Frequencies, timing, and spatial patterns of co-suppression of nitrate reductase and nitrite reductase in transgenic tobacco plants

Plant Physiology

Volumn 112, Issue 4, 1996, Pages 1447-1456

  Palauqui, Jean Christophe ^a   Elmayan, Taline ^a   Dorlhac De Borne, François ^a,b   Crété, Patrice ^a   Charles, Chrystèle ^a   Vaucheret, Hervé ^a  

^a CEMAGREF   (France)

^b Institut du Tabac   (France)

Author keywords

[No Author keywords available]

Indexed keywords

NIA; NICOTIANA OBTUSIFOLIA; NICOTIANA TABACUM; TABACUM;

EID: 0030452646     PISSN: 00320889     EISSN: None     Source Type: Journal    
DOI: 10.1104/pp.112.4.1447     Document Type: Article

References (34)

1. Bevan M (1984) Binary Agrobacterium vectors for plant transformation. Nucleic Acids Res 12: 8711-8712
2. Boerjan W, Bauw G, Van Montagu M, Inze D (1994) Distinct phenotypes generated by overexpression and suppression of S-adenosyl-L-methionine synthetase reveal developmental patterns of gene silencing in tobacco. Plant Cell 6: 1401-1414
3. de Carvalho F, Gheysen G, Kushnir S, Van Montagu M, Inzé D, Castresana C (1992) Suppression of beta-1,3-glucanase transgene expression in homozygous plants. EMBO J 11: 2595-2602
4. de Carvalho-Niebel F, Frendo P, Van Montagu M, Cornelissen M (1995) Post-transcriptional co-suppression of beta-1,3-glucanase genes does not affect accumulation of transgene nuclear mRNA. Plant Cell 7: 347-358
5. Dehio C, Schell J (1994) Identification of plant genetic loci involved in a posttranscriptional mechanism for meiotically reversible transgene silencing. Proc Natl Acad Sci USA 91: 5538-5542
6. Dorlhac de Borne F, Vincentz M, Chupeau Y, Vaucheret H (1994) Co-suppression of nitrate reductase host genes and transgenes in transgenic tobacco plants. Mol Gen Genet 243: 613-621
7. Dougherty WG, Parks TD (1995) Transgenes and gene suppression: telling us something new? Current Opinion in Cell Biology 7: 399-405
8. Elmayart T, Vaucheret H (1995) Expression of single copies of a strongly-expressed 35S-transgene can be silenced post-transcriptionally. Plant J 9: 787-797
9. Faure J-D, Vincentz M, Kronenberger J, Caboche M (1991) Co-regulated expression of nitrate and nitrite reductases. Plant J 1: 107-113
10. Flavell RB (1994) Inactivation of gene expression in plants as a consequence of specific sequence duplication. Proc Natl Acad Sci USA 91: 3490-3496
11. Gabard J, Marion-Poll A, Chérel I, Meyer C, Müller AJ, Caboche M (1987) Isolation and characterization of Nicotiana plumbaginifolia nitrate reductase-deficient mutants: genetic and biochemical analysis of the NIA complementation group. Mol Gen Genet 209: 596-606
12. Gritz L, Davies J (1983) Plasmid-encoded hygromycin B resistance: the sequence of hygromycin B phosphotransferase gene and its expression in Escherichia coli and Saccharomyces cerevisiae. Gene 25: 179-188
13. Hart CM, Fisher B, Neuhaus J-M, Meins F (1992) Regulated inactivation of homologous gene expression in transgenic Nicotiana sylvestris plants containing a defense-related tobacco chitinase gene. Mol Gen Genet 235: 179-188
14. Ingelbrecht I, Van Houdt H, Van Montagu M, Depicker A (1994) Posttranscriptional silencing of reporter transgenes in tobacco correlates with DNA methylation. Proc Natl Acad Sci USA 91: 10502-10506
15. Jorgensen R (1990) Altered gene expression in plants due to trans interactions between homologous genes. Trends Biotechnol 8: 340-344
16. Kronenberger J, Lépingle A, Caboche M, Vaucheret H (1993) Cloning and expression of distinct nitrite reductases in tobacco leaves and roots. Mol Gen Genet 236: 203-208
17. Linn F, Heidmann I, Saedler H, Meyer P (1990) Epigenetic changes in the expression of the maize A1 gene in Petunia hybrida: role of the numbers of integrated gene copies and state of methylation. Mol Gen Genet 222: 329-336
18. Matzke MA, Matzke AJM (1995) How and why do plants inactivate homologous (trans)genes? Plant Physiol 107: 679-685
19. Matzke MA, Neuhuber F, Matzke AJM (1993) A variety of epistatic interactions can occur between partially homologous transgene loci brought together by sexual crossing. Mol Gen Genet 236: 379-386
20. Matzke MA, Primig M, Trnovsky J, Matzke AJM (1989) Reversible methylation and inactivation of marker genes in sequentially transformed tobacco plants. EMBO J 8: 643-649
21. Meins F Jr (1989) A biochemical switch model for cell-heritable variation in cytokinin requirement. In R Goldberg, ed, Molecular Basis of Plant Development. Liss, New York, pp 13-24
22. Meins F Jr, Kunz C (1994) Gene silencing in transgenic plants: a heuristic autoregulation model. In P Meyer, ed, Current Topics in Microbiology and Immunology. Springer-Verlag, Berlin, pp 105-120
23. Meyer P, Heidmann I, Niedenhof I (1993) Differences in DNA-methylation are associated with a paramutation phenomenon in transgenic petunia. Plant J 4: 89-100
24. Palauqui J-C, Vaucheret H (1995) Field trial analysis of nitrate reductase co-suppression: a comparative study of 38 combinations of transgene loci. Plant Mol Biol 29: 149-159
25. Park Y-D, Papp I, Moscone EA, Iglesias VA, Vaucheret H, Matzke MA, Matzke AJM (1996) Gene silencing mediated by promoter homology occurs at the level of transcription and results in meiotically heritable alterations in methylation and gene activity. Plant J 9: 183-194
26. Phillips RL, Matzke MA, Oono K (1995) Treasure your exceptions. Plant Cell 10: 1522-1527
27. Saux C, Lemoine Y, Marion-Poll A, Valadier MH, Deng M, Morot-Gaudry J-F (1987) Consequence of absence of nitrate reductase activity on photosynthesis in Nicotiana plumbaginifolia plants. Plant Physiol 84: 67-72
28. Van Blokland R, Vandergeest N, Mol JNM, Kooter JM (1994) Transgene-mediated suppression of chalcone synthase expression in Petunia hybrida results from an increase in RNA turnover. Plant J 6: 861-877
29. Van der Krol AR, Mur LA, Beld M, Mol JNM, Stuitje AR (1990) Flavonoid genes in petunia: addition of a limited number of gene copies may lead to a suppression of gene expression. Plant Cell 2: 291-299
30. Vaucheret H (1993) Identification of a general silencer for 19S and 35S promoters in a transgenic tobacco plant: 90 pb of homology in the promoter sequences are sufficient for trans-inactivation. C R Acad Sci Paris 316: 1471-1483
31. Vaucheret H, Kronenberger J, Lepingle A, Vilaine F, Boulin J-P, Caboche M (1992) Inhibition of tobacco nitrite reductase activity by expression of antisense RNA. Plant J 2: 559-569
32. Vaucheret H, Palauqui J-C, Elmayan T, Moffatt B (1995) Molecular and genetic analysis of nitrite reductase co-suppression in transgenic tobacco plants. Mol Gen Genet 248: 311-317
33. Vincentz M, Caboche M (1991) Constitutive expression of nitrate reductase allows normal growth and development of Nicotiana plumbaginifolia plants. EMBO J 10: 1027-1035
34. Vincentz M, Moureaux T, Leydecker M-T, Vaucheret H, Caboche M (1993) Regulation of nitrate and nitrite reductase expression in Nicotiana plumbaginifolia leaves by nitrogen and carbon metabolites. Plant J 3: 315-324