Statistical analysis of a large file of data from STR profiles of British Caucasians to support forensic casework

International Journal of Legal Medicine

Volumn 109, Issue 4, 1996, Pages 173-177

  Evett, I W ^a   Lambert, J A ^a   Buckleton, J S ^b   Weir, B S ^c  

^a FORENSIC SCIENCE SERVICE   (United Kingdom)

^b MT ALBERT RESEARCH CENTRE   (New Zealand)

^c NORTH CAROLINA STATE UNIVERSITY   (United States)

Author keywords

Caucasian; DNA profiling; Likelihood ratio; PCR; Statistics; STR

Indexed keywords

DNA;

ALLELE; ARTICLE; CAUCASIAN; CONTROLLED STUDY; DNA DETERMINATION; HUMAN; POPULATION GENETICS; PRIORITY JOURNAL; TANDEM REPEAT; UNITED KINGDOM;

ADULT; ALLELES; BLOOD DONORS; CHROMOSOME MAPPING; EUROPEAN CONTINENTAL ANCESTRY GROUP; FEMALE; GENE FREQUENCY; GENETICS, POPULATION; GREAT BRITAIN; HUMANS; MALE; POLYMERASE CHAIN REACTION; REFERENCE VALUES; REPETITIVE SEQUENCES, NUCLEIC ACID;

EID: 0030452584     PISSN: 09379827     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF01225514     Document Type: Article

References (19)

1. Kimpton C, Gill P, Walton A, Urquhart A, Millican ES, Adams M (1993) Automated DNA profiling employing 'multiplexing' amplification of short tandem repeat loci. PCR Methods Appl 3:13-22
2. Kimpton C, Fisher E, Watson S, Adams M, Urquhart A, Lygo JE, Gill P (1994) Evaluation of an automated DNA profiling system employing multiplex amplification of four tetrameric STR loci. Int J Legal Med 106:302-311
3. Lygo JE, Johnson DJ, Holdaway S, Woodroffe S, Whitaker JP, Clayton TM, Kimpton CP, Gill P (1994) The validation of short tandem repeat (STR) loci for the use in forensic casework. Int J Legal Med 107:77-89
4. Gill P, Evett I (1995) Population genetics of short tandem repeat (STR) loci. Genetica 96:69-87
5. Evett IW, Gill PD, Scranage JK, Weir BS (1996) Establishing the robustness of STR statistics for forensic applications. Am J Hum Genet 58:398-407
6. Lee LD, Fairley M, Lambert JA, Evett IW (1996) Validation of a frequency database for four STR loci for use in casework in the Strathclyde Police Forensic Science Laboratory. Forensic Sci Int 79:43-48
7. Foreman LA, Smith AFM, Evett IW (1996) Bayesian analysis of DNA profiling data in forensic identification applications. J R Stat Soc (Series A) (in press)
8. Evett IW, Buckleton JS (1996) Statistical analysis of STR data. In: Carracedo A, Brinkmann B, Bär W (eds) Advances in Forensic Haemogenetics 6, Springer, Berlin New York, pp 79-86
9. Drozd MA, Archard L, Lincoln PJ, Morling N, Nelleman LJ, Phillips C, Soteriou B, Syndercombe Court D (1994) An investigation of the HUMVWA31A locus in British Caucasians. Forensic Sci Int 69:161-170
10. Guo SW, Thompson EA (1992) Performing the exact test of Hardy-Weinberg proportions for multiple alleles. Biometrics 48:361-372
11. Zaykin D, Zhivotovsky L, Weir BS (1995) Exact tests for association between alleles at arbitrary numbers of loci. Genetica 96:169-178
12. Tippett CF, Emerson VJ, Fereday MJ, Lawton F, Lampert SM (1968) The evidential value of the comparison of paint flakes from sources other than vehicles. J Forensic Sci Soc 8:61-65
13. Gaudette BD, Keeping ES (1974) An attempt at determining probabilities in human scalp hair comparison. J Forensic Sci 19:599-606
14. Lambert JA, Scranage JK, Evett IW (1995) Large database experiments to assess the significance of matching DNA profiles. Int J Legal Med 108:8-13
15. Nichols RA, Balding DJ (1991) Effects of population structure on DNA fingerprint analysis in forensic science. Heredity 66: 297-302
16. Berry DA, Evett IW, Pinchin RA (1992) Statistical inference in crime investigations using deoxyribonucleic acid profiling. Appl Statist 41:499-531
17. Balding DJ, Nichols RA (1994) DNA profile match probability calculation: how to allow for population stratification, relatedness, database selection and single bands. Forensic Sci Int 64: 125-140
18. Weir BS, Cockerham CC (1984) Estimating F-statistics for the analysis of population structure. Evolution 38:1358-1370
19. Weir BS (1994) Effects of inbreeding on forensic calculations. Annu Rev Genet 28:597-621