The roles of protein phosphorylation/dephosphorylation in tumor necrosis factor antitumor effects

Journal of Interferon and Cytokine Research

Volumn 16, Issue 12, 1996, Pages 1021-1025

  Wang, Xin Yuan ^a,b   Kafka, Michael ^a   Dvilansky, Alexander ^a   Nathan, Ilana ^a  

^a BEN GURION UNIVERSITY OF THE NEGEV   (Israel)

^b CENTRAL SOUTH UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

TUMOR NECROSIS FACTOR;

ANIMAL CELL; ANTINEOPLASTIC ACTIVITY; ARTICLE; CELL STRAIN L 929; CONTROLLED STUDY; DEPHOSPHORYLATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION;

ANIMALIA;

EID: 0030452966     PISSN: 10799907     EISSN: None     Source Type: Journal    
DOI: 10.1089/jir.1996.16.1021     Document Type: Article

References (19)

1. BEUTLER, B., and CERAMI A. (1988). Tumor necrosis, cachexia, shock and inflammation: a common mediator. Annu. Rev. Biochem. 57, 505-518.
2. FIERS, W. (1991). Tumor necrosis factor. Characterization at the molecular, cellular and in vivo level. FEBS Lett. 285, 199-212.
3. VILCEK, J., and LEE, T.H. (1991). Tumor necrosis factor. New insights into the molecular mechanisms of its multiple actions. J. Biol. Chem. 266, 7313-7316.
4. HOHMANN, H.P., REMY, R., BROCKHAUS, M., and VAN LOON, A.P.G.M. (1989). Two different cell types have different major receptors for human tumor necrosis factor (TNFα). J. Biol. Chem. 264, 14927-14934.
5. SCHEURICH, P., UNGLAUB, R., MAXEINER, B., THOMA, B., ZUGMAIER, G., and PFIZENMAIER, K. (1986). Rapid modulation of tumor necrosis factor membrane receptors by activators of protein kinase C. Biochem. Biophys. Res. Commun. 141, 855-860.
6. SCHUTZE, S., SCHEURICH, P., PFIZENMAIER, K., and KRONKE, M. (1989). Tumor necrosis factor signal transduction. Tissue specific serine phosphorylation of a 25-kDa cytosolic protein. J. Biol. Chem. 264, 3562-3567.
7. KRONKE, M. SCHUTZE, S., SCHEURICH, P., and PFIZENMAIER, K. (1991). In Tumor Necrosis Factors: Structure. Function and Mechanism of Action. B. Aggarwal and J. Vilcek (eds.) New York: Marcel Dekker, pp. 189-216.
8. MATHIAS, S., YOUNES, A., KAN, C., ORLOW T. JOSEPH, C., and KOLESNICK, R. (1993). Activation of the sphingomyelin signaling pathway in intact EL4 cells and in a cell-free system by IL-1 beta. Science 259, 519-522.
9. EVANS, J.P.M., MIRE-SLUIS, A.R., HOFFBRAND, A.V., and WICKREMASINGHE, R.G. (1990). Binding of G-CSF, GM-CSF, tumor necrosis factor alpha, and gamma interferon to cell surface receptors on human myeloid leukemia cells triggers rapid tyrosine and serine phosphorylation of a 75-kD protein. Blood 75, 88-95.
10. KOHNO, M., NISHIZAWA, N., TSUJIMOTO, M., and NOMOTO, M. (1990). Mitogenic signaling pathway of tumor necrosis factor involves the rapid phosphorylation of 41,000-Mr and 43,000-Mr cytosol proteins. Biochem. J. 267, 91-98.
11. GUY, G.R., CHUA, S.P., WONG, N.S., NG, S.B., and TAN, Y.H. (1991). Interleukin 1 and tumor necrosis factor activate common multiple protein kinases in human fibroblasts. J. Biol. Chem. 267, 14343-14352.
12. AKIMARU, K., UTSUMI, T., SATO, E.F., KLOSTERGAARD, J., INOUE, M., and UTSUMI, K. (1992). Role of tyrosyl phosphorylation in neutrophil priming by tumor necrosis factor-alpha and granulocyte colony stimulating factor. Arch. Biochem. Biophys. 298, 703-709.
13. ERUSALIMSKY, J.D., FRIEDBERG, I., and ROZENGURT, E. (1988). Bombesin, diacylglycerols, and phorbol esters rapidly stimulate the phosphorylation of an Mr-80,000 protein kinase C substrate in permeabilized 3T3 cells. Effect of guanine nucleotides. J. Biol. Chem. 263, 19188-19194.
14. LAEMMLI, U.K. (1970). Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227, 680-685.
15. IMOTO, M., UMEZAWA, K., KOMURO, K., SAWA, T., TAKEUCHI, T., and UMEZAWA, H. (1987). Antitumor activity of erbstatin, a tyrosine protein kinase inhibitor. Jpn. J. Cancer Res. (Gann) 78, 329-332.
16. MISHRA, S., MATHUR, R., and HAMBURGER A.W. (1994). Modulation of the cytotoxic activity of tumor necrosis factor by protein tyrosine kinase and protein tyrosine phosphatase inhibitors. Lymphokine Cytokine Res. 13, 77-83.
17. O'NEILL, L.A., BIRD, T.A., and SAKLATVALA, J. (1990). How does interleukin 1 activate cell? Interleukin 1 signal transduction. Immunol. Today 11, 392-394.
18. IGARASHI, K., DAVID, M., FINBLOOM, D.S., and LARNER, A.C. (1993). In vitro activation of the transcription factor gamma interferon activation factor by gamma interferon: evidence for a tyrosine phosphatase/kinase signaling cascade. Mol. Cell. Biol. 13, 1634-1640.
19. KAFKA, M., DVILANSKY, A., and NATHAN, I. (1994). Rapid interferon-gamma-stimulated tyrosine phosphorylation of cytosolic and membranal proteins in HL-60 promyelocytic cells. Leuk. Res. 18, 205-211.