Local cerebral blood flow in motor neuron disease: Correlation with clinical findings

Journal of the Neurological Sciences

Volumn 144, Issue 1-2, 1996, Pages 64-69

  Kobari, Masahiro ^a   Obara, Katsuyuki ^a   Watanabe, Shigeru ^a   Dembo, Tomohisa ^a   Fukuuchi, Yasuo ^a  

^a KEIO UNIVERSITY   (Japan)

Author keywords

amyotrophic lateral sclerosis; cerebral blood flow; motor neuron disease; thyrotropin releasing hormone; xenon enhanced CT CBF

Indexed keywords

PROTIRELIN; XENON;

ADULT; AGED; AMYOTROPHIC LATERAL SCLEROSIS; ARTICLE; BRAIN BLOOD FLOW; CLINICAL ARTICLE; DEMENTIA; FEMALE; HUMAN; INTRAVENOUS DRUG ADMINISTRATION; MALE; MOTOR NEURON DISEASE; PRIORITY JOURNAL;

AGED; AGING; CEREBROVASCULAR CIRCULATION; FEMALE; HUMANS; INJECTIONS, INTRAVENOUS; MALE; MIDDLE AGED; MOTOR NEURON DISEASE; THYROTROPIN-RELEASING HORMONE; TOMOGRAPHY, X-RAY COMPUTED;

EID: 0030449312     PISSN: 0022510X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0022-510X(96)00151-7     Document Type: Article

References (20)

1. Brooks B.R. A summary of the current position of TRH in ALS therapy. Ann. N.Y. Acad. Sci. 553:1989;431-461.
2. Brownell B., Oppenheimer D.R., Hughes J.T. The central nervous system in motor neurone disease. J. Neurol. Neurosurg. Psychiatry. 33:1970;338-357.
3. Dalakas M.C., Hatazawa J., Brooks R.A., Di Chiro G. Lowered cerebral glucose utilization in amyotrophic lateral sclerosis. Ann. Neurol. 22:1987;580-586.
4. Engel W.K., Siddique T., Nicoloff J.T. Effect on weakness and spasticity in amyotrophic lateral sclerosis of thyrotropin-releasing hormone. Lancet. 2:1983;73-75.
5. Hammer R.P. Jr., Tomiyasu U., Scheibel A.B. Degeneration of the human Betz cell due to amyotrophic lateral sclerosis. Exp. Neurol. 63:1979;336-346.
6. Hoffman J.M., Mazziotta J.C., Hawk T.C., Sumida R. Cerebral glucose utilization in motor neuron disease. Arch. Neurol. 49:1992;849-854.
7. Kew J.J.M., Brooks D.J., Passingham R.E., Rothwell J.C., Frackowiak R.S.J., Leigh P.N. Cortical function in progressive lower motor neuron disorders and amyotrophic lateral sclerosis: a comparative PET study. Neurology. 44:1994;1101-1110.
8. Kobari M., Fukuuchi Y., Shinohara T., Nogawa S., Takahashi K. Local cerebral blood flow and its response to intravenous levodopa in progressive supranuclear palsy: comparison with Parkinson's disease. Arch. Neurol. 49:1992;725-730.
9. Kobari M., Fukuuchi Y., Shinohara T., Obara K., Nogawa S. Levodopa-induced local cerebral blood flow changes in Parkinson's disease and related disorders. J. Neurol. Sci. 128:1995;212-218.
10. Ludolph A.C., Langen K.J., Regard M., Herzog H., Kemper B., Kuwert T., Böttger I.G., Feinendegen L. Frontal lobe function in amyotrophic lateral sclerosis: a neuropsychologic and positron emission tomography study. Acta Neurol. Scand. 85:1992;81-89.
11. Luís M.L.S., Hormigo A., Maurício C., Alves M.M., Serrão R. Magnetic resonance imaging in motor neuron disease. J. Neurol. 237:1990;471-474.
12. Manaker S., Shulman L.H., Winokur A., Rainbow T.C. Autoradiographic localization of thyrotropin-releasing hormone receptors in amyotrophic lateral sclerosis spinal cord. Neurology. 35:1985;1650-1653.
13. Meyer J.S., Shinohara T., Imai A., Kobari M., Sakai F., Hata T., Oravez W.T., Timpe G.M., Deville T., Solomon E. Imaging local cerebral blood flow by Xenon-enhanced computed tomography: technical optimization procedures. Neuroradiology. 30:1988;283-292.
14. Mitsuyama Y. Presenile dementia with motor neuron disease in Japan: clinico-pathological review of 26 cases. J. Neurol. Neurosurg. Psychiatry. 47:1984;953-959.
15. Oba H., Araki T., Ohtomo K., Monzawa S., Uchiyama G., Koizumi K., Nogata Y., Kachi K., Shiozawa Z., Kobayashi M. Amyotrophic lateral sclerosis: T2 shortening in motor cortex at MR imaging. Radiology. 189:1993;843-846.
16. 123I-IMP in patients with degenerative dementia. A.J.N.R. 12:1991;513-520.
17. Tanaka M., Kondo S., Hirai S., Sun X., Yamagishi T., Okamoto K. Cerebral blood flow and oxygen metabolism in progressive dementia associated with amyotrophic lateral sclerosis. J. Neurol. Sci. 120:1993;22-28.
18. Udaka F., Kameyama M., Tomonaga M. Degeneration of Betz cells in motor neuron disease: a Golgi study. Acta Neuropathol. (Berl.). 70:1986;289-295.
19. 99mTc]-d,l-HMPAO SPECT study. J. Neurol. Sci. 107:1992;19-28.
20. Yamane K., Osawa M., Kobayashi I., Maruyama S. Treatment of amyotrophic lateral sclerosis with thyrotropin-releasing hormone (TRH). Jpn. J. Psychiatry Neurol. 40:1986;179-187.