Effects of glutamate and aspartate on myocardial substrate oxidation during potassium arrest

Journal of Thoracic and Cardiovascular Surgery

Volumn 112, Issue 6, 1996, Pages 1651-1660

  Reed, M K ^a   Barak, C ^a   Malloy, C R ^a   Maniscalco, S P ^a   Jessen, M E ^a   Buckberg, G D ^a  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ASPARTIC ACID; GLUTAMIC ACID; POTASSIUM;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CARDIOPLEGIA; CITRIC ACID CYCLE; CONTROLLED STUDY; HEART ARREST; HEART MUSCLE METABOLISM; HEART MUSCLE OXYGEN CONSUMPTION; HEART MUSCLE PERFUSION; MALE; NONHUMAN; OXIDATION; PRIORITY JOURNAL; RAT;

EID: 0030448394     PISSN: 00225223     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0022-5223(96)70024-7     Document Type: Article

References (30)

1. YS Choong JB Gavin LC. Armiger Effects of glutamic acid on cardiac function and energy metabolism of rat heart during ischaemia and reperfusion J Mol Cell Cardiol 20 1988 1043 1051
2. CD Snaith G Wright M. Lofkin The effects of aspartate and 2-oxoglutarate upon glycolytic energy metabolites and mechanical recovery following global ischemia in isolated rat hearts J Mol Cell Cardiol 24 1992 305 315
3. OI Pisarenko FL Rosenfeldt L Langley RAJ Conyers SM. Richards Differing protection with aspartate and glutamate cardioplegia in the isolated rat heart Ann Thorac Surg 59 1995 1541 1548
4. CK Haan HL Lazar S Rivers C Coady RJ. Shemin Improved myocardial preservation during cold storage using substrate enhancement Ann Thorac Surg 50 1990 80 85
5. JA Bittl KI. Shine Protection of ischemic rabbit myocardium by glutamic acid Am J Physiol 245 1983 H406 H412
6. ER Rosenkranz F Okamoto GD Buckberg JM Robertson J Vinten-Johansen H. Bugyi Safety of prolonged aortic clamping with blood cardioplegia. III. Aspartate enrichment of glutamate-blood cardioplegia in energy-depleted hearts after ischemic and reperfusion injury J THORAC CARDIOVASC SURG 91 1986 428 435
7. PL Julia ER Kofsky GD Buckberg HH Young HI. Bugyi Studies of myocardial protection in the immature heart. I. Enhanced tolerance of immature versus adult myocardium to global ischemia with reference to metabolic differences J THORAC CARDIOVASC SURG 100 1990 879 887
8. LR Bush S Warren CL Mesh BR. Lucchesi Comparative effects of aspartate and glutamate during myocardial ischemia Pharmacology (Basel) 23 1981 297 304
9. RM Engelman WA Dobbs JH Rousou MK. Meeran Myocardial high energy phosphate replenishment during ischemic arrest: aerobic vs. anaerobic metabolism Ann Thorac Surg 33 1982 453 458
10. BS Allen GD Buckberg FM Fontan MM Kirsh G Popoff F Beyersdorff Superiority of controlled surgical reperfusion versus percutaneous transluminal coronary angioplasty in acute coronary occlusion J THORAC CARDIOVASC SURG 105 1993 864 884
11. F Beyersdorf M Kirsh GD Buckberg BS. Allen Warm glutamate/aspartate enriched blood cardioplegic solution for perioperative sudden death J THORAC CARDIOVASC SURG 104 1992 1141 1147
12. T Sanborn W Gavin S Berkowitz T Perille M. Lesch Augmented conversion of aspartate and glutamate to succinate during anoxia in rat heart Am J Physiol 273 1979 H535 H541
13. SF Bolling KF Childs XH. Ning Amino acid substrate preloading and postischemic myocardial recovery J Surg Res 53 1992 342 348
14. A Thomassen TT Nielsen JP Bagger P. Henningsen Effects of intravenous glutamate on substrate availability and utilization across the human heart and leg Metabolism 40 1991 378 384
15. ME Jessen TE Kovarik FM Jeffrey AD Sherry CJ Storey RY Chao Effects of amino acids on substrate selection, anaplerosis, and left ventricular function in the ischemic reperfused rat heart J Clin Invest 92 1993 831 839
16. C Remesy C. Demigne Changes in availability of glucogenic and ketogenic substrates and liver metabolism in fed or starved rats Ann Nutr Metab 27 1983 57 70
17. 13C NMR spectroscopy J Biol Chem 263 1988 6964 6971
18. 13C NMR under nonsteady-state conditions Biochemistry 29 1990 6756 6761
19. FM Jeffrey V Diczku AD Sherry CR. Malloy Substrate selection in the isolated working rat heart: effects of afterload, reperfusion, and concentration Basic Res Cardiol 90 1995 388 396
20. RG Weiss ST Gloth R Kalil-Filho VP Chacko MD Stern G. Gerstenblith Indexing tricarboxylic acid cycle flux in intact hearts by carbon-13 nuclear magnetic resonance Circ Res 70 1992 392 408
21. ED. Lewandowski Nuclear magnetic resonance evaluation of metabolic and respiratory support of work load in intact rabbit hearts Circ Res 70 1992 576 582
22. W. Stremmel Fatty acid uptake by isolated rat heart myocytes represents a carrier mediated transport process J Clin Invest 81 1988 844 852
23. RA Weisiger JG Fitz BF. Scharschmidt Hepatic oleate uptake. Electrochemical driving forces in intact rat liver J Clin Invest 83 1989 411 420
24. JG Robertson LL Barron MS. Olson Bovine heart pyruvate dehydrogenase kinase stimulation by monovalent ions J Biol Chem 264 1989 11626 11631
25. 11C Aspartic acid: enzymatic synthesis, myocardial uptake, and metabolism J Med Chem 25 1982 93 96
26. M Galiñanes DJ Chambers DJ. Hearse Effect of sodium aspartate on the recovery of the rat heart from long-term hypothermic storage J THORAC CARDIOVASC SURG 103 1992 521 531
27. GA Crooke LJ Harris EA Grossi FG Baumann R Esposito FC Spencer Role of amino acids and enhancement cardioplegia in routine myocardial protection: experimental results J THORAC CARDIOVASC SURG 106 1993 497 501
28. ER Rosenkranz GD Buckberg H Laks DG. Mulder Warm induction of cardioplegia with glutamate-enriched blood in coronary patients with cardiogenic shock who are dependent on inotropic drugs and intra-aortic balloon support J THORAC CARDIOVASC SURG 86 1983 507 518
29. LI Bonchek MW Burlingame BE Vazales NJ. Ferdinand Coronary bypass with substrate-enhanced cardioplegia versus non-cardioplegic technique for early revascularization in acute infarction Eur J Cardiothorac Surg 4 1990 124 129
30. H Brockerhoff RJ Hoyle N. Wolmark Positional distribution of fatty acids in triglycerides of animal depot fats Biochim Biophys Acta 116 1966 67 72