The three dominant female-sterile mutations of the Drosophila ovo gene are point mutations that create new translation-initiator AUG codons

Development

Volumn 122, Issue 12, 1996, Pages 4131-4138

  Mével Ninio, Maryvonne ^a   Fouilloux, Eric ^a   Guénal, Isabelle ^a   Vincent, Alain ^a  

^a CNRS   (France)

Author keywords

Dominant female sterile mutations; Drosophila; ovo; Translation

Indexed keywords

METHIONINE; TRANSCRIPTION FACTOR; ZINC FINGER PROTEIN;

ALLELE; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELL DIFFERENTIATION; CONTROLLED STUDY; DROSOPHILA; FEMALE; GENE MUTATION; GERM LINE; MALE; NONHUMAN; OOCYTE; OVARY DEVELOPMENT; PHENOTYPE; POINT MUTATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; REPORTER GENE; RNA TRANSLATION; START CODON; TRANSLATION INITIATION;

AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; CHROMOSOME MAPPING; CODON, INITIATOR; DNA-BINDING PROTEINS; DROSOPHILA; DROSOPHILA PROTEINS; FEMALE; GENES, REPORTER; INFERTILITY, FEMALE; MOLECULAR SEQUENCE DATA; OOGENESIS; OVARY; POINT MUTATION; PROTEIN BIOSYNTHESIS; READING FRAMES; TRANSCRIPTION FACTORS; TRANSGENES;

EID: 0030451051     PISSN: 09501991     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (40)

1. Bingham, P. M., Levis, R. and Rubin, G. M. (1981). Cloning of DNA sequences from the white locus of D. melanogaster by a novel and general method. Cell 25, 693-704.
2. Busson, D., Gans, M., Komitopoulou, K. and Masson, M. (1983). Genetic analysis of three dominant female sterile mutations located on the X-chromosome of Drosophila melanogaster. Genetics 105, 309-325.
3. D1] dominant female-sterile insertions in Drosophila and their use in generating germ-line chimeras. Development 119, 1359-1369.
4. Coppes, M. J., Campbell, C. E., and Williams, B. R. G. (1993) The role of WT1 in Wilms tumorigenesis. FASEB. J. 7, 886-895.
5. Descombes, P. and Schibler, U. (1991). A liver-enriched transcriptional activator protein, LAP, and a transcriptional inhibitory protein, LIP, are translated from the same mRNA. Cell 67, 569-579.
6. Gans, M., Audit, C. and Masson, M. (1975). Isolation and characterization of sex-linked female-sterile mutants in Drosophila melanogaster. Genetics 81, 683-704.
7. Garflnkel, M. D., Lohe, A. R. and Mahowald, A. P. (1992). Molecular genetics of the Drosophila melanogaster ovo locus, a gene required for sex determination of germline cells. Genetics 130, 791-803.
8. Garfinkel, M. D., Wang, J., Liang, Y. and Mahowald, A.P. (1994). Multiple products from the shavenbaby-ovo gene region of Drosophila melanogaster. relationship to genetic complexity. Mol. Cell. Biol. 14, 6809-6818.
9. Horabin, J. I., Bopp, D., Waterbury, J. and Schedl, P. (1995). Selection and maintenance of sexual identity in the Drosophila germline. Genetics 141, 1521-1535.
10. King, R. C., Mohler, D., Riley, S. F., Storto, P. D. and Nicolazzo, P. S. (1986). Complementation between alleles at the ovarian tumor locus of Drosophila melanogaster. Dev. Genet. 7, 1-20.
11. Klemenz, R., Weber, U. and Gehring, W. (1987). The white gene as a marker in a new P-element vector for gene transfer in Drosophila. Nucl. Acids Res. 15, 3947-3959.
12. Lindsley, D. L. and Zimm, G. (1992). The genome of Drosophila melanogaster. San Diego California: Academic Press, Inc.
13. Little, M., Holmes, G., Bickmore, W., van Heyningen, V., Hastie, N. and Wainwright, B. (1995). DNA binding capacity of the WT1 protein is abolished by Denys-Drash syndrome WT1 point mutations. Hum. Mol. Genet. 4, 351-358.
14. Lopez, A. J. (1995). Developmental role of transcription factor isoforms generated by alternative splicing. Dev. Biol. 172, 396-411.
15. Markussen, F.-H., Michon, A.-M., Breitwieser, W. and Ephrussi, A. (1995). Translational control of oskar generates Short OSK, the isoform that induces pole plasm assembly. Development 121, 3723-3732.
16. McKearin, D. M. and Spradling, A. C. (1990). bag-of-marbles: A Drosophila gene required to initiate both male and female gametogenesis. Genes Dev. 4, 2242-2251.
17. D dominant female-sterile mutations: molecular analysis of revenant alleles. EMBO J. 8, 1549-1558.
18. Mével-Ninio, M., Terracol, R. and Kafatos, F. C. (1991). The ovo gene of Drosophila encodes a zinc finger protein required for female germ line development. EMBO J. 10, 2259-2266.
19. D1 allele on autosomes: use of transformed strains to generate germline mosaics. Mech. Dev. 45, 155-162.
20. Mével-Ninio, M., Terracol, R., Salles, C., Vincent, A. and Payre, F. (1995). ovo, a Drosophila gene required for ovarian development, is specifically expressed in the germline and shares most of its coding sequences with shavenbaby, a gene involved in embryo patterning. Mech. Dev. 49, 83-95.
21. Mohler, J. D. (1977). Developmental genetics of the Drosophila egg. I. Identification of 59 sex-linked cistrons with maternal effects on embryonic development. Genetics 85, 259-272.
22. Oliver, B., Perrimon, N. and Mahowald, A. P. (1987). The ovo locus is required for sex-specific germ line maintenance in Drosophila. Genes Dev. 1, 913-923.
23. Oliver, B., Perrimon, N. and Mahowald, A. P. (1988). Genetic evidence that the sans fille locus is involved in Drosophila sex determination. Genetics 120, 159-171.
24. Oliver, B., Kim, Y.-J. and Baker, B. S. (1993). Sex-lethal, master and slave: a hierarchy of germ-line sex determination in Drosophila. Development 119, 897-908.
25. + in germ-line sex determination depends on X-chromosome number. Development 120, 3185-3195.
26. Pauli, D. and Mahowald, A. P. (1990). Germ line sex determination in Drosophila. Trends Genet. 6, 259-264.
27. Perrimon, N. (1984). Clonal analysis of dominant female-sterile, germline-dependent mutations in Drosophila melanogaster. Genetics 108, 927-939.
28. Perrimon, N., Mohler, J. D., Engstrom, L. and Mahowald, A. P. (1986). X-linked female sterile loci in Drosophila melanogaster. Genetics 113, 695-712.
29. Ptashne, M. and Gann, A. A. F. (1990). Activators and targets. Nature 346, 329-331.
30. Sambrook, J., Fritsch, E. F. and Maniatis, T. (1989) Molecular Cloning: A Laboratory Manual. Cold Spring Harbor, New York: Cold Spring Harbor Laboratory Press.
31. Sanger, F., Nicklen, S. and Coulson, A. R. (1977). DNA sequencing with chain-terminating inhibitors. Proc. Natl Acad. Sci. USA 74, 5463-5467.
32. Schüpbach, T. (1985). Normal female germ cell differentiation requires the female X chromosome to autosome ratio and expression of Sex-lethal in Drosophila melanogaster. Genetics 109, 529-548.
33. Schüpbach, T. and Wieschaus, E. (1989). Female sterile mutations on the second chromosome of Drosophila melanogaster. I. Maternal effect mutations. Genetics 121, 101-117.
34. Schüpbach, T. and Wieschaus, E. (1991). Female sterile mutations on the second chromosome of Drosophila melanogaster. II Mutations blocking oogenesis or altering egg morphology. Genetics 129, 1119-1136.
35. Spradling, A. C. and Rubin, G. M. (1982). Transposition of cloned P elements into Drosophila germ line chromosomes. Science 218, 341-347.
36. Staab, S. and Steinmann-Zwicky, M., (1995). Female germ cells of Drosophila require zygotic ovo and otu product for survival in larvae and pupae respectively. Mech. Dev. 54, 205-210.
37. Steinmann-Zwicky, M., (1988). Sex determination in Drosophila: the X-chromosomal gene liz is required for Sxl activity. EMBO J. 7, 3889-3898.
38. Steinmann-Zwicky, M., Schmid, H. and Nöthiger, R. (1989). Cell-autonomous and inductive signals can determine the sex of the germline of Drosophila by regulating the gene Sex-lethal. Cell 57, 157-166.
39. Steinmann-Zwicky, M., (1994). Sex determination of the Drosophila germline: tra and dsx control somatic inductive signals. Development 120, 707-716.
40. Thummel, C. S., Boulet, A. M. and Lipshitz, H. D. (1988). Vectors for Drosophila P-element mediated transformation and tissue culture transfection. Gene 74, 445-456.