Pathogenesis of abdominal aortic aneurysms - Cellular and biochemical mechanisms

European Journal of Vascular and Endovascular Surgery

Volumn 12, Issue 4, 1996, Pages 391-400

  Wills, A ^a   Thompson, M M ^a   Crowther, M ^a   Sayers, R D ^a   Bell, P R F ^a  

^a LEICESTER ROYAL INFIRMARY   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ABDOMINAL AORTA; ABDOMINAL AORTA ANEURYSM; AORTA ATHEROSCLEROSIS; AORTA WALL; CONGENITAL DISORDER; EXTRACELLULAR MATRIX; GENETIC SUSCEPTIBILITY; HEMODYNAMICS; HISTOLOGY; HUMAN; INFLAMMATION; INFLAMMATORY INFILTRATE; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN DEGRADATION; REVIEW;

EID: 0030448875     PISSN: 10785884     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1078-5884(96)80002-5     Document Type: Review

References (111)

1. Collin J Araujo L Walton J Lindsell D Oxford screening programme for abdominal aortic aneurysm in men aged 65 to 75 years Lancet ii 1988 613 615
2. Lucarotti M Shaw E Poskitt K Heather B The Gloucestershire Aneurysm Screening Programme: the first 2 years' experience Eur J Vasc Surg 7 1993 397 401
3. Bengtsson H Nilsson P Bergqvist D Natural history of abdominal aortic aneurysm detected by screening Br J Surg 80 1993 718 720
4. The UK Small Aneurysm Trial Participants The UK small aneurysm trial: design, methods and progress Eur J Vasc Surg 9 1995 42 48
5. Gadowski GR Pilcher DB Ricci MA Abdominal aortic aneurysm expansion rate: effect of size and beta-adrenergic blockade J Vasc Surg 19 1994 727 731
6. Baxter BT McGee GS Shively VP Elastin content, cross links and mRNA in normal and aneurysmal human aorta J Vasc Surg 16 1992 192 200
7. Galis Z Muszynski M Sukhova G Cytokine-stimulated human vascular smooth muscle cells synthesize a complement of enzymes required for extracellular matrix digestion Circ Res 75 1994 181 189
8. Wolinsky H Glagov S A lamellar unit of aortic medial structure and function in mammals Circ Res 20 1967 99 111
9. Koch AE Haines GK Pearce WH Human abdominal aortic aneurysms: Immunophenotypic analysis suggesting an immune-mediated response Am J Pathol 137 1990 1199 1215
10. Baxter BT Davis VA Minion DJ Wang YP Lynch TG McManus BM Abdominal aortic aneurysms are associated with altered matrix proteins of the nonaneurysmal aortic segments J Vasc Surg 19 1994 797 802
11. Gargiulo M Stella A Spina M Content and turnover of extracellular matrix protein in human “nonspecific” and inflammatory abdominal aortic aneurysms Eur J Vasc Surg 7 1993 546 553
12. Minion DJ Davis VA Nejezchleb PA Wang Y McManus BM Baxter BT Elastin is increased in abdominal aortic aneurysms J Surg Res 57 1994 443 446
13. Sumner DS Hokanson DE Strandness DE Stress-strain characteristics and collagen-elastin content of abdominal aortic aneurysms Surg Gynecol Obstet 1970 459 466
14. Powell J Greenhalgh RM Cellular, enzymatic, and genetic factors in the pathogenesis of abdominal aortic aneurysms J Vasc Surg 9 1989 297 304
15. Campa JS Greenhalgh RM Powell JT Elastic degradation in abdominal aortic aneurysms Atherosclerosis 65 1987 13 21
16. Gandhi RH Irizarry E Cantor JO Analysis of elastin cross-linking and the connective tissue matrix of abdominal aortic aneurysms Surgery 115 1994 617 620
17. Sakalihasan N Heyeres A Nusgens BV Limet R Lapiere CM Modifications of the extracellular matrix of aneurysmal abdominal aortas as a function of their size Eur J Vasc Surg 7 1993 633 637
18. Mennshi S Campa JS Greenhalgh RM Powell JT Collagen in abdominal aortic aneurysm: typing, content and degradation J Vasc Surg 6 1987 578 582
19. White JV Haas K Phillips S Comerota AJ Adventitial elastolysis is a primary event in aneurysm formation J Vasc Surg 17 1993 371 380
20. Leung D Glagov S Mathews M Cyclic stretching stimulates synthesis of matrix comonents by arterial smooth muscle cells in vitro Science 191 1976 475 477
21. Mcgee GS Baxter BT Shively VP Aneurysm or occlusive disease-factors determining the clinical course of atherosclerosis of the infrarenal aorta Surgery 110 1991 370 375
22. Mesh CL Baxter BT Pearce WH Chisholm RL McGee GS Yao JST Collagen and elastin gene expression in aortic aneurysms Surgery 112 1992 265 272
23. Ward AS Aortic aneurysmal disease: a generalised dilating diathesis Arch Surg 127 1992 990 991
24. Ramirez F Periera L Zhang H Lee B The fibrillin-Marfan syndrome connection Bioessays 15 1993 589 594
25. Superti-Furga A Steinmann B Ramirez F Byers P Molecular defects of type III procollagen in Ehlers-Danlos syndrome type IV Hum Genet 82 1989 104 108
26. Clifton M Familial abdominal aortic aneurysms Br J Surg 64 1977 765 766
27. Majumber PP St. Jean PL Ferrell RE Webster MW Steed DL On the inheritance of abdominal aortic aneurysm Am J Hum Genet 48 1991 164 170
28. Verloes A Sakalihasan N Koulischer L Limet R Aneurysms of the abdominal aorta: familial and genetic aspects of three hundred thirteen pedigrees J Vasc Surg 21 1995 646 655
29. Cohen JR Sarfati I Ratner L Tilson D Alphal-antitrypsin phenotypes in patients with abdominal aortic aneurysms J Surg Res 49 1990 319 321
30. Ccronenwett J Murphy T Zelenock G Actuarial analysis of variables associated with rupture of small abdominal aortic aneurysms Surgery 98 1985 472 483
31. Ramsbottom D Fitzgerald P Grace PA Biochemical and molecular genetic studies of abdominal aortic aneurysm in an Irish population Eur J Vasc Surg 8 1994 716 722
32. Elzouki ANY Eriksson S Abdominal aortic aneurysms and alpha 1 — antitrypsin defficiency J Int Med 236 1994 587 591
33. Pope F Nicholls A Narcisi P Bartlett J Neil-Dwyer G Doshi B Some patients with cerebral aneurysms are deficient in type III collagen Lancet 1 1981 973 980
34. Kontusaari S Tromp G Kuivaniemi H Romanic AM Prockop DJ A mutation in the gene for type III procollagen (COL3A1) in a family with aortic aneurysms J Clin Invest 86 1990 1465 1473
35. Powell JT Adamson J MacSweeney ST Greenhalgh RM Humphries SE Henney AM Influence of type III collagen genotype on aortic diameter and disease Br J Surg 80 1993 1246 1248
36. Tromp G Wu Y Prockop DJ Sequencing of cDNA from 50 unrelated patients reveals that mutations in the triple helical domain of Type III procollagen are an infrequent cause of abdominal aneurysms J Clin Invest 91 1993 2539 2545
37. Verloes A Sakalishasan N Limet R Aneurysms of the abdominal aorta: familial and genetic aspects in three hundred thirteen pedigrees J Vasc Surg 21 1995 646 655
38. Sonesson B Lanne T Vernersson E Hansen F Sex differences in the mechanical properties of the abdominal aorta in human beings J Vasc Surg 20 1994 959 969
39. MacSweeney STR Powell JT Greenhalgh RM Pathogenesis of abdominal aortic aneurysm Br J Surg 81 1994 935 941
40. McDonald DA Regional pulse wave velocity in the arterial tree J Appl Physiol 24 1968 73 78
41. Vollmar J Paes E Pauschinger P Henze E Friesch A Aortic aneurysms as late sequelae of above-knee amputation Lancet ii 1989 834 835
42. (in press) Oyre S Pedersen EM Ringgaard S Boesiger P Paaske WP Quantification of in vivo wall shear stress by magnetic resonance: development, evaluation and application with regards to the normal human abdominal aorta Eur J Vasc Endovasc Surg 1996
43. Bluth EI Murphey SM Hollier LH Sullivan MA Colour flow doppler in the evaluation of aortic aneurysms Int Angiol 9 1990 8 10
44. Peattie RA Schrader T Bluth EI Comstock CE Development of turbulence in steady flow through models of abdominal aortic aneurysms J Ultrasound Med 13 1994 467 472
45. Schrader T Peattie RA Bluth EI Comstock CE A qualitative investigation of turbulence in flow through a model abdominal aortic aneurysm Invest Radiol 27 1992 515 519
46. Scherer PW Flow in axisymmetric glass model aneurysms J Biomech 6 1973 695 700
47. Sugimoto N Uyama C Sugahara T Yanagihara Y Estimation of 2-D blood flow velocity map from cine-angiograms: algorithm using overlapping block set and illustration of vortex flow in abdominal aneurysm Med Biol Eng Comput 32 1994 S178 S184
48. Low M Perktold K Raunig R Hemodynamics in rigid and distensible saccular aneurysms: a numerical study of pulsatile flow characteristics Biorheology 30 1993 287 298
49. Laustsen J Paaske WP Oyre S Pedersen EM Dynamic quantification, visualisation and animation of blood velocities and flows in infrarenal aortic aneurysms in vivo by three dimensional MR phase velocity encoding Eur J Vasc Endovasc Surg 9 1995 383 388
50. Asbury CL Ruberti JW Bluth EI Peattie RA Experimental investigation of steady flow in rigid models of abdominal aortic aneurysms Ann Biomed Eng 23 1995 29 39
51. Woessner J Matrix metalloproteinases and their inhibitors in connective tissue remodelling FASEB J 5 1991 2145 2154
52. Herron GS Unemori E Wong M Rapp JH Hibbs MH Stoney RJ Connective tissue proteinases and inhibitors in abdominal aortic aneurysms. Involvement of the vasa vasorum in the pathogenesis of aortic aneurysms Arterioscler Thromb 11 1991 1667 1677
53. Dubick M Hunter G Perez-Lizano E Mar G Geokas M Assessment of the role of pancreatic proteases in human abdominal aortic aneurysms and occlusive disease Clin Chim Acta 177 1988 1 10
54. Busuttil R Rinderbriecht H Flesher A Carmack C Elastase activity: the role of elastase in aortic aneurysm formation J Surg Res 32 1982 214 217
55. Busuttil RW Abou-Zamzam AM Machleder HI Collagenase activity of the human aorta. A comparison of patients with and without abdominal aortic aneurysms Arch Surg 115 1980 1373 1378
56. Vine N Powell JT Metalloproteinases in degenerative aortic disease Clin Sci (Colch) 81 1991 233 239
57. Newman K Ogata Y Malon A Identification of matrix metalloproteinase-3 (stromelysin-1) and 9 (gelatinase-B) in abdominal aortic aneurysms Arterioscler Thromb 14 1994 1315 1320
58. Newman K Malon A Shin R Scholes J Ramey W Tilson M Matrix metalloproteinases in abdominal aortic aneurysm: characterisation, purification, and their possible sources Connective Tissue Res 30 1994 265 276
59. Cannon DJ Read RC Blood elastolytic activity in patients with aortic aneurysm Ann Thorac Surg 34 1982 101 105
60. Cohen JR Mandell C Wise L Characterisation of human aortic elastase found in patients with abdominal aortic aneurysms Surg Gynecol Obstet 165 1987 301 304
61. Anidjar S Salzmann JL Gentric D Lagneau P Camilleri JP Michel JB Elastase-induced experimental aneurysms in rats Circulation 82 1990 973 981
62. Halpern VJ Nackman GB Gandhi RH The elastase infusion model of experimental aortic aneurysms: synchrony of induction of endogenous proteinases with matrix destruction and inflammatory cell response J Vasc Surg 20 1994 51 60
63. Brown S Backstrom B Busuttil F A new serum proteolytic enzyme in aneurysm pathogenesis J Vasc Surg 2 1985 393 399
64. Brophy CM Sumpio B Reilly JM Tilson MD Electrophoretic characterisation of protease expression in aneurysmal aorta: report of a unique 80kDa elastolytic activity Surg Res Comm 10 1991 315 321
65. Senior R Griffin G Fliszar C Shapiro S Goldberg G Welgus H Human 92- and 72-kilodalton Type IV collagenases are elastases J Biol Chem 266 1991 7870 7875
66. Irizarry E Newman KM Gandhi RH Demonstration of interstitial collagenase in abdominal aortic aneurysm disease J Surg Res 54 1993 571 574
67. Webster MW McAuley CE Steed DL Miller DD Evans CH Collagen stability and collagenolytic activity in the normal and aneurysmal human abdominal aorta Am J Surg 161 1991 635 638
68. Tilson M Newman K Proteolytic mechanisms in the pathogenesis of aortic aneurysm Yao J Pearce W Aneurysms: New findings and treatment 1995 Appleton and Lange Connecticut 3 10
69. Okada Y Nagase H Harris E A metalloproteinase from human rheumatoid synovial fibroblasts that digests connective tissue matrix components J Biol Chem 261 1986 14245 14255
70. Suzuki K Enghild J Morodomi T Salvesen G Nagase H Mechanisms of activation of tissue procollagenase by matrix metalloproteinase 3 (stromelysin) Biochemistry 29 1990 10261 10270
71. Freestone T Turner RJ Coady A Higman DJ Greenhalgh RM Powell JT Inflammation and matrix metalloproteinases in the enlarging abdominal aortic aneurysm Arterioscer Thromb Vasc Biol 15 1995 1145 1151
72. Brophy CM Marks WH Reilly JM Tilson MD Decreased tissue inhibitor of metalloproteinases (TIMP) in abdominal aortic aneurysm tissue: a preliminary report J Surg Res 50 1991 653 657
73. Tilson MD Reilly JM Brophy CM Wwbster EL Barnett TR Expression and sequence of the gene for tissue inhibitor of metalloproteinases in patients with abdominal aortic aneurysms J Vasc Surg 18 1993 266 270
74. Jean-Claude J Newman K Li H Gregory A Tilson M Possible key role for plasmin in the pathogenesis of abdominal aortic aneurysms Surgery 116 1994 472 478
75. Reilly JM Sicard GA Lucore CL Abnormal expression of plasminogen activators in aortic aneurysmal and occlusive disease J Vasc Surg 19 1994 865 872
76. He C Wilhelm S Pentland A Tissue co-operation in a proteolytic cascade activating human interstitial collagenase Proc Natl Acad Sci USA 86 1989 2632 2636
77. Katsuda S Okada Y Imai K Nakanishi I Matrix metalloproteinase-9 (92-kd gelatinase) can degrade arterial elastin Am J Path 145 1994 1208 1218
78. Brophy CM Reilly JM Smith GJ Tilson MD The role of inflammation in nonspecific abdominal aortic aneurysm disease Ann Vasc Surg 5 1991 229 233
79. Beckman EN Plasma cell infiltrates in atherosclerotic abdominal aortic aneurysms Am J Clin Pathol 85 1986 21 24
80. Shapiro S Campbell E Senior R Welgus H Proteinases secreted by human mononuclear phagocytes J Rheumatol 18 Suppl. 27 1991 95 98
81. Newman KM Jean-Claude J Li H Cellular localisation of matrix metalloproteinases in the abdominal aortic aneurysm wall J Vasc Surg 20 1994 814 820
82. [Part 2] Newman K Jean-Claude J Lii H Ramey W Tilson M Cytokines that activate proteolysis are increased in abdominal aortic aneurysms Circulation 90 1994 II
83. Szekanecz Z Shah M Pearce W Koch A Human atherosclerotic abdominal aortic aneurysms produce interleukin (IL)-6 and interferon-gamma but not IL-2 and IL-4: The possible role of IL-6 and interferon-gamma in vascular inflammation Agents and Actions 42 1994 159 162
84. Koch AE Kunkel SL Pearce WH Enhanced production of the chemotactic cytokines interleukin-8 and monocyte chemoattractant protein-1 in human abdominal aortic aneurysms Am J Pathol 142 1993 1423 1431
85. Moyer C Sajuthi D Tulli H Williams J Synthesis of IL-1alpha and IL-1beta by arterial cells in atheroaclerosis Am J Path 138 1991 951 960
86. Pearce WH Sweis I Yao JS McCarthy WJ Koch AE Interleukin-1 beta and tumor necrosis factor-alpha release in normal and diseased human infrarenal aortas J Vasc Surg 16 1992 784 789
87. Libby P Warner S Friedman G IL-1: a mitogen for human vascular smooth muscle cells that induces the release of growth-inhibitory prostanoids J Clin Invest 81 1988 487 498
88. Elias J Freundlich B Adams S Rosenbloom J Regulation of human lung fibroblast collagen production by recombinant interleukin-1, tumour necrosis factor, and interferon gamma Ann NY Acad Sci 580 1990 233 244
89. Rock C Lowry S Tumour necrosis factor-alpha J Surg Res 51 1991 434 445
90. Warner S Libby P Human vascular smooth muscle cells. Target for and source of tumour necrosis factor J Immunol 142 1989 100 109
91. Szekanecz Z Shah MR Harlow LA Pearce WH Koch AE Interleukin-8 and tumour necrosis factor alpha are involved in human aortic endothelial cell migration Pathobiology 62 1994 134 139
92. Holmes DR Liao S Parkes WC Thompson RW Medial neovascularisation in abdominal aortic aneurysms: A histopathological marker of aneurysmal degeneration with pathophysiological implications J Vasc Surg 21 1995 761 772
93. Mignatti P Tsuboi R Rifkin DB In vitro angiogenesis on the human amniotic membrane: requirement for basic fibroblast growth factor-induced proteinases J Cell Biol 108 1989 671 682
94. Pober J What can be learned from the expression of endothelial adhesion molecules in tissue? Lab Invest 64 1991 301 305
95. Davis CA Pearce WH Haines GK Shah M Koch AE Increased ICAM-1 expression in aortic disease J Vasc Surg 18 1993 875 880
96. Loppnow H Libby P Proliferating or interleukin-1 activated human vascular smooth muscle cells secrete copious interleukin-6 J Clin Invest 85 1990 731 738
97. Cid M Campo E Erilla G Immunohistochemical analysis of lymphoid and macrophage cell subsets and their immunologic activation markers in temporal arteritis Arthritis Rheum 32 1989 884 893
98. Cohen JR Sarfati I Danna D Wise L Smooth muscle cell elastase, atherosclerosis, and abdominal aortic aneurysms Ann Surg 216 1992 327 330
99. Cohen JR Keegan L Sarfati I Danna D Ilardi C Wise L Neutrophil chemotaxis and neutrophil elastase in the aortic wall in patients with abdominal aortic aneurysms J Invest Surg 4 1991 423 430
100. Mauviel A Cytokine regulation of metalloproteinase gene expression J Cell Biol 53 1993 288 295
101. Keen R Nolan K Cipollone M Interleukin-1beta induces differential gene expression in aortic smooth muscle cells J Vasc Surg 20 1994 774 786
102. Welgus H Campbell E Cury J Neutral metalloproteinases produced by human mononuclear phagocytes: enzyme profile, regulation, and expression during cellular development J Clin Invest 86 1990 1496 1502
103. Reed D Reed C Stemmermann G Hayashi T Are aortic aneurysms caused by atherosclerosis? Circulation 85 1992 205 211
104. Zarins C Glagov S Vesselinovitch D Wissler R Aneurysm formation in experimental atherosclerosis: relationship to plaque evolution J Vasc Surg 12 1990 246 256
105. Wolinsky H Glagov S Nature of species differences in the medial distribution of aortic vasa vasorum in mammals Circ Res 20 1967 409 421
106. Tilson M Atherosclerosis and aneurysm disease J Vasc Surg 12 1990 371 372
107. Tilson M Editorial comment: Aortic aneurysms and atherosclerosis Circulation 85 1992 205 211
108. Reilly J Tilson M Incidence and aetiology of abdominal aortic aneurysms Surg Clin North Am 69 1989 705 711
109. Glogov S Zarins C Giddens D Ku D Haemodynamics and atherosclerosis. Insights and perspectives gained from studies of human arteries Arch Pathol Lab Med 112 1988 1018 1031
110. Speziale F De Santis F Giannoni MF Familial incidence of abdominal aortic aneurysms Vasc Surg 28 1994 261 266
111. Darling R III Brewster D Darling R Are familial abdominal aortic aneurysms different? J Vasc Surg 10 1989 39 43