메뉴 건너뛰기




Volumn 795, Issue , 1996, Pages 202-207

An IL-12-based vaccine approach for preventing immunopathology in schistosomiasis

Author keywords

[No Author keywords available]

Indexed keywords

ANTIGEN; CD4 ANTIGEN; GAMMA INTERFERON; INTERLEUKIN 10; INTERLEUKIN 12; VACCINE;

EID: 0030448763     PISSN: 00778923     EISSN: None     Source Type: Book Series    
DOI: 10.1111/j.1749-6632.1996.tb52669.x     Document Type: Conference Paper
Times cited : (20)

References (22)
  • 1
    • 0027722239 scopus 로고
    • Schistosomiasis: Infection versus disease, hypersensitivity and immunity
    • CHEEVER, A. W. 1993. Schistosomiasis: Infection versus disease, hypersensitivity and immunity. Am. J. Pathol. 142: 699-709.
    • (1993) Am. J. Pathol. , vol.142 , pp. 699-709
    • Cheever, A.W.1
  • 2
    • 33847484835 scopus 로고
    • Granuloma formation around schistosome eggs as a manifestation of delayed hypersensitivity
    • WARREN, K. S., E. S. DOMINGO & R. B. T. COWAN. 1967. Granuloma formation around schistosome eggs as a manifestation of delayed hypersensitivity. Am. J. Pathol. 54: 1095-1102.
    • (1967) Am. J. Pathol. , vol.54 , pp. 1095-1102
    • Warren, K.S.1    Domingo, E.S.2    Cowan, R.B.T.3
  • 3
    • 0023269443 scopus 로고
    • Two types of murine helper cell clone. II. Delayed-type hypersensitivity is mediated by Thl clones
    • CHER, D. J. & T. R. MOSMANN. 1987. Two types of murine helper cell clone. II. Delayed-type hypersensitivity is mediated by Thl clones. J. Immunol. 138: 3688-3695.
    • (1987) J. Immunol. , vol.138 , pp. 3688-3695
    • Cher, D.J.1    Mosmann, T.R.2
  • 4
    • 0025924547 scopus 로고
    • Egg deposition is the major stimulus for the production of Th2 cytokines in murine schistosomiasis mansoni
    • GRZYCH, J. M., E. J. PEARCE, A. CHEEVER, Z. A. CAULADA, P. CASPAR, S. HEINY, F. LEWIS & A. SHER. 1991. Egg deposition is the major stimulus for the production of Th2 cytokines in murine schistosomiasis mansoni. J. Immunol. 146: 1322-1330.
    • (1991) J. Immunol. , vol.146 , pp. 1322-1330
    • Grzych, J.M.1    Pearce, E.J.2    Cheever, A.3    Caulada, Z.A.4    Caspar, P.5    Heiny, S.6    Lewis, F.7    Sher, A.8
  • 5
    • 0027260963 scopus 로고
    • Analysis of cytokine mRNA expression during primary granuloma formation induced by eggs of Schistosoma mansoni
    • WYNN, T. A., I. ELTOUM, A. W. CHEEVER, F. A. LEWIS, W. C. GAUSE & A. SHER. 1993. Analysis of cytokine mRNA expression during primary granuloma formation induced by eggs of Schistosoma mansoni. J. Immunol. 151: 1430-1438.
    • (1993) J. Immunol. , vol.151 , pp. 1430-1438
    • Wynn, T.A.1    Eltoum, I.2    Cheever, A.W.3    Lewis, F.A.4    Gause, W.C.5    Sher, A.6
  • 6
    • 0023726937 scopus 로고
    • Anti-proliferative effect of IFN-γ in immune regulation. I. IFN-γ inhibits the proliferation of Th2 but not Th1 murine helper T lymphocyte clones
    • GAJEWSKI, T. F. & F. W. FITCH. 1988. Anti-proliferative effect of IFN-γ in immune regulation. I. IFN-γ inhibits the proliferation of Th2 but not Th1 murine helper T lymphocyte clones. J. Immunol. 140: 4245-4252.
    • (1988) J. Immunol. , vol.140 , pp. 4245-4252
    • Gajewski, T.F.1    Fitch, F.W.2
  • 7
    • 0026056142 scopus 로고
    • IFN-γ modulates the early development of Th1 and Th2 responses in a murine model of cutaneous leishmaniasis
    • SCOTT, P. 1991. IFN-γ modulates the early development of Th1 and Th2 responses in a murine model of cutaneous leishmaniasis. J. Immunol. 147: 3149-3156.
    • (1991) J. Immunol. , vol.147 , pp. 3149-3156
    • Scott, P.1
  • 8
    • 0027255488 scopus 로고
    • + T cells subsets and induces early resistance to Leishmania major in mice
    • + T cells subsets and induces early resistance to Leishmania major in mice. J. Exp. Med. 178: 567-574.
    • (1993) J. Exp. Med. , vol.178 , pp. 567-574
    • Scharton, T.M.1    Scott, P.2
  • 10
    • 0025819340 scopus 로고
    • Induction of interferon γ production by natural killer cell stimulatory factor: Characterization of the responder cells and synergy with other inducers
    • CHAN, S. H., B. PERUSSIA, J. W GUPTA, M. KOBAYASHI, M. POSPISIL, H. A. YOUNG, S. F. WOLF, D. YOUNG, S. C. CLARK & G. TRINCHIERI. 1991. Induction of interferon γ production by natural killer cell stimulatory factor: Characterization of the responder cells and synergy with other inducers. J. Exp. Med. 173: 869-880.
    • (1991) J. Exp. Med. , vol.173 , pp. 869-880
    • Chan, S.H.1    Perussia, B.2    Gupta, J.W.3    Kobayashi, M.4    Pospisil, M.5    Young, H.A.6    Wolf, S.F.7    Young, D.8    Clark, S.C.9    Trinchieri, G.10
  • 12
    • 0027491655 scopus 로고
    • + T cells to enhance priming for IFN-γ production and diminishes IL-4 inhibition of such priming
    • + T cells to enhance priming for IFN-γ production and diminishes IL-4 inhibition of such priming. Proc. Natl. Acad. Sci. USA 90: 10188-10192.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 10188-10192
    • Seder, R.A.1    Gazzinelli, R.2    Sher, A.3    Paul, W.E.4
  • 13
    • 0026510075 scopus 로고
    • In vivo molecular analysis of lymphokines involved in the murine immune response during Schistosoma mansoni infection: II. Quantitation of IL-4 mRNA, IFN-γ mRNA, and IL-2 mRNA levels in the granulomatous livers, mesenteric lymph nodes, and spleens during the course of modulation
    • HENDERSON, G. S., X. Lu, T. L. MCCURLEY & D. G. COLLEY. 1992. In vivo molecular analysis of lymphokines involved in the murine immune response during Schistosoma mansoni infection: II. Quantitation of IL-4 mRNA, IFN-γ mRNA, and IL-2 mRNA levels in the granulomatous livers, mesenteric lymph nodes, and spleens during the course of modulation. J. Immunol. 148: 2261-2269.
    • (1992) J. Immunol. , vol.148 , pp. 2261-2269
    • Henderson, G.S.1    Lu, X.2    Mccurley, T.L.3    Colley, D.G.4
  • 15
    • 0028231754 scopus 로고
    • Endogenous interleukin-12 (IL-12) regulates granuloma formation induced by eggs of Schisiosoma mansoni and exogenous IL-12 both inhibits and prophylactically immunizes against egg pathology
    • WYNN, T. A., I. ELTOUM, I. P. OSWALD, A. W. CHEEVER & A. SHER. 1994. Endogenous interleukin-12 (IL-12) regulates granuloma formation induced by eggs of Schisiosoma mansoni and exogenous IL-12 both inhibits and prophylactically immunizes against egg pathology. J. Exp. Med. 179: 1551-1561.
    • (1994) J. Exp. Med. , vol.179 , pp. 1551-1561
    • Wynn, T.A.1    Eltoum, I.2    Oswald, I.P.3    Cheever, A.W.4    Sher, A.5
  • 16
    • 14844344682 scopus 로고
    • IL-12 exacerbates rather than suppresses T helper 2-dependent pathology in the absence of endogenous IFN-γ
    • WYNN, T. A., D. JANKOVIC, S. HIENY, K. ZIONCHECK, P. JARDIEU, A. W. CHEEVER & A. SHER. 1995. IL-12 exacerbates rather than suppresses T helper 2-dependent pathology in the absence of endogenous IFN-γ. J. Immunol. 154: 3999-4009.
    • (1995) J. Immunol. , vol.154 , pp. 3999-4009
    • Wynn, T.A.1    Jankovic, D.2    Hieny, S.3    Zioncheck, K.4    Jardieu, P.5    Cheever, A.W.6    Sher, A.7
  • 17
    • 0028069831 scopus 로고
    • IL-12 inhibits Th2 cytokine responses induced by eggs of Schistosoma mansoni
    • OSWALD, I. P., P. CASPAR, D. JANKOVIC, T. A. WYNN, E. J. PEARCE & A. SHER. 1994. IL-12 inhibits Th2 cytokine responses induced by eggs of Schistosoma mansoni. J. Immunol. 153: 1707-1713.
    • (1994) J. Immunol. , vol.153 , pp. 1707-1713
    • Oswald, I.P.1    Caspar, P.2    Jankovic, D.3    Wynn, T.A.4    Pearce, E.J.5    Sher, A.6
  • 18
    • 0029142790 scopus 로고
    • An IL-12-based vaccination method for preventing fibrosis induced by schistosome infection
    • WYNN, T. A., A. W. CHEEVER, D. JANKOVIC, R. W. POINDEXTER, P. CASPAR, F. A. LEWIS & A. SHER. 1995. An IL-12-based vaccination method for preventing fibrosis induced by schistosome infection. Nature 376: 594-597.
    • (1995) Nature , vol.376 , pp. 594-597
    • Wynn, T.A.1    Cheever, A.W.2    Jankovic, D.3    Poindexter, R.W.4    Caspar, P.5    Lewis, F.A.6    Sher, A.7
  • 19
    • 0024730940 scopus 로고
    • Macrophage production of transforming growth factor β and fibroblast collagen synthesis in chronic pulmonary inflammation
    • KHALIL, N., O. BEREZNAY, M. SPORN & A. H. GREENBERG. 1989. Macrophage production of transforming growth factor β and fibroblast collagen synthesis in chronic pulmonary inflammation. J. Exp. Med. 170: 727-737.
    • (1989) J. Exp. Med. , vol.170 , pp. 727-737
    • Khalil, N.1    Bereznay, O.2    Sporn, M.3    Greenberg, A.H.4
  • 21
    • 0029042649 scopus 로고
    • IL-12 enhances vaccine-induced immunity to Schistosoma mansoni in mice and decreases T helper 2 cytokine expression, IgE production, and tissue eosinophilia
    • WYNN, T. A., D. JANKOVIC, S. HIENY, A. W. CHEEVER & A. SHER. 1995. IL-12 enhances vaccine-induced immunity to Schistosoma mansoni in mice and decreases T helper 2 cytokine expression, IgE production, and tissue eosinophilia. J. Immunol. 154: 4701-4709.
    • (1995) J. Immunol. , vol.154 , pp. 4701-4709
    • Wynn, T.A.1    Jankovic, D.2    Hieny, S.3    Cheever, A.W.4    Sher, A.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.