A probable cis-regulatory element on yeast mitochondrial DNA responsible for cAMP-mediated transcription

Current Genetics

Volumn 30, Issue 6, 1996, Pages 493-501

  Iqbal, Jabed ^a   Gérard, Hervé C ^a   Rahman, Mahboob U ^a   Hudson, Alan P ^a,b  

^a DREXEL UNIVERSITY COLLEGE OF MEDICINE   (United States)

^b DEPARTMENT OF VETERANS AFFAIRS   (United States)

Author keywords

Cis element; Mitochondria; Saccharomyces cerevisiae; Transcription

Indexed keywords

CIS ACTING ELEMENT; CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE; FUNGAL DNA; MITOCHONDRIAL DNA; PHOSPHOPROTEIN;

ARTICLE; CODING; CONTROLLED STUDY; DNA TRANSCRIPTION; ENZYME ACTIVITY; GEL MOBILITY SHIFT ASSAY; GENE EXPRESSION; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN DNA INTERACTION; REGULATOR GENE; SACCHAROMYCES CEREVISIAE; SEQUENCE ANALYSIS; SEQUENCE HOMOLOGY; TRANSACTIVATION; TRANSCRIPTION REGULATION;

CYCLIC AMP; CYCLIC AMP-DEPENDENT PROTEIN KINASES; DNA, MITOCHONDRIAL; DNA-BINDING PROTEINS; GENE EXPRESSION REGULATION, FUNGAL; MUTATION; PHOSPHORYLATION; PROTEIN BINDING; REGULATORY SEQUENCES, NUCLEIC ACID; SACCHAROMYCES CEREVISIAE; TRANSCRIPTION, GENETIC;

SACCHAROMYCES CEREVISIAE; VERTEBRATA;

EID: 0030449151     PISSN: 01728083     EISSN: None     Source Type: Journal    
DOI: 10.1007/s002940050161     Document Type: Article

References (54)

1. Birky CP (1975) Effects of glucose repression on the transmission of mitochondrial genes in yeast (Saccharomyces cerevisiae). Genetics 80:695-709
2. Biswas T, Getz G (1986) Nucleotides flanking the promoter sequences influence the transcription of the yeast mitochondrial gene coding for ATPase subunit 9. Proc Natl Acad Sci USA 83:270-274
3. Bradford M (1976) A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 72:248-254
4. Broach JR (1992) Ras-related signaling processes in Saccharomyces cerevisiae. Curr Opin Genet Dev 1:370-377
5. Cantwell R, McEntee CM, Hudson AP (1992) Regulation of mitochondrial transcription during the stringent response in yeast. Curr Genet 21:241-247
6. Christianson T, Rabinowitz M (1983) Identification of multiple transcriptional initiation sites on the yeast mitochondrial genome by in vitro capping with guanylyl transferase. J Biol Chem 258: 14025-14033
7. Clayton DA (1992) Transcription and replication of animal mitochondrial DNAs. In: Wolstenholme DR, Jeon KW (eds) Mitochondrial genomes. Int Rev Cytol 141:217-232
8. Costanzo MC, Fox TD (1990) Control of mitochondrial gene expression in Saccharomyces cerevisiae. Annu Rev Genet 24:91-113
9. Crombrugghe B de, Busby S, Bue H (1984) Cyclic AMP receptor protein: role in transcriptional activation. Science 224:831-838
10. Daga A, Micol V, Hess D, Aebersold R, Attardi G (1993) Molecular characterization of the transcription termination factor from human mitochondria. J Biol Chem 268:8123-8130
11. Dieckmann CL, Staples RR (1993) Regulation of mitochondrial gene expression in Saccharomyces cerevisiae. Int Rev Cytol 152: 145-181
12. Hudspeth MES, Shumard DS, Tatti KM, Grossman L (1980) Rapid purification of yeast mitochondrial DNA in high yield. Biochem Biophys Acta 610:221-288
13. Iqbal J, Hudson AP (1996) An in vitro transcription assay for yeast mitochondria using organellar lysates. Anal Biochem (in press)
14. Jang SH, Jaehning JA (1991) The yeast mitochondrial RNA polymerase specificity factor, MTF1, is similar to bacterial factors. J Biol Chem 266:22671-22677
15. Keegan L, Gill G, Ptashne M (1986) Separation of DNA-binding from transcription-activating functions of a eukaryotic regulatory protein. Science 231:699-704
16. Kelly JL, Greenleaf AL, Lehman IR (1987) Isolation of the nuclear gene encoding a subunit of the yeast mitochondrial RNA polymerase. J Biol Chem 261:10348-10351
17. Lamb MR, Anziano PQ, Glaus KR, Hanson DK, Klapper HJ, Perlman PS, Mahler HR (1983) Functional domains in introns: RNA processing intermediates in cis- and trans-acting mutants in the penultimate intron of the mitochondrial gene for cytochrome b. J Biol Chem 258:1991-1998
18. Lisowsky T (1990) Molecular analysis of the mitochondrial transcription factor mtf2 of Saccharomyces cerevisiae. Mol Gen Genet 220:186-190
19. Lisowsky T, Michaelis G (1988) A nuclear gene essential for mitochondrial DNA replication supresses a defect of mitochondrial transcription in Saccharomyces cerevisiae. Mol Gen Genet 214:218-223
20. Locker J, Rabinowitz M (1981) Transcription in yeast mitochondria: analysis of the 21S rRNA region and its transcripts. Plasmid 6:302-314
21. Mangus DA, Jang SH, Jaehning JA (1994) Release of the yeast mitochondrial RNA polymerase specificity factor from transcription complexes. J Biol Chem 269:26568-26574
22. Masters BS, Stohl LL, Clayton DA (1987) Yeast mitochondrial RNA polymerase is homologous to those encoded by bacteriophages T3 and T7. Cell 51:89-99
23. McEntee CM, Cantwell R, Thomas LC, Hudson AP (1989) Mitochondrial rRNA-containing petite strains of yeast (S. cerevisiae) show a normal nuclear-mitochondrial stringent response. Biochem Biophys Res Comm 164:362-369
24. McEntee CM, Cantwell R, Rahman MU, Hudson AP (1993) Transcription of the yeast mitochondrial genome requires cAMP. Mol Gen Genet 214:213-224
25. McEntee CM, Cantwell R, Hudson AP (1994) Regulation of stringent mitochondrial transcription in yeast following amino-acid deprivation. Gene 141:129-132
26. Mueller DM, Getz G (1986) Transcriptional regulation of the mitochondrial genome of the yeast Saccharomyces cerevisiae. J Biol Chem 261:11756-11765
27. Müller G, Bandlow W (1987) Protein phosphorylation in yeast mitochondria. cAMP-dependence, sub-mitochondrial localization, and substrates of mitochondrial protein kinases. Yeast 3:161-174
28. Müller G, Bandlow W (1989) An amphitrophic cAMP-binding protein in yeast mitochondria. I. Synergistic control of the intramitochondrial location by calcium and phospholipid. Biochemistry 28:9957-9967
29. Nagley P (1991) Coordination of gene expression in the formation of mammalian mitochondria. Trends Genet 7:1-4
30. Neuman-Silberberg FS, Bhattacharya S, Broach JR (1995) Nutrient availability and the RAS/cAMP pathway both induce expression of ribosomal protein genes in Saccharomyces cerevisiae but by different mechanisms. Mol Cell Biol 15:3187-3196
31. Parikh VS, Morgan MM, Scott R, Clements LS, Butow RA (1987) The mitochondrial genotype can influence nuclear gene expression in yeast. Science 235:576-580
32. Parisi MA, Clayton DA (1991) Similarity of human mitochondrial transcription factor 1 to high-mobility group proteins. Science 252:965-969
33. Parisi MA, Xu B, Clayton DA (1993) A human mitochondrial transcriptional activator can functionally replace a yeast mitochondrial HMG-box protein both in vivo and in vitro. Mol Cell Biol 13:1951-1961
34. Rahman MU, Hudson AP (1995) Nature and transcriptional role of catalytic subunits of yeast mitochondrial cAMP-dependent protein kinase. Biochem Biophys Res Commun 206:756-763
35. Rahman MU, Kleyman TR, McEntee CM, Hudson AP (1994) Regulation of mitochondrial cAMP-dependent protein kinase activity in yeast. Biochem Mol Biol Int 34:745-753
36. Ray DB, Butow RA (1979a) Regulation of mitochondrial ribosomal RNA synthesis in yeast. I. In search of a relaxation of stringency. Mol Gen Genet 173:227-238
37. Ray DB, Butow RA (1979b) Regulation of mitochondrial ribosomal RNA synthesis in yeast. II. Effects of temperature-sensitive mutants defective in cytoplasmic protein synthesis. Mol Gen Genet 173:239-247
38. Roesler WJ, Vandenbark GR, Hanson RW (1988) Cyclic AMP and the induction of eukaryotic transcription. J Biol Chem 263:9063-9066
39. Sambrook J, Fritsch EF, Maniatis T (1989) Molecular cloning: a laboratory manual (2nd edn.) Cold Spring Harbor Laboratory, Cold Spring Harbor, New York
40. Schinkel AH, Groot Koerkamp MJA, Touw EPW, Tabak HF (1986) Characterization of the promoter of the large ribosomal RNA gene in yeast mitochondria and separation of mitochondrial RNA polymerase activity into two different components. EMBO J 5:1041-1047
41. Shadel GS, Clayton DA (1993) Mitochondrial transcriptional initiation. J Biol Chem 268:16083-16086
42. Shadel GS, Clayton DA (1995) A Saccharomyces cerevisiae transcription factor. sc-mtTFB, shares features with sigma factors but is functionally distinct. Mol Cell Biol 15:2101-2108
43. Sherman F, Fink GR, Hicks JB (1983) Methods in yeast genetics. Cold Spring Harbor Laboratory, Cold Spring Harbor, New York
44. Struhl K (1989) Molecular mechanisms of transcriptional regulation in yeast. Annu Rev Biochem 58:1051-1077
45. Suzuki H, Hosokawa Y, Toda H, Nishikimi M, OzawaT (1990) Common protein binding sites in the 5′-flanking regions of human genes for cytochrome cl and ubiquinone-binding protein. J Biol Chem 265:8159-8163
46. Suzuki H, Hosokawa Y, Toda H, Nishikimi M, Ozawa T (1991) Existence of common homologous elements in the transcriptional regulatory regions of human nuclear genes and mitochondrial genes for the oxidative phosphorylation system. J Biol Chem 266:2333-2338
47. Toda T, Cameron S, Sass P, Zoller M, Scott JD, McMullen B, Hurwitz M, Krebs EG, Wigler M (1987) Cloning and characterization of BCY1, a locus encoding a regulatory subunit of the cAMP-dependent protein kinase in Saccharomyces cerevisiae. Mol Cell Biol 7:1371-1377
48. Tracy RL, Stern DB (1995) Mitochondrial transcriptional initiation: promoter structures and RNA polymerases. Curr Genet 28:205-216
49. Ulery TL, Jang SH, Jaehning JA (1994) Glucose repression of yeast mitochondrial transcription: kinetics of derepression and role of nuclear genes. Mol Cell Biol 14:1160-1170
50. Wettstein-Edwards J, Ticho BS, Martin NC, Najarian D, Getz G (1986) In vitro transcription and promoter strength analysis of five mitochondrial tRNA promoters in yeast. J Biol Chem 261: 2905-2911
51. Winde JH de, Grivell LA (1993) Global regulation of mitochondrial biogenesis in Saccharomyces cerevisiae. Prog Nucleic Acids Res Mol Biol 46:51-91
52. Winkley CS, Keller MJ, Jaehning JA (1985) A multi-component mitochondrial RNA polymerase from Saccharomyces cerevisiae. J Biol Chem 260:14214-14223
53. Zamaroczy M de, Bernardi G (1986) The primary structure of the mitochondrial genome of Saccharomyces cerevisiae - a review. Gene 47:155-177
54. Zennaro E, Grimaldi L, Baldacci G, Frontali L (1985) Mitochondrial transcription and processing of transcripts during release from glucose repression in "resting cells" of Saccharomyces cerevisiae. Eur J Biochem 147:191-196