Effects of pulse methylprednisolone on cell adhesion molecules in the synovial membrane in rheumatoid arthritis: Reduced E-selectin and intercellular adhesion molecule 1 expression

Arthritis and Rheumatism

Volumn 39, Issue 12, 1996, Pages 1970-1979

  Youssef, Peter P ^a   Triantafillou, Sophie ^b   Parker, Angela ^b   Coleman, Mark ^b   Roberts Thomson, Peter J ^a   Ahern, Michael J ^c   Smith, Malcolm D ^a  

^a FLINDERS MEDICAL CENTRE   (Australia)

^b Repatriation Hospital   (Australia)

^c FLINDERS UNIVERSITY   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

CD31 ANTIGEN; CELL ADHESION MOLECULE; ENDOTHELIAL LEUKOCYTE ADHESION MOLECULE 1; INTERCELLULAR ADHESION MOLECULE 1; METHYLPREDNISOLONE SODIUM SUCCINATE; PADGEM PROTEIN;

ANTIGEN EXPRESSION; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; DRUG MECHANISM; FEMALE; HUMAN; HUMAN TISSUE; INFLAMMATION; INTRAVENOUS DRUG ADMINISTRATION; MALE; NEUTROPHIL; PRIORITY JOURNAL; RHEUMATOID ARTHRITIS; SYNOVITIS; SYNOVIUM; VASCULAR ENDOTHELIUM;

AGED; AGED, 80 AND OVER; ARTHRITIS, RHEUMATOID; BIOPSY; CELL ADHESION MOLECULES; CELL MOVEMENT; E-SELECTIN; ENDOTHELIUM, VASCULAR; FEMALE; HUMANS; INTERCELLULAR ADHESION MOLECULE-1; JOINTS; MALE; METHYLPREDNISOLONE HEMISUCCINATE; MIDDLE AGED; NEUTROPHILS; SYNOVIAL MEMBRANE;

EID: 0030450782     PISSN: 00043591     EISSN: None     Source Type: Journal    
DOI: 10.1002/art.1780391205     Document Type: Article

References (64)

1. Kitsis E, Weissmann G: The role of the neutrophil in rheumatoid arthritis. Clin Orthop 265:63-72, 1991
2. Schumacher R, Bautista BB, Krauser RE, Mathur AJ, Gall EP: Histologic appearance of the synovium in early rheumatoid arthritis. Semin Arthritis Rheum 23 (suppl):3-10, 1994
3. Weiss SJ, Ward PA: Immune complex induced generation of oxygen metabolites by human neutrophils. J Immunol 129:309-313, 1982
4. Chatham WW, Swaim R, Frohsin H Jr, Heck LW, Miller EJ, Blackburn WD Jr: Degradation of human articular cartilage by neutrophils in synovial fluid. Arthritis Rheum 36:51-58, 1993
5. Ugai K, Ishikawa H, Hirohata K, Shirane H: Interaction of polymorphonuclear leukocytes with immune complexes trapped in rheumatoid articular cartilage. Arthritis Rheum 26:1434-1441, 1983
6. McCurdy L, Chatham WW, Blackburn WD Jr: Rheumatoid synovial fibroblast adhesion to human articular cartilage: enhancement by neutrophil proteases. Arthritis Rheum 38:1694-1700, 1995
7. Butcher EC: Leukocyte-endothelial cell recognition: three (or more) steps to specificity and diversity. Cell 67:1033-1036, 1991
8. Springer TA: Traffic signals for lymphocyte recirculation and leukocyte emigration: the multistep paradigm. Cell 76:301-314, 1994
9. Ley K, Tedder TF: Leukocyte interaction with vascular endothelium: new insights into selectin-mediated attachment and rolling. J Immunol 155:525-528, 1995
10. Bevilacqua MP, Nelson RM: Selectins. J Clin Invest 91:379-387, 1993
11. Muller WA, Weigl SA, Deng X, Phillips DM: PECAM-1 is required for transendothelial migration of leukocytes. J Exp Med 178:449-460, 1993
12. Mulligan MS, Varani J, Dame MK, Lane CL, Smith CW, Anderson DC, Ward PA: Role of endothelial-leukocyte adhesion molecule 1 (ELAM-1) in neutrophil-mediated lung injury in rats. J Clin Invest 88:1396-1406, 1991
13. Bevilacqua MP, Pober JS, Wheeler ME, Cotran RS, Gimbrone MA: Interleukin 1 acts on cultured human vascular endothelium to increase the adhesion of polymorphonuclear leukocytes, monocytes, and related leukocyte cell lines. J Clin Invest 76:2003-2011, 1985
14. Dustin ML, Rothlein R, Bhan AK, Dinarello CA, Springer TA: Induction by IL-1 and interferon, tissue distribution, biochemistry, and function of a natural adherence molecule (ICAM-1). J Immunol 137:245-254, 1986
15. Johnson BA, Haines GK, Harlow LA, Koch AE: Adhesion molecule expression in human synovial tissue. Arthritis Rheum 36:137-146, 1993
16. Koch AE, Burrows JC, Haines GK, Carlos TM, Harlan JM, Leibovich SJ: Immunolocalization of endothelial and leukocyte adhesion molecules in human rheumatoid and osteoarthritic synovial tissues. Lab Invest 64:313-320, 1991
17. Szekanecz Z, Haines GK, Lin TR, Harlow LA, Goerdt S, Rayan G, Koch AE: Differential distribution of intercellular adhesion molecules (ICAM-1, ICAM-2, and ICAM-3) and the MS-1 antigen in normal and diseased human synovia: their possible pathogenetic and clinical significance in rheumatoid arthritis. Arthritis Rheum 37:221-231, 1994
18. Chu CQ, Field M, Feldmann M, Maini RN: Localization of tumor necrosis factor α in synovial tissues and at the cartilage-pannus junction in patients with rheumatoid arthritis. Arthritis Rheum 34:1125-1132, 1991
19. Ioffreda MD, Albelda SM, Elder DE, Radu A, Leventhal LC, Zweiman B, Murphy GF: TNFα induces E-selectin expression and PECAM-1 (CD31) redistribution in extracutaneous tissues. Endothelium 1:47-54, 1993
20. Kriegsmann J, Keyszer GM, Geiler T, Lagoo AS, Lagoo-Deenadayalan S, Gay RE, Gay S: Expression of E-selectin messenger RNA and protein in rheumatoid arthritis. Arthritis Rheum 38:750-754, 1995
21. Veale D, Yanni G, Rogers S, Barnes L, Bresnihan B, Fitzgerald O: Reduced synovial membrane macrophage numbers, ELAM-1 expression, and lining layer hyperplasia in psoriatic arthritis as compared with rheumatoid arthritis. Arthritis Rheum 36:893-900, 1993
22. Hale LP, Martin ME, McCollum DE, Nunley JA, Springer TA, Singer KH, Haynes BF: Immunohistologic analysis of the distribution of cell adhesion molecules within the inflammatory synovial microenvironment. Arthritis Rheum 32:22-30, 1989
23. Tessier P, Audette M, Cattaruzzi P, McColl SR: Up-regulation by tumor necrosis factor α of intercellular adhesion molecule 1 expression and function in synovial fibroblasts and its inhibition by glucocorticoids. Arthritis Rheum 36:1528-1539, 1993
24. Lindsley HB, Smith DD, Cohick CB, Koch AE, Davis LS: Proinflammatory cytokines enhance human synoviocyte expression of functional intercellular adhesion molecule-1 (ICAM-1). Clin Immunol Immunopathol 68:311-320, 1993
25. Gerritsen ME, Kelley KA, Ligon G, Perry CA, Shen C-P, Szczepanski A, Carley WW: Regulation of the expression of intercellular adhesion molecule 1 in cultured human endothelial cells derived from rheumatoid synovium. Arthritis Rheum 36:593-602, 1993
26. El-Gabalawy H, Gallatin M, Vazeux R, Peterman G, Wilkins J: Expression of ICAM-R (ICAM-3), a novel counter-receptor for LFA-1, in rheumatoid and nonrheumatoid synovium: comparison with other adhesion molecules. Arthritis Rheum 37:846-854, 1994
27. Tessier PA, Cattaruzzi P, McColl SR: Inhibition of lymphocyte adhesion to cytokine-activated synovial fibroblasts by glucocorticoids involves the attenuation of vascular cell adhesion molecule 1 and intercellular adhesion molecule 1 gene expression. Arthritis Rheum 39:226-234, 1996
28. Szekanecz S, Haines GK, Harlow LA, Shah MR, Fong TW, Fu R, Lin SJ-W, Koch AE: Increased synovial expression of the adhesion molecules CD66a, CD66b, and CD31 in rheumatoid and osteoarthritis. Clin Immunol Immunopathol 76:180-186, 1995
29. Smith MD, Ahern MJ, Roberts-Thomson PJ: Pulse methylprednisolone therapy in rheumatoid arthritis: unproved therapy, unjustified therapy, or effective adjunctive treatment? Ann Rheum Dis 49:265-267, 1990
30. Smith MD, Bertouch JV, Smith AM, Weatherall M, Ahern MJ, Brooks PM, Roberts-Thomson PJ: The clinical and immunological effects of pulse methylprednisolone therapy in rheumatoid arthritis. I. Clinical effects. J Rheumatol 15:229-232, 1988
31. Smith MD, Ahern MJ, Brooks PM, Roberts-Thomson PJ: The clinical and immunological effects of pulse methylprednisolone therapy in rheumatoid arthritis. II. Effects on immune and inflammatory indices in peripheral blood. J Rheumatol 15:233-237, 1988
32. Smith MD, Ahern MJ, Brooks PM, Roberts-Thomson PJ: The clinical and immunological effects of pulse methylprednisolone therapy in rheumatoid arthritis. III. Effects on immune and inflammatory indices in synovial fluid. J Rheumatol 15:238-241, 1988
33. Youssef PP, Roberts-Thomson PJ, Ahern MJ, Smith MD: Pulse methylprednisolone in rheumatoid arthritis: effects on peripheral blood and synovial fluid neutrophil surface phenotype. J Rheumatol 22:2065-2071, 1995
34. Youssef PP, Cormack J, Evill CA, Peter DT, Roberts-Thomson PJ, Ahern MJ, Smith MD: Neutrophil trafficking into inflamed joints in patients with rheumatoid arthritis, and the effect of methylprednisolone. Arthritis Rheum 39:216-225, 1996
35. Youssef PP, Haynes DR, Triantafillou S, Parker A, Gamble JR, Roberts-Thomson PJ, Ahern MJ, Smith MD: Effects of pulse methylprednisolone on proinflammatory mediators in peripheral blood, synovial fluid and the synovial membrane in rheumatoid arthritis: decreased expression of TNFα. Submitted for publication
36. Kohler G, Milstein C: Continuous cultures of fused cells secreting antibody of predefined specificity. Nature 256:495-497, 1975
37. Arnett FC, Edworthy SM, Bloch DA, McShane DJ, Fries JF, Cooper NS, Healey LA, Kaplan SR, Liang MH, Luthra HS, Medsger TA Jr, Mitchell DM, Neustadt DH, Pinals RS, Schaller JG, Sharp JT, Wilder RL, Hunder GG: The American Rheumatism Association 1987 revised criteria for the classification of rheumatoid arthritis. Arthritis Rheum 31:315-324, 1988
38. Smith MD, Chandran G, Youssef PP, Darby T, Ahern MJ: Day case knee arthroscopy under regional anaesthesia performed by rheumatologists. Aust N Z J Med 26:108-109, 1996
39. Smith MD, O'Donell J, Highton J, Palmer DG, Rosenbilds M, Roberts-Thomson PJ: Immunohistochemical analysis of synovial membranes from inflammatory and noninflammatory arthritides: scarcity of CD5 positive B cells and IL2 receptor bearing T cells. Pathology 24:19-26, 1992
40. Skinner JM, Zhao Y, Coventry B, Bradley J: Videoimage analysis in pathology. Dis Markers 11:53-70, 1993
41. Cronstein BN, Weissmann G: The adhesion molecules of inflammation. Arthritis Rheum 36:147-157, 1993
42. Cronstein BN, Kimmel SC, Levin RI, Martiniuk F, Weissmann G: A mechanism for the antiinflammatory effects of corticosteroids: the glucocorticoid receptor regulates leukocyte adhesion to endothelial cells and expression of endothelial-leukocyte adhesion molecule 1 and intercellular adhesion molecule 1. Proc Natl Acad Sci U S A 89:9991-9995, 1992
43. Kukielka GL, Lane CL, Manning AM, Michael LH, Entman MC, Smith CW, Anderson DC: Induction of myocardial ELAM-1 by ischaemia and reperfusion (abstract). FASEB J 6:A1060, 1992
44. Grober JS, Bowen BL, Ebling H, Athey B, Thompson CB, Fox DA, Stoolman LM: Monocyte-endothelial adhesion in chronic rheumatoid arthritis. J Clin Invest 91:2609-2619, 1993
45. Labow MA, Norton CR, Rumberger JM, Lombard-Gillooly KM, Shuster DJ, Hubbard J, Bertko R, Knaack PA, Terry RW, Harbison ML, Kontgen F, Stewart CL, McIntyre KW, Will PC, Burns DK, Wolitzky BA: Characterisation of E-selectin-deficient mice: demonstration of overlapping function of the endothelial selectins. Immunity 1:709-720, 1994
46. Mayadas TN, Johnson RC, Rayburn H, Hynes RO, Wagner DD: Leukocyte rolling and extravasation are severely compromised in P selectin-deficient mice. Cell 74:541-554, 1993
47. 2) on human neutrophils. J Exp Med 173:1493-1500, 1991
48. Kavanaugh AF, Davis LS, Nichols LA, Norris SH, Rothlein R, Scharschmidt LA, Lipsky PE: Treatment of refractory rheumatoid arthritis with a monoclonal antibody to intercellular adhesion molecule 1. Arthritis Rheum 37:992-999, 1994
49. Lawrence MB, Springer TA: Leukocytes roll on a selectin at physiologic flow rates: distinction from and prerequisite for adhesion through integrins. Cell 65:859-873, 1991
50. Gaboury JP, Kubes P: Reductions in physiological shear rates lead to CD11/CD18-dependent, selectin-independent leukocyte rolling in vivo. Blood 83:345-350, 1994
51. Bullard DC, Qin L, Lorenzo I, Ouinlin WM, Doyle NA, Bosse R, Vestweber D, Doerschuk CM, Beaudet AL: P-selectin/ICAM-1 double mutant mice: acute emigration of neutrophils into the peritoneum is completely absent but is normal into pulmonary alveoli. J Clin Invest 95:1782-1788, 1995
52. Brennan FM, Field M, Chu CQ, Feldmann M, Maini RN: Cytokine expression in rheumatoid arthritis. Br J Rheumatol 30 (suppl 1):76-80, 1991
53. Jonat C, Rahmsdorf HJ, Park K-K, Cato ACB, Gebel S, Ponta H, Herrlich P: Antitumour promotion and inflammation: downmodulation of AP-1 (Fos-Jun) activity by glucocorticoid hormone. Cell 62:1189-1204, 1990
54. Mukaida N, Morita M, Ishikawa Y, Rice N, Okamoto S, Kasahara T, Matsushima K: Novel mechanism of glucocorticoid-mediated gene repression: nuclear factor-κB is target for glucocorticoid-mediated interleukin 8 gene repression. J Biol Chem 269:13289-13295, 1994
55. Read MA, Whitley MZ, Williams AJ, Collins T: NF-κB and IκBα: an inducible regulatory system in endothelial activation. J Exp Med 179:503-512, 1994
56. Voraberger G, Schafer R, Stratowa C: Cloning of the human gene for intercellular adhesion molecule 1 and analysis of its 5′-regulatory region: induction by cytokines and phorbol ester. J Immunol 147:2777-2786, 1991
57. Degitz K, Llian-Jie L, Caughman SW: Cloning and characterization of the 5′-transcriptional regulatory region of the human intercellular adhesion molecule 1 gene. J Biol Chem 266:14024-14030, 1991
58. Staunton DE, Marlin SD, Stratowa C, Dustin ML, Springer TA: Primary structure of ICAM-1 demonstrates interaction between members of the immunoglobulin and integrin supergene families. Cell 52:925-933, 1988
59. Shaw G, Kamen R: A conserved AU sequence from the 3Z′-untranslated region of GM-CSF mRNA mediates selective mRNA degradation. Cell 46:659-667, 1986
60. Malter JS: Identification of AUUUA-specific messenger RNA binding protein. Science 246:664-666, 1989
61. Oda T, Katari M: Inhibition site of dexamethasone on extravasation of polymorphonuclear leukocytes in the hamster cheek pouch microcirculation. J Leukoc Biol 52:337-342, 1992
62. Vaporciyan AA, DeLisser HM, Yan HC, Mendiguren II, Jones ML, Ward PA, Albelda SM: Involvement of platelet-endothelial cell adhesion molecule-1 in neutrophil recruitment in vivo. Science 262:1580-1582, 1993
63. Corkill MM, Kirkham BW, Haskard DO, Barbatis C, Gibson T, Panayi GS: Gold treatment of rheumatoid arthritis decreases synovial expression of the endothelial leukocyte adhesion receptor ELAM-1. J Rheumatol 18:1453-1460, 1991
64. Paleolog EM, Taylor PC, Hunt M, Tak PP, Elliott MJ, Feldmann M, Breedveld FC, Maini RN: Treatment of rheumatoid arthritis with antibody to TNFα decreases expression and shedding of E-selectin (abstract). Arthritis Rheum 38 (suppl 9):S279, 1995