Relationship between lactate and ammonia thresholds in heart transplant patients

Chest

Volumn 110, Issue 3, 1996, Pages 693-697

  Chicharro, José L ^a   Vaquero, Almudena F ^a   Tello, Rocío ^a   Pérez, Margarita ^a   Lucía, Alejandro ^a  

^a UNIVERSIDAD COMPLUTENSE DE MADRID   (Spain)

Author keywords

ammonia; anaerobic threshold; cardiac transplantation; lactate threshold

Indexed keywords

AMMONIA; LACTIC ACID; OXYGEN;

ADULT; ARTICLE; BICYCLE ERGOMETRY; BLOOD LEVEL; CLINICAL ARTICLE; HEART RATE; HEART TRANSPLANTATION; HUMAN; LUNG GAS EXCHANGE; LUNG VENTILATION; MALE; OXYGEN CONSUMPTION; PRIORITY JOURNAL;

EID: 0030448719     PISSN: 00123692     EISSN: None     Source Type: Journal    
DOI: 10.1378/chest.110.3.693     Document Type: Article

References (38)

1. Keteyian S, Ehrman J, Fedel F, et al. Exercise following cardiac transplantation: recommendations for rehabilitation. Sports Med 1989; 8:251-59
2. Squires RW. Exercise training after cardiac transplantation. Med Sci Sports Exerc 1991; 23:686-94
3. Savin WM, Haskell WL, Schroeder JS, et al. Cardiorespiratory responses of cardiac transplant patients to graded, symptom-limited exercise. Circulation 1980; 62:55-60
4. Jansson E, Dudley GA, Norman B, et al. ATP and IMP in single human fibres after high intensity exercise. Clin Physiol 1987; 7:337-45
5. Katz A, Broberg S, Sahlin K, et al. Muscle ammonia and amino acid metabolism during dynamic exercise in man. Clin Physiol 1986; 6:365-79
6. Lowenstein JM. Ammonia production in muscle and other tissues: the purine nucleotide cycle. Physiol Rev 1972; 52:382-414
7. Stathis CG, Febbraio MA, Carey MF, et al. Influence of sprint training on human skeletal muscle purine nucleotide metabolism. J Appl Physiol 1994; 76:1802-09
8. Schlicht W, Naretz W, Witt D, et al. Ammonia and lactate: differential information on monitoring training load in sprint events. Int J Sports Med 1990; 11(suppl 2):S85-90
9. Babij P, Matthews SM, Rennie MJ. Changes in blood ammonia, lactate and amino acids in relation to workload during bicycle ergometer exercise in man. Eur J Appl Physiol 1983; 50:405-11
10. Buono MJ, Claney TR, Cook JR. Blood lactate and ammonium ion accumulation during graded exercise in humans. J Appl Physiol 1984; 57:135-39
11. Meyer RA, Terjung RL. AMP deamination and IMP reamination in working skeletal muscle. Am J Physiol 1980; 239:C32-38
12. Wilkerson JE, Batterton DL, Horvath SM. Exercise-induced changes in blood ammonia levels in humans. Eur J Appl Physiol 1977; 37:255-63
13. Karch SB, Billingham ME. Cyclosporine induced myocardial fibrosis: a unique controlled case report. Heart Transplant 1985; 4:210-12
14. Stovin PGI, English TAH. Effects of cyclosporine on the transplanted heart. Heart Transplant 1987; 6:180-85
15. American College of Sports Medicine. Guidelines for exercise testing and prescription. 4th ed. Philadelphia: Lea & Febiger, 1986; 95-6
16. Whipp BJ, Davis JA, Torres F, et al. A test to determine parameters of aerobic function during exercise. J Appl Physiol 1981; 50:217-21
17. Chicharro JL, Vaquero AF, Calvo F, et al. Determinación del umbral anaerobio en niños entrenados: protocolo en rampa en laboratorio vs test de campo. Med Sport 1993; 46:403-08
18. Brubaker PH, Berry MJ, Brozena SC, et al. Relationship of lactate and ventilatory thresholds in cardiac transplant patients. Med Sci Sports Exerc 1993; 25:191-96
19. Kavanagh T, Tocoub MH, Mertens DJ, et al. Cardiorespiratory responses to exercise training after orthotopic cardiac transplantation. Circulation 1988; 77:162-77
20. Cerretelli P, Grassi B, Colombini A, et al. Gas exchange and metabolic transients in heart transplant recipients. Respir Physiol 1988; 74:355-71
21. Sullivan MJ, Green HJ, Cobb FR. Altered skeletal muscle metabolic response to exercise in chronic heart failure: relation to skeletal muscle aerobic enzyme activity. Circulation 1991; 84: 1597-1607
22. Péronnet F, Morton RH. Plasma lactate concentration increases as a parabola with delay during ramp exercise. Eur J Appl Physiol 1994; 68:228-33
23. 2max, ventilatory and lactate thresholds in elderly women. Med Sci Sports Exerc 1986; 18:425-30
24. Meyer RA, Dudley GA, Terjung RL. Ammonia and IMP in different skeletal muscle fibers after exercise in rats. J Appl Physiol 1980; 49:1037-41
25. Mancini DM, Coyle E, Coggan A, et al. Contribution of intrinsic skeletal muscle changes to 31P NMR skeletal muscle metabolic abnormalities in patients with chronic heart failure. Circulation 1989; 80:1.338-46
26. Stratton JR, Kemp GJ, Daly RC, et al. Effects of cardiac transplantation on bioenergetic abnormalities of skeletal muscle in congestive heart failure. Circulation 1994; 89:1624-31
27. Massie BM, Conway M, Rajagopalan B, et al. Skeletal muscle metabolism during exercise under ischemic conditions in congestive heart failure: evidence for abnormalities unrelated to blood flow. Circulation 1988; 78:320-26
28. Arellano F, Krupp P. Muscular disorders associated with cyclosporin. Lancet 1991; 337:915
29. Goy J, Stauffer S, Deruaz J. Myopathy as a possible side effect of cyclosporin. Lancet 1989; 1:446-47
30. Adamopoulos S, Coats A, Brunotte F, et al. Physical training improves skeletal muscle metabolism in patients with chronic heart failure. J Am Coll Cardiol 1993; 21:1101-06
31. Bussieres-Chafe L, Pflugfelder P, Menkis A, et al. Basis for the aerobic impairment during exercise in patients late post cardiac transplantation. J Am Coll Cardiol 1993; 21:433A
32. Chance B, Williams GR. Respiratory enzymes in oxidative phosphorylation: the steady state. J Biol Chem 1955; 217:409-27
33. Diederich D, Yang Z, Luscher T. Chronic cyclosporin therapy impairs endothelium-dependent relaxation in the renal artery of the rat. J Am Soc Nephrol 1992; 2:1291-97
34. Stevenson L, Sietsma K, Tillisch J, et al. Exercise capacity for survivors of cardiac transplantation or sustained medical therapy for stable heart failure. Circulation 1990; 81:78-85
35. Taylor DC, Bore PJ, Styles P, et al. Bioenergeric of intact human muscle: a 31P nuclear magnetic resonance study. Mol Biol Med 1983; 1:77-94
36. Taylor DC, Styles P, Matthews PM, et al. Energetics of human muscle: exercise-induced ATP depletion. Magn Reson Med 1986; 3:44-54
37. Sewell DA, Gleeson M, Blannin AK. Hyperammonaemia in relation to high-intensity exercise duration in man. Eur J Appl Physiol 1994; 69:350-54
38. Dudley GA, Staron RS, Murray TF, et al. Muscle fiber composition and blood ammonia levels after intense exercise in humans. J Appl Physiol 1983; 54:582-86