Thymus directed immunotoxicity of airborne dust particles from upper silesia poland under acute extrapulmonary studies in mice

Journal of Toxicology and Environmental Health

Volumn 49, Issue 6, 1996, Pages 563-580

  Kozłowska, Ewa ^a   Krzystyniak, Krzysztof ^b   Drela, Nadzieja ^a   Grabarczyk, Piotr ^a   Izdebska Szymona, Krystyna ^a  

^a UNIVERSITY OF WARSAW   (Poland)

^b UNIVERSITÉ DU QUÉBEC À MONTRÉAL   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE; GAMMA INTERFERON; TUMOR NECROSIS FACTOR ALPHA;

AIRBORNE PARTICLE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL COUNT; CELL PROLIFERATION; CONTROLLED STUDY; DUST; FEMALE; IMMUNOTOXICITY; LYMPHOCYTE; MOUSE; NONHUMAN; ORGAN WEIGHT; POLAND; PRIORITY JOURNAL; SPLEEN; THYMOCYTE; THYMUS;

AIR POLLUTANTS, OCCUPATIONAL; ANALYSIS OF VARIANCE; ANIMALS; ANTIGENS, SURFACE; B-LYMPHOCYTES; CD4-POSITIVE T-LYMPHOCYTES; CD8-POSITIVE T-LYMPHOCYTES; CELLS, CULTURED; DNA ADDUCTS; DRUG SYNERGISM; ENVIRONMENTAL EXPOSURE; FEMALE; GENE EXPRESSION REGULATION; HETEROCYCLIC COMPOUNDS; INTERFERON TYPE II; KIDNEY; LETHAL DOSE 50; LIVER; LYMPHOCYTE COUNT; METALS; MICE; MICE, INBRED BALB C; POLAND; POLYCYCLIC HYDROCARBONS, AROMATIC; SPLEEN; THYMUS GLAND; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0030447853     PISSN: 00984108     EISSN: None     Source Type: Journal    
DOI: 10.1080/009841096160628     Document Type: Article

References (33)

1. Abo, T. 1992. Extrathymic differentiation of T lymphocytes and its biological function. Biomed. Res. 13:1-39.
2. Beck, E. G., and Schmidt, P. 1993. Environmental medicine group diagnosis of children-Studies from 1982 to 1990. Zentralbl. Hyg. Umweldmed. 193:395-418.
3. Bernier, J., Girard, D., Krzystyniak, K., Chevalier, G., Trottier, B., Nadeau, D., Rola-Pleszczynski, M., and Fournier, M. 1995. Immunotoxicity of aminocarb. III. Exposure route-dependent immunomodulation by aminocarb in mice. Toxicology 99:146-153.
4. Bonomo, A., Kehn, P., and Shevach, P. 1994. Premature escape of double-positive thymocytes to the periphery of young mice. J. Immunol. 152:1509-1514.
5. Burchiel, S. W., Davis, D. A. P., Ray, S. D., and Barton, S. L. 1993. DMBA induces programmed cell death (apoptosis) in the A20.1murine B cell lymphoma. Fundam. Appl. Toxicol. 21:120-124.
6. Chorazy, M., Szeliga, J., Ströyk, M., and Cimander, B. 1994. Ambient air pollutants in Upper Silesia: Partial chemical composition and biological activity. Environ. Health Perspect. 102(suppl. 4):61-66.
7. Descotes, J. 1988. Immunotoxicity of chemicals. In Immunotoxicology of drugs and chemicals, pp. 297-441. Amsterdam: Elsevier.
8. Foth, H. 1995. Role of the lung in accumulation and metabolism of xenobiotic compounds- Implications for chemically induced toxicity. Crit. Rev. Toxicol. 25:165-205.
9. Graham, J. A., and Gardner, D. 1985. Immunotoxicity of air pollutants. In Immunotoxicology and immunopharmacology, eds. J. H. Dean, M. I. Luster, A. E. Munson, and H. Amos, pp. 367-380. New York: Raven Press.
10. Hadnagy, W., and Seemayer, N. H. 1994. Inhibition of phagocytosis of human macrophages induced by airborne particulates. Toxicol. Lett. 72:23-31.
11. Hartmann, A., Niess, A. M., Grunert-Fuchs, M., and Speit, B. G. 1995. Vitamin E prevents exercise-induced DNA damage. Mutat. Res. 346:195-202.
12. Hemminiki, K., Grzybowska, E., Chorazy, M., Twardowska-Saucha, K., Sroczynski, J. W., Putnam, K. L., Randerrath, K., Phillips, D. H., Hewer, A., Santella, R. M., and Perera, F. P. 1990. DNA adducts in humans related to occupational and environmental exposure to aromatic compounds. In Complex mixtures and cancer risk, eds. H. Vainio, M. Sorga, and A. J. McMichael, pp. 181-192. Lyon: IARC.
13. Herr, C., Schuurman, H. J., Houben, G. F., Pieters, H. H., Penninks, A. H., and van Loveren, H. 1995. The SCID-hu mouse as a tool in immunotoxicological risk assessment: Effects of 2-acetyl-4(5)-tetrahydroxybutyl-imidazole (THI) and di-n-butyltin dichloride (DBTC) on the human thymus in SCID-hu mice. Toxicology 100:203-211.
14. Hosseinzadeh, H., and Goldschneider, I. 1993. Demonstration of large-scale migration of cortical thymocytes to peripheral lymphoid tissues in cyclosporin A-treated rats. J. Exp. Med. 178:285-298.
15. Justement, L. B., Brown, V. K., and Lin, J. 1994. Regulation of B-cell activation by CD45: A question of mechanisms. Immunol. Today 15:399-406.
16. Kelly, K. A., and Scollay, R. 1990. Analysis of recent thymic emigrants with subsets- and maturity-related markers. Int. Immunol. 2:419-432.
17. Krzystyniak, K. 1990. Czynniki srodowiskowe w immunopatologii odpornosci przeciwwirusowej (Environmental factors in the immunopathology of antiviral resistance). Ann. Acad. Med. Siles. Suppl. 10:223-235.
18. Krzystyniak, K., Koz-l owska, E., Desjardins, R., Drela, N., Kowalczyk, R., Karwowska, K., and Izdebska-Szymona, K. 1995a. Different T cell activation by streptozotocin and Freund's adjuvant in popliteal lymph node (PLN). Int. J. Immunopharmacol. 17:189-196.
19. Krzystyniak, K., T ryphonas, H., and Fournier, M. 1995b. Approaches to the evaluation of chemical-induced immunotoxicity. Environ. Health Perspect. 103(suppl.):17-22.
20. Lewtas, J. 1994. Human exposure to complex mixtures of air pollutants. Toxicol. Lett. 72:163-169.
21. Litchfield, J. T., and Wilcoxon, F. 1949. A simplified method of evaluating dose-effect experiments. J. Pharmacol. Exp. Ther. 96:99-113.
22. Luster, M. I., Portier, C., Pait, G. D., White, K. L., Gennings, C., Munson, A., and Rosenthal, G. J. 1992. Risk assessment in immunotoxicology. I. Sensitivity and predictability of immune tests. Fundam. Appl. Toxicol. 8:200-210.
23. Motykiewicz, G. 1995. Application of biomarkers in heavily polluted industrialized areas of countries of Central and Eastern Europe. Toxicology 101:117-123.
24. Motykiewicz, G., Szeliga, J., Cimander, B., and Chorazy, M. 1989. Seasonal variations in mutagenic activity of air pollutants at an industrial districts of Silesia. Mutat. Res. 223:243-251.
25. Motykiewicz, G., Michalska, J., Szeliga, J., Konopacka, M., Tkocz, A., Hadagny, W., Chorazy, M., and Seemeyer, N. H. 1990. Genotoxicity of airborne suspended matter determined in vitro and in vivo short-term assays. In Environmental hygiene II, eds. N. H. Seemeyer and W. Hadagny, pp. 17-21. Berlin: Springer-Verlag.
26. Pallardy, M. J., House, R. V., and Dean, J. 1989. Molecular mechanism of 7,12-dimethyl-benz[a]anthracene-induced immunosuppression: Evidence for action via the interleukin-2 pathway. Mol. Pharmacol. 36:128-133.
27. Payette, Y., Lachapelle, M., Daniel, C., Bernier, J., Fournier, M., and Krzystyniak, K. 1995. Decreased interleukin-2 receptor and cell cycle changes in murine lymphocytes exposed in vitro to low doses of cadmium chloride. Int.J. Immunopharmacol. 17:235-246.
28. Shopp, G. M., McCay, J. A., and Holsapple, M. P. 1985. Suppression of the antibody response by formamimide pesticide: Dependence on the route and exposure. J. Toxicol. Environ. Health 15:283-293.
29. Szczeklik, A., Szczeklik, J., Gal uszka, Z., Musia-t, J., Kolarzyk, E., and Targosz, D. 1994. Humoral immunosuppression in men exposed to polycyclic aromatic hydrocarbons and related carcinogens in polluted environments. Environ. Health Perspect. 102:302-304.
30. Wang, J. 1992. Investigation of the immune function of coke-oven workers in a gas factory. Chung-Hua Yu Fang I Hsueh Tsa Chich 26:339-341.
31. Wong, S., Fournier, M., Coderre, D., Banska, W., and Krzystyniak, K. 1992. Environmental immunotoxicology. In Animal biomarkers as pollution indicators, ed. D. Peakall, pp. 167-189. London: Chapman and Hall.
32. Wojtyniak, B., Gorynski, P., and Piekarski, T. 1994. Air pollution and population health in Poland-Selected issues. Zentralbl. Bakteriol. 281:317-323.
33. Wydawnictwo WSSE. 1981. Zanieczyszczenie atmosfery w wojewodztwie katowickim w roku 1980. Katowice: Wyd. WSSE w Katowicach.