Sex determination by simultaneous application of polymerase chain reaction and fluorescent in situ hybridization on the same blastomere of a pre-embryo

Fertility and Sterility

Volumn 66, Issue 3, 1996, Pages 490-492

  Sasabe, Y ^a   Krisher, R L ^a   Stehlik, J C ^a   Stehlik, E F ^a   Katayama, K P ^a  

^a Advanced Institute of Fertility   (United States)

Author keywords

fluorescent in situ hybridization; human embryo; polymerase chain reaction; Preimplantation diagnosis; sex determination

Indexed keywords

ARTICLE; BLASTOMERE; CLINICAL ARTICLE; DIAGNOSTIC TEST; EMBRYO; FEMALE; FLUORESCENCE IN SITU HYBRIDIZATION; HUMAN; HUMAN CELL; MALE; POLYMERASE CHAIN REACTION; PREIMPLANTATION EMBRYO; PRIORITY JOURNAL; SEX DETERMINATION; X CHROMOSOME; Y CHROMOSOME;

EID: 0030448088     PISSN: 00150282     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0015-0282(16)58527-6     Document Type: Article

References (4)

1. A.H. Handyside J.D.A. Delhanty Cleavage stage biopsy of human embryos and diagnosis of X-linked recessive disease R.G. Edwards Preimplantation diagnosis of human genetic disease 1993 Cambridge University Press Cambridge 239 270
2. D.K. Griffin A.H. Handyside J.C. Harper L.J. Wilton G. Atkinson I. Soussis Clinical experience with preimplantation diagnosis of sex by dual fluorescent in situ hybridization J Assist Reprod Genet 11 1994 132 143
3. M. Witt R.P. Erickson A rapid method for detection of the Y-chromosomal DNA from dried blood specimens by the polymerase chain reaction Hum Genet 82 1989 271 274
4. S.C. Kogan M. Doherty J. Gitschier An improved method for prenatal diagnosis of genetic disease by analysis of amplified DNA sequences N Engl J Med 317 1987 985 990