메뉴 건너뛰기




Volumn 16, Issue 3, 1996, Pages 149-167

Effects of the antiepileptic drug valproic acid on the development of the axolotl (ambystoma mexicanum): Histological investigations

Author keywords

Cell adhesion; Cytoskeleton; Embryotoxicity; Extracellular matrix; In vitro test; Neural tube defects

Indexed keywords

ANTICONVULSIVE AGENT; VALPROIC ACID;

EID: 0030452630     PISSN: 02703211     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1520-6866(1996)16:3<149::AID-TCM2>3.0.CO;2-I     Document Type: Article
Times cited : (4)

References (64)
  • 1
    • 73649173245 scopus 로고
    • Propriétés pharmacodynamic de l'ácide n-depropylacétique. ler memoire: Propriétés antiépileptiques
    • Meunier H, Carraz G, Meunier Y, Eymard P, Aimard M: Propriétés pharmacodynamic de l'ácide n-depropylacétique. ler memoire: propriétés antiépileptiques. Therapie 18:435-438, 1963.
    • (1963) Therapie , vol.18 , pp. 435-438
    • Meunier, H.1    Carraz, G.2    Meunier, Y.3    Eymard, P.4    Aimard, M.5
  • 2
    • 0017349288 scopus 로고
    • Sodium valproate: A review of its pharmacological properties and therapeutic efficacy in epilepsy
    • Pinder RM, Brogden RN, Speight TM, Avery GS: Sodium valproate: A review of its pharmacological properties and therapeutic efficacy in epilepsy. Drugs 13:81-123, 1977.
    • (1977) Drugs , vol.13 , pp. 81-123
    • Pinder, R.M.1    Brogden, R.N.2    Speight, T.M.3    Avery, G.S.4
  • 3
    • 0022243946 scopus 로고
    • Valproate: An update review
    • Gram L, Bentsen K: Valproate: An update review. Acta Neurol Scand 72:129-139, 1985.
    • (1985) Acta Neurol Scand , vol.72 , pp. 129-139
    • Gram, L.1    Bentsen, K.2
  • 4
    • 0018668256 scopus 로고
    • A direct hepatotoxic effect of valproic acid
    • Sussmann NM, McLain LW: A direct hepatotoxic effect of valproic acid. JAMA 242:1173-1175, 1979.
    • (1979) JAMA , vol.242 , pp. 1173-1175
    • Sussmann, N.M.1    McLain, L.W.2
  • 6
    • 0019965961 scopus 로고
    • Maternal valproic acid and congenital neural tube defects
    • Robert E, Guibaud P: Maternal valproic acid and congenital neural tube defects. Lancet 2:937, 1982.
    • (1982) Lancet , vol.2 , pp. 937
    • Robert, E.1    Guibaud, P.2
  • 7
    • 0021069855 scopus 로고
    • Valproate and birth defects
    • Robert E, Rosa F: Valproate and birth defects. Lancet 2:1142, 1983.
    • (1983) Lancet , vol.2 , pp. 1142
    • Robert, E.1    Rosa, F.2
  • 8
    • 0021636834 scopus 로고
    • Spina bifida and in-utero exposure to valproate
    • Lindhout D, Meinhardi H: Spina bifida and in-utero exposure to valproate. Lancet 2:396, 1984.
    • (1984) Lancet , vol.2 , pp. 396
    • Lindhout, D.1    Meinhardi, H.2
  • 10
    • 0022571613 scopus 로고
    • Utero exposure to valproate and neural tube defects
    • Lindhout D, Schmidt D: In utero exposure to valproate and neural tube defects. Lancet 1:1392-1393, 1986.
    • (1986) Lancet , vol.1 , pp. 1392-1393
    • Lindhout, D.1    Schmidt, D.2
  • 14
    • 0023946794 scopus 로고
    • Pharmakokinetische Grundlagen der Teratogenität von Arzneimitteln
    • Nau H: Pharmakokinetische Grundlagen der Teratogenität von Arzneimitteln. Internist 29:179-192, 1988.
    • (1988) Internist , vol.29 , pp. 179-192
    • Nau, H.1
  • 15
    • 0021638232 scopus 로고
    • Valproic acid and metabolites: Pharmacological and toxicological studies
    • Nau H, Löscher W: Valproic acid and metabolites: Pharmacological and toxicological studies. Epilepsia 25(Suppl I):S14-S22, 1984.
    • (1984) Epilepsia , vol.25 , Issue.1 SUPPL.
    • Nau, H.1    Löscher, W.2
  • 16
    • 0024990748 scopus 로고
    • Effects of valproic acid, some of its metabolites and analogues on prenatal development of rats in vitro and comparison with effects in vivo
    • Klug S, Lewandowski C, Zappel F, Merker HJ, Nau H, Neubert D: Effects of valproic acid, some of its metabolites and analogues on prenatal development of rats in vitro and comparison with effects in vivo. Arch Toxicol 64:545-553, 1990.
    • (1990) Arch Toxicol , vol.64 , pp. 545-553
    • Klug, S.1    Lewandowski, C.2    Zappel, F.3    Merker, H.J.4    Nau, H.5    Neubert, D.6
  • 17
    • 0026556607 scopus 로고
    • Valproic acid induced spina bifida: A mouse model
    • Ehlers K, Stürje H, Merker HJ, Nau H: Valproic acid induced spina bifida: A mouse model. Teratology 45:145-154, 1992.
    • (1992) Teratology , vol.45 , pp. 145-154
    • Ehlers, K.1    Stürje, H.2    Merker, H.J.3    Nau, H.4
  • 19
    • 0020661447 scopus 로고
    • Teratogenic effects of valproic acid and diphenylhydantoin on mouse embryo in culture
    • Bruckner A, Lee YL, O'Shea KS, Henneberry RC: Teratogenic effects of valproic acid and diphenylhydantoin on mouse embryo in culture. Teratology 27:29-42, 1983.
    • (1983) Teratology , vol.27 , pp. 29-42
    • Bruckner, A.1    Lee, Y.L.2    O'Shea, K.S.3    Henneberry, R.C.4
  • 20
    • 84995036658 scopus 로고
    • Embryotoxic effects of valproic acid (VPA), 4-en VPA and 2-en VPA: Comparative studies with species of various levels of organization
    • Kirschbaum F, Oberemm A: Embryotoxic effects of valproic acid (VPA), 4-en VPA and 2-en VPA: Comparative studies with species of various levels of organization. Naunyn Schmiedeberg's Arch Pharmacol (Suppl) 344:A46, 1991.
    • (1991) Naunyn Schmiedeberg's Arch Pharmacol (Suppl) , vol.344
    • Kirschbaum, F.1    Oberemm, A.2
  • 21
    • 25044461310 scopus 로고
    • Amphibians as alternative experimental models? Abnormal development of the central nervous system (CNS) induced by valproic acid
    • Oberemm A, Kirschbaum F: Amphibians as alternative experimental models? Abnormal development of the central nervous system (CNS) induced by valproic acid. Naunyn Schmiedeberg's Arch Pharmacol (Suppl) 343:A468, 1991.
    • (1991) Naunyn Schmiedeberg's Arch Pharmacol (Suppl) , vol.343
    • Oberemm, A.1    Kirschbaum, F.2
  • 22
    • 84995057495 scopus 로고
    • Valproic acid induced abnormal development of the central nervous system (CNS) of the axolotl: Stage-dependent effects
    • Oberemm A, Kirschbaum F: Valproic acid induced abnormal development of the central nervous system (CNS) of the axolotl: stage-dependent effects. Naunyn Schmiedeberg's Arch Pharmacol (Suppl) 344:A47, 1991.
    • (1991) Naunyn Schmiedeberg's Arch Pharmacol (Suppl) , vol.344
    • Oberemm, A.1    Kirschbaum, F.2
  • 23
    • 0026994501 scopus 로고
    • Valproic acid induced abnormal development of the central nervous system of three species of amphibians: Implications for neural tube defects and alternative experimental systems
    • Oberemm A, Kirschbaum F: Valproic acid induced abnormal development of the central nervous system of three species of amphibians: Implications for neural tube defects and alternative experimental systems. Teratogenesis Carcinog Mutagen 12:251-262, 1992.
    • (1992) Teratogenesis Carcinog Mutagen , vol.12 , pp. 251-262
    • Oberemm, A.1    Kirschbaum, F.2
  • 26
    • 0014776772 scopus 로고
    • Neurulation in Xenopus laevis. An analysis and model based upon light and electron microscopy
    • Schroeder TE: Neurulation in Xenopus laevis. An analysis and model based upon light and electron microscopy. J Embryol Exp Morphol 23:427-462, 1970.
    • (1970) J Embryol Exp Morphol , vol.23 , pp. 427-462
    • Schroeder, T.E.1
  • 27
    • 0016164151 scopus 로고
    • The mechanisms of neural tube formation
    • Karfunkel P: The mechanisms of neural tube formation. Int Rev Cytol 38:245-271, 1974.
    • (1974) Int Rev Cytol , vol.38 , pp. 245-271
    • Karfunkel, P.1
  • 28
    • 0020330009 scopus 로고
    • On the morphogenesis of the early rudiments of the developing central nervous system
    • Schoenwolf GC: On the morphogenesis of the early rudiments of the developing central nervous system. Scanning Electron Microsc I:289-308, 1982.
    • (1982) Scanning Electron Microsc , vol.1 , pp. 289-308
    • Schoenwolf, G.C.1
  • 29
    • 0022339117 scopus 로고
    • A review of the theories of vertebrate neurulation and their relationship to mechanics of neural tube birth defects
    • Gordon R: A review of the theories of vertebrate neurulation and their relationship to mechanics of neural tube birth defects. J Embryol Exp Morphol 89(Suppl):229-255, 1985.
    • (1985) J Embryol Exp Morphol , vol.89 , Issue.SUPPL. , pp. 229-255
    • Gordon, R.1
  • 30
    • 0023760079 scopus 로고
    • Origin of the dorsal surface of the neural tube by progressive delamination of the epidermal ectoderm and neuroepithelium: Implications for neurulation and neural tube defects
    • Martins-Green M: Origin of the dorsal surface of the neural tube by progressive delamination of the epidermal ectoderm and neuroepithelium: Implications for neurulation and neural tube defects. Development 103:687-706, 1988.
    • (1988) Development , vol.103 , pp. 687-706
    • Martins-Green, M.1
  • 31
    • 0025364510 scopus 로고
    • Mechanisms of neurulation: Traditional viewpoints and recent advances
    • Schoenwolf GC, Smith JL: Mechanisms of neurulation: Traditional viewpoints and recent advances. Development 109:243-270, 1990.
    • (1990) Development , vol.109 , pp. 243-270
    • Schoenwolf, G.C.1    Smith, J.L.2
  • 33
    • 0015063133 scopus 로고
    • The role of microtubule and microfilaments in neurulation in Xenopus
    • Karfunkel P: The role of microtubule and microfilaments in neurulation in Xenopus. Dev Biol 25:30-56, 1971.
    • (1971) Dev Biol , vol.25 , pp. 30-56
    • Karfunkel, P.1
  • 34
    • 0000195239 scopus 로고
    • Microtubules and microfilaments in amphibian neurulation
    • Burnside B: Microtubules and microfilaments in amphibian neurulation. Am Zool 13:939-1006, 1973.
    • (1973) Am Zool , vol.13 , pp. 939-1006
    • Burnside, B.1
  • 35
    • 0006040719 scopus 로고
    • Effects of vinblastine sulphate, colchicine, and guanosine phosphate on cell morphogenesis during amphibian neurulation
    • Löfberg J, Jacobson CO: Effects of vinblastine sulphate, colchicine, and guanosine phosphate on cell morphogenesis during amphibian neurulation. Zoon 2:85-98, 1974.
    • (1974) Zoon , vol.2 , pp. 85-98
    • Löfberg, J.1    Jacobson, C.O.2
  • 36
    • 0015155261 scopus 로고
    • Microtubules and microfilaments in newt neurulation
    • Burnside B: Microtubules and microfilaments in newt neurulation. Dev Biol 26:416-441, 1971.
    • (1971) Dev Biol , vol.26 , pp. 416-441
    • Burnside, B.1
  • 37
    • 0015066825 scopus 로고
    • Cell shape and morphology of the neural tube: Implications for microtubule function
    • Handel MA, Roth LE: Cell shape and morphology of the neural tube: Implications for microtubule function. Dev Biol 25:78-95, 1971.
    • (1971) Dev Biol , vol.25 , pp. 78-95
    • Handel, M.A.1    Roth, L.E.2
  • 38
    • 0015400149 scopus 로고
    • The activity of microtubules and microfilaments in neurulation in the chick
    • Karfunkel P: The activity of microtubules and microfilaments in neurulation in the chick. J Exp Zool 181:289-302, 1972.
    • (1972) J Exp Zool , vol.181 , pp. 289-302
    • Karfunkel, P.1
  • 39
    • 0014502585 scopus 로고
    • Effects of β-mercaptoethanol on the fine structure of the neural plate of the chick embryo
    • Messier PE: Effects of β-mercaptoethanol on the fine structure of the neural plate of the chick embryo. J Embryol Exp Morphol 21:309-329, 1969.
    • (1969) J Embryol Exp Morphol , vol.21 , pp. 309-329
    • Messier, P.E.1
  • 41
    • 0018828554 scopus 로고
    • Ultrastructure of secondary neurulation in chick embryo
    • Schoenwolf GC, DeLongo J: Ultrastructure of secondary neurulation in chick embryo. Am J Anat 158:43-63, 1980.
    • (1980) Am J Anat , vol.158 , pp. 43-63
    • Schoenwolf, G.C.1    DeLongo, J.2
  • 42
    • 0023191054 scopus 로고
    • Shaping of the chick neuroepithelium during primary and secondary neurulation: Role of cell elongation
    • Schoenwolf GC, Powers ML: Shaping of the chick neuroepithelium during primary and secondary neurulation: Role of cell elongation. Anat Rec 218:182-195, 1987.
    • (1987) Anat Rec , vol.218 , pp. 182-195
    • Schoenwolf, G.C.1    Powers, M.L.2
  • 43
    • 0006108558 scopus 로고
    • Colchicine teratogenesis in hamster embryos
    • Ferm VH: Colchicine teratogenesis in hamster embryos. Proc Soc Exp Biol Med 112:775-778, 1963.
    • (1963) Proc Soc Exp Biol Med , vol.112 , pp. 775-778
    • Ferm, V.H.1
  • 44
    • 3142552974 scopus 로고
    • The cytoskeleton in neurulation: Role of cations
    • Harrison RJ: Cambridge: Cambridge University Press
    • O'Shea S: The cytoskeleton in neurulation: Role of cations. In Harrison RJ: "Progress in Anatomy, Vol. 1." Cambridge: Cambridge University Press, 1981, pp 36-60.
    • (1981) Progress in Anatomy , vol.1 , pp. 36-60
    • O'Shea, S.1
  • 45
    • 0013895121 scopus 로고
    • The fine structure of the embryonic mouse neural tube with special reference to cytoplasmic microtubules
    • Herman L, Kaufman SL: The fine structure of the embryonic mouse neural tube with special reference to cytoplasmic microtubules Dev Biol 13:145-162, 1966.
    • (1966) Dev Biol , vol.13 , pp. 145-162
    • Herman, L.1    Kaufman, S.L.2
  • 46
    • 0021240226 scopus 로고
    • Histological and ultrastructural studies of secondary neurulation in mouse embryos
    • Schoenwolf GC: Histological and ultrastructural studies of secondary neurulation in mouse embryos. Am J Anat 169:361-376, 1984.
    • (1984) Am J Anat , vol.169 , pp. 361-376
    • Schoenwolf, G.C.1
  • 47
    • 84982342045 scopus 로고
    • Cell number and cell size in the ectoderm during neurulation (Amblystoma maculatum)
    • Gillette R: Cell number and cell size in the ectoderm during neurulation (Amblystoma maculatum). J Exp Zool 96:201-222, 1944.
    • (1944) J Exp Zool , vol.96 , pp. 201-222
    • Gillette, R.1
  • 48
    • 0343174185 scopus 로고
    • Cell migration in the neural plate and the process of neurulation in the axolotl larva
    • Jacobson CO: Cell migration in the neural plate and the process of neurulation in the axolotl larva. Zool Bidr Uppsala 35:433-449, 1962.
    • (1962) Zool Bidr Uppsala , vol.35 , pp. 433-449
    • Jacobson, C.O.1
  • 49
    • 0014375344 scopus 로고
    • Analysis of morphogenetic movements in the neural plate of the newt Taricha torosa
    • Burnside MB, Jacobson AG: Analysis of morphogenetic movements in the neural plate of the newt Taricha torosa. Dev Biol 18:537-552, 1968.
    • (1968) Dev Biol , vol.18 , pp. 537-552
    • Burnside, M.B.1    Jacobson, A.G.2
  • 50
    • 0016991649 scopus 로고
    • Changes in the shape of the developing vertebrate nervous system analyzed experimentally, mathematically and by computer simulation
    • Jacobson AG, Gordon R: Changes in the shape of the developing vertebrate nervous system analyzed experimentally, mathematically and by computer simulation. J Exp Zool 197:191-246, 1976.
    • (1976) J Exp Zool , vol.197 , pp. 191-246
    • Jacobson, A.G.1    Gordon, R.2
  • 51
    • 0020581958 scopus 로고
    • Neural crest cell migration: Requirements for exogenous fibronectin and high cell density
    • Rovasio RA, Delouvee A, Yamada KM, Timpl R, Thiery JP: Neural crest cell migration: Requirements for exogenous fibronectin and high cell density. J Cell Biol 96:462-473, 1983.
    • (1983) J Cell Biol , vol.96 , pp. 462-473
    • Rovasio, R.A.1    Delouvee, A.2    Yamada, K.M.3    Timpl, R.4    Thiery, J.P.5
  • 52
    • 0016782826 scopus 로고
    • Migration of cranial neural crest cells in a cell-free hyaluronrich matrix
    • Pratt RM, Larsen MA, Jahnston MC: Migration of cranial neural crest cells in a cell-free hyaluronrich matrix. Dev Biol 44:298-305, 1975.
    • (1975) Dev Biol , vol.44 , pp. 298-305
    • Pratt, R.M.1    Larsen, M.A.2    Jahnston, M.C.3
  • 53
    • 0018179949 scopus 로고
    • Analysis of glycosaminoglycans within the extracellular environments encountered by migrating neural crest cells
    • Derby MA: Analysis of glycosaminoglycans within the extracellular environments encountered by migrating neural crest cells. Dev Biol 66:321-336, 1978.
    • (1978) Dev Biol , vol.66 , pp. 321-336
    • Derby, M.A.1
  • 54
    • 0017694766 scopus 로고
    • Glycosaminoglycans and glycoprotein synthesis by cranial neural crest cells in vitro
    • Greenberg JH, Pratt RM: Glycosaminoglycans and glycoprotein synthesis by cranial neural crest cells in vitro. Cell Differ 66:119-132, 1977.
    • (1977) Cell Differ , vol.66 , pp. 119-132
    • Greenberg, J.H.1    Pratt, R.M.2
  • 55
    • 0018066673 scopus 로고
    • Distribution and synthesis of glycosaminoglycans during quail neural crest morphogenesis
    • Pintar JE: Distribution and synthesis of glycosaminoglycans during quail neural crest morphogenesis. Dev Biol 67:444-464, 1978.
    • (1978) Dev Biol , vol.67 , pp. 444-464
    • Pintar, J.E.1
  • 56
    • 0018150503 scopus 로고
    • The early migration of neural crest cells in the trunk region of the avian embryo: An electron microscopic study
    • Tosney KW: The early migration of neural crest cells in the trunk region of the avian embryo: An electron microscopic study. Dev Biol 62:317-333, 1978.
    • (1978) Dev Biol , vol.62 , pp. 317-333
    • Tosney, K.W.1
  • 57
    • 0023070055 scopus 로고
    • Valproic acid teratogenesis and embryonic lipid metabolism
    • Clarke DO, Brown NA: Valproic acid teratogenesis and embryonic lipid metabolism. Arch Toxicol Suppl 11:143-147, 1987.
    • (1987) Arch Toxicol Suppl , vol.11 , pp. 143-147
    • Clarke, D.O.1    Brown, N.A.2
  • 58
    • 84982339248 scopus 로고
    • A study of the mechanics of gastrulation. Part II
    • Holtfreter J: A study of the mechanics of gastrulation. Part II. J Exp Zool 95:171-212, 1944.
    • (1944) J Exp Zool , vol.95 , pp. 171-212
    • Holtfreter, J.1
  • 59
    • 0017754952 scopus 로고
    • An SEM study of cellular morphology, contact, and arrangement, as related to gastrulation in Xenopus laevis
    • Keller RE, Schoenwolf GC: An SEM study of cellular morphology, contact, and arrangement, as related to gastrulation in Xenopus laevis. Wilhelm Roux Arch 182:165-186, 1977.
    • (1977) Wilhelm Roux Arch , vol.182 , pp. 165-186
    • Keller, R.E.1    Schoenwolf, G.C.2
  • 60
    • 0018188042 scopus 로고
    • Time-lapse cinemicrographic analysis of superficial cell behavior and prior to gastruiation in Xenopus laevis
    • Keller RE: Time-lapse cinemicrographic analysis of superficial cell behavior and prior to gastruiation in Xenopus laevis. J Morphol 157:223-248, 1978.
    • (1978) J Morphol , vol.157 , pp. 223-248
    • Keller, R.E.1
  • 62
    • 0027357131 scopus 로고
    • Mesodermal cell adhesion to fibronectin-rich fibrillar extra-cellular matrix is required for normal Rana pipiens gastrulation
    • Johnson KE, Darribère T, Boucaut JC: Mesodermal cell adhesion to fibronectin-rich fibrillar extra-cellular matrix is required for normal Rana pipiens gastrulation. J Exp Zool 265:40-53, 1993.
    • (1993) J Exp Zool , vol.265 , pp. 40-53
    • Johnson, K.E.1    Darribère, T.2    Boucaut, J.C.3
  • 63
    • 0023711018 scopus 로고
    • Glutathione status and the incidence of neural tube defects elicited by direct acting teratogens in vitro
    • Harris C, Stark KL, Juchau MR: Glutathione status and the incidence of neural tube defects elicited by direct acting teratogens in vitro. Teratology 37:577-590, 1988.
    • (1988) Teratology , vol.37 , pp. 577-590
    • Harris, C.1    Stark, K.L.2    Juchau, M.R.3
  • 64
    • 0025355724 scopus 로고
    • Teratogenic effects on the neuroepithelium of the CD-1 mouse embryo exposed in utero to sodium valproate
    • Turner S, Sucheston ME, de Philip RM, Paulson RB: Teratogenic effects on the neuroepithelium of the CD-1 mouse embryo exposed in utero to sodium valproate. Teratology 41:421-442, 1990.
    • (1990) Teratology , vol.41 , pp. 421-442
    • Turner, S.1    Sucheston, M.E.2    De Philip, R.M.3    Paulson, R.B.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.