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Volumn 17, Issue 12, 1996, Pages 2747-2752

Site-specific modification of the human N-ras proto-oncogene with each diol epoxide metabolite of benzo[a]pyrene and thermal denaturation studies of the adducted duplexes

Author keywords

[No Author keywords available]

Indexed keywords

ADENINE; DIHYDROXYBENZO[A]PYRENE OXIDE; DNA; ETHYLENE OXIDE; HYDROCARBON; PHOSPHORAMIDIC ACID DERIVATIVE; PURINE DERIVATIVE; PYRENE;

EID: 0030452493     PISSN: 01433334     EISSN: None     Source Type: Journal    
DOI: 10.1093/carcin/17.12.2747     Document Type: Article
Times cited : (27)

References (36)
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    • note
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    • We thank Dr. Barbara Zajc (University of Ljubljana) for the CD data of oligonucleotides containing BaP diol epoxide adducts at the exocyclic amino group of dG
    • We thank Dr. Barbara Zajc (University of Ljubljana) for the CD data of oligonucleotides containing BaP diol epoxide adducts at the exocyclic amino group of dG.
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    • The apurinic site was created through the use of 'dSpacer' available from Glen Research, VA
    • The apurinic site was created through the use of 'dSpacer' available from Glen Research, VA.
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    • Such an effect has been reported in a case unrelated to the present study, where pyrene was tethered at the 5′-terminus via a 5-atom linker: Kierzek,R., Li,Y., Turner,D.H. and Bevilacqua,P.C. (1993) 5′-Amino pyrene provides a sensitive, nonperturbing fluorescent probe of RNA secondary and tertiary structure formation. J. Am. Chem. Soc., 115. 4985-4992.
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