Somatosensory afferent inputs release 5-HT and NA from the spinal cord

Neurochemical Research

Volumn 21, Issue 12, 1996, Pages 1515-1519

  Men, Disheng ^a,b   Matsui, Aiko ^a   Matsui, Yoichiro ^a  

^a SHOWA UNIVERSITY   (Japan)

^b UNIVERSITY OF VIRGINIA   (United States)

Author keywords

analgesia; noradrenaline; peripheral electrical stimulation; Serotonin; spinal cord

Indexed keywords

NORADRENALIN; SEROTONIN;

AFFERENT NERVE GROUP 1; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; ELECTROCHEMICAL DETECTION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MICRODIALYSIS; MYELINATED NERVE; NOCICEPTIVE STIMULATION; NONHUMAN; NORADRENALIN RELEASE; NORADRENERGIC SYSTEM; PRIORITY JOURNAL; RAT; SEROTONIN RELEASE; SEROTONINERGIC SYSTEM; SOMATOSENSORY SYSTEM; SPINAL CORD;

AFFERENT PATHWAYS; ANIMALS; ELECTRIC STIMULATION; KINETICS; NERVE FIBERS, MYELINATED; NOREPINEPHRINE; RATS; RATS, WISTAR; SEROTONIN; SPINAL CORD;

ANIMALIA;

EID: 0030450772     PISSN: 03643190     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF02533099     Document Type: Article

References (21)

1. Dubner, R., and Bennett, G. J. 1983. Spinal and trigeminal mechanisms of nociception. Ann. Rev. Neurosci. 6:381-418.
2. Hayes, R. L., Bennett, G. J., Newlon, P. G., and Mayer, D. J. 1978. Behavioural and physiological studies of non-narcotic analgesia in the rat elicited by certain environmental stimuli. Brain Res. 155:69-90.
3. Tomlinson, R. W. W., Gray, B. G., and Dostrovsky, J. O. 1983. Inhibition of rat spinal dorsal horn neurons by non-segmental, noxious cutaneous stimuli. Brain Res. 279:291-294.
4. Lewis, J. W., Terman, G. W., Watkins, L. R., Mayer, D. J., and Liebeskind, J. C. 1983. Opioid and non-opioid mechanisms of footshock-induced analgesia: role of the spinal dorsolateral funiculus. Brain Res. 267:139-144.
5. Watkins, L. R., Cobelli, D. A., and Mayer, D. J. 1982. Opiate vs non-opiate footshock induced analgesia (FSIA): Descending and intraspinal components. Brain Res. 245:97-106.
6. Anderson, S. D., Basbaum, A. I., and Fields, H. L. 1977. Response of medullary raphe neurons to peripheral stimulation and to systemic opiates. Brain Res. 123:363-368.
7. Guibaud, G., Peschanski, M., Gautron, M., and Binder, D. 1980. Responses of neurons of the nucleus raphe magnus to noxious stimuli. Neurosci. Lett. 17:149-154.
8. Hirata, H., and Aston-Jones, G. 1994. A novel long-latency response of locus coeruleus neurons to noxious stimuli: mediation by peripheral C-fibers. J. Neurophysiol. 71:1752-1761.
9. Watkins, L. R., Young, E. G., Kinscheck, I. B., and Mayer, D. J. 1983. The neural basis of footshock analgesia: the role of specific ventral medullary nuclei. Brain Res. 276:305-315.
10. Yaksh, T. L., Hammond, D. L., and Tyce, G. M. 1981. Functional aspects of bulbospinal monoaminergic projections in modulating processing of somatosensory information. Federation Proc. 40: 2786-2794.
11. Kokubu, T., Ishii, N., and Tsuruoka, M. 1987. Suppression of the tail flick reflex by selective stimulation of Aδ afferent nerve fibers. J. Showa Univ. Dent. Soc 7:37-44.
12. Men, D-S., and Matsui, Y. 1994. Peripheral nerve stimulation increases serotonin and dopamine metabolites in rat spinal cord. Brain Res. Bull. 33:625-632.
13. Bowker, R. M., Westlund, K. N., and Coulter, J. D. 1981. Origins of serotonergic projections to the spinal cord in rat: An immunocytochemical retrograde transport study. Brain Res. 226:187-199.
14. Marlier, L., Sandillon, F., Poulat, P., Rajaofetra, N., Geffard, M., and Privat, A. 1991. Serotonergic innervation of the dorsal horn of the rat spinal cord: A light- and electro-microscope immunocytochemical study. J. Neurocytol. 20:310-322.
15. Men, D-S., and Matsui, Y. 1994. Activation of descending noradrenergic system by peripheral nerve stimulation. Brain Res. Bull. 34:177-182.
16. Cannon, J. T., Lewis, J. W., Weinberg, V. E., and Liebeskind, J. C. 1983. Evidence for the independence of brainstem mechanisms mediating analgesia induced by morphine and two forms of stress. Brain Res. 269:231-236.
17. Watkins, L. R., Johannessen, J. N., Kinscheck, I. B., and Mayer, D. J. 1984. The neurochemical basis of footshock analgesia: the role of spinal cord serotonin and norepinephrine. Brain Res. 290: 107-117.
18. Cheng, R. S. S., and Pomeranz, B. 1981. Monoaminergic mechanism of electroaccupuncture analgesia. Brain Res. 215:77-92.
19. Danysz, W., Minor, B. G., Jonsson, G., Post, C., and Archer, T. 1986. Spinal noradrenergic neurotransmission and the analgesia induced by foot shock. Brain Res. 365:169-173.
20. Hutson, P. H., Tricklebank, M. D., and Curzon, G. 1982. Enhancement of footshock induced analgesia by spinal 5,7-dihydroxytryptamine lesions. Brain Res. 237:367-372.
21. Tyce, G. M., and Yaksh, T. L. 1981. Monoamine release from cat spinal cord by somatic stimuli: an intrinsic modulatory system. J. Physiol. 314:513-529.