Folate absorption in the jejunum of chronic ethanol-fed rats: In vivo Studies

Annals of Nutrition and Metabolism

Volumn 40, Issue 5, 1996, Pages 277-282

  Fernandez Borrachero, O ^a   Rubio, J M ^a   Delgado, M J ^a   Carreras Sanchez O ^a   Murillo, M L ^a  

^a UNIVERSITY OF SEVILLE   (Spain)

Author keywords

Ethanol; Folic acid absorption; Jejunum; MTHF absorption

Indexed keywords

5 METHYLTETRAHYDROFOLIC ACID; ALCOHOL; FOLIC ACID;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; JEJUNUM; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; SMALL INTESTINE ABSORPTION;

EID: 0030449819     PISSN: 02506807     EISSN: 14219697     Source Type: Journal    
DOI: 10.1159/000177968     Document Type: Article

References (23)

1. Halsted CH: Alcoholism and folate homeostasis; in Halsted CH. Rucker RB (eds): Nutrition and the Origins of Disease. San Diego, Academic Press, 1989, pp 249-266.
2. Lindenbaum J: Folate and vitamin B12 déficiences in alcoholism. Semin Hematol 1980;17:119-129.
3. Steinberg SE, Campbell CL, Will-man RS: The role of the enterohe-patic cycle in folate supply to tumor in rats. Br J Haematol 1982:50:309-316.
4. Weir DG, McGing PG, Scott JM: Folate metabolism, the enterohepat-ic circulation and alcohol. Biochem Pharmacol 1985;34:1-7.
5. Halsted Ch, Robles EA, Mezey A: Decreased jejunal uptake of labeled folic acid (H-'-PGA) in alcoholic patients: Roles of alcohol and malnutrition. N Engl J Med 1971:285: 701-706.
6. McMartin KE. Collins TD, Eisenga BH. Fortney T, Bats WR, Bairns-father L: Effects of chronic ethanol and diet treatment on urinary folate excretion and development of folate deficiency in the rat. J Nutr 1989; 119:1490-1497.
7. Been A, Swan CHJ, Cooke WT, Blair JA, Matty AJ, Smith ME: Effect of intraluminal pH on the absorption of ptcroylmonoglutamil acid. Br Med J 1971 1148-150.
8. Rosenberg IH: Intestinal absorption of folates; in Johnson L (ed): Folates and Pterins: Nutritional. Pharmacological and Physiological Aspects. New York. Wiley. 1986. vol 3.
9. Naughton CA, Chandler CJ, Du-plantier RB. Halsted CH: Folate absorption in alcoholic pigs: In vitro hydrolysis and transport at the intestinal brush border membrane. Am J Clin Nutr 1989;50:1436-1441.
10. Home DW. Briggs WT. Wagner C: Studies on the transport mechanism of 5-melhyltelrahydrofolic acid in freshly isolated hepalocyles: Effect of ethanol. Arch Biochem Biophys 1979:196:557-565.
11. Reisenauer AM. Buffington CAT. Villanueva JA. Halsted CH: Folate absorption in alcoholic pigs: In vivo perfusion studies. Am J Clin Nutr 1989;50:1429-1435.
12. Hajjar JJ, Tomicic TK: Protein deficiency and the effect of ethanol on leucine absorption across the rat intestine. Nutr Rep Int 1985:31:399-405.
13. Carreras O, Vázquez AL, Rubio JM, Delgado MJ, Murillo ML: Effect of chronic ethanol on O-galactose absorption by the rat whole intestinal surface. Alcohol 1991:9:83-86.
14. Veale WL, Myers RD: Tables for determining grams and caloric values of ethanol solutions. Purdue Neuropsychol Ser 1968:(report 1): 1-4.
15. Ponz F. Ilundain A. Lluch M: Method for successive absorptions with intestinal perfusion in vivo. Rev Esp Fisiol 1979;35:97-104.
16. Carreras O, Murillo ML, Delgado MJ, Bolufcr J: Galactose absorption after jejunoileal bypass in rats. Nutr Repint 1988:38:1219-1229.
17. Waxman S, Screibcr C: Determination of folate by use of radioactive folate binding proteins. Methods Enzymol 1980:66:468-483.
18. Halsted Cl I, Robles EA, Mazcy E: Intestinal malabsorption in folate-deficient alcoholics. Gastroenterology 1973:64:526.
19. Said HM. Strum WB: Effect of ethanol and other aliphatic alcohols on the intestinal transport of folates. Digestion 1986:35:129-135.
20. McMartin KE: Increased urinary folate excretion and decreased plasma folate levels in the rat after acute ethanol treatment. Alcohol Clin Exp Res 1984;8:172-178.
21. Lane F, Gott P. Mcguffin R. Eichner ER, Hillman RS: Folic acid metabolism in normal, folate deficient and alcoholic man. BrJ Haematol 1976: 34:489-500.
22. Racusen LC. Krawitt EL: Effect of folate deficiency and ethanol ingestion on folate absorption. Am J Dig Dis 1977;22:915-920.
23. Solomons NW, Chang H, Rosenberg IH: Partial starvation enhances polvglutamyl and monoglutamyl folate absorption in rat intestine (abstract). Gastroenterology 1975:68: 1063.