J Am Soc Nephrol 1993; 3: 1843-1857
6. Carone FA, Nakamura S, Caputo M, Bacallao R, Nelson WJ, Kanwar YS. Cell polarity in human renal cystic disease. Lab Invest 1994; 70: 648-655
7. International PKD Consortium. Polycystic kidney disease: the complete structure of the PKD1 gene and its protein. Cell 1995; 81: 289-298
8. Gretz N, Kränzlin B, Pey R, Schieren G, Bach J, Obermüller, N, Ceccerini I, Klölting I, Rohmeiss, P, Bachmann S, Hafner, M. Rat models of autosomal dominant polycystic kidney disease. Nephrol Dial Transplant 1996; 11 [Suppl. 6]: 46-51
9. Schieren G, Pey R, Bach J, Hafner M, Gretz N. Murine models of polycystic kidney disease. Nephrol Dial Transplant 1996; 11 [Suppl. 6]: 38-45
10. Gattone VH, Grantham JJ. Understanding human cystic disease through experimental models. Semin Nephrol 1991; 11: 617-631
11. Neufeld TK, Douglass D, Grant M et al. In vitro formation and expansion of cysts derived from human renal cortex epithelial cells. Kidney Int 1992; 41: 1222-1236
12. +-ATPase in polarized epithelial cells. Science 1991; 254: 847-850
13. Wang AZ, Ojakian CF, Nelson WJ. Steps in the morphogenesis of a polarized epithelium. I. Uncoupling the roles of cell-cell and cell-substratum contact in establishing plasma membrane polarity in multicellular epithelial (MDCK) cysts. J Cell Sci 1990; 95: 137-151
14. Mangoo-Karim R, Grantham JJ. Transepithelial water permeability in an in vitro model of renal cysts. J Am Soc Nephrol 1990; 1: 278-285
15. Avner ED. Epithelial polarity and differentiation in polycystic kidney disease. J Cell Sci 1993; 17 (suppl): 217-222
16. Woo DDL, Miao SYP, Pelayo JC, Woolf A. Taxol inhibits progression of congenital polycystic kidney disease. Nature 1994; 368: 750-753
17. Preminger GM, Koch WF, Fried FA, McFarland, Murphy ED, Mandell J. Murine congenital polycystic kidney disease: a model for studying development of cystic disease. J Urol 19821; 27: 556-560
18. Flaherty L, Bryda FC, Collins D, Rudofsky U, Montgomery JC. New mouse model for polycystic kidney disease with both recessive and dominant gene effects. Kidney Int 1995; 47: 552-558
19. Takahashi H, Calvet JP, Dittemore-Hoover D, Yoshida K, Grantham JJ, Gattone VH. A hereditary model of slowly progressive polycystic kidney disease in the mouse. J Am Soc Nephrol 1991; 1: 980-989
20. Atala A, Freeman MR, Mandell J, Beler DR, Juvenile cystic kidneys (jck): a new mutation which causes polycystic kidneys. Kidney Int 1993; 43: 1081-1085
21. Nauta J, Ozawa Y, Sweeney WF, Rutledge JC, Avner FD. Renal and biliary abnormalities in a new murine model of autosomal recessive polycystic kidney disease. Pediatr Nephrol 1993; 7: 163-172
22. Kaspareit-Rittinghausen J, Deerberg F, Rapp K, Wcislo A. A new rat model for polycystic kidney disease of humans. Transplant Proc 1990; 22: 2582-2583
23. Bachmann S, Ramasubbu K, Schäfer K, Uiker S, Gretz N. Tubulo-interstitial changes in the HAN:SPRD rat model for autosomal dominant polycystic kidney disease. Contrib Nephrol 1995; 115: 113-117
24. Schäfer K, Bader M, Gretz N, Oberbäumer I, Bachmann S. Focal overexpression of collagen IV characterizes the initiation of epithelial changes in polycystic kidney disease. Exp Nephrol 1994; 2: 190-195
25. Gretz N, Haisch S, Baur S et al. Models of polycystic kidney disease in the rat. In: Gretz N, Strauch M, eds. Experimental and genetic rat models of chronic renal failure. Karger, Basel, 1993; 115-123
26. Gretz N. Progression of chronic renal failure in a rat strain with autosomal dominant polycystic kidney disease. Nephron 1994; 68: 462-467
27. Schäfer K, Gretz N, Bader M et al. Characterization of the Han:SPRD rat model for hereditary polycystic kidney disease. Kidney Int 1994; 46: 134-152
28. McAteer JA, Evan AP, Gardner KD. Morphogenetic clonal growth of kidney epithelial cell line MDCK. Anat Rec 1987; 217: 229-239
29. Nelson WJ. Regulation of cell surface polarity in renal epithelia. Pediatr Nephrol 1993; 7: 599-604
30. Schiff PB, Horwitz SB. Taxol stabilizes microtubules in mouse fibroblast cells. Proc Natl Acad Sci 1980; 77: 1561-1565
31. Gelmon K. The taxoids: paclitaxel and docetaxel. The Lancet 1994; 344: 1267-1272