Pharmacodynamics and pharmacokinetics of A-80556 using microdialysis in a Streptococcus pneumoniae meningitis model

Journal of Antimicrobial Chemotherapy

Volumn 38, Issue 6, 1996, Pages 977-985

  Destache, Christopher J ^a   Pakiz, Catherine B ^a   Stoysich, Anne M ^a  

^a CREIGHTON UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

7 (4 AMINO 2 METHYL 1 PYRROLIDINYL) 1 (2,4 DIFLUOROPHENYL) 6 FLUORO 1,4 DIHYDRO 4 OXO 3 QUINOLINECARBOXYLIC ACID; QUINOLINE DERIVED ANTIINFECTIVE AGENT; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; AREA UNDER THE CURVE; ARTICLE; BACTERIAL COUNT; BACTERIAL MENINGITIS; CEREBROSPINAL FLUID; DRUG EFFICACY; DRUG HALF LIFE; DRUG PENETRATION; EXPERIMENTAL INFECTION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; INTRAVENOUS DRUG ADMINISTRATION; MICRODIALYSIS; NONHUMAN; PHARMACODYNAMICS;

ANIMALS; ANTI-INFECTIVE AGENTS; DISEASE MODELS, ANIMAL; FLUOROQUINOLONES; MENINGITIS, BACTERIAL; MICROBIAL SENSITIVITY TESTS; MICRODIALYSIS; PNEUMOCOCCAL INFECTIONS; QUINOLONES; RABBITS; STREPTOCOCCUS PNEUMONIAE;

EID: 0030451596     PISSN: 03057453     EISSN: None     Source Type: Journal    
DOI: 10.1093/jac/38.6.977     Document Type: Article

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