Postsynaptic currents and short-term synaptic plasticity in Purkinje cells grafted onto an uninjured adult cerebellar cortex

European Journal of Neuroscience

Volumn 8, Issue 12, 1996, Pages 2690-2701

  Tempia, Filippo ^a   Bravin, Monica ^a   Strata, Piergiorgio ^a  

^a UNIVERSITY OF TURIN   (Italy)

Author keywords

Cerebellum; Climbing fibre; Neural transplantation; Patch clamp; Rat

Indexed keywords

4 AMINOBUTYRIC ACID A RECEPTOR;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN ELECTROPHYSIOLOGY; CELL TRANSPLANTATION; CEREBELLUM CORTEX; EMBRYO; EXCITATORY POSTSYNAPTIC POTENTIAL; NERVE CELL PLASTICITY; NONHUMAN; PATCH CLAMP; PRIORITY JOURNAL; PURKINJE CELL; RAT;

ANIMALS; CELL MOVEMENT; CEREBELLAR CORTEX; ELECTRIC CONDUCTIVITY; ELECTROPHYSIOLOGY; GAMMA-AMINOBUTYRIC ACID; NEURONAL PLASTICITY; PATCH-CLAMP TECHNIQUES; PURKINJE CELLS; RATS; RATS, WISTAR; SYNAPSES; TIME FACTORS;

EID: 0030452996     PISSN: 0953816X     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1460-9568.1996.tb01564.x     Document Type: Article

References (47)

1. Armengol, J. A., Sotelo, C., Angaut, P. and Alvarado-Mallart, R.-M. (1989) Organization of host afferents to cerebellar grafts implanted into kainate lesioned cerebellum in adult rats. Eur. J. Neurosci., 1, 75-93.
2. Björklund, A. (1991) Neural transplantation. An experimental tool with clinical possibilities. Trends Neurosci., 14, 319-322.
3. Björklund, A., Bickford, P., Dahl, D., Hoffer, B. and Olson, L. (1984) Intracranial cerebellar grafts: intermediate filament immunocytochemistry and electrophysiology. Exp. Brain Res., 55, 372-385.
4. Blackstone, C., Murphy, T. H., Moss, S. J., Baraban, J. M. and Huganir, R. L. (1994) Cyclic AMP and synaptic activity-dependent phosphorylation of AMPA-preferring glutamate receptors. J. Neurosci., 14, 7585-7593.
5. Bravin, M., Rossi, F. and Strata, P. (1995) Different climbing fibres innervate separate dendritic regions of the same Purkinje cell in hypogranular cerebellum. J. Comp. Neurol., 357, 395-407.
6. Chen, C., Kano, M., Abeliovich, A., Chen, L., Bao, S., Kim, J. J., Hashimoto, K., Thompson, R. F. and Tonegawa, S. (1995) Impaired motor coordination correlates with persistent multiple climbing fiber innervation in PKCγ mutant mice. Cell, 83, 1233-1242.
7. Clark, K. A., Randall, A. D. and Collingridge, G. L. (1994) A comparison of paired-pulse facilitation of AMPA and NMDA receptor-mediated excitatory postsynaptic currents in the hippocampus. Exp. Brain Res., 101, 272-278.
8. Crepel, F., Mariani, J. and Delhaye-Bouchaud, N. (1976) Evidence for a multiple innervation of Purkinje cells by climbing fibers in immature rat cerebellum. J. Neurobiol., 7, 567-578.
9. Dumas, T. C. and Foster, T. C. (1995) Developmental increase in CA3-CA1 presynaptic function in the hippocampal slice. J. Neurophysiol., 73, 1821-1828.
10. Eccles, J. C., Llinás, R. and Sasaki, K. (1966a) The excitatory synaptic action of climbing fibres on the Purkinje cells of the cerebellum. J. Physiol. (Lond.), 182, 268-296.
11. Eccles, J. C., Llinás, R. and Sasaki, K. (1966b) Parallel fibre stimulation and the responses induced thereby in the Purkinje cells of the cerebellum. Exp. Brain Res., 1, 17-39.
12. Eccles, J. C., Llinás, R., Sasaki, K. and Voorhoeve, P. E. (1966c) Interaction experiments on the responses evoked in Purkinje cells by climbing fibres. J. Physiol. (Lond.), 182, 297-315.
13. Edwards, F. A, Konnerth, A., Sakmann, B. and Takahashi, T. (1989) A thin slice preparation for patch-clamp recordings from neurones of the mammalian central nervous system. Pflügers Arch., 414, 600-612.
14. Farrant, M. and Cull-Candy, S. G. (1991) Excitatory amino acid receptor-channels in Purkinje cells in thin cerebellar slices. Proc. R. Soc. Lond. B, 244, 179-184.
15. Gardette, R., Alvarado-Mallart, R. M., Crepel, F. and Sotelo, C. (1988) Electrophysiological demonstration of a synaptic integration of transplanted Purkinje cells into the cerebellum of the adult Purkinje cell degeneration mutant mouse. Neuroscience, 24, 777-789.
16. Gardette, R., Crepel, F., Alvarado-Mallart, R. M. and Sotelo, C. (1990) Fate of grafted embryonic Purkinje cells into the cerebellum of the adult 'Purkinje cell degeneration' mutant mouse. II. Development of synaptic responses: an in vitro study. J. Comp. Neurol., 295, 188-196.
17. Hamill, O. P., Marty, A., Neher, E., Sakmann, B. and Sigworth, F. J. (1981) Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches. Pflügers Arch., 391, 85-100.
18. Hounsgaard, J. and Yarom, Y. (1985) Intrinsic control of electroresponsive properties of transplanted mammalian brain neurons. Brain Res., 335, 372-376.
19. Ito, M. (1984) The Cerebellum and Neural Control. Raven Press, New York.
20. 2+ and short-term synaptic plasticity. Nature, 371, 603-606.
21. Kano, M., Hashimoto, K., Chen, C., Abeliovich, A., Aiba, A., Kurihara, H., Watanabe, M., Inoue, Y. and Tonegawa, S. (1995) Impaired synapse elimination during cerebellar development in PKCγ mutant mice. Cell, 83, 1223-1231.
22. Kashiwabuchi, N., Ikeda, K., Araki, K., Hirano, T., Shibuki, K., Takayama, C., Inoue, Y., Kutsuwada, T., Yagi, T., Kang, Y., Aizawa, S. and Mishina, M. (1995) Impairment of motor coordination, Purkinje cell synapse formation, and cerebellar long-term depression in GluRγ2 mutant mice. Cell, 81, 245-252.
23. Katz, B. and Miledi, R. (1968) The role of calcium in neuromuscular facilitation. J. Physiol. (Lond.), 195, 481-492.
24. Konnerth, A., Llano, I. and Armstrong, C. M. (1990) Synaptic currents in cerebellar Purkinje cells. Proc. Natl Acad. Sci. USA, 87, 2662-2665.
25. Llano, I., Leresche, N. and Marty, A. (1991a) Calcium entry increases the sensitivity of cerebellar Purkinje cells to applied GABA and decreases inhibitory synaptic currents. Neuron, 6, 565-574.
26. Llano, I., Marty, A., Armstrong, C. M. and Konnerth, A. (1991b) Synaptic-and agonist-induced excitatory currents of Purkinje cells in rat cerebellar slices. J. Physiol. (Lond.), 434, 183-213.
27. Mintz, I. M., Sabatini, B. L. and Regehr, W. G. (1995) Calcium control of transmitter release at a cerebellar synapse. Neuron, 15, 675-688.
28. Perkel, D. J., Hestrin, S., Sah, P. and Nicoll, R. A. (1990) Excitatory synaptic currents in Purkinje cells. Proc. R. Soc. Lond. B, 241, 116-121.
29. - currents in Purkinje versus granule neurons in rat cerebellar slices. Neuron, 12, 117-126.
30. Roche, K. W., Tingley, W. G. and Huganir, R. L. (1994) Glutamate receptor phosphorylation and synaptic plasticity. Curr. Opin. Neurobiol., 4, 383-388.
31. Rossi, F. and Strata, P. (1995) Reciprocal trophic interactions in the adult climbing fibre-Purkinje cell system. Progr. Neurobiol., 47, 341-369.
32. Rossi, F., Borsello, T. and Strata, P. (1992) Embryonic Purkinje cells grafted on the surface of the cerebellar cortex integrate in the adult unlesioned cerebellum. Eur. J. Neurosci., 4, 589-593.
33. Rossi, F., Borsello, T. and Strata, P. (1994) Embryonic Purkinje cells grafted on the surface of the adult uninjured rat cerebellum migrate in the host parenchyma and induce sprouting of intact climbing fibres. Eur. J. Neurosci., 6, 121-136.
34. Schulman, H. (1995) Protein phosphorylation in neuronal plasticity and gene expression. Curr. Opin. Neurobiol., 5, 375-381.
35. Sotelo, C. and Alvarado-Mallart, R. M. (1987a) Embryonic and adult neurones interact to allow Purkinje cell replacement in mutant cerebellum. Nature, 327, 421-423.
36. Sotelo, C. and Alvarado-Mallart, R. M. (1987b) Reconstruction of the defective cerebellar circuitry in adult Purkinje cell degeneration mutant mice by Purkinje cell replacement through transplantation of solid embryonic implants. Neuroscience, 20, 1-22.
37. Sotelo, C. and Alvarado-Mallart, R. M. (1991) The reconstruction of cerebellar circuits. Trends Neurosci., 14, 350-355.
38. Sotelo, C. and Alvarado-Mallart, R. M. (1992) Cerebellar grafting as a tool to analyze new aspects of cerebellar development and plasticity. In Sotelo, C. and Llinás, R. (eds), The Cerebellum Revisited. Springer-Verlag, New York, pp. 84-115.
39. Steward, O. (1992) Signals that induce sprouting in the central nervous system: sprouting is delayed in mice exhibiting delayed axonal degeneration. Exp. Neurol., 118, 340-351.
40. Takahashi, M., Kovalchuk, Y. and Attwell, D. (1995) Pre- and postsynaptic determinants of EPSC waveform at cerebellar climbing fiber and parallel fiber to Purkinje cell synapses. J. Neurosci., 15, 5693-5702.
41. Tan, S. E., Wenthold, R. J. and Soderling, T. R. (1994) Phosphorylation of AMPA-type glutamate receptors by calcium/calmodulin-dependent protein kinase II and protein kinase C in cultured hippocampal neurons. J. Neurosci., 14, 1123-1129.
42. Tempia, F. and Konnerth, A. (1994) Calcium requirement of long-term depression and rebound potentiation in cerebellar Purkinje neurons. Semin. Cell Biol., 5, 243-250.
43. Tempia, F., Bravin, M. and Strata, P. (1995) Electrophysiological characteristics of excitatory synaptic currents of patch-clamped Purkinje neurons grafted on an adult cerebellum. Soc. Neurosci. Abstr., 20, 518.16.
44. Tempia, F., Kano, M., Schneggenburger, R., Schirra, C., Garaschuk, O., Plant, T. and Konnerth, A. (1996) The fractional calcium current through neuronal AMPA receptor channels with a 'low' calcium permeability. J. Neurosci., 16, 456-466.
45. Vincent, P., Armstrong, C. M. and Marty, A. (1992) Inhibitory synaptic currents in rat cerebellar Purkinje cell: modulation by postsynaptic depolarization. J. Physiol. (Lond.), 456, 453-471.
46. Wu, L. G. and Saggau, P. (1994) Presynaptic calcium is increased during normal synaptic transmission and paired-pulse facilitation, but not in long-term potentiation in area CA1 of hippocampus. J. Neurosci., 14, 645-654.
47. Zucker, R. S. (1989) Short-term synaptic plasticity. Annu. Rev. Neurosci., 12, 13-31.