An S. cerevisiae peroxisomal transporter, orthologous to the human adrenoleukodystrophy protein, appears to be a heterodimer of two half ABC transporters: Pxa1p and Pxa2p

Annals of the New York Academy of Sciences

Volumn 804, Issue , 1996, Pages 770-772

  Shani, Noam ^a,b   Sapag, Amalia ^c   Watkins, Paula ^a   Valle, David ^b,c  

^a KENNEDY KRIEGER INSTITUTE   (United States)

^b HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^c JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ABC TRANSPORTER; CARRIER PROTEIN; MEMBRANE PROTEIN; VERY LONG CHAIN FATTY ACID;

ADRENOLEUKODYSTROPHY; CONFERENCE PAPER; NONHUMAN; PEROXISOME; PROTEIN ANALYSIS; PROTEIN ISOLATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SACCHAROMYCES CEREVISIAE;

SACCHAROMYCES CEREVISIAE;

EID: 0030451928     PISSN: 00778923     EISSN: None     Source Type: Book Series    
DOI: 10.1111/j.1749-6632.1996.tb18697.x     Document Type: Conference Paper

References (8)

1. MOSER, J., Y. LUTZ, M. STOECKEL, C. SARDE, C. KRETZ, A. DOUAR, J. LOPEZ, P. AUBOURG & J. MANDEL. 1994. The gene responsible for adrenoleukodystrophy encodes a peroxisomal membrane protein. Hum. Molec. Genet. 3: 265-271.
2. GARTNER, J. & D. VALLE. 1992. Mutations in the 70 K peroxisomal membrane protein gene in Zellweger syndrome. Nat. Genet. 1: 16-23.
3. SHANI, N., P. A. WATKINS & D. VALLE. 1995. PXA1, a possible Saccharomyces cerevisiae ortholog of the human adrenoleukodystrophy gene. Proc. Natl. Acad. Sci. USA 92: 6012-6016.
4. SAURIN, W., W. KOSTER & E. DASSA. 1994. Bacterial binding protein-dependent permeases: Characterization of distinctive signatures for functionally related integral cytoplasmic membrane proteins. Mol. Microbiol. 12: 993-1004.
5. KOSTER, W. & B. BOHM. 1992. Point mutations in two conserved glycine residues within the integral membrane protein FhuB affect iron(II) hydroxamate transport. Mol. Gen. Genet. 232: 399-407.
6. LIGTENBERG, M., S. KEMP, C. O. SARDE, B. VAN GEEL, W. KLEIJER, P. BARTH, J.-L. MANDEL, B. VAN OOST & P. BOLHUIS. 1995. Spectrum of mutations in the gene encoding the adrenoleukodystrophy protein. Am. J. Hum. Genet. 56: 44-50.
7. KOIKE, R., O. ONODERA, H. TABE, K. KENEKO, T. MIYATAKE, J. MOSER, C. SARDE, C. MANDEL & S. TSUJI. 1994. Mutational analysis of adrenoleukodystrophy (ALD) gene in Japanese. Am. J. Hum. Genet. 55: A228.
8. BOSSIER, P., L. PERNANDES, C. VILELA & C. RODRIGUES-POUSADA. 1994. The yeast YKL741 gene situated on the left arm of chromosome XI codes for a homologue of the human ALD protein. Yeast 10: 681-686.