Serum zinc, copper, magnesium, proteins and superoxide dismutase in leprosy patients on multidrug therapy a follow-up study

Indian Journal of Leprosy

Volumn 68, Issue 4, 1996, Pages 325-333

  Sethi, N C ^a,b   Madadi, A J ^a   Bhandari, S ^a  

^a MGM MEDICAL COLLEGE   (India)

^b Manik Bhavan   (India)

Author keywords

[No Author keywords available]

Indexed keywords

COPPER; LEPROSTATIC AGENT; MAGNESIUM; PROTEIN; SUPEROXIDE DISMUTASE; ZINC;

ARTICLE; CONTROLLED STUDY; HUMAN; LEPROSY; MAJOR CLINICAL STUDY;

BLOOD PROTEINS; COPPER; HUMANS; LEPROSTATIC AGENTS; LEPROSY; MAGNESIUM; SUPEROXIDES; ZINC;

EID: 0030452605     PISSN: 02549395     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (45)

1. Ajaishankar, Gupta SB, Sharma JN 1976. A study of serum and skin zinc in leprosy. Indian J Dermatol Venereol Leprol 42:268.
2. Atkins E, Bodel P, Fever ZBW et al 1974. The inflammatory process. Edn 2, Academic Press, New York, pp 467-514.
3. Babior BM, Kipnes RS, Curnnatte JT 1973. Biological defence mechanisms. The production by leukocytes of Superoxide. A potential bactericidal agent. J Clin Invest 52:741-744.
4. Beisel WR, Pekarek RS 1972. Acute stress and trace element metabolism. Rev Neurobiol (Suppl) 1:53-82.
5. Bjorksten B, Back O, Gustavson KH et al 1980. Zinc and immune function in Down's Syndrome. Acta Paediatr Scand 69:183-197.
6. Brendstrup P 1953. Serum iron total iron binding capacity of serum copper in acute hepatitis. Acta Med Scand 146:107.
7. Cartwright GE, Wintrobe MM 1964. The question of copper deficiency in man. Am J Clin Nutr 15:94.
8. Chitre VS, Balasubramanyam M 1969. Changes in serum copper and PPD oxidase in different diseases. Differential observations in certain types of leprosy and kwashiorkor. Indian J Med Res 57:228.
9. Chvapil M 1976. Effect of zinc on cells and biomembranes. Med Clin North America 60:799-812.
10. Dhople AM, Magar NG 1962. Studies in blood chemistry of leprosy. Lepr India 34:299-305.
11. Fridovich I 1974. Advances in enzymology 4:35-97, cited by Kakkar 1985.
12. Fridovich I 1978. The biology of oxygen radicals. Science 201:875-880.
13. Golden MHN, Jackson AA, Golden BE 1977. Effect of zinc on thymus of recently malnourished children. Lancet 2:1057-1059.
14. Gupta SC, Mehrotra TN, Kapoor KK, Indrayan A 1971. A study of serum copper and PPD oxidase in different types of leprosy. Indian J Path Bact:174-179.
15. Kakkar P 1985. Biomedical and environmental implications of Superoxide dismutase. Life Scie Adv 4 (1C):24.
16. Koch HJ, Smith ER, McNeely J 1957. Analysis of trace elements in human tissue II. The lymphomatous diseases. Cancer 10:151.
17. Lahey ME, Gubler CJ, Cartwright GE, Wintrobe MM 1953. Studies in copper metabolism. Blood copper in normal human subjects. J Clin Invest 32:322.
18. Leopold IH 1978. Zinc deficiency and visual impairment. Amer J Ophthalmol 85:871-875.
19. Lundin, Rose 1958. Cited by Ramu G & Nagarajan V 1962.
20. Manander HK, Huber W 1977. Ozotein, the drug version of bovine Cu-Zn Superoxide dismutase II. A summary account of clinical trial in man and animals. Superoxide and Superoxide dismutase. eds AM Michelson, JM McCord, I Fridovich, Edn 1, Academic press, New York, pp 537.
21. Markovitz H, Gubler CJ, Mahoney JP et al 1955. Studies on copper metabolism XIV. Copper ceruloplasmin and oxidase activity in sera of normal human subjects, pregnant women, patients with infection, hepatolenticular degeneration and nephrotic syndrome. J Clin Invest 34:1498.
22. Marklund S, Marklund G 1974. Involvement of Superoxide anion radical in the auto-oxidation of pyrogallol and a convenient assay for Superoxide dismutase. Eur J Biochem 47:469.
23. Mathur NK, Sharma M, Mangal HN, Rai SM 1984. Serum zinc levels in subtypes of leprosy. Int J Lepr 52:327-330.
24. McCord JM, Kelly B Bjr, Fridovich I 1971. An enzyme based theory of obligate anerobiosis. The physiological function of Superoxide dismutase. Proc Natl Acad Sci USA 68:1024-1027.
25. Mennen U, Howells C, Wiese AJ 1993. Serum zinc, sodium, calcium, magnesium and potassium levels and standard diet in leprosy patients. Indian J Lepr 65:415-421.
26. Nigam P, Dayal SG, Shrivastava P, Joshi LD 1979. Serum calcium and magnesium in leprosy. Asian J Infec Dis 3:81-83.
27. Nigam P, Mukhija RD, Agrawal AK et al 1985. Serum cations (calcium and magnesium) in leprosy. Indian J Lepr 57:529-533.
28. Oleske JM, Westphal ML, Shores S et al 1979. Zinc therapy of depressed cellular immunity in acrodermatitis enteropathica. Am J Dis Child 133:915-918.
29. Onn BB, Khong KY, Greaves MW, Plummer VW 1974. Trophic skin ulceration of leprosy: skin and serum zinc concentrations. Brit Med Jour 2:531-533.
30. Pekarek RS, Beisel WR 1972. Redistribution and sequestering of essential trace elements during acute infection. Nutr Proc Int Congs IX 1972:183-185.
31. Pekarek RS, Sandstead HH, Jacob RA, Barcome DF 1979. Abnormal cellular immune responses during acquired zinc deficiency. Am J Clin Nutr 32:1466-1471.
32. Powanda MC 1977. Changes in the body balance of nitrogen and other key nutritional description and underlying mechanisms. Am J Clin Nutr 30:1254-1268.
33. Prasad AS 1976. Deficiency of zinc in man and its toxicity. Trace elements in human health and disease, ed AS Prasad, D Oberleas, Academic press, New York, pp 1-17.
34. Ramanathan MK 1960. Raised level of serum copper in leprosy with and without gynaecomastia, Bull Soc Path Exot 53:608.
35. Ramanathan MK, Santhanagopalan T, Balasubramanyam M 1963. Some serum enzymes in lepromatous leprosy. Indian J Path Bact 3:123.
36. Ramu G, Nagarajan V 1961. Biochemical investigations in reactive states in leprosy. Lancet 11:89.
37. Ramu G, Nagarajan V 1962. Biochemical investigations in leprosy. J Indian Med Assoc 30(g):449-469.
38. Rao KN, Gupta JD, Sehgal VN et al 1985. Trace elements in sera of leprosy spectrum. Indian J Lepr 57:556-561.
39. Rundles C, Rundles C, Iwata T et al 1981. Zinc deficiency depressed thymic harmone and T-lymphocytes dysfunction in patients with hypoglobulinemia. Clin Immunol Immunopathol 21:387-396.
40. Sher R, Shulman G, Bailey P, Politzer WM 1981. Serum trace elements and vitamin A in leprosy sub types. Am J Clin Nutr 34:1918-1924.
41. Sheshkin J, Zeimer R 1977. In vivo study of trace elements in leprous skin. Int J Dermatol 16:745-747.
42. Sinha SN, Gupta SC, Bhista D 1978. Serum calcium and magnesium in different types of leprosy. Lepr India 50:54-58.
43. Venkatesan K, Kannan KB, Bharadwaj VP 1983. Serum copper and zinc in leprosy and effect of oral zinc therapy. Indian J Med Res 78:37-41.
44. Vikbladh I 1951. Studies on zinc in blood II. Scand Lab Invest 3 (Suppl 2):1.
45. Wintrobe MM 1961. Clinical hematology, edn 5, Lea & Febiger, Philadelphia pp 140.