Pertussis toxin-insensitive effects of mastoparan, a wasp venom peptide, in PC12 cells

Journal of Cellular Physiology

Volumn 169, Issue 3, 1996, Pages 448-454

  Murayama, Toshihiko ^a   Oda, Haruko ^a   Nomura, Yasuyuki ^a  

^a HOKKAIDO UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE DIPHOSPHATE RIBOSYLATION FACTOR; CARBACHOL; CHOLERA TOXIN; CYCLIC AMP; FORSKOLIN; MASTOPARAN; PERTUSSIS TOXIN;

ANIMAL CELL; ARTICLE; CELL METABOLISM; CELL STRAIN; CONTROLLED STUDY; DOSE RESPONSE; DRUG TOXICITY; IN VITRO STUDY; NONHUMAN; NORADRENALIN RELEASE; PHEOCHROMOCYTOMA; PRIORITY JOURNAL; RAT;

ADENOSINE DIPHOSPHATE RIBOSE; ADP-RIBOSYLATION FACTORS; ANIMALS; CALCIUM; CARBACHOL; CHOLERA TOXIN; CYCLIC AMP; EXOCYTOSIS; GTP-BINDING PROTEINS; INSULIN; NOREPINEPHRINE; PC12 CELLS; PEPTIDES; PERTUSSIS TOXIN; RATS; VIRULENCE FACTORS, BORDETELLA; WASP VENOMS;

ANIMALIA; BACTERIA (MICROORGANISMS); BOVINAE; VESPIDAE;

EID: 0030453373     PISSN: 00219541     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-4652(199612)169:3<448::AID-JCP5>3.0.CO;2-O     Document Type: Article

References (45)

1. 2 activity by mastoparans, a new class of mast cell degranulating peptides from wasp venom. J. Biol. Chem. 258:13697-13702.
2. Beron, W., Colombo, M.I., Mayorga, L.S., and Stahl, P.D. (1995) In vitro reconstitution of phagosome-endosome fusion: Evidence for regulation by heterotrimeric GTPases. Arch. Biochem. Biophys., 317:337-342.
3. Choi, O.H., Padgett, W.L., and Daly, J.W. (1992) Effects of the amphiphilic peptides melittin and mastoparan on calcium influx, phosphoinositide breakdown and arachidonic acid release in rat pheochromocytoma PC12 cells. J. Pharmacol. Exp. Ther., 260:369-375.
4. s regulation of endosome fusion suggests a role for signal transduction pathways in endocytosis. J. Biol. Chem., 269:14919-14923.
5. Colombo, M.I., Mayorga, L.S., Casey, P.J., and Stahl, P.D. (1992) Evidence of a role for heterotrimeric GTP-binding proteins in endosome fusion. Science, 255:1695-1697.
6. Di Virgilio, F., Milani, D., Leon, A., Meldolesi, J., and Pozzan, T. (1987) Voltage-dependent activation and inactivation of calcium channels in PC12 cells. J. Biol. Chem., 262:9189-9195.
7. Donaldson, L.G., Cassel, D., Kahn, R.A., and Klausner, R.D. (1992) ADP-ribosylation factor, a small GTP-binding protein, is required for binding of the coatomer protein β-COP to Golgi membranes. Proc. Natl. Acad. Sci. U.S.A., 89:6408-6412.
8. D'Souza-Schorey, C., Li, G., Colombo, M.I., and Stahl, P.D. (1995) A regulatory role for ARF6 in receptor-mediated endocytosis. Science, 267:1175-1178.
9. E: A GTP-binding protein mediating exocytosis. Annu. Rev. Physiol., 52:591-606.
10. o by mastoparan, related amphiphilic peptides, and hydrophobic amines. J. Biol. Chem., 265:14176-14186.
11. Higashijima, T., Uzu, S., Nakajima, T., and Ross, E.M. (1988) Mastoparan, a peptide toxin from wasp venom, mimics receptors by activating GTP-binding regulatory proteins (G proteins). J. Biol. Chem., 263:6491-6494.
12. Hirai, Y., Yasuhara, T., Yoshida, H., Nakajima, T., Fujino, M., and Kitada, C. (1979) A new mast cell degranulating peptide "mastoparan" in the venom of Vespula lewisii. Chem. Pharmacol. Bull. 27:1942-1944.
13. Honma, M., Satoh, T., Takezawa, J., and Ui, M. (1977) An ultrasensitive method for the simultaneous determination of cyclic AMP and cyclic GMP in small-volume samples from blood and tissue. Biochem. Med., 18:257-273.
14. Joyce-Brady, M., Rubins, J.B., Panchenko, M.P., Bernardo, J., Steele, M.P., Kolm, L., Simons, E.R., and Dickey, B.F. (1991) Mechanisms of mastoparan-stimulated surfactant secretion from isolated pulmonary alveolar type 2 cells. J. Biol. Chem., 266:6859-6865.
15. Kahn, R.A., and Gilman, A.G. (1984) Purification of a protein cofactor required for ADP-ribosylation of the stimulatory regulatory component of adenylate cyclase by cholera toxin. J. Biol. Chem., 259:6228-6234.
16. s by cholera toxin is itself a GTP binding protein. J. Biol. Chem., 261:7906-7911.
17. Kikkawa, S., Takahashi, K., Takahashi, K., Shimada, N., Ui, M., Kimura, N., and Katada, T. (1992) Activation of nucleoside diphosphate kinase by mastoparan, a peptide isolated from wasp venom. FEBS Lett., 305:237-240.
18. Komatsu, M., Aizawa, T., Yokokawa, N., Sato, Y., Okada, N., Takasu, N., and Yamada, T. (1992) Mastoparan-induced hormone release from rat pancreatic islets. Endoclinology, 130:221-228.
19. 2+-independent late site in stimulus-secretion coupling. J. Biol. Chem., 268:23297-23306.
20. Ktistakis, N.T., Linder, M.E., and Roth, M.G. (1992) Action of brefeldin A blocked by activation of a pertussis-toxin-sensitive G protein. Nature, 356:344-356.
21. Kuroda, Y., Yoshida, M., Kumakura, K., Kobayashi, K., and Nakajima, T. (1980) Effects of peptides on the release of catecholamines and adenine-nucleotides from adrenal chromaffin cells. Proc. Jpn. Acad., 56:660-664.
22. 2+, and secretion of noradrenaline in PC12 cells treated with glutamate. FEBS Lett., 270:225-228.
23. Lenhard, J.M., Colombo, M.I., and Stahl, P.D. (1994) Heterotrimeric GTP-binding proteins (G proteins) and ADP-ribosylation factor (ARF) regulate proming of endosomal membranes for fusion. Arch. Biochem. Biophys., 312:474-479.
24. Leyte, A., Barr, F.A., Kehlenbach, R.H., and Huttner, W.B. (1992) Multiple trimeric G-proteins on the trans-Golgi network exert stimulation and inhibitory effects on secretory vesicle formation. EMBO J., 11:4795-4804.
25. Martin, P.T., and Koshland, Jr. D.E. (1992) Regulation of neurosecretory habituation in PC12 cells: Parallel pathways used by cAMP and calcium. Proc. Natl. Acad. Sci. U.S.A., 89:10257-10261.
26. Morgan, A., and Burgoyne, R.D. (1993) A synthetic peptide of the N-terminus of ADP-ribosylation factor (ARF) inhibits regulated exocytosis in adrenal chromaffin cells. FEBS Lett., 329:121-124.
27. Moss, J., and Vaughan, M. (1988) ADP-Ribosylation of guanyl nucleotide-binding regulatory proteins by bacterial toxins. Adv. Enzymol., 61:303-379.
28. Mousli, M., Bronner, C., Bueb, J.-L., Tschirhart, E., Gies, J.-P., and Landry, Y. (1989) Activation of rat peritoneal mast cells by substance P and mastoparan. J. Pharmacol. Exp. Ther., 250:329-335.
29. Murayama, T., Tsai, S.-C., Adamik, R., Moss, J., and Vaughan, M. (1993) Effects of temperature on ADP-ribosylation factor stimulation of cholera toxin activity. Biochemistry, 32:561-566.
30. 3H]-noradrenaline from PC12 cells. J. Biochem., 118:325-331.
31. i elevation or noradrenaline release in PC12 cells. Arch. Biochem. Biophys., 332:1-7.
32. o, in the mechanism of exocytosis in adrenal chromaffin cells. J. Neurochem., 58:2275-2284.
33. Okano, Y., Takagi, H., Tohmatsu, T., Nakashima, S., Kuroda, Y., Saito, K., and Nozawa, Y. (1985) A wasp venom mastoparan-induced polyphosphoinositide breakdown in rat peritoneal mast cells. FEBS Lett., 188:363-366.
34. Ozaki, Y., Mastumoto, Y., Yatomi, Y., Higashihara, M., Kariya, T., and Kume, S. (1990) Mastoparan, a wasp venom, activates platelets via pertussis toxin-sensitive GTP-binding proteins. Biochem. Biophys. Res. Commun., 170:779-785.
35. Rothman, J.E., and Orci, L. (1992) Molecular dissection of the secretory pathway. Nature, 355:409-415.
36. Sela, D., Ram, E., and Atlas, D. (1991) ATP receptor; A putative receptor-operated channel in PC-12 cells. J. Biol. Chem., 266:17990-17994.
37. Sontag, J.-M., Thierse, D., Rouot, B., Aunis, D., and Bader, M.-F. (1991) A pertussis-toxin-sensitive protein controls exocytosis in chromaffin cells at a step distal to the generation of second messengers. Biochem. J., 274:339-347.
38. Stahl, B., Mollard, G.F., Walch-Solimena, C., and Jahn, R. (1994) GTP cleavage by the small GTP-binding protein Rab3A is associated with exocytosis of synaptic vesicles induced by α-latrotoxin. J. Biol. Chem., 269:24770-24776.
39. Tomita, U., Inanobe, A., Kobayashi, I., Takahashi, K., Ui, M., and Katada, T. (1991) Direct interactions of mastoparan and compound 48/80 with GTP-binding proteins. J. Biochem. (Tokyo), 109:184-189.
40. Vitale, N., Mukai, H., Rouot, B., Thierse, D., Aunis, D., and Bader, M.-F. (1993) Exocytosis in chromaffin cells. J. Biol. Chem., 268:14715-14723.
41. Walker, M.W., Bobak, D.A., Tsai, S.-C., Moss, J., and Vaughan, M. (1992) GTP but not GDP analogues promote association of ADP-ribosylation factors, 20-kDa protein activators of cholera toxin, with phospholipids and PC-12 cell membranes. J. Biol. Chem., 267:3230-3235.
42. Wheeler-Jones, C.P.D., Saermark, T., Kakkar, V.V., and Authi, K.S. (1992) Mastoparan promotes exocytosis and increases intracellular cyclic AMP in human platelets. Biochem. J., 281:465-472.
43. Wilson, S.P. (1989) Effects of mastoparan on catecholamine release from chromaffin cells. FEBS Lett., 247:239-241.
44. Yokokawa, N., Komatsu, M., Takeda, T., Aizawa, T., and Yamada, T. (1989) Mastoparan, a wasp venom, stimulates insulin release by pancreatic islets through pertussis toxin sensitive GTP-binding protein. Biochem. Biophys. Res. Commun., 158:712-716.
45. Zhang, J., King, W.G., Dillon, S., Hall, A., Feig, L., and Rittenhouse, S.E. (1993) Activation of platelet phosphatidylinositide 3-kinase requires the small GTP-binding protein Rho. J. Biol. Chem., 268:22251-22254.