Optical resolution of pantolactone by a novel fungal enzyme, lactonohydrolase

Annals of the New York Academy of Sciences

Volumn 799, Issue , 1996, Pages 650-658

  Shimizu, Sakayu ^a   Kataoka, Michihiko ^a  

^a KYOTO UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ENZYME; HYDROLASE; LACTONOHYDROLASE; PANTOLACTONE; UNCLASSIFIED DRUG;

CARBOHYDRATE ANALYSIS; CONFERENCE PAPER; CONTROLLED STUDY; DRUG HYDROLYSIS; ENZYME SPECIFICITY; FUNGUS; OPTICAL RESOLUTION; PH; STEREOCHEMISTRY;

EID: 0030448757     PISSN: 00778923     EISSN: None     Source Type: Book Series    
DOI: 10.1111/j.1749-6632.1996.tb33270.x     Document Type: Conference Paper

References (15)

1. HATA, H., S. SHIMIZU & H. YAMADA. 1987. Enzymatic production of D-(-)-pantoyl lactone from ketopantoyl lactone. Agric. Biol. Chem. 51: 3011-3016.
2. SHIMIZU, S., H. HATA & H. YAMADA. 1984. Reduction of ketopantoyl lactone to D-(-)-pantoyl lactone by microorganisms. Agric. Biol. Chem. 48: 2285-2291.
3. SHIMIZU, S., H. YAMADA, H. HATA, T. MORISHITA, S. AKUTSU & M. KAWAMURA. 1987. Novel chemoenzymatic synthesis of D-(-)-pantoyl lactone. Agric. Biol. Chem. 51: 289-290.
4. KATAOKA, M., S. SHIMIZU & H. YAMADA. 1990. Novel enzymatic production of D-(-)-pantoyl lactone through the stereospecific reduction of ketopantoic acid. Agric. Biol. Chem. 54: 177-182.
5. KATAOKA, M., S. SHIMIZU, Y. DOI, K. SAKAMOTO & H. YAMADA. 1990. Stereospecific reduction of ethyl 2′-ketopantothenate to ethyl D-(+)-pantothenate with microbial cells as a catalyst. Appl. Environ. Microbiol. 56: 3595-3597.
6. KATAOKA, M., S. SHIMIZU, Y. DOI, K. SAKAMOTO & H. YAMADA. 1990. Microbial production of chiral pantothenonitrile through stereospecific reduction of 2′-ketopantothenonitrile. Biotechnol. Lett. 12: 357-360.
7. SHIMIZU, S., S. HATTORI, H. HATA & H. YAMADA. 1987. One-step microbial conversion of a racemic mixture of pantoyl lactone to optically active D-(-)-pantoyl lactone. Appl. Environ. Microbiol. 53: 519-522.
8. SHIMIZU, S., S. HATTORI, H. HATA & H. YAMADA. 1987. Stereoselective enzymatic oxidation and reduction system for the production of D-(-)-pantoyl lactone from a racemic mixture of pantoyl lactone. Enzyme Microb. Technol. 9: 411-416.
9. KATAOKA, M., S. SHIMIZU & H. YAMADA. 1991. Stereospecific conversion of a racemic pantoyl lactone to D-(-)-pantoyl lactone through microbial oxidation and reduction reactions. Reel. Trav. Chim. Pays-Bas Belg. 110: 155-157.
10. GLANZER, B. I., K. FABER & H. GRIENGL. 1988. Microbial resolution of O-acetyl pantoyl lactone. Enzyme Microb. Technol. 10: 689-690.
11. BEVINAKATTI, H. S. & R. V. NEWADKAR. 1989. Lipase catalysis in organic solvents: transesterification of O-formyl esters of secondary alcohols. Biotechnol. Lett. 11: 785-788.
12. SHIMIZU, S., M. KATAOKA, K. SHIMIZU, M. HIRAKATA, K. SAKAMOTO & H. YAMADA. 1992. Purification and characterization of a novel lactonohydrolase, catalyzing the hydrolysis of aldonate lactones and aromatic lactones, from Fusarium oxyspomm. Eur. J. Biochem. 209: 383-390.
13. KATAOKA, M., K. SHIMIZU, K. SAKAMOTO, H. YAMADA & S. SHIMIZU. 1995. Optical resolution of racemic pantolactone with a novel fungal enzyme, lactonohydrolase. Appl. Microbiol. Biotechnol. 43: 974-977.
14. KATAOKA, M., K. SHIMIZU, K. SAKAMOTO, H. YAMADA & S. SHIMIZU. 1995. Lactonohydrolase-catalyzed optical resolution of pantoyl lactone: selection of a potent enzyme producer and optimization of culture and reaction conditions for practical resolution. Appl. Microbiol. Biotechnol. 44: 333-338.
15. KATAOKA, M., M. HIRAKATA, K. SAKAMOTO, H. YAMADA & S. SHIMIZU. 1996. Optical resolution of racemic pantoic acid through microbial Stereoselective lactonization in an inorganic solvent/water two-phase system. Enzyme Microb. Technol. 18: in press.